MAZE — MAZE THERAPEUTICS INC
Reported value held$533.48M
Funds holding (latest)37
SectorHealth Care
Funds holding (Q2 2026)31
Institutional value$373.98M · 12.69M sh
New / Add / Cut / Exit2 / 21 / 7 / 3
Top-5 / Top-10 concentration60.0% / 86.1%
Institutional holdings change
Accumulating +8.1%
(+949.20K sh)
Institutional value change
Up +7.8%
As of Q2 2026, 31 SEC-registered investment managers reported holding MAZE (MAZE THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $373.98M across 12.69M shares. That is +8.1% by share count (+949.20K shares) versus the previous quarter, while reported value moved +7.8%. Ownership is concentrated: the five largest holders account for 60.0% of reported value and the top ten for 86.1%.
Compared with the prior quarter, 2 opened new positions, 21 added to existing stakes, 7 trimmed, 3 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
MAZE is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 31 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 3.50M | $104.52M | 0.00% | Add |
| Farallon Capital Management history | 1.11M | $33.06M | 0.15% | Add |
| Fidelity Management & Research (FMR) history | 1.06M | $31.54M | 0.00% | Add |
| JPMorgan Chase & Co history | 964.01K | $28.00M | 0.00% | New |
| Marshall Wace history | 914.57K | $27.29M | 0.02% | Add |
| Citadel Advisors history | 874.88K | $26.11M | 0.00% | Add |
| Geode Capital Management history | 858.05K | $25.61M | 0.00% | Add |
| Casdin Capital history | 843.86K | $25.18M | 1.26% | Add |
| Hillhouse Capital (HHLR Advisors) history | 366.03K | $10.92M | 1.31% | Hold |
| Bank of America Corp history | 321.23K | $9.59M | 0.00% | Add |
| Northern Trust Corp history | 294.74K | $8.80M | 0.00% | Add |
| Goldman Sachs Group history | 293.14K | $8.75M | 0.00% | Add |
| Charles Schwab Investment Management history | 260.57K | $7.78M | 0.00% | Add |
| Two Sigma Investments history | 192.95K | $5.76M | 0.00% | Add |
| Morgan Stanley history | 135.17K | $4.03M | 0.00% | Reduce |
| BNY Mellon history | 97.59K | $2.91M | 0.00% | Add |
| UBS Group AG history | 84.68K | $2.53M | 0.00% | Reduce |
| Wellington Management Group history | 82.72K | $2.47M | 0.00% | Add |
| Franklin Resources history | 80.22K | $2.39M | 0.00% | Add |
| Deutsche Bank AG history | 34.99K | $1.04M | 0.00% | Add |
| Wells Fargo & Co history | 32.05K | $956.28K | 0.00% | Add |
| Citigroup Inc history | 30.27K | $903.11K | 0.00% | Add |
| Invesco Ltd history | 28.37K | $846.62K | 0.00% | Reduce |
| AQR Capital Management history | 27.16K | $810.49K | 0.00% | Reduce |
| Balyasny Asset Management history | 20.19K | $602.47K | 0.00% | Reduce |
| Manulife Financial history | 16.40K | $489.44K | 0.00% | Add |
| Legal & General Investment Management America history | 15.78K | $470.90K | 0.00% | Add |
| D. E. Shaw & Co history | 12.02K | $358.65K | 0.00% | Reduce |
| CPP Investments history | 9.10K | $271.54K | 0.00% | New |
| T. Rowe Price Associates history | 132.87K | $3.96K | 0.00% | Add |
| PNC Financial Services history | 32 | $955 | 0.00% | Reduce |
Q1 2026 — 32 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Janus Henderson Group history | 2.86M | $85.28M | 0.04% | Reduce |
| BlackRock Inc history | 2.57M | $76.73M | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 864.21K | $25.80M | 0.00% | Add |
| Citadel Advisors history | 809.21K | $24.16M | 0.00% | Add |
| Casdin Capital history | 758.86K | $22.65M | 1.72% | Hold |
| Geode Capital Management history | 599.97K | $17.91M | 0.00% | Add |
| Balyasny Asset Management history | 461.15K | $13.77M | 0.02% | Add |
| Farallon Capital Management history | 373.00K | $11.13M | 0.07% | New |
| Hillhouse Capital (HHLR Advisors) history | 366.03K | $10.93M | 0.65% | Reduce |
| Marshall Wace history | 310.64K | $9.27M | 0.01% | Reduce |
| Goldman Sachs Group history | 279.71K | $8.35M | 0.00% | Add |
| Northern Trust Corp history | 211.38K | $6.31M | 0.00% | Add |
| Morgan Stanley history | 204.83K | $6.11M | 0.00% | Reduce |
| Bank of America Corp history | 195.08K | $5.82M | 0.00% | Add |
| Charles Schwab Investment Management history | 186.43K | $5.57M | 0.00% | Add |
| UBS Group AG history | 93.90K | $2.80M | 0.00% | Add |
| Invesco Ltd history | 86.42K | $2.58M | 0.00% | Reduce |
| BNY Mellon history | 74.27K | $2.22M | 0.00% | Add |
| Wellington Management Group history | 60.59K | $1.81M | 0.00% | Reduce |
| Franklin Resources history | 59.64K | $1.78M | 0.00% | Add |
| D. E. Shaw & Co history | 45.64K | $1.36M | 0.00% | Add |
| Millennium Management history | 29.89K | $892.28K | 0.00% | Reduce |
| AQR Capital Management history | 27.95K | $834.16K | 0.00% | Add |
| Deutsche Bank AG history | 20.26K | $604.85K | 0.00% | Add |
| Two Sigma Investments history | 15.85K | $472.97K | 0.00% | Add |
| Renaissance Technologies history | 15.80K | $471.63K | 0.00% | Reduce |
| Manulife Financial history | 14.57K | $434.92K | 0.00% | Add |
| Wells Fargo & Co history | 10.37K | $309.51K | 0.00% | Reduce |
| Citigroup Inc history | 8.56K | $255.61K | 0.00% | Reduce |
| Legal & General Investment Management America history | 5.79K | $172.78K | 0.00% | Add |
| T. Rowe Price Associates history | 122.69K | $3.66K | 0.00% | Add |
| PNC Financial Services history | 58 | $1.73K | 0.00% | Hold |
Q4 2025 — 33 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Janus Henderson Group history | 3.14M | $130.20M | 0.06% | Add |
| BlackRock Inc history | 2.29M | $94.76M | 0.00% | Add |
| Vanguard Group history | 1.70M | $70.31M | 0.00% | Add |
| Marshall Wace history | 847.47K | $35.11M | 0.03% | Add |
| Casdin Capital history | 758.86K | $31.44M | 1.95% | Hold |
| Fidelity Management & Research (FMR) history | 728.61K | $30.19M | 0.00% | Add |
| Geode Capital Management history | 527.28K | $21.85M | 0.00% | Add |
| Hillhouse Capital (HHLR Advisors) history | 457.54K | $18.96M | 0.61% | Hold |
| Citadel Advisors history | 448.22K | $18.57M | 0.00% | New |
| Morgan Stanley history | 258.09K | $10.69M | 0.00% | Add |
| Balyasny Asset Management history | 199.21K | $8.25M | 0.01% | Reduce |
| Northern Trust Corp history | 176.26K | $7.30M | 0.00% | Hold |
| Charles Schwab Investment Management history | 175.97K | $7.29M | 0.00% | Add |
| Millennium Management history | 154.47K | $6.40M | 0.00% | New |
| Invesco Ltd history | 134.03K | $5.55M | 0.00% | Add |
| Goldman Sachs Group history | 114.45K | $4.74M | 0.00% | New |
| Wellington Management Group history | 61.20K | $2.54M | 0.00% | New |
| BNY Mellon history | 60.44K | $2.50M | 0.00% | Add |
| Franklin Resources history | 55.23K | $2.29M | 0.00% | Add |
| D. E. Shaw & Co history | 33.69K | $1.40M | 0.00% | New |
| UBS Group AG history | 28.70K | $1.19M | 0.00% | Add |
| AQR Capital Management history | 27.44K | $1.14M | 0.00% | Reduce |
| Renaissance Technologies history | 27.10K | $1.12M | 0.00% | Reduce |
| Wells Fargo & Co history | 24.01K | $994.65K | 0.00% | Add |
| JPMorgan Chase & Co history | 20.01K | $828.89K | 0.00% | Add |
| Bank of America Corp history | 18.38K | $761.52K | 0.00% | Add |
| Deutsche Bank AG history | 15.52K | $643.08K | 0.00% | Add |
| Citigroup Inc history | 11.25K | $466.17K | 0.00% | Add |
| Two Sigma Investments history | 7.25K | $300.16K | 0.00% | Reduce |
| Manulife Financial history | 6.90K | $285.74K | 0.00% | New |
| Legal & General Investment Management America history | 5.38K | $222.85K | 0.00% | Add |
| T. Rowe Price Associates history | 115.71K | $4.79K | 0.00% | Add |
| PNC Financial Services history | 58 | $2.40K | 0.00% | Reduce |
Q3 2025 — 28 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 1.33M | $34.62M | 0.00% | Add |
| BlackRock Inc history | 1.32M | $34.12M | 0.00% | Add |
| Marshall Wace history | 777.70K | $20.17M | 0.02% | Add |
| Casdin Capital history | 758.86K | $19.68M | 1.64% | Hold |
| Janus Henderson Group history | 751.87K | $19.49M | 0.01% | Reduce |
| Fidelity Management & Research (FMR) history | 655.61K | $17.00M | 0.00% | Add |
| Geode Capital Management history | 473.55K | $12.28M | 0.00% | Add |
| Hillhouse Capital (HHLR Advisors) history | 457.54K | $11.86M | 0.29% | Hold |
| Balyasny Asset Management history | 433.73K | $11.25M | 0.01% | New |
| Morgan Stanley history | 212.76K | $5.52M | 0.00% | Add |
| Northern Trust Corp history | 176.89K | $4.59M | 0.00% | Add |
| Charles Schwab Investment Management history | 167.93K | $4.35M | 0.00% | Add |
| Invesco Ltd history | 132.06K | $3.42M | 0.00% | Add |
| Harvard Management Company history | 92.40K | $2.40M | 0.11% | Reduce |
| Renaissance Technologies history | 86.10K | $2.23M | 0.00% | New |
| BNY Mellon history | 45.24K | $1.17M | 0.00% | Add |
| UBS Group AG history | 27.79K | $720.67K | 0.00% | Reduce |
| AQR Capital Management history | 27.61K | $716.06K | 0.00% | Add |
| Franklin Resources history | 18.20K | $471.87K | 0.00% | New |
| Wells Fargo & Co history | 14.78K | $383.22K | 0.00% | Add |
| Two Sigma Investments history | 11.15K | $289.12K | 0.00% | New |
| Bank of America Corp history | 9.57K | $248.25K | 0.00% | Add |
| Deutsche Bank AG history | 8.88K | $230.39K | 0.00% | Hold |
| JPMorgan Chase & Co history | 7.89K | $204.59K | 0.00% | Add |
| Legal & General Investment Management America history | 5.22K | $135.33K | 0.00% | Add |
| Citigroup Inc history | 269 | $6.98K | 0.00% | Reduce |
| PNC Financial Services history | 93 | $2.41K | 0.00% | New |
| T. Rowe Price Associates history | 10.47K | $272 | 0.00% | New |
Q2 2025 — 22 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Janus Henderson Group history | 1.40M | $17.35M | 0.01% | Add |
| Casdin Capital history | 758.86K | $9.31M | 0.85% | Reduce |
| Harvard Management Company history | 637.53K | $7.82M | 0.55% | Hold |
| BlackRock Inc history | 614.70K | $7.54M | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 554.53K | $6.80M | 0.00% | Reduce |
| Hillhouse Capital (HHLR Advisors) history | 457.54K | $5.61M | 0.18% | Hold |
| Vanguard Group history | 419.61K | $5.15M | 0.00% | Reduce |
| Geode Capital Management history | 231.24K | $2.84M | 0.00% | Add |
| Northern Trust Corp history | 85.55K | $1.05M | 0.00% | Add |
| Charles Schwab Investment Management history | 75.17K | $922.35K | 0.00% | Add |
| UBS Group AG history | 51.40K | $630.70K | 0.00% | Reduce |
| Morgan Stanley history | 31.78K | $389.95K | 0.00% | Add |
| AQR Capital Management history | 27.47K | $337.02K | 0.00% | New |
| BNY Mellon history | 21.55K | $264.37K | 0.00% | Add |
| Marshall Wace history | 19.60K | $240.46K | 0.00% | Hold |
| Invesco Ltd history | 18.43K | $226.14K | 0.00% | Reduce |
| Citigroup Inc history | 12.99K | $159.39K | 0.00% | Add |
| Deutsche Bank AG history | 8.88K | $109.02K | 0.00% | Hold |
| Bank of America Corp history | 5.78K | $70.95K | 0.00% | Add |
| Wells Fargo & Co history | 5.62K | $68.90K | 0.00% | Add |
| JPMorgan Chase & Co history | 4.37K | $53.57K | 0.00% | Reduce |
| Legal & General Investment Management America history | 4.24K | $52.05K | 0.00% | Add |
Q1 2025 — 24 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Janus Henderson Group history | 1.25M | $14.29M | 0.01% | New |
| Fidelity Management & Research (FMR) history | 968.38K | $10.66M | 0.00% | New |
| Casdin Capital history | 946.36K | $10.42M | 0.85% | New |
| Vanguard Group history | 666.55K | $7.34M | 0.00% | New |
| Harvard Management Company history | 637.53K | $7.02M | 0.62% | New |
| BlackRock Inc history | 582.59K | $6.41M | 0.00% | New |
| Hillhouse Capital (HHLR Advisors) history | 457.54K | $5.04M | 0.14% | New |
| Geode Capital Management history | 212.46K | $2.34M | 0.00% | New |
| UBS Group AG history | 88.06K | $969.59K | 0.00% | New |
| Charles Schwab Investment Management history | 72.31K | $796.08K | 0.00% | New |
| Northern Trust Corp history | 70.84K | $779.93K | 0.00% | New |
| Morgan Stanley history | 23.89K | $263.06K | 0.00% | New |
| Invesco Ltd history | 20.55K | $226.28K | 0.00% | New |
| Citadel Advisors history | 20.00K | $220.20K | 0.00% | New |
| Marshall Wace history | 19.60K | $215.76K | 0.00% | New |
| BNY Mellon history | 17.23K | $189.74K | 0.00% | New |
| Davidson Kempner Capital Management history | 13.67K | $150.51K | 0.00% | New |
| Goldman Sachs Group history | 13.13K | $144.55K | 0.00% | New |
| JPMorgan Chase & Co history | 10.14K | $111.65K | 0.00% | New |
| Deutsche Bank AG history | 8.88K | $97.82K | 0.00% | New |
| Citigroup Inc history | 6.22K | $68.44K | 0.00% | New |
| Wells Fargo & Co history | 4.69K | $51.67K | 0.00% | New |
| Bank of America Corp history | 4.33K | $47.64K | 0.00% | New |
| Legal & General Investment Management America history | 871 | $9.59K | 0.00% | New |
New Positions (Q2 2026)
- JPMorgan Chase & Co 964.01K sh · $28.00M
- CPP Investments 9.10K sh · $271.54K
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 2.86M sh · $85.28M
- Millennium Management sold 29.89K sh · $892.28K
- Renaissance Technologies sold 15.80K sh · $471.63K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|
| BlackRock Inc | 3.50M | 2.57M | 2.29M | 1.32M | 614.70K | 582.59K |
| Farallon Capital Management | 1.11M | 373.00K | — | — | — | — |
| Fidelity Management & Research (FMR) | 1.06M | 864.21K | 728.61K | 655.61K | 554.53K | 968.38K |
| JPMorgan Chase & Co | 964.01K | — | 20.01K | 7.89K | 4.37K | 10.14K |
| Marshall Wace | 914.57K | 310.64K | 847.47K | 777.70K | 19.60K | 19.60K |
| Citadel Advisors | 874.88K | 809.21K | 448.22K | — | — | 20.00K |
| Geode Capital Management | 858.05K | 599.97K | 527.28K | 473.55K | 231.24K | 212.46K |
| Casdin Capital | 843.86K | 758.86K | 758.86K | 758.86K | 758.86K | 946.36K |
| Hillhouse Capital (HHLR Advisors) | 366.03K | 366.03K | 457.54K | 457.54K | 457.54K | 457.54K |
| Bank of America Corp | 321.23K | 195.08K | 18.38K | 9.57K | 5.78K | 4.33K |
| Northern Trust Corp | 294.74K | 211.38K | 176.26K | 176.89K | 85.55K | 70.84K |
| Goldman Sachs Group | 293.14K | 279.71K | 114.45K | — | — | 13.13K |
| Charles Schwab Investment Management | 260.57K | 186.43K | 175.97K | 167.93K | 75.17K | 72.31K |
| Two Sigma Investments | 192.95K | 15.85K | 7.25K | 11.15K | — | — |
| Morgan Stanley | 135.17K | 204.83K | 258.09K | 212.76K | 31.78K | 23.89K |
| BNY Mellon | 97.59K | 74.27K | 60.44K | 45.24K | 21.55K | 17.23K |
| UBS Group AG | 84.68K | 93.90K | 28.70K | 27.79K | 51.40K | 88.06K |
| Wellington Management Group | 82.72K | 60.59K | 61.20K | — | — | — |
| Franklin Resources | 80.22K | 59.64K | 55.23K | 18.20K | — | — |
| Deutsche Bank AG | 34.99K | 20.26K | 15.52K | 8.88K | 8.88K | 8.88K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details