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VYNE — VYNE THERAPEUTICS INC

Reported value held$1.51M
Funds holding (latest)23
Sector—
Funds holding (Q2 2026)10
Institutional value$869.08K · 1.34M sh
New / Add / Cut / Exit1 / 3 / 3 / 0
Top-5 / Top-10 concentration95.0% / 100.0%
Institutional holdings change Reducing -12.6% (-192.70K sh)
Institutional value change Down -4.8%

As of Q2 2026, 10 SEC-registered investment managers reported holding VYNE (VYNE THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $869.08K across 1.34M shares. That is -12.6% by share count (-192.70K shares) versus the previous quarter, while reported value moved -4.8%. Ownership is concentrated: the five largest holders account for 95.0% of reported value and the top ten for 100.0%.

Compared with the prior quarter, 1 opened new positions, 3 added to existing stakes, 3 trimmed. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 10 funds

FundSharesValuePortfolio WeightChange
Citadel Advisors history 468.46K $304.82K 0.00% Reduce
Two Sigma Investments history 438.82K $285.54K 0.00% Add
Geode Capital Management history 258.20K $168.02K 0.00% Reduce
UBS Group AG history 58.60K $38.15K 0.00% Reduce
BlackRock Inc history 44.41K $28.89K 0.00% Hold
Northern Trust Corp history 43.68K $28.42K 0.00% Add
Renaissance Technologies history 23.30K $15.16K 0.00% Add
Wells Fargo & Co history 65 $42 0.00% Hold
Morgan Stanley history 43 $28 0.00% Hold
JPMorgan Chase & Co history 8 $5 0.00% New

Q1 2026 — 9 funds

FundSharesValuePortfolio WeightChange
Citadel Advisors history 514.44K $307.38K 0.00% Add
Two Sigma Investments history 426.41K $254.78K 0.00% Add
Geode Capital Management history 322.71K $192.82K 0.00% Add
UBS Group AG history 179.78K $107.51K 0.00% Add
BlackRock Inc history 44.41K $26.53K 0.00% Hold
Northern Trust Corp history 23.11K $13.81K 0.00% Hold
Renaissance Technologies history 17.30K $10.34K 0.00% New
Wells Fargo & Co history 65 $39 0.00% Hold
Morgan Stanley history 43 $26 0.00% Hold

Q4 2025 — 11 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 314.55K $182.44K 0.00% Add
Geode Capital Management history 225.15K $130.61K 0.00% Add
Two Sigma Investments history 220.00K $127.62K 0.00% Hold
UBS Group AG history 62.76K $36.40K 0.00% Add
BlackRock Inc history 44.41K $25.76K 0.00% Hold
Citadel Advisors history 30.53K $17.71K 0.00% New
Northern Trust Corp history 23.11K $13.41K 0.00% Hold
Bank of America Corp history 1.68K $973 0.00% Add
JPMorgan Chase & Co history 146 $85 0.00% Hold
Wells Fargo & Co history 65 $38 0.00% Hold
Morgan Stanley history 43 $25 0.00% Reduce

Q3 2025 — 10 funds

FundSharesValuePortfolio WeightChange
Two Sigma Investments history 220.79K $73.96K 0.00% New
Vanguard Group history 190.38K $63.78K 0.00% Reduce
Geode Capital Management history 137.12K $45.94K 0.00% Add
BlackRock Inc history 44.41K $14.88K 0.00% Hold
Northern Trust Corp history 23.11K $7.74K 0.00% Hold
UBS Group AG history 5.57K $1.87K 0.00% New
Bank of America Corp history 1.53K $513 0.00% Add
Morgan Stanley history 911 $305 0.00% Reduce
JPMorgan Chase & Co history 146 $49 0.00% Hold
Wells Fargo & Co history 65 $22 0.00% Hold

Q2 2025 — 10 funds

FundSharesValuePortfolio WeightChange
Citadel Advisors history 1.04M $1.72M 0.00% Reduce
Vanguard Group history 496.30K $818.89K 0.00% Add
Geode Capital Management history 133.33K $220.00K 0.00% Hold
BlackRock Inc history 44.41K $73.27K 0.00% Reduce
Northern Trust Corp history 23.11K $38.13K 0.00% Reduce
Renaissance Technologies history 10.54K $17.40K 0.00% Reduce
Morgan Stanley history 3.41K $5.63K 0.00% Reduce
Bank of America Corp history 1.47K $2.42K 0.00% Reduce
JPMorgan Chase & Co history 146 $241 0.00% Reduce
Wells Fargo & Co history 65 $107 0.00% Hold

Q1 2025 — 11 funds

FundSharesValuePortfolio WeightChange
Citadel Advisors history 1.10M $1.74M 0.00% Reduce
Vanguard Group history 475.65K $751.53K 0.00% Hold
Geode Capital Management history 133.49K $210.93K 0.00% Reduce
Renaissance Technologies history 115.14K $181.93K 0.00% Add
BlackRock Inc history 82.58K $130.47K 0.00% Reduce
Northern Trust Corp history 23.97K $37.87K 0.00% Hold
Bank of America Corp history 17.16K $27.12K 0.00% Add
Morgan Stanley history 12.81K $20.24K 0.00% Add
UBS Group AG history 7.58K $11.97K 0.00% Add
JPMorgan Chase & Co history 5.98K $9.45K 0.00% Add
Wells Fargo & Co history 65 $103 0.00% Hold

View all 23 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

No tracked fund fully exited this quarter.

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021
Citadel Advisors 468.46K 514.44K 30.53K — 1.04M 1.10M 1.23M 1.19M 1.21M 1.18M 1.18M — — — 54.35K 86.61K 46.30K 149.99K 141.86K 123.72K
Two Sigma Investments 438.82K 426.41K 220.00K 220.79K — — — — — — — — — — — — — — — 81.29K
Geode Capital Management 258.20K 322.71K 225.15K 137.12K 133.33K 133.49K 135.02K 134.59K 135.67K 106.78K 94.34K 27.53K 24.95K 24.95K 449.08K 450.20K 450.20K 470.44K 470.44K 470.44K
UBS Group AG 58.60K 179.78K 62.76K 5.57K — 7.58K 631 14 25.06K 16 846 184 1.09K 365 54.67K 10.46K 10.47K 255 243 4.04K
BlackRock Inc 44.41K 44.41K 44.41K 44.41K 44.41K 82.58K 83.31K 83.07K — — — — — — — — — — — —
Northern Trust Corp 43.68K 23.11K 23.11K 23.11K 23.11K 23.97K 23.97K 37.29K 37.66K 36.95K 36.95K — — — 89.47K 89.47K 89.47K 89.47K 89.48K 153.55K
Renaissance Technologies 23.30K 17.30K — — 10.54K 115.14K 24.94K 86.64K 63.11K 80.58K 46.38K 25.98K 36.08K 25.58K 866.83K 929.00K 939.53K 965.10K 904.53K 1.25M
Wells Fargo & Co 65 65 65 65 65 65 65 65 65 174 172 105 89 87 1.56K 2.56K 1.51K 1.46K 1.46K —
Morgan Stanley 43 43 43 911 3.41K 12.81K 4.30K 1.80K 1.80K 1.87K 1.87K 2.18K 2.21K 1.32K 23.35K 23.65K 42.11K 44.88K 127.66K 194.62K
JPMorgan Chase & Co 8 — 146 146 146 5.98K 314 177 176 169 146 146 8 8 171 181 171 5.26K 169 3.78K
Bank of America Corp — — 1.68K 1.53K 1.47K 17.16K 1.49K 2.28K 2.31K 2.19K 2.79K 3.42K 4.20K 4.75K 88.81K 88.68K 87.43K 89.53K 122.61K 110.27K
Vanguard Group — — 314.55K 190.38K 496.30K 475.65K 475.13K 443.52K 443.52K 69.63K 49.58K 44.90K 44.90K 37.86K 1.65M 1.65M 1.80M 1.48M 2.25M 2.44M
Fidelity Management & Research (FMR) — — — — — — 5 — — — — — — — — — — — 1.50K 1.50K
Goldman Sachs Group — — — — — — — — — — — — — — — — — — 115.70K 42.06K
Baillie Gifford & Co — — — — — — — — — — — — — — — — — 98.76K 98.76K 98.76K
BNY Mellon — — — — — — — — — — — — — — 26.63K 26.63K 26.63K 26.63K 26.63K 26.63K
Citigroup Inc — — — — — — — — — — — — — — — — 40.00K 1.20K — 2.89K
Franklin Resources — — — — — — — — — — — — — — 96.13K 96.13K 96.13K 142.60K 142.60K 1.92M
Marshall Wace — — — — — — — — — — — — — — — — — — 164.98K —
Millennium Management — — — — — — — — — 10.99K 17.27K — — 27.31K 488.01K 198.71K 164.41K 354.00K 431.49K 432.42K

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