VYNE — VYNE THERAPEUTICS INC
As of Q2 2026, 10 SEC-registered investment managers reported holding VYNE (VYNE THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $869.08K across 1.34M shares. That is -12.6% by share count (-192.70K shares) versus the previous quarter, while reported value moved -4.8%. Ownership is concentrated: the five largest holders account for 95.0% of reported value and the top ten for 100.0%.
Compared with the prior quarter, 1 opened new positions, 3 added to existing stakes, 3 trimmed. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 10 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Citadel Advisors history | 468.46K | $304.82K | 0.00% | Reduce |
| Two Sigma Investments history | 438.82K | $285.54K | 0.00% | Add |
| Geode Capital Management history | 258.20K | $168.02K | 0.00% | Reduce |
| UBS Group AG history | 58.60K | $38.15K | 0.00% | Reduce |
| BlackRock Inc history | 44.41K | $28.89K | 0.00% | Hold |
| Northern Trust Corp history | 43.68K | $28.42K | 0.00% | Add |
| Renaissance Technologies history | 23.30K | $15.16K | 0.00% | Add |
| Wells Fargo & Co history | 65 | $42 | 0.00% | Hold |
| Morgan Stanley history | 43 | $28 | 0.00% | Hold |
| JPMorgan Chase & Co history | 8 | $5 | 0.00% | New |
Q1 2026 — 9 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Citadel Advisors history | 514.44K | $307.38K | 0.00% | Add |
| Two Sigma Investments history | 426.41K | $254.78K | 0.00% | Add |
| Geode Capital Management history | 322.71K | $192.82K | 0.00% | Add |
| UBS Group AG history | 179.78K | $107.51K | 0.00% | Add |
| BlackRock Inc history | 44.41K | $26.53K | 0.00% | Hold |
| Northern Trust Corp history | 23.11K | $13.81K | 0.00% | Hold |
| Renaissance Technologies history | 17.30K | $10.34K | 0.00% | New |
| Wells Fargo & Co history | 65 | $39 | 0.00% | Hold |
| Morgan Stanley history | 43 | $26 | 0.00% | Hold |
Q4 2025 — 11 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 314.55K | $182.44K | 0.00% | Add |
| Geode Capital Management history | 225.15K | $130.61K | 0.00% | Add |
| Two Sigma Investments history | 220.00K | $127.62K | 0.00% | Hold |
| UBS Group AG history | 62.76K | $36.40K | 0.00% | Add |
| BlackRock Inc history | 44.41K | $25.76K | 0.00% | Hold |
| Citadel Advisors history | 30.53K | $17.71K | 0.00% | New |
| Northern Trust Corp history | 23.11K | $13.41K | 0.00% | Hold |
| Bank of America Corp history | 1.68K | $973 | 0.00% | Add |
| JPMorgan Chase & Co history | 146 | $85 | 0.00% | Hold |
| Wells Fargo & Co history | 65 | $38 | 0.00% | Hold |
| Morgan Stanley history | 43 | $25 | 0.00% | Reduce |
Q3 2025 — 10 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Two Sigma Investments history | 220.79K | $73.96K | 0.00% | New |
| Vanguard Group history | 190.38K | $63.78K | 0.00% | Reduce |
| Geode Capital Management history | 137.12K | $45.94K | 0.00% | Add |
| BlackRock Inc history | 44.41K | $14.88K | 0.00% | Hold |
| Northern Trust Corp history | 23.11K | $7.74K | 0.00% | Hold |
| UBS Group AG history | 5.57K | $1.87K | 0.00% | New |
| Bank of America Corp history | 1.53K | $513 | 0.00% | Add |
| Morgan Stanley history | 911 | $305 | 0.00% | Reduce |
| JPMorgan Chase & Co history | 146 | $49 | 0.00% | Hold |
| Wells Fargo & Co history | 65 | $22 | 0.00% | Hold |
Q2 2025 — 10 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Citadel Advisors history | 1.04M | $1.72M | 0.00% | Reduce |
| Vanguard Group history | 496.30K | $818.89K | 0.00% | Add |
| Geode Capital Management history | 133.33K | $220.00K | 0.00% | Hold |
| BlackRock Inc history | 44.41K | $73.27K | 0.00% | Reduce |
| Northern Trust Corp history | 23.11K | $38.13K | 0.00% | Reduce |
| Renaissance Technologies history | 10.54K | $17.40K | 0.00% | Reduce |
| Morgan Stanley history | 3.41K | $5.63K | 0.00% | Reduce |
| Bank of America Corp history | 1.47K | $2.42K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 146 | $241 | 0.00% | Reduce |
| Wells Fargo & Co history | 65 | $107 | 0.00% | Hold |
Q1 2025 — 11 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Citadel Advisors history | 1.10M | $1.74M | 0.00% | Reduce |
| Vanguard Group history | 475.65K | $751.53K | 0.00% | Hold |
| Geode Capital Management history | 133.49K | $210.93K | 0.00% | Reduce |
| Renaissance Technologies history | 115.14K | $181.93K | 0.00% | Add |
| BlackRock Inc history | 82.58K | $130.47K | 0.00% | Reduce |
| Northern Trust Corp history | 23.97K | $37.87K | 0.00% | Hold |
| Bank of America Corp history | 17.16K | $27.12K | 0.00% | Add |
| Morgan Stanley history | 12.81K | $20.24K | 0.00% | Add |
| UBS Group AG history | 7.58K | $11.97K | 0.00% | Add |
| JPMorgan Chase & Co history | 5.98K | $9.45K | 0.00% | Add |
| Wells Fargo & Co history | 65 | $103 | 0.00% | Hold |
New Positions (Q2 2026)
- JPMorgan Chase & Co 8 sh · $5
Fully Exited (vs previous quarter)
No tracked fund fully exited this quarter.
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Citadel Advisors | 468.46K | 514.44K | 30.53K | — | 1.04M | 1.10M | 1.23M | 1.19M | 1.21M | 1.18M | 1.18M | — | — | — | 54.35K | 86.61K | 46.30K | 149.99K | 141.86K | 123.72K |
| Two Sigma Investments | 438.82K | 426.41K | 220.00K | 220.79K | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 81.29K |
| Geode Capital Management | 258.20K | 322.71K | 225.15K | 137.12K | 133.33K | 133.49K | 135.02K | 134.59K | 135.67K | 106.78K | 94.34K | 27.53K | 24.95K | 24.95K | 449.08K | 450.20K | 450.20K | 470.44K | 470.44K | 470.44K |
| UBS Group AG | 58.60K | 179.78K | 62.76K | 5.57K | — | 7.58K | 631 | 14 | 25.06K | 16 | 846 | 184 | 1.09K | 365 | 54.67K | 10.46K | 10.47K | 255 | 243 | 4.04K |
| BlackRock Inc | 44.41K | 44.41K | 44.41K | 44.41K | 44.41K | 82.58K | 83.31K | 83.07K | — | — | — | — | — | — | — | — | — | — | — | — |
| Northern Trust Corp | 43.68K | 23.11K | 23.11K | 23.11K | 23.11K | 23.97K | 23.97K | 37.29K | 37.66K | 36.95K | 36.95K | — | — | — | 89.47K | 89.47K | 89.47K | 89.47K | 89.48K | 153.55K |
| Renaissance Technologies | 23.30K | 17.30K | — | — | 10.54K | 115.14K | 24.94K | 86.64K | 63.11K | 80.58K | 46.38K | 25.98K | 36.08K | 25.58K | 866.83K | 929.00K | 939.53K | 965.10K | 904.53K | 1.25M |
| Wells Fargo & Co | 65 | 65 | 65 | 65 | 65 | 65 | 65 | 65 | 65 | 174 | 172 | 105 | 89 | 87 | 1.56K | 2.56K | 1.51K | 1.46K | 1.46K | — |
| Morgan Stanley | 43 | 43 | 43 | 911 | 3.41K | 12.81K | 4.30K | 1.80K | 1.80K | 1.87K | 1.87K | 2.18K | 2.21K | 1.32K | 23.35K | 23.65K | 42.11K | 44.88K | 127.66K | 194.62K |
| JPMorgan Chase & Co | 8 | — | 146 | 146 | 146 | 5.98K | 314 | 177 | 176 | 169 | 146 | 146 | 8 | 8 | 171 | 181 | 171 | 5.26K | 169 | 3.78K |
| Bank of America Corp | — | — | 1.68K | 1.53K | 1.47K | 17.16K | 1.49K | 2.28K | 2.31K | 2.19K | 2.79K | 3.42K | 4.20K | 4.75K | 88.81K | 88.68K | 87.43K | 89.53K | 122.61K | 110.27K |
| Vanguard Group | — | — | 314.55K | 190.38K | 496.30K | 475.65K | 475.13K | 443.52K | 443.52K | 69.63K | 49.58K | 44.90K | 44.90K | 37.86K | 1.65M | 1.65M | 1.80M | 1.48M | 2.25M | 2.44M |
| Fidelity Management & Research (FMR) | — | — | — | — | — | — | 5 | — | — | — | — | — | — | — | — | — | — | — | 1.50K | 1.50K |
| Goldman Sachs Group | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 115.70K | 42.06K |
| Baillie Gifford & Co | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 98.76K | 98.76K | 98.76K |
| BNY Mellon | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 26.63K | 26.63K | 26.63K | 26.63K | 26.63K | 26.63K |
| Citigroup Inc | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 40.00K | 1.20K | — | 2.89K |
| Franklin Resources | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 96.13K | 96.13K | 96.13K | 142.60K | 142.60K | 1.92M |
| Marshall Wace | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 164.98K | — |
| Millennium Management | — | — | — | — | — | — | — | — | — | 10.99K | 17.27K | — | — | 27.31K | 488.01K | 198.71K | 164.41K | 354.00K | 431.49K | 432.42K |