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AGIO — AGIOS PHARMACEUTICALS INC

Reported value held$1.12B
Funds holding (latest)46
SectorHealth Care
Funds holding (Q2 2026)30
Institutional value$954.60M · 25.94M sh
New / Add / Cut / Exit1 / 21 / 6 / 4
Top-5 / Top-10 concentration70.8% / 86.3%
Institutional holdings change Accumulating +13.4% (+3.06M sh)
Institutional value change Up +24.9%

As of Q2 2026, 30 SEC-registered investment managers reported holding AGIO (AGIOS PHARMACEUTICALS INC) in their latest 13F filings, with a combined reported value of $954.60M across 25.94M shares. That is +13.4% by share count (+3.06M shares) versus the previous quarter, while reported value moved +24.9%. Ownership is concentrated: the five largest holders account for 70.8% of reported value and the top ten for 86.3%.

Compared with the prior quarter, 1 opened new positions, 21 added to existing stakes, 6 trimmed, 4 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

AGIO is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 30 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 6.46M $239.58M 0.00% Add
Farallon Capital Management history 5.92M $219.59M 1.02% Add
D. E. Shaw & Co history 3.11M $115.30M 0.06% Add
Geode Capital Management history 1.57M $58.43M 0.00% Add
Goldman Sachs Group history 1.15M $42.71M 0.01% Add
UBS Group AG history 985.83K $36.58M 0.01% Add
Morgan Stanley history 963.26K $35.75M 0.00% Hold
Arrowstreet Capital history 810.53K $30.08M 0.01% Add
AQR Capital Management history 684.34K $25.40M 0.01% Add
Northern Trust Corp history 554.71K $20.59M 0.00% Add
Charles Schwab Investment Management history 538.13K $19.97M 0.00% Add
Two Sigma Investments history 536.38K $19.91M 0.01% Add
Bank of America Corp history 507.87K $18.85M 0.00% Hold
Point72 Asset Management history 506.34K $18.79M 0.07% Add
Legal & General Investment Management America history 434.72K $16.13M 0.00% Add
BNY Mellon history 198.69K $7.37M 0.00% Add
Invesco Ltd history 168.15K $6.24M 0.00% Add
Citigroup Inc history 155.17K $5.76M 0.00% Add
Marshall Wace history 138.80K $5.15M 0.00% Reduce
Citadel Advisors history 88.80K $3.30M 0.00% Reduce
Deutsche Bank AG history 62.23K $2.31M 0.00% Add
Wells Fargo & Co history 53.24K $1.98M 0.00% Add
Fidelity Management & Research (FMR) history 39.07K $1.45M 0.00% Add
Manulife Financial history 37.73K $1.40M 0.00% Reduce
Wellington Management Group history 20.88K $774.67K 0.00% Reduce
CPP Investments history 16.50K $612.32K 0.00% Reduce
Prudential Financial history 9.96K $369.43K 0.00% Add
PNC Financial Services history 5.84K $216.57K 0.00% Add
JPMorgan Chase & Co history 300 $11.41K 0.00% New
T. Rowe Price Associates history 218.97K $8.13K 0.00% Reduce

Q1 2026 — 33 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 5.75M $194.69M 0.00% Add
Farallon Capital Management history 5.68M $192.29M 1.26% Add
D. E. Shaw & Co history 2.68M $90.70M 0.06% Add
Geode Capital Management history 1.47M $49.67M 0.00% Add
Morgan Stanley history 967.52K $32.73M 0.00% Add
Goldman Sachs Group history 817.68K $27.66M 0.00% Reduce
Citadel Advisors history 769.41K $26.03M 0.00% Reduce
Wellington Management Group history 641.49K $21.70M 0.00% Add
Northern Trust Corp history 509.27K $17.23M 0.00% Reduce
Bank of America Corp history 507.90K $17.18M 0.00% Reduce
Charles Schwab Investment Management history 477.03K $16.14M 0.00% Reduce
Marshall Wace history 448.12K $15.16M 0.01% Add
Legal & General Investment Management America history 423.92K $14.34M 0.00% Add
Two Sigma Investments history 251.64K $8.51M 0.01% Reduce
Arrowstreet Capital history 250.46K $8.47M 0.01% New
BNY Mellon history 186.79K $6.32M 0.00% Reduce
Invesco Ltd history 151.43K $5.12M 0.00% Add
Citigroup Inc history 142.90K $4.83M 0.00% Reduce
UBS Group AG history 132.54K $4.48M 0.00% Add
Deutsche Bank AG history 50.38K $1.70M 0.00% Reduce
Manulife Financial history 50.05K $1.69M 0.00% Reduce
AQR Capital Management history 36.41K $1.23M 0.00% Add
Millennium Management history 32.14K $1.09M 0.00% Reduce
Point72 Asset Management history 29.40K $994.60K 0.00% Reduce
CPP Investments history 24.40K $825.45K 0.00% Add
Janus Henderson Group history 23.80K $804.70K 0.00% Hold
Wells Fargo & Co history 22.76K $770.07K 0.00% Reduce
Balyasny Asset Management history 18.01K $609.24K 0.00% Reduce
Fidelity Management & Research (FMR) history 9.12K $308.56K 0.00% Reduce
Prudential Financial history 9.04K $305.99K 0.00% Reduce
Franklin Resources history 8.29K $280.35K 0.00% New
PNC Financial Services history 4.94K $167.12K 0.00% Add
T. Rowe Price Associates history 298.78K $10.11K 0.00% Reduce

Q4 2025 — 34 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 5.59M $152.28M 0.00% Hold
BlackRock Inc history 5.24M $142.51M 0.00% Add
Farallon Capital Management history 5.16M $140.44M 0.66% Reduce
D. E. Shaw & Co history 1.86M $50.66M 0.03% Add
Citadel Advisors history 1.61M $43.79M 0.01% Add
Geode Capital Management history 1.41M $38.48M 0.00% Hold
Goldman Sachs Group history 1.03M $28.14M 0.00% Add
Morgan Stanley history 894.04K $24.34M 0.00% Add
Balyasny Asset Management history 635.07K $17.29M 0.02% Add
Wellington Management Group history 597.83K $16.27M 0.00% Reduce
Bank of America Corp history 539.34K $14.68M 0.00% Reduce
Northern Trust Corp history 511.90K $13.93M 0.00% Reduce
Charles Schwab Investment Management history 482.62K $13.14M 0.00% Hold
Millennium Management history 418.27K $11.39M 0.01% Add
Marshall Wace history 353.64K $9.63M 0.01% Add
Legal & General Investment Management America history 328.21K $8.93M 0.00% Add
Two Sigma Investments history 300.16K $8.17M 0.01% Add
Point72 Asset Management history 200.00K $5.44M 0.01% Add
BNY Mellon history 196.89K $5.36M 0.00% Reduce
Moore Capital Management history 150.00K $4.08M 0.06% Add
Citigroup Inc history 148.04K $4.03M 0.00% Add
Invesco Ltd history 142.58K $3.88M 0.00% Add
UBS Group AG history 126.67K $3.45M 0.00% Reduce
Deutsche Bank AG history 122.88K $3.34M 0.00% Reduce
Prudential Financial history 81.06K $2.21M 0.00% Reduce
Manulife Financial history 70.26K $1.92M 0.00% Reduce
Wells Fargo & Co history 64.77K $1.76M 0.00% Add
JPMorgan Chase & Co history 30.00K $816.60K 0.00% Add
AQR Capital Management history 27.93K $754.00K 0.00% Reduce
Fidelity Management & Research (FMR) history 24.33K $662.38K 0.00% Add
Janus Henderson Group history 23.80K $648.23K 0.00% Hold
CPP Investments history 18.20K $495.40K 0.00% New
PNC Financial Services history 4.71K $128.21K 0.00% Add
T. Rowe Price Associates history 637.89K $17.36K 0.00% Reduce

Q3 2025 — 33 funds

FundSharesValuePortfolio WeightChange
Farallon Capital Management history 5.78M $232.05M 0.95% Hold
Vanguard Group history 5.60M $224.98M 0.00% Reduce
BlackRock Inc history 4.55M $182.47M 0.00% Reduce
Wellington Management Group history 2.47M $99.20M 0.02% Add
Geode Capital Management history 1.42M $56.86M 0.00% Add
Bank of America Corp history 1.13M $45.36M 0.00% Add
Deutsche Bank AG history 926.73K $37.20M 0.01% Add
Goldman Sachs Group history 804.77K $32.30M 0.00% Add
Citadel Advisors history 604.98K $24.28M 0.00% Reduce
Northern Trust Corp history 555.41K $22.29M 0.00% Hold
Balyasny Asset Management history 495.49K $19.89M 0.03% New
Charles Schwab Investment Management history 482.19K $19.35M 0.00% Add
Morgan Stanley history 417.00K $16.74M 0.00% Add
D. E. Shaw & Co history 367.75K $14.76M 0.01% Reduce
Legal & General Investment Management America history 322.93K $12.96M 0.00% Add
BNY Mellon history 270.10K $10.84M 0.00% Add
UBS Group AG history 242.81K $9.75M 0.00% Add
Marshall Wace history 226.82K $9.10M 0.01% Reduce
Invesco Ltd history 126.98K $5.10M 0.00% Add
Prudential Financial history 98.24K $3.94M 0.01% Reduce
Manulife Financial history 96.01K $3.85M 0.00% Reduce
AQR Capital Management history 91.64K $3.61M 0.00% Reduce
Two Sigma Investments history 59.63K $2.39M 0.00% New
Moore Capital Management history 55.00K $2.21M 0.03% Reduce
Wells Fargo & Co history 44.75K $1.80M 0.00% Add
Citigroup Inc history 43.62K $1.75M 0.00% Reduce
Janus Henderson Group history 23.80K $955.33K 0.00% Hold
Fidelity Management & Research (FMR) history 20.71K $831.36K 0.00% Add
JPMorgan Chase & Co history 18.40K $738.58K 0.00% Hold
Point72 Asset Management history 6.51K $261.19K 0.00% New
Millennium Management history 5.05K $202.67K 0.00% Reduce
PNC Financial Services history 4.55K $182.80K 0.00% Add
T. Rowe Price Associates history 1.66M $66.51K 0.01% Reduce

Q2 2025 — 42 funds

FundSharesValuePortfolio WeightChange
Farallon Capital Management history 5.77M $191.83M 0.83% Add
Vanguard Group history 5.68M $188.98M 0.00% Add
BlackRock Inc history 4.83M $160.77M 0.00% Reduce
BlackRock Inc history 4.83M $160.77M 0.00% Reduce
Geode Capital Management history 1.41M $46.76M 0.00% Add
Citadel Advisors history 1.15M $38.10M 0.01% Add
Citadel Advisors history 1.15M $38.10M 0.01% Add
Bank of America Corp history 1.12M $37.26M 0.00% Reduce
Deutsche Bank AG history 921.59K $30.65M 0.01% Reduce
Deutsche Bank AG history 921.59K $30.65M 0.01% Reduce
Marshall Wace history 684.67K $22.77M 0.03% Add
Goldman Sachs Group history 648.06K $21.55M 0.00% Reduce
Goldman Sachs Group history 648.06K $21.55M 0.00% Reduce
D. E. Shaw & Co history 596.20K $19.83M 0.01% Add
Northern Trust Corp history 556.80K $18.52M 0.00% Reduce
Charles Schwab Investment Management history 476.04K $15.83M 0.00% Add
Wellington Management Group history 422.13K $14.04M 0.00% Add
Millennium Management history 300.20K $9.98M 0.01% Add
Morgan Stanley history 291.96K $9.71M 0.00% Reduce
Morgan Stanley history 291.96K $9.71M 0.00% Reduce
BNY Mellon history 266.65K $8.87M 0.00% Add
Prudential Financial history 158.36K $5.27M 0.01% Reduce
Manulife Financial history 132.08K $4.39M 0.00% Hold
UBS Group AG history 118.83K $3.95M 0.00% Reduce
Invesco Ltd history 112.62K $3.75M 0.00% Add
Casdin Capital history 100.00K $3.33M 0.30% Reduce
AQR Capital Management history 96.90K $3.21M 0.00% Add
Moore Capital Management history 80.00K $2.66M 0.03% Add
Legal & General Investment Management America history 64.31K $2.14M 0.00% Add
Citigroup Inc history 56.49K $1.88M 0.00% Reduce
Franklin Resources history 50.11K $1.67M 0.00% Reduce
Wells Fargo & Co history 37.69K $1.25M 0.00% Reduce
Janus Henderson Group history 23.80K $790.77K 0.00% Hold
Fidelity Management & Research (FMR) history 18.59K $618.36K 0.00% Add
Fidelity Management & Research (FMR) history 18.59K $618.36K 0.00% Add
JPMorgan Chase & Co history 18.40K $611.98K 0.00% Reduce
JPMorgan Chase & Co history 18.40K $611.98K 0.00% Reduce
Norges Bank Investment Management history 6.76K $224.71K 0.00% Reduce
Norges Bank Investment Management history 6.76K $224.71K 0.00% Reduce
PNC Financial Services history 4.42K $146.98K 0.00% Add
T. Rowe Price Associates history 2.27M $75.64K 0.01% Reduce
Lazard Asset Management history 534 $17 0.00% Reduce

Q1 2025 — 40 funds

FundSharesValuePortfolio WeightChange
Farallon Capital Management history 5.70M $167.02M 0.93% Hold
Vanguard Group history 5.60M $164.21M 0.00% Hold
BlackRock Inc history 5.11M $149.69M 0.00% Add
BlackRock Inc history 5.11M $149.69M 0.00% Add
Geode Capital Management history 1.39M $40.87M 0.00% Add
Bank of America Corp history 1.14M $33.27M 0.00% Add
JPMorgan Chase & Co history 1.05M $30.75M 0.01% Add
JPMorgan Chase & Co history 1.05M $30.75M 0.01% Add
Citadel Advisors history 934.90K $27.39M 0.01% Reduce
Citadel Advisors history 934.90K $27.39M 0.01% Reduce
Deutsche Bank AG history 928.97K $27.22M 0.01% Reduce
Deutsche Bank AG history 928.97K $27.22M 0.01% Reduce
Goldman Sachs Group history 658.65K $19.30M 0.00% Add
Goldman Sachs Group history 658.65K $19.30M 0.00% Add
Northern Trust Corp history 576.26K $16.88M 0.00% Reduce
D. E. Shaw & Co history 554.82K $16.26M 0.02% Add
Marshall Wace history 520.87K $15.26M 0.02% Reduce
Charles Schwab Investment Management history 464.96K $13.62M 0.00% Reduce
Citigroup Inc history 296.13K $8.68M 0.01% Add
Morgan Stanley history 294.62K $8.63M 0.00% Reduce
Morgan Stanley history 294.62K $8.63M 0.00% Reduce
BNY Mellon history 263.45K $7.72M 0.00% Reduce
Casdin Capital history 250.00K $7.33M 0.60% Hold
Prudential Financial history 204.24K $5.98M 0.01% Add
UBS Group AG history 131.64K $3.86M 0.00% Reduce
Manulife Financial history 131.57K $3.86M 0.00% Add
Invesco Ltd history 107.37K $3.15M 0.00% Add
Wells Fargo & Co history 68.14K $2.00M 0.00% Add
Franklin Resources history 68.07K $1.99M 0.00% Add
Legal & General Investment Management America history 60.04K $1.76M 0.00% Reduce
Moore Capital Management history 60.00K $1.76M 0.04% Hold
Millennium Management history 53.07K $1.56M 0.00% Add
AQR Capital Management history 51.49K $1.50M 0.00% Add
Janus Henderson Group history 23.80K $721.17K 0.00% Hold
Wellington Management Group history 24.46K $716.74K 0.00% Reduce
Fidelity Management & Research (FMR) history 17.81K $521.72K 0.00% Reduce
Fidelity Management & Research (FMR) history 17.81K $521.72K 0.00% Reduce
PNC Financial Services history 3.58K $104.95K 0.00% Add
T. Rowe Price Associates history 2.30M $67.43K 0.01% Reduce
Lazard Asset Management history 2.66K $77 0.00% New

View all 46 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021
BlackRock Inc 6.46M 5.75M 5.24M 4.55M 4.83M 5.11M 5.02M 5.02M — — — — — — — — — — — —
Farallon Capital Management 5.92M 5.68M 5.16M 5.78M 5.77M 5.70M 5.67M 5.66M 5.65M 5.59M 4.17M 2.75M 2.69M 2.09M 2.03M 1.50M 1.33M 1.33M 1.26M 818.77K
D. E. Shaw & Co 3.11M 2.68M 1.86M 367.75K 596.20K 554.82K 516.48K 532.40K 678.23K 362.13K 216.48K 158.28K 95.86K 102.15K 165.80K 291.29K 276.42K 80.54K 143.87K 140.75K
Geode Capital Management 1.57M 1.47M 1.41M 1.42M 1.41M 1.39M 1.35M 1.36M 1.35M 1.28M 1.25M 1.20M 1.16M 1.09M 1.06M 1.03M 1.12M 1.02M 1.04M 1.05M
Goldman Sachs Group 1.15M 817.68K 1.03M 804.77K 648.06K 658.65K 567.17K 476.66K 549.00K 539.58K 607.94K 805.44K 799.61K 964.16K 1.56M 1.80M 1.67M 1.82M 1.88M 1.85M
UBS Group AG 985.83K 132.54K 126.67K 242.81K 118.83K 131.64K 234.34K 114.19K 69.36K 170.88K 1.85K 60.39K 72.30K 85.83K 92.08K 14.66K 79.14K 45.86K 185.43K 93.92K
Morgan Stanley 963.26K 967.52K 894.04K 417.00K 291.96K 294.62K 378.09K 348.97K 596.67K 1.18M 493.59K 374.13K 391.47K 310.78K 366.52K 279.53K 416.14K 330.53K 257.94K 176.29K
Arrowstreet Capital 810.53K 250.46K — — — — — — — — — — — — — — — — — —
AQR Capital Management 684.34K 36.41K 27.93K 91.64K 96.90K 51.49K 30.86K 138.14K 33.16K 11.18K — — 7.72K — — — — — — 34.53K
Northern Trust Corp 554.71K 509.27K 511.90K 555.41K 556.80K 576.26K 595.48K 590.11K 586.27K 590.49K 620.24K 612.74K 709.71K 674.31K 689.02K 673.07K 531.45K 537.32K 632.29K 604.64K
Charles Schwab Investment Management 538.13K 477.03K 482.62K 482.19K 476.04K 464.96K 472.55K 465.62K 457.53K 440.23K 456.39K 451.69K 437.27K 429.81K 429.77K 420.56K 391.59K 395.25K 385.63K 410.60K
Two Sigma Investments 536.38K 251.64K 300.16K 59.63K — — 109.37K — — 122.28K 45.92K — — — — — — — — —
Bank of America Corp 507.87K 507.90K 539.34K 1.13M 1.12M 1.14M 404.90K 333.07K 326.78K 381.73K 205.95K 274.59K 313.01K 482.83K 263.47K 283.40K 162.16K 267.14K 282.18K 136.46K
Point72 Asset Management 506.34K 29.40K 200.00K 6.51K — — — 150.00K — — — — — — — — — — — —
Legal & General Investment Management America 434.72K 423.92K 328.21K 322.93K 64.31K 60.04K 71.68K 73.10K 60.73K 55.49K 54.98K 54.02K 51.94K 48.66K 47.40K 46.19K 47.09K 48.20K 48.46K 49.35K
BNY Mellon 198.69K 186.79K 196.89K 270.10K 266.65K 263.45K 265.51K 178.43K 223.15K 195.96K 203.76K 205.88K 209.95K 206.71K 205.67K 320.96K 300.55K 368.92K 369.14K 279.45K
Invesco Ltd 168.15K 151.43K 142.58K 126.98K 112.62K 107.37K 83.52K 118.95K 118.02K 76.20K 80.09K 204.45K 75.70K 71.99K 87.61K 74.28K 78.92K 76.64K 33.13K 37.82K
Citigroup Inc 155.17K 142.90K 148.04K 43.62K 56.49K 296.13K 253.15K 123.46K 24.32K 248.08K 164.83K 182.39K 125.33K 246.87K 214.16K 227.12K 176.88K 91.96K 153.05K 54.94K
Marshall Wace 138.80K 448.12K 353.64K 226.82K 684.67K 520.87K 631.63K 1.26M 1.13M 278.00K — 58.04K — — — 14.41K 43.56K — 14.58K —
Citadel Advisors 88.80K 769.41K 1.61M 604.98K 1.15M 934.90K 1.48M 39.54K 159.94K 1.04M 1.09M 452.12K 199.19K 320.95K 281.52K 371.85K 407.78K 105.16K 67.53K 127.68K

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