SEPN — SEPTERNA INC
As of Q2 2026, 32 SEC-registered investment managers reported holding SEPN (SEPTERNA INC) in their latest 13F filings, with a combined reported value of $272.76M across 8.18M shares. That is -0.2% by share count (-15.20K shares) versus the previous quarter, while reported value moved +39.1%. Ownership is concentrated: the five largest holders account for 80.8% of reported value and the top ten for 91.0%.
Compared with the prior quarter, 8 opened new positions, 16 added to existing stakes, 6 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
SEPN is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
| Fund | Quarter | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|---|
| Goldman Sachs Group history | Q2 2026 | 3.06M | $102.57M | 0.01% | Add |
| BlackRock Inc history | Q2 2026 | 1.93M | $64.71M | 0.00% | Add |
| Vanguard Group history | Q4 2025 | 1.51M | $42.05M | 0.00% | Reduce |
| Geode Capital Management history | Q2 2026 | 679.16K | $22.75M | 0.00% | Add |
| Janus Henderson Group history | Q1 2026 | 890.75K | $21.33M | 0.01% | New |
| Casdin Capital history | Q2 2026 | 553.27K | $18.53M | 0.93% | Hold |
| Balyasny Asset Management history | Q2 2026 | 350.44K | $11.74M | 0.01% | Add |
| Two Sigma Investments history | Q2 2026 | 220.88K | $7.40M | 0.01% | Add |
| Northern Trust Corp history | Q2 2026 | 201.13K | $6.74M | 0.00% | Add |
| Charles Schwab Investment Management history | Q2 2026 | 187.04K | $6.26M | 0.00% | Add |
| Morgan Stanley history | Q2 2026 | 134.38K | $4.50M | 0.00% | Add |
| UBS Group AG history | Q2 2026 | 89.87K | $3.01M | 0.00% | Reduce |
| JPMorgan Chase & Co history | Q2 2026 | 85.30K | $2.96M | 0.00% | New |
| Citadel Advisors history | Q2 2026 | 88.15K | $2.95M | 0.00% | New |
| Lazard Asset Management history | Q2 2026 | 75.42K | $2.53M | 0.00% | New |
| Arrowstreet Capital history | Q2 2026 | 74.65K | $2.50M | 0.00% | New |
| BNY Mellon history | Q2 2026 | 56.18K | $1.88M | 0.00% | Reduce |
| Millennium Management history | Q2 2026 | 50.56K | $1.69M | 0.00% | Reduce |
| D. E. Shaw & Co history | Q2 2026 | 46.48K | $1.56M | 0.00% | New |
| Renaissance Technologies history | Q2 2026 | 41.42K | $1.39M | 0.00% | Add |
New Positions (Q2 2026)
- JPMorgan Chase & Co 85.30K sh · $2.96M
- Citadel Advisors 88.15K sh · $2.95M
- Lazard Asset Management 75.42K sh · $2.53M
- Arrowstreet Capital 74.65K sh · $2.50M
- D. E. Shaw & Co 46.48K sh · $1.56M
- Franklin Resources 18.61K sh · $623.15K
- CPP Investments 8.90K sh · $298.06K
- Manulife Financial 6.30K sh · $211.12K
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 890.75K sh · $21.33M
- Marshall Wace sold 39.84K sh · $957.35K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 |
|---|---|---|---|---|---|---|---|
| Goldman Sachs Group | 1.67M | 1.45M | 1.42M | 1.45M | 2.72M | 2.91M | 3.06M |
| BlackRock Inc | 1.68M | 1.26M | 1.39M | 1.46M | 1.80M | 1.82M | 1.93M |
| Geode Capital Management | 380.58K | 409.64K | 487.96K | 545.70K | 572.73K | 645.15K | 679.16K |
| Casdin Capital | 553.27K | 553.27K | 553.27K | 553.27K | 553.27K | 553.27K | 553.27K |
| Balyasny Asset Management | — | — | — | — | 3.57K | 236.68K | 350.44K |
| Two Sigma Investments | — | 74.84K | 77.64K | 92.33K | 92.81K | 75.37K | 220.88K |
| Northern Trust Corp | 147.78K | 158.04K | 154.34K | 167.34K | 154.20K | 164.53K | 201.13K |
| Charles Schwab Investment Management | 139.62K | 118.45K | 154.78K | 186.90K | 187.24K | 181.58K | 187.04K |
| Morgan Stanley | 41.91K | 91.04K | 84.86K | 54.46K | 103.98K | 110.53K | 134.38K |
| UBS Group AG | 108.45K | 239.93K | 72.33K | 59.05K | 68.82K | 116.98K | 89.87K |
| JPMorgan Chase & Co | 38.02K | 8.79K | 10.10K | 8.74K | 68.34K | — | 85.30K |
| Citadel Advisors | 404.88K | 18.90K | 130.27K | 25.00K | 87.84K | — | 88.15K |
| Lazard Asset Management | — | — | — | — | — | — | 75.42K |
| Arrowstreet Capital | — | — | — | — | — | — | 74.65K |
| BNY Mellon | 38.09K | 38.38K | 48.49K | 51.63K | 55.33K | 58.71K | 56.18K |
| Millennium Management | — | 436.56K | 51.94K | 384.20K | 107.46K | 124.10K | 50.56K |
| D. E. Shaw & Co | — | — | — | — | — | — | 46.48K |
| Renaissance Technologies | — | — | — | — | — | 37.70K | 41.42K |
| Bank of America Corp | 78.74K | 11.56K | 99.21K | 51.49K | 37.59K | 25.97K | 35.88K |
| Invesco Ltd | 12.15K | 12.20K | 11.83K | 177.07K | 162.01K | 82.87K | 24.09K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details