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XENE — XENON PHARMACEUTICALS INC

Reported value held$2.35B
Funds holding (latest)40
SectorHealth Care
Funds holding (Q2 2026)37
Institutional value$2.08B · 37.65M sh
New / Add / Cut / Exit3 / 21 / 9 / 1
Top-5 / Top-10 concentration66.5% / 83.9%
Institutional holdings change Accumulating +0.2% (+61.80K sh)
Institutional value change Down -1.5%

As of Q2 2026, 37 SEC-registered investment managers reported holding XENE (XENON PHARMACEUTICALS INC) in their latest 13F filings, with a combined reported value of $2.08B across 37.65M shares. That is +0.2% by share count (+61.80K shares) versus the previous quarter, while reported value moved -1.5%. Ownership is concentrated: the five largest holders account for 66.5% of reported value and the top ten for 83.9%.

Compared with the prior quarter, 3 opened new positions, 21 added to existing stakes, 9 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

XENE is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 37 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 9.65M $582.35M 0.03% Reduce
BlackRock Inc history 7.52M $454.06M 0.01% Add
JPMorgan Chase & Co history 2.62M $157.38M 0.02% New
Two Sigma Investments history 1.64M $99.16M 0.08% Add
Citadel Advisors history 1.45M $87.41M 0.01% Reduce
Franklin Resources history 1.44M $86.78M 0.02% Add
Wellington Management Group history 1.43M $86.04M 0.02% Reduce
Geode Capital Management history 1.37M $82.69M 0.00% Add
Invesco Ltd history 903.46K $54.53M 0.01% Add
Capital World Investors history 862.77K $52.08M 0.01% Add
Goldman Sachs Group history 773.62K $46.70M 0.00% Hold
Marshall Wace history 689.34K $41.61M 0.03% New
Northern Trust Corp history 671.57K $40.54M 0.01% Add
BNY Mellon history 421.52K $25.44M 0.00% Add
Morgan Stanley history 406.26K $24.52M 0.00% Reduce
Bank of America Corp history 404.07K $24.39M 0.00% Add
Millennium Management history 376.78K $22.74M 0.01% Add
Charles Schwab Investment Management history 249.47K $15.06M 0.00% Add
D. E. Shaw & Co history 223.92K $13.52M 0.01% Add
Balyasny Asset Management history 193.41K $11.67M 0.01% Reduce
Deutsche Bank AG history 191.13K $11.54M 0.00% Add
Renaissance Technologies history 187.11K $11.29M 0.02% Reduce
Wells Fargo & Co history 173.94K $10.50M 0.00% Add
Point72 Asset Management history 130.38K $7.87M 0.01% Add
Citigroup Inc history 92.12K $5.56M 0.00% Add
Legal & General Investment Management America history 73.73K $4.45M 0.00% Hold
Royce & Associates history 65.03K $3.93M 0.03% New
Lazard Asset Management history 44.12K $2.66M 0.00% Reduce
Prudential Financial history 39.40K $2.38M 0.00% Add
Manulife Financial history 28.93K $1.75M 0.00% Add
UBS Group AG history 28.25K $1.71M 0.00% Reduce
Baron Funds history 25.00K $1.51M 0.00% Hold
Amundi US history 10.72K $647.00K 0.00% Reduce
PNC Financial Services history 8.70K $525.19K 0.00% Add
Principal Global Investors history 7.51K $453.06K 0.00% Add
AQR Capital Management history 7.26K $438.39K 0.00% Hold
T. Rowe Price Associates history 3.25M $196.06K 0.02% Add

Q1 2026 — 35 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 10.82M $629.10M 0.03% Add
BlackRock Inc history 5.64M $327.97M 0.01% Add
Wellington Management Group history 4.83M $280.84M 0.05% Add
Janus Henderson Group history 4.18M $242.86M 0.12% Add
Citadel Advisors history 2.89M $167.84M 0.03% Add
Franklin Resources history 1.28M $74.47M 0.02% Add
Geode Capital Management history 1.09M $63.55M 0.00% Add
Capital World Investors history 840.07K $48.85M 0.01% Add
Goldman Sachs Group history 769.88K $44.77M 0.01% Add
Two Sigma Investments history 606.09K $35.24M 0.03% Add
Northern Trust Corp history 527.78K $30.69M 0.00% Add
Morgan Stanley history 473.76K $27.55M 0.00% Add
BNY Mellon history 396.14K $23.04M 0.00% Add
Renaissance Technologies history 300.50K $17.47M 0.03% New
Bank of America Corp history 265.27K $15.43M 0.00% Add
Balyasny Asset Management history 233.91K $13.60M 0.02% Add
Millennium Management history 201.78K $11.73M 0.01% Reduce
Charles Schwab Investment Management history 189.08K $11.00M 0.00% Hold
Deutsche Bank AG history 162.68K $9.46M 0.00% Reduce
Wells Fargo & Co history 115.65K $6.73M 0.00% Reduce
UBS Group AG history 99.62K $5.79M 0.00% Add
Legal & General Investment Management America history 73.49K $4.27M 0.00% Add
Invesco Ltd history 59.10K $3.44M 0.00% Add
Lazard Asset Management history 50.76K $2.95M 0.01% Reduce
D. E. Shaw & Co history 38.74K $2.25M 0.00% Add
Baron Funds history 25.00K $1.45M 0.00% Reduce
Manulife Financial history 21.68K $1.26M 0.00% Reduce
Point72 Asset Management history 18.60K $1.08M 0.00% Hold
Amundi US history 18.01K $1.05M 0.00% Add
Prudential Financial history 13.01K $756.53K 0.00% New
Citigroup Inc history 12.15K $706.58K 0.00% Add
PNC Financial Services history 8.10K $470.84K 0.00% Add
AQR Capital Management history 7.28K $423.27K 0.00% New
Principal Global Investors history 6.24K $363.09K 0.00% Add
T. Rowe Price Associates history 1.33M $77.32K 0.01% Add

Q4 2025 — 36 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 8.92M $399.81M 0.02% Hold
BlackRock Inc history 5.10M $228.59M 0.00% Add
Wellington Management Group history 4.76M $213.56M 0.04% Add
Janus Henderson Group history 4.08M $183.11M 0.08% Add
JPMorgan Chase & Co history 1.49M $66.96M 0.01% Add
Citadel Advisors history 1.43M $64.08M 0.01% Add
Geode Capital Management history 952.68K $42.69M 0.00% Reduce
Franklin Resources history 758.06K $33.98M 0.01% Add
Goldman Sachs Group history 696.05K $31.20M 0.00% Reduce
Vanguard Group history 664.64K $29.79M 0.00% Reduce
Capital World Investors history 655.74K $29.39M 0.00% Hold
Millennium Management history 635.06K $28.46M 0.01% Reduce
Northern Trust Corp history 438.71K $19.66M 0.00% Reduce
Two Sigma Investments history 436.74K $19.57M 0.03% New
BNY Mellon history 387.16K $17.35M 0.00% Reduce
Morgan Stanley history 294.33K $13.19M 0.00% Reduce
Bank of America Corp history 221.37K $9.92M 0.00% Add
Deutsche Bank AG history 190.23K $8.53M 0.00% Add
Charles Schwab Investment Management history 189.06K $8.47M 0.00% Hold
Marshall Wace history 162.55K $7.29M 0.01% Reduce
Wells Fargo & Co history 152.30K $6.83M 0.00% Add
Moore Capital Management history 140.00K $6.27M 0.09% Hold
Balyasny Asset Management history 84.36K $3.78M 0.01% Reduce
Lazard Asset Management history 78.66K $3.53M 0.01% New
Legal & General Investment Management America history 70.27K $3.15M 0.00% Reduce
UBS Group AG history 52.54K $2.35M 0.00% Reduce
Invesco Ltd history 50.95K $2.28M 0.00% Reduce
Manulife Financial history 32.62K $1.45M 0.00% Add
D. E. Shaw & Co history 30.85K $1.38M 0.00% Reduce
Baron Funds history 30.00K $1.34M 0.00% Hold
Point72 Asset Management history 18.60K $833.65K 0.00% New
Citigroup Inc history 7.36K $329.92K 0.00% Reduce
PNC Financial Services history 6.57K $294.65K 0.00% Add
Amundi US history 4.61K $206.57K 0.00% New
Principal Global Investors history 4.49K $201.15K 0.00% Reduce
T. Rowe Price Associates history 862.30K $38.65K 0.00% Add

Q3 2025 — 34 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 8.92M $358.09M 0.02% Hold
BlackRock Inc history 4.77M $191.55M 0.00% Reduce
Janus Henderson Group history 3.94M $158.31M 0.07% Add
Wellington Management Group history 3.61M $144.94M 0.03% Add
Millennium Management history 1.45M $58.18M 0.03% Add
JPMorgan Chase & Co history 1.40M $56.17M 0.01% Add
Citadel Advisors history 1.01M $40.58M 0.01% Add
Geode Capital Management history 977.43K $39.24M 0.00% Add
Vanguard Group history 851.39K $34.18M 0.00% Reduce
Goldman Sachs Group history 720.66K $28.93M 0.00% Add
Franklin Resources history 695.90K $27.94M 0.01% Add
Capital World Investors history 655.74K $26.33M 0.00% Hold
Marshall Wace history 611.98K $24.57M 0.03% Reduce
Northern Trust Corp history 498.15K $20.00M 0.00% Add
BNY Mellon history 418.42K $16.80M 0.00% Reduce
Morgan Stanley history 366.57K $14.72M 0.00% Reduce
Balyasny Asset Management history 322.46K $12.95M 0.02% Add
Bank of America Corp history 199.11K $7.99M 0.00% Reduce
Charles Schwab Investment Management history 188.75K $7.58M 0.00% Reduce
Moore Capital Management history 140.00K $5.62M 0.08% Add
Wells Fargo & Co history 115.22K $4.63M 0.00% Add
Deutsche Bank AG history 112.95K $4.53M 0.00% Add
UBS Group AG history 106.74K $4.29M 0.00% Reduce
Legal & General Investment Management America history 79.85K $3.21M 0.00% Reduce
Invesco Ltd history 56.06K $2.25M 0.00% Reduce
D. E. Shaw & Co history 48.45K $1.95M 0.00% Reduce
Baron Funds history 30.00K $1.20M 0.00% Reduce
Manulife Financial history 23.93K $960.87K 0.00% Reduce
Citigroup Inc history 14.87K $597.03K 0.00% Reduce
Prudential Financial history 8.85K $355.33K 0.00% Reduce
PNC Financial Services history 5.90K $236.84K 0.00% Add
Principal Global Investors history 5.82K $233.59K 0.00% New
Renaissance Technologies history 5.20K $208.78K 0.00% Reduce
T. Rowe Price Associates history 41.69K $1.68K 0.00% Add

Q2 2025 — 41 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 8.88M $278.08M 0.02% Add
Fidelity Management & Research (FMR) history 8.88M $278.08M 0.02% Add
BlackRock Inc history 5.37M $167.93M 0.00% Add
BlackRock Inc history 5.37M $167.93M 0.00% Add
Janus Henderson Group history 3.58M $112.01M 0.06% Add
Wellington Management Group history 2.17M $68.07M 0.01% Reduce
JPMorgan Chase & Co history 1.26M $39.33M 0.01% Reduce
JPMorgan Chase & Co history 1.26M $39.33M 0.01% Reduce
Marshall Wace history 1.02M $31.93M 0.04% Add
Geode Capital Management history 970.34K $30.37M 0.00% Add
Millennium Management history 882.84K $27.63M 0.01% Add
Vanguard Group history 873.23K $27.33M 0.00% Add
Franklin Resources history 666.47K $20.86M 0.01% Add
Capital World Investors history 655.74K $20.52M 0.00% Reduce
Goldman Sachs Group history 561.80K $17.58M 0.00% Add
Goldman Sachs Group history 561.80K $17.58M 0.00% Add
Northern Trust Corp history 489.94K $15.34M 0.00% Add
BNY Mellon history 436.02K $13.65M 0.00% Add
Morgan Stanley history 387.60K $12.13M 0.00% Add
Morgan Stanley history 387.60K $12.13M 0.00% Add
Bank of America Corp history 358.43K $11.22M 0.00% Add
Charles Schwab Investment Management history 192.24K $6.02M 0.00% New
Citadel Advisors history 178.04K $5.57M 0.00% Reduce
Citadel Advisors history 178.04K $5.57M 0.00% Reduce
UBS Group AG history 153.06K $4.79M 0.00% Add
D. E. Shaw & Co history 141.78K $4.44M 0.00% Reduce
Wells Fargo & Co history 112.56K $3.52M 0.00% Add
Deutsche Bank AG history 104.53K $3.27M 0.00% Add
Deutsche Bank AG history 104.53K $3.27M 0.00% Add
Moore Capital Management history 90.00K $2.82M 0.04% Add
Legal & General Investment Management America history 81.79K $2.56M 0.00% Add
Balyasny Asset Management history 68.87K $2.16M 0.00% Reduce
Invesco Ltd history 59.60K $1.87M 0.00% Reduce
Baron Funds history 56.00K $1.75M 0.01% Reduce
Prudential Financial history 47.76K $1.53M 0.00% Add
Citigroup Inc history 36.29K $1.14M 0.00% Add
Manulife Financial history 26.08K $816.27K 0.00% New
Renaissance Technologies history 8.60K $269.18K 0.00% Reduce
Renaissance Technologies history 8.60K $269.18K 0.00% Reduce
PNC Financial Services history 3.46K $108.36K 0.00% Reduce
T. Rowe Price Associates history 37.94K $1.19K 0.00% New

Q1 2025 — 43 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 8.29M $278.05M 0.02% Add
Fidelity Management & Research (FMR) history 8.29M $278.05M 0.02% Add
Wellington Management Group history 3.79M $127.13M 0.03% Hold
Janus Henderson Group history 3.33M $113.91M 0.06% Add
Capital World Investors history 2.22M $74.64M 0.01% Reduce
BlackRock Inc history 2.04M $68.31M 0.00% Reduce
BlackRock Inc history 2.04M $68.31M 0.00% Reduce
JPMorgan Chase & Co history 1.36M $45.55M 0.01% Hold
JPMorgan Chase & Co history 1.36M $45.55M 0.01% Hold
Marshall Wace history 758.14K $25.44M 0.03% Reduce
Citadel Advisors history 701.29K $23.53M 0.00% Add
Citadel Advisors history 701.29K $23.53M 0.00% Add
Franklin Resources history 491.12K $16.48M 0.01% Reduce
Goldman Sachs Group history 442.73K $14.85M 0.00% Add
Goldman Sachs Group history 442.73K $14.85M 0.00% Add
Vanguard Group history 336.51K $11.29M 0.00% Reduce
Balyasny Asset Management history 267.14K $8.96M 0.01% Add
BNY Mellon history 251.15K $8.43M 0.00% Add
Two Sigma Investments history 236.98K $7.95M 0.02% Reduce
Two Sigma Investments history 236.98K $7.95M 0.02% Reduce
Millennium Management history 234.06K $7.85M 0.00% Reduce
Point72 Asset Management history 209.76K $7.04M 0.02% New
Point72 Asset Management history 209.76K $7.04M 0.02% New
Invesco Ltd history 205.76K $6.90M 0.00% Reduce
Renaissance Technologies history 154.70K $5.19M 0.01% Add
Renaissance Technologies history 154.70K $5.19M 0.01% Add
D. E. Shaw & Co history 152.19K $5.11M 0.01% Add
Bank of America Corp history 136.57K $4.58M 0.00% Add
Morgan Stanley history 129.49K $4.34M 0.00% Add
Morgan Stanley history 129.49K $4.34M 0.00% Add
UBS Group AG history 105.33K $3.53M 0.00% Add
Baron Funds history 100.10K $3.36M 0.01% Hold
Northern Trust Corp history 81.02K $2.72M 0.00% Add
Geode Capital Management history 69.60K $2.33M 0.00% Hold
Wells Fargo & Co history 65.91K $2.21M 0.00% Add
Legal & General Investment Management America history 60.41K $2.03M 0.00% Hold
Moore Capital Management history 55.00K $1.85M 0.04% Hold
Deutsche Bank AG history 53.71K $1.80M 0.00% Hold
Deutsche Bank AG history 53.71K $1.80M 0.00% Hold
Prudential Financial history 39.00K $1.31M 0.00% Hold
Citigroup Inc history 7.03K $235.82K 0.00% Add
PNC Financial Services history 5.22K $175.13K 0.00% Add
Amundi US history 114 $3.50K 0.00% Add

View all 40 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021
Fidelity Management & Research (FMR) 9.65M 10.82M 8.92M 8.92M 8.88M 8.29M 7.53M 6.92M 6.77M 6.60M 5.66M 4.25M 5.19M 4.73M 4.69M 4.67M 4.57M 3.83M 3.91M 3.06M
BlackRock Inc 7.52M 5.64M 5.10M 4.77M 5.37M 2.04M 2.11M 2.11M — — — — — — — — — — — —
JPMorgan Chase & Co 2.62M — 1.49M 1.40M 1.26M 1.36M 1.36M 976.78K 71.65K 36.62K 30.00K 50.30K 79.22K 32.79K 2.09K 4.27K 2.45K 6.37K 4.78K 3.01K
Two Sigma Investments 1.64M 606.09K 436.74K — — 236.98K 273.35K 243.58K 195.13K 274.63K 340.01K 80.63K 18.63K 11.45K — 55.97K — 232.65K 278.34K 169.68K
Citadel Advisors 1.45M 2.89M 1.43M 1.01M 178.04K 701.29K 344.10K 742.90K 807.73K 1.31M 1.44M 765.02K 518.91K 917.33K 1.21M 1.18M 1.67M 1.46M 1.34M 1.19M
Franklin Resources 1.44M 1.28M 758.06K 695.90K 666.47K 491.12K 575.59K 565.91K 578.87K 542.29K 293.82K 172.61K 172.61K 172.61K — — — — — —
Wellington Management Group 1.43M 4.83M 4.76M 3.61M 2.17M 3.79M 3.78M 3.84M 3.83M 3.92M 4.16M 1.73M 1.05M 247.44K — — — — — —
Geode Capital Management 1.37M 1.09M 952.68K 977.43K 970.34K 69.60K 69.53K 68.81K 68.93K 64.23K 62.07K 55.95K 55.91K 55.73K 55.28K 61.82K 45.52K 28.20K 28.20K 21.65K
Invesco Ltd 903.46K 59.10K 50.95K 56.06K 59.60K 205.76K 209.55K 215.82K 866.78K 1.05M 719.72K 716.30K 699.99K 16.47K — — — 198.70K 294.10K —
Capital World Investors 862.77K 840.07K 655.74K 655.74K 655.74K 2.22M 2.29M 2.68M 2.68M 2.68M 2.68M 2.27M 2.27M 2.27M 2.27M 2.27M 2.27M 2.27M 2.27M 963.50K
Goldman Sachs Group 773.62K 769.88K 696.05K 720.66K 561.80K 442.73K 410.25K 459.62K 364.17K 299.77K 376.30K 255.37K 275.08K 285.42K 283.54K 465.26K 296.31K 724.34K 171.39K 95.98K
Marshall Wace 689.34K — 162.55K 611.98K 1.02M 758.14K 899.72K 1.20M 1.38M 1.45M 1.53M 2.15M 2.32M 2.32M 2.37M 2.81M 1.99M 1.53M 1.22M 29.80K
Northern Trust Corp 671.57K 527.78K 438.71K 498.15K 489.94K 81.02K 65.78K 43.41K 46.85K 48.47K 61.97K 69.17K 65.48K 61.00K 60.22K 50.89K 48.00K 44.78K 50.60K 37.85K
BNY Mellon 421.52K 396.14K 387.16K 418.42K 436.02K 251.15K 46.60K 48.89K 51.25K 66.91K 66.66K 167.35K 211.74K 199.39K 388.36K 437.64K 563.19K 579.21K 791.52K 934.64K
Morgan Stanley 406.26K 473.76K 294.33K 366.57K 387.60K 129.49K 68.06K 239.94K 238.77K 386.20K 225.15K 243.15K 205.54K 242.98K 88.13K 158.45K 998.07K 1.44M 872.08K 40.74K
Bank of America Corp 404.07K 265.27K 221.37K 199.11K 358.43K 136.57K 106.91K 127.46K 142.33K 157.10K 250.31K 123.97K 159.38K 134.11K 88.75K 27.00K 36.66K 6.28K 42.80K 14.39K
Millennium Management 376.78K 201.78K 635.06K 1.45M 882.84K 234.06K 346.04K 209.03K 175.58K 83.66K 76.97K 150.49K 213.34K 221.47K 594.54K 560.35K 492.69K 136.33K 90.62K 296.22K
Charles Schwab Investment Management 249.47K 189.08K 189.06K 188.75K 192.24K — — — — — — — — — — — — — — —
D. E. Shaw & Co 223.92K 38.74K 30.85K 48.45K 141.78K 152.19K 86.97K 204.89K 161.72K 198.53K 84.15K 40.55K 98.75K 206.67K 360.42K 409.56K 326.54K 330.53K 475.14K 148.88K
Balyasny Asset Management 193.41K 233.91K 84.36K 322.46K 68.87K 267.14K 184.58K 84.20K 233.34K 201.27K 15.85K — — — 162.83K 147.35K — — — —

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