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DNLI — DENALI THERAPEUTICS INC

Reported value held$1.99B
Funds holding (latest)45
SectorHealth Care
Funds holding (Q2 2026)34
Institutional value$1.76B · 71.41M sh
New / Add / Cut / Exit1 / 21 / 11 / 3
Top-5 / Top-10 concentration61.1% / 82.3%
Institutional holdings change Accumulating +9.3% (+6.08M sh)
Institutional value change Up +45.5%

As of Q2 2026, 34 SEC-registered investment managers reported holding DNLI (DENALI THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $1.76B across 71.41M shares. That is +9.3% by share count (+6.08M shares) versus the previous quarter, while reported value moved +45.5%. Ownership is concentrated: the five largest holders account for 61.1% of reported value and the top ten for 82.3%.

Compared with the prior quarter, 1 opened new positions, 21 added to existing stakes, 11 trimmed, 3 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

DNLI is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

FundQuarterSharesValuePortfolio WeightChange
BlackRock Inc history Q2 2026 14.03M $360.76M 0.01% Add
Baillie Gifford & Co history Q2 2026 11.96M $307.62M 0.28% Reduce
Vanguard Group history Q4 2025 13.06M $215.59M 0.00% Add
Temasek Holdings history Q2 2026 7.01M $180.37M 0.51% Hold
Fidelity Management & Research (FMR) history Q2 2026 4.54M $116.66M 0.01% Reduce
Goldman Sachs Group history Q2 2026 4.16M $106.89M 0.01% Reduce
Geode Capital Management history Q2 2026 3.97M $102.21M 0.01% Add
UBS Group AG history Q2 2026 3.12M $80.26M 0.01% Add
Norges Bank Investment Management history Q2 2026 2.82M $72.65M 0.01% Reduce
Capital Research Global Investors history Q2 2026 2.57M $65.99M 0.01% Add
Casdin Capital history Q2 2026 2.04M $52.60M 2.63% Add
Principal Global Investors history Q2 2026 1.42M $36.52M 0.02% Reduce
Northern Trust Corp history Q2 2026 1.39M $35.74M 0.00% Add
Charles Schwab Investment Management history Q2 2026 1.24M $32.02M 0.00% Add
Bank of America Corp history Q2 2026 1.23M $31.66M 0.00% Add
Millennium Management history Q2 2026 1.13M $28.95M 0.01% Reduce
Morgan Stanley history Q2 2026 961.05K $24.72M 0.00% Reduce
BNY Mellon history Q2 2026 800.28K $20.58M 0.00% Add
Citadel Advisors history Q2 2026 600.07K $15.43M 0.00% Add
Marshall Wace history Q2 2026 549.83K $14.14M 0.01% Reduce

View all 45 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ3 2021Q4 2021Q1 2022Q2 2022Q3 2022Q4 2022Q1 2023Q2 2023Q3 2023Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
BlackRock Inc — — — — — — — — — — — — 13.79M 13.92M 13.83M 12.05M 12.29M 12.72M 13.03M 14.03M
Baillie Gifford & Co 15.01M 15.06M 14.98M 14.87M 14.72M 15.12M 15.35M 14.84M 14.68M 14.26M 14.04M 13.76M 13.35M 12.31M 12.09M 11.96M 11.59M 12.31M 12.07M 11.96M
Temasek Holdings 5.37M 5.37M 5.37M 5.37M 5.58M 6.52M 6.90M 6.90M 6.90M 6.90M 5.71M 5.71M 5.36M 5.36M 5.36M 5.36M 5.36M 7.01M 7.01M 7.01M
Fidelity Management & Research (FMR) 2.68M 2.95M 2.94M 2.87M 2.45M 2.21M 1.09M 1.08M 1.06M 641.65K 1.23M 234.87K 7.83M 8.02M 7.41M 7.54M 6.34M 6.10M 4.58M 4.54M
Goldman Sachs Group 1.06M 410.76K 406.23K 420.74K 728.27K 771.45K 572.84K 644.91K 407.39K 393.81K 904.36K 1.22M 1.37M 1.06M 1.67M 1.87M 2.16M 3.84M 4.41M 4.16M
Geode Capital Management 1.61M 1.63M 1.63M 1.71M 1.78M 2.05M 2.15M 2.32M 2.53M 2.66M 2.76M 2.98M 2.96M 2.94M 3.04M 3.17M 3.47M 3.46M 3.73M 3.97M
UBS Group AG 64.48K 92.35K 39.11K 6.38K 42.45K 120.18K 127.35K 131.94K 109.70K 290.99K 343.88K 136.22K 141.40K 852.86K 788.43K 950.76K 2.01M 2.40M 2.57M 3.12M
Norges Bank Investment Management — — — — — 1.02M — — — 1.15M — 823.94K — 1.07M — 3.95M — 5.12M — 2.82M
Capital Research Global Investors — — — — 87.77K 2.26M 2.47M 2.84M 2.88M 2.91M 6.05M 7.13M 7.91M 5.48M 4.77M 4.75M 4.76M 3.73M 2.51M 2.57M
Casdin Capital 1.70M 1.50M 1.50M 1.50M 995.00K 1.30M 1.30M 1.30M 1.30M 1.30M 1.30M 1.30M 990.00K 990.00K 990.00K 890.00K 890.00K 1.84M 1.84M 2.04M
Principal Global Investors 303.83K 330.27K 269.00K 267.73K 545.87K 526.46K 488.96K 686.49K 680.08K 1.07M 1.12M 1.09M 1.24M 1.13M 1.08M 1.07M 1.27M 1.52M 1.48M 1.42M
Northern Trust Corp 951.73K 959.09K 906.23K 890.62K 889.97K 984.19K 1.02M 1.09M 1.12M 1.10M 1.09M 1.08M 1.09M 1.20M 1.13M 1.20M 1.23M 1.20M 1.31M 1.39M
Charles Schwab Investment Management 703.75K 717.19K 704.25K 731.52K 730.88K 836.67K 836.33K 867.63K 981.06K 1.01M 1.04M 1.06M 1.02M 1.03M 1.01M 1.06M 1.15M 1.20M 1.21M 1.24M
Bank of America Corp 77.85K 128.95K 241.24K 119.07K 220.22K 334.77K 419.84K 270.25K 295.79K 458.64K 851.98K 742.05K 348.16K 270.33K 447.76K 650.22K 961.14K 932.14K 1.13M 1.23M
Millennium Management 41.84K 18.36K — 645.34K 496.18K 297.09K 386.29K 478.19K 118.35K — 390.62K 619.93K 60.17K 404.22K 1.49M 900.50K 1.31M 369.77K 1.27M 1.13M
Morgan Stanley 383.99K 287.26K 705.65K 423.01K 681.33K 432.49K 569.12K 1.08M 981.57K 977.49K 928.13K 1.22M 1.74M 1.23M 1.25M 1.31M 1.69M 1.22M 1.10M 961.05K
BNY Mellon 376.72K 932.59K 1.61M 1.87M 1.90M 2.01M 2.02M 1.99M 1.96M 1.87M 1.78M 1.54M 1.33M 1.24M 1.10M 790.76K 800.75K 762.09K 768.04K 800.28K
Citadel Advisors 103.71K 538.28K 761.20K 332.40K 86.54K 69.21K 1.41M 67.40K 76.11K 77.21K 1.39M 1.24M 796.38K 856.11K 1.20M 1.28M 699.82K 806.25K 351.02K 600.07K
Marshall Wace 531.36K 383.94K 152.85K 817.65K 675.87K 960.64K 350.54K — — 1.67M 2.15M 2.42M 1.97M 1.79M 2.19M 1.41M 787.03K 763.89K 991.27K 549.83K
Citigroup Inc 109.03K 120.38K 35.38K 111.81K 192.64K 128.12K 208.34K 108.03K 138.31K 141.28K 382.42K 104.45K 94.71K 166.71K 194.00K 76.31K 14.94K 30.95K 99.28K 487.28K

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