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SYRE — SPYRE THERAPEUTICS INC · All Fund Holders

Funds holding (latest): 40 · Reported value held: $3.55B

FundQuarterSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history Q2 2026 13.03M $1.16B 0.06% Add
BlackRock Inc history Q2 2026 6.51M $577.66M 0.01% Add
Geode Capital Management history Q2 2026 2.56M $239.26M 0.01% Add
Capital World Investors history Q2 2026 2.32M $205.57M 0.03% Add
Bank of America Corp history Q2 2026 1.78M $157.84M 0.01% Add
Wellington Management Group history Q2 2026 1.58M $140.41M 0.03% Reduce
Vanguard Group history Q4 2025 4.04M $132.19M 0.00% Add
Goldman Sachs Group history Q2 2026 1.48M $131.22M 0.04% Add
Franklin Resources history Q2 2026 1.47M $130.77M 0.03% Add
JPMorgan Chase & Co history Q2 2026 1.09M $98.87M 0.01% New
Marshall Wace history Q2 2026 991.69K $88.04M 0.07% Add
Janus Henderson Group history Q1 2026 1.66M $83.59M 0.04% Reduce
UBS Group AG history Q2 2026 843.07K $74.85M 0.03% Add
Northern Trust Corp history Q2 2026 674.53K $59.88M 0.01% Add
Charles Schwab Investment Management history Q2 2026 652.96K $57.97M 0.01% Add
Morgan Stanley history Q2 2026 499.96K $44.39M 0.00% Add
BNY Mellon history Q2 2026 245.19K $21.77M 0.00% Add
Point72 Asset Management history Q4 2025 662.35K $21.70M 0.03% New
Millennium Management history Q2 2026 196.71K $17.46M 0.01% Add
Farallon Capital Management history Q2 2024 666.00K $15.66M 0.07% Add
Deutsche Bank AG history Q2 2026 174.46K $15.49M 0.01% Add
Balyasny Asset Management history Q2 2026 147.04K $13.05M 0.02% Add
Invesco Ltd history Q2 2026 120.54K $10.70M 0.00% Reduce
Manulife Financial history Q2 2026 104.52K $9.28M 0.01% Reduce
Prudential Financial history Q2 2026 87.37K $7.76M 0.01% Add
Citigroup Inc history Q2 2026 82.59K $7.33M 0.00% Add
Wells Fargo & Co history Q2 2026 82.51K $7.32M 0.00% Add
Principal Global Investors history Q2 2026 59.75K $5.30M 0.00% Add
Royce & Associates history Q2 2026 51.79K $4.60M 0.04% New
Legal & General Investment Management America history Q2 2026 49.14K $4.36M 0.00% Add
D. E. Shaw & Co history Q2 2026 26.45K $2.35M 0.00% New
AQR Capital Management history Q2 2026 22.94K $2.04M 0.00% Add
Soros Fund Management history Q1 2025 125.00K $2.02M 0.03% Reduce
Norges Bank Investment Management history Q2 2024 70.84K $1.67M 0.00% New
Two Sigma Investments history Q2 2026 12.77K $1.13M 0.00% New
Citadel Advisors history Q2 2026 7.90K $701.36K 0.00% Reduce
Renaissance Technologies history Q2 2025 30.94K $463.11K 0.00% New
T. Rowe Price Associates history Q2 2026 2.96M $262.87K 0.03% Add
Amundi US history Q2 2026 2.79K $247.96K 0.00% New
PNC Financial Services history Q2 2026 914 $81.14K 0.00% Add

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