GPCR — STRUCTURE THERAPEUTICS INC
As of Q2 2026, 25 SEC-registered investment managers reported holding GPCR (STRUCTURE THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $1.32B across 25.50M shares. That is -3.9% by share count (-1.05M shares) versus the previous quarter, while reported value moved +11.8%. Ownership is concentrated: the five largest holders account for 84.9% of reported value and the top ten for 94.7%.
Compared with the prior quarter, 2 opened new positions, 11 added to existing stakes, 9 trimmed, 3 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
GPCR is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
| Fund | Quarter | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | Q2 2026 | 7.81M | $419.18M | 0.02% | Reduce |
| Wellington Management Group history | Q2 2026 | 7.38M | $396.05M | 0.07% | Add |
| Morgan Stanley history | Q2 2026 | 2.81M | $150.63M | 0.01% | Add |
| Principal Global Investors history | Q2 2026 | 1.75M | $94.07M | 0.05% | Hold |
| Casdin Capital history | Q2 2026 | 1.18M | $63.06M | 3.16% | Hold |
| Capital Research Global Investors history | Q1 2025 | 2.16M | $37.46M | 0.01% | Reduce |
| Farallon Capital Management history | Q4 2025 | 454.00K | $31.58M | 0.15% | New |
| Franklin Resources history | Q2 2026 | 578.84K | $31.07M | 0.01% | Add |
| Bank of America Corp history | Q2 2026 | 563.42K | $30.24M | 0.00% | Add |
| BlackRock Inc history | Q2 2026 | 511.15K | $27.43M | 0.00% | Add |
| Goldman Sachs Group history | Q2 2026 | 387.79K | $20.81M | 0.00% | Reduce |
| UBS Group AG history | Q2 2026 | 378.99K | $20.34M | 0.00% | Add |
| Fidelity International (FIL) history | Q1 2025 | 1.15M | $19.91M | 0.02% | Reduce |
| Deutsche Bank AG history | Q2 2026 | 331.87K | $17.81M | 0.01% | Hold |
| Balyasny Asset Management history | Q1 2026 | 304.93K | $14.70M | 0.02% | Add |
| Marshall Wace history | Q2 2026 | 267.59K | $14.36M | 0.01% | Add |
| Capital World Investors history | Q2 2024 | 323.76K | $12.71M | 0.00% | Reduce |
| Point72 Asset Management history | Q3 2025 | 407.70K | $11.42M | 0.02% | Add |
| Two Sigma Investments history | Q2 2026 | 204.16K | $10.96M | 0.01% | Add |
| Janus Henderson Group history | Q1 2026 | 150.82K | $7.27M | 0.00% | Reduce |
New Positions (Q2 2026)
- Northern Trust Corp 5.08K sh · $272.64K
- JPMorgan Chase & Co 3.98K sh · $205.93K
Fully Exited (vs previous quarter)
- Balyasny Asset Management sold 304.93K sh · $14.70M
- Janus Henderson Group sold 150.82K sh · $7.27M
- Renaissance Technologies sold 55.80K sh · $2.69M
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q1 2023 | Q2 2023 | Q3 2023 | Q4 2023 | Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fidelity Management & Research (FMR) | 1.25M | 1.24M | 1.59M | 4.03M | 2.95M | 5.74M | 6.13M | 6.08M | 5.88M | 4.91M | 5.25M | 8.71M | 8.40M | 7.81M |
| Wellington Management Group | 99.90K | 210.27K | 867.58K | 4.37M | 5.83M | 7.55M | 7.77M | 7.79M | 7.79M | 6.88M | 5.69M | 7.12M | 7.26M | 7.38M |
| Morgan Stanley | 11 | — | 23.81K | 287.07K | 293.63K | 132.29K | 162.49K | 387.18K | 692.44K | 917.35K | 577.74K | 2.09M | 2.31M | 2.81M |
| Principal Global Investors | — | — | — | — | — | 165.24K | — | 791.13K | 756.71K | 853.20K | 787.48K | 1.28M | 1.75M | 1.75M |
| Casdin Capital | 677.02K | 997.02K | 1.26M | 1.12M | 1.12M | 700.00K | 700.00K | 700.00K | 700.00K | 1.23M | 1.55M | 1.18M | 1.18M | 1.18M |
| Franklin Resources | 325.00K | 250.81K | 250.82K | 542.32K | 535.75K | 645.71K | 706.11K | 738.09K | 740.15K | 741.78K | 745.73K | 870.58K | 531.60K | 578.84K |
| Bank of America Corp | — | 1.68K | 9.87K | 76.50K | 35.10K | 84.36K | 85.21K | 54.19K | 55.44K | 13.91K | 13.78K | 31.68K | 227.13K | 563.42K |
| BlackRock Inc | — | — | — | — | — | — | 680.10K | 610.59K | 566.50K | 243.33K | 263.94K | 430.08K | 441.98K | 511.15K |
| Goldman Sachs Group | — | — | 71.43K | 427.74K | 448.67K | 682.36K | 726.10K | 582.87K | 359.44K | 220.17K | 504.40K | 397.83K | 434.04K | 387.79K |
| UBS Group AG | — | 2 | — | 59.64K | 82.71K | 5.36K | 39.08K | 280.36K | 247.10K | 184.18K | 229.19K | 202.88K | 212.92K | 378.99K |
| Deutsche Bank AG | — | — | — | — | — | — | — | — | — | — | — | 841.16K | 331.87K | 331.87K |
| Marshall Wace | — | — | 107.52K | 105.77K | 35.24K | 75.93K | 132.68K | 583.21K | 30.63K | 176.06K | — | 168.58K | 69.11K | 267.59K |
| Two Sigma Investments | — | — | — | — | — | — | — | — | — | — | 182.91K | 95.54K | 181.41K | 204.16K |
| Citadel Advisors | 366.29K | 349.66K | 1.08M | 1.22M | 1.42M | 1.57M | 1.56M | 1.66M | 1.15M | 1.50M | 637.30K | 906.62K | 114.40K | 129.00K |
| D. E. Shaw & Co | — | — | — | — | — | — | — | — | 11.66K | 12.16K | 36.35K | 8.62K | 204.79K | 115.30K |
| Geode Capital Management | — | 10.26K | 7.79K | 22.19K | 28.90K | 44.91K | 45.23K | 45.70K | 45.74K | 54.18K | 57.96K | 55.15K | 67.86K | 97.18K |
| Millennium Management | 35.46K | 44.23K | 299.87K | 95.77K | 90.94K | 1.26M | 1.12M | 985.01K | 790.16K | 1.22M | 1.27M | 152.56K | 168.93K | 89.57K |
| Manulife Financial | — | 40.63K | 55.09K | 53.20K | 61.53K | 94.37K | 86.84K | 58.24K | 40.74K | 40.79K | 28.53K | 96.39K | 114.81K | 38.11K |
| Wells Fargo & Co | — | — | — | 726 | 446 | 734 | 3.34K | 10.10K | 7.34K | 7.22K | 6.06K | 5.66K | 7.82K | 10.40K |
| Citigroup Inc | — | — | 125 | 41.68K | 353 | 1.45K | 1.55K | 179.08K | 209.97K | 1.60K | 1.46K | 7.33K | 20.49K | 9.68K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details