ZYME — ZYMEWORKS INC
As of Q2 2026, 30 SEC-registered investment managers reported holding ZYME (ZYMEWORKS INC) in their latest 13F filings, with a combined reported value of $323.58M across 12.43M shares. That is -14.5% by share count (-2.11M shares) versus the previous quarter, while reported value moved -10.9%. Ownership is concentrated: the five largest holders account for 71.4% of reported value and the top ten for 86.2%.
Compared with the prior quarter, 2 opened new positions, 11 added to existing stakes, 16 trimmed, 5 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
ZYME is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
| Fund | Quarter | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|---|
| BlackRock Inc history | Q2 2026 | 4.25M | $111.12M | 0.00% | Reduce |
| Vanguard Group history | Q4 2025 | 2.33M | $61.32M | 0.00% | Add |
| Morgan Stanley history | Q2 2026 | 2.23M | $58.33M | 0.00% | Reduce |
| Lone Pine Capital history | Q3 2021 | 976.74K | $28.36M | 0.10% | New |
| Citadel Advisors history | Q2 2026 | 966.34K | $25.26M | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | Q2 2026 | 702.57K | $18.37M | 0.00% | Add |
| Geode Capital Management history | Q2 2026 | 692.41K | $18.10M | 0.00% | Add |
| Goldman Sachs Group history | Q2 2026 | 470.82K | $12.31M | 0.00% | Reduce |
| Arrowstreet Capital history | Q2 2026 | 418.50K | $10.94M | 0.01% | Reduce |
| Deutsche Bank AG history | Q2 2026 | 397.19K | $10.38M | 0.00% | Reduce |
| Northern Trust Corp history | Q2 2026 | 321.07K | $8.39M | 0.00% | Hold |
| Royce & Associates history | Q1 2026 | 299.20K | $7.49M | 0.07% | New |
| Renaissance Technologies history | Q4 2025 | 220.88K | $5.82M | 0.01% | Reduce |
| Bank of America Corp history | Q2 2026 | 219.07K | $5.73M | 0.00% | Reduce |
| Wells Fargo & Co history | Q2 2026 | 217.20K | $5.68M | 0.00% | Add |
| Point72 Asset Management history | Q4 2024 | 330.13K | $4.83M | 0.01% | Add |
| Farallon Capital Management history | Q1 2025 | 400.00K | $4.76M | 0.03% | Reduce |
| Charles Schwab Investment Management history | Q2 2026 | 152.42K | $3.98M | 0.00% | Reduce |
| D. E. Shaw & Co history | Q2 2026 | 144.81K | $3.79M | 0.00% | Reduce |
| Citigroup Inc history | Q2 2026 | 131.44K | $3.44M | 0.00% | Add |
New Positions (Q2 2026)
- JPMorgan Chase & Co 106.40K sh · $2.56M
- Two Sigma Investments 71.87K sh · $1.88M
Fully Exited (vs previous quarter)
- Royce & Associates sold 299.20K sh · $7.49M
- Millennium Management sold 50.00K sh · $1.25M
- Janus Henderson Group sold 18.20K sh · $455.82K
- Amundi US sold 14.08K sh · $352.66K
- Lazard Asset Management sold 10.60K sh · $265.47K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q3 2021 | Q4 2021 | Q1 2022 | Q2 2022 | Q3 2022 | Q4 2022 | Q1 2023 | Q2 2023 | Q3 2023 | Q4 2023 | Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | — | — | — | — | — | — | — | — | — | — | — | — | 4.26M | 4.18M | 4.09M | 3.79M | 3.99M | 4.60M | 4.55M | 4.25M |
| Morgan Stanley | 2.30M | 2.11M | 2.33M | 1.96M | 5.26M | 5.57M | 5.56M | 5.49M | 4.48M | 4.86M | 5.11M | 4.24M | 5.11M | 4.20M | 4.07M | 4.18M | 3.98M | 2.59M | 2.48M | 2.23M |
| Citadel Advisors | 66.79K | 90.12K | 409.00K | 270.12K | 211.93K | 73.67K | 96.98K | 101.52K | 76.31K | 205.27K | 1.10M | 621.18K | 51.51K | 75.26K | 245.37K | 310.45K | 251.76K | 300.25K | 1.25M | 966.34K |
| Fidelity Management & Research (FMR) | 3.48M | 3.49M | 547.08K | — | — | — | — | 24.70K | 24.71K | 25.59K | 25.74K | 1.81K | 3.34K | 21.97K | 12.83K | 3.11K | 3.51K | 560.09K | 667.15K | 702.57K |
| Geode Capital Management | — | — | — | — | — | — | 31.50K | 561.93K | 599.46K | 639.67K | 668.98K | 712.95K | 713.91K | 689.88K | 705.03K | 705.36K | 678.64K | 647.97K | 659.94K | 692.41K |
| Goldman Sachs Group | 278.21K | 2.52M | 520.44K | 1.18M | — | 125.06K | 328.08K | 190.88K | 168.57K | 200.62K | 270.55K | 173.60K | 251.48K | 249.96K | 200.05K | 428.86K | 443.52K | 420.21K | 599.49K | 470.82K |
| Arrowstreet Capital | — | — | — | — | — | — | — | 542.23K | 472.00K | 367.02K | 581.56K | — | 407.77K | — | — | — | 313.75K | 700.00K | 743.90K | 418.50K |
| Deutsche Bank AG | 93.64K | 125.52K | 126.76K | 91.66K | 91.66K | 715.44K | 583.53K | 605.13K | 114.85K | 888.63K | 889.25K | 2.36M | 1.53M | 1.55M | 1.55M | 1.54M | 1.54M | 1.60M | 921.25K | 397.19K |
| Northern Trust Corp | 46.48K | 46.43K | 45.80K | 12.12K | 14.23K | 12.83K | 30.08K | 421.03K | 419.87K | 417.15K | 418.25K | 364.41K | 370.93K | 394.83K | 386.92K | 349.80K | 348.25K | 307.98K | 320.21K | 321.07K |
| Bank of America Corp | 27.61K | 2.66M | 4.71K | 103.86K | 2.79K | 28.11K | 108.36K | 76.75K | 89.70K | 94.64K | 53.31K | 92.02K | 69.73K | 31.70K | 62.13K | 90.38K | 175.33K | 89.52K | 236.75K | 219.07K |
| Wells Fargo & Co | 79.74K | 26.47K | 81.71K | 100.41K | 108.93K | 101.33K | 84.87K | 206.39K | 191.63K | 238.25K | 238.69K | 170.07K | 177.41K | 164.06K | 100.31K | 166.43K | 176.63K | 208.31K | 189.64K | 217.20K |
| Charles Schwab Investment Management | — | — | — | — | — | — | — | 122.03K | 121.87K | 125.49K | 125.49K | 132.15K | 132.80K | 131.31K | 133.64K | 124.20K | 193.36K | 220.91K | 185.12K | 152.42K |
| D. E. Shaw & Co | 8.25K | 32.08K | 437.49K | 21.91K | 88.48K | 369.19K | — | 49.35K | 65.07K | — | 27.11K | 43.76K | 21.78K | 20.84K | 63.10K | 255.29K | 126.92K | 223.79K | 235.62K | 144.81K |
| Citigroup Inc | 732 | 810 | 1.48K | 613 | 48 | 25.86K | 75.45K | 86.02K | 60.01K | 25.97K | 20.71K | 54.71K | 79.89K | 83.14K | 41.20K | 156.00K | 117.80K | 111.21K | 114.33K | 131.44K |
| BNY Mellon | 13.89K | — | — | — | — | — | — | 137.10K | 139.41K | 276.90K | 294.88K | 309.70K | 249.99K | 120.68K | 120.73K | 133.09K | 137.55K | 128.13K | 124.11K | 131.11K |
| UBS Group AG | 350 | 3.60K | 25 | 25 | 25 | 25 | 15.07K | 30.39K | 37.82K | 64.41K | 67.42K | 125.67K | 135.56K | 166.90K | 214.30K | 251.51K | 51.84K | 278.85K | 171.78K | 115.09K |
| Invesco Ltd | 9.87K | — | 46.54K | 54.29K | 51.44K | 51.18K | — | 36.29K | 114.68K | 57.09K | 231.18K | 67.74K | 163.04K | 69.38K | 78.21K | 89.37K | 93.66K | 257.58K | 125.63K | 112.21K |
| AQR Capital Management | — | — | 12.45K | — | — | — | — | 469.47K | 799.68K | 686.19K | 489.50K | 94.27K | 24.86K | 26.07K | 48.48K | 166.14K | 152.63K | 91.08K | 90.67K | 111.28K |
| Wellington Management Group | 599.13K | 2.86M | 1.18M | — | — | — | — | 56.38K | 156.68K | 205.25K | 286.60K | 334.78K | 243.19K | 219.10K | 182.25K | 180.69K | 168.69K | 181.71K | 138.69K | 110.01K |
| JPMorgan Chase & Co | 30.98K | 75.89K | 686.78K | 11 | 11 | 11 | 333 | 41.57K | 36.40K | 49.68K | 36.58K | 39.47K | 39.28K | 111.98K | 38.41K | 441.69K | 33.88K | 35.01K | — | 106.40K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details