TYRA — TYRA BIOSCIENCES INC
As of Q2 2026, 28 SEC-registered investment managers reported holding TYRA (TYRA BIOSCIENCES INC) in their latest 13F filings, with a combined reported value of $545.35M across 19.85M shares. That is -9.9% by share count (-2.17M shares) versus the previous quarter, while reported value moved -32.3%. Ownership is concentrated: the five largest holders account for 81.8% of reported value and the top ten for 91.7%.
Compared with the prior quarter, 2 opened new positions, 20 added to existing stakes, 6 trimmed, 4 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
TYRA is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
| Fund | Quarter | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | Q2 2026 | 8.92M | $284.92M | 0.01% | Add |
| Janus Henderson Group history | Q1 2026 | 3.89M | $148.87M | 0.07% | Add |
| Farallon Capital Management history | Q1 2026 | 3.58M | $137.15M | 0.90% | Add |
| BlackRock Inc history | Q2 2026 | 3.03M | $96.84M | 0.00% | Add |
| Vanguard Group history | Q4 2025 | 1.57M | $41.35M | 0.00% | Add |
| Geode Capital Management history | Q2 2026 | 970.73K | $31.01M | 0.00% | Add |
| Marshall Wace history | Q2 2026 | 583.13K | $18.63M | 0.01% | Add |
| Goldman Sachs Group history | Q2 2026 | 463.48K | $14.80M | 0.00% | Reduce |
| Two Sigma Investments history | Q2 2026 | 449.81K | $14.37M | 0.01% | Add |
| Balyasny Asset Management history | Q1 2026 | 351.48K | $13.46M | 0.02% | Reduce |
| Bank of America Corp history | Q2 2026 | 349.73K | $11.17M | 0.00% | Add |
| Northern Trust Corp history | Q2 2026 | 310.08K | $9.90M | 0.00% | Add |
| Morgan Stanley history | Q2 2026 | 300.32K | $9.59M | 0.00% | Add |
| Citadel Advisors history | Q2 2026 | 278.31K | $8.89M | 0.00% | Add |
| Charles Schwab Investment Management history | Q2 2026 | 267.70K | $8.55M | 0.00% | Add |
| Point72 Asset Management history | Q1 2026 | 218.95K | $8.39M | 0.01% | Reduce |
| Millennium Management history | Q2 2026 | 202.67K | $6.47M | 0.00% | Reduce |
| Franklin Resources history | Q2 2026 | 192.34K | $6.14M | 0.00% | Add |
| JPMorgan Chase & Co history | Q2 2026 | 178.26K | $5.74M | 0.00% | New |
| UBS Group AG history | Q2 2026 | 129.94K | $4.15M | 0.00% | Add |
New Positions (Q2 2026)
- JPMorgan Chase & Co 178.26K sh · $5.74M
- D. E. Shaw & Co 20.19K sh · $644.84K
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 3.89M sh · $148.87M
- Farallon Capital Management sold 3.58M sh · $137.15M
- Balyasny Asset Management sold 351.48K sh · $13.46M
- Point72 Asset Management sold 218.95K sh · $8.39M
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q3 2021 | Q4 2021 | Q1 2022 | Q2 2022 | Q3 2022 | Q4 2022 | Q1 2023 | Q2 2023 | Q3 2023 | Q4 2023 | Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fidelity Management & Research (FMR) | 1.91M | 3.47M | 4.09M | 3.97M | 4.03M | 3.88M | 3.15M | 4.12M | 3.90M | 2.77M | 3.98M | 3.35M | 3.37M | 3.11M | 1.71M | 12.20K | 12.53K | 12.56K | 7.75M | 8.92M |
| BlackRock Inc | — | — | — | — | — | — | — | — | — | — | — | — | 1.52M | 1.72M | 1.70M | 1.89M | 1.87M | 2.09M | 2.22M | 3.03M |
| Geode Capital Management | — | 206.38K | 210.55K | 225.41K | 247.45K | 253.69K | 286.10K | 290.00K | 314.48K | 333.47K | 416.81K | 522.67K | 523.19K | 517.58K | 516.29K | 567.13K | 597.45K | 657.76K | 658.48K | 970.73K |
| Marshall Wace | — | — | — | — | — | — | — | — | — | 30.00K | 19.64K | — | 19.61K | 54.08K | 380.70K | 428.11K | 602.01K | 711.89K | 197.75K | 583.13K |
| Goldman Sachs Group | 207.28K | — | — | — | — | — | — | — | — | — | 14.08K | 114.87K | 89.08K | 64.11K | 78.01K | 105.59K | 100.15K | 182.39K | 550.33K | 463.48K |
| Two Sigma Investments | — | — | — | — | — | — | — | — | — | — | 41.74K | 35.27K | 39.18K | 46.27K | 64.82K | 105.83K | 199.44K | 107.02K | 101.62K | 449.81K |
| Bank of America Corp | 885 | 5.72K | 64.13K | 19.72K | 13.79K | 20.96K | 58.01K | 20.41K | 22.16K | 22.12K | 33.03K | 49.52K | 54.35K | 66.16K | 83.52K | 372.97K | 134.32K | 38.31K | 209.92K | 349.73K |
| Northern Trust Corp | — | 103.49K | 100.10K | 103.13K | 103.81K | 105.77K | 107.54K | 140.17K | 141.60K | 152.25K | 156.47K | 155.45K | 214.35K | 222.76K | 216.45K | 205.31K | 208.49K | 200.96K | 218.51K | 310.08K |
| Morgan Stanley | — | 35.75K | 1.57K | 13.44K | 12.52K | 10.40K | 15.31K | 18.77K | 18.28K | 35.67K | 35.24K | 64.53K | 68.92K | 74.15K | 180.59K | 378.40K | 322.14K | 118.90K | 120.48K | 300.32K |
| Citadel Advisors | — | 78.31K | 78.31K | 74.84K | 40.62K | 31.82K | — | — | — | — | 21.09K | — | 46.65K | 65.39K | 115.88K | 216.14K | 134.79K | 12.50K | 47.80K | 278.31K |
| Charles Schwab Investment Management | — | 79.35K | 80.46K | 81.30K | 96.17K | 98.50K | 102.37K | 104.66K | 110.21K | 110.54K | 152.21K | 169.94K | 173.74K | 170.60K | 164.11K | 178.10K | 201.59K | 199.43K | 199.11K | 267.70K |
| Millennium Management | 93.50K | 109.52K | — | — | — | — | 13.47K | 21.59K | — | — | — | — | 10.50K | 315.14K | 404.17K | 407.46K | 144.02K | 114.39K | 261.58K | 202.67K |
| Franklin Resources | — | — | — | — | — | — | — | — | — | — | — | — | 12.65K | 12.75K | — | — | — | 12.97K | 12.97K | 192.34K |
| JPMorgan Chase & Co | — | 154.58K | 228.48K | 224.49K | 219.55K | 199.21K | 182.35K | 423.42K | 397.62K | 401.71K | 380.60K | 364.75K | 368.65K | 91.11K | 85.49K | 102.92K | 74.23K | 71.17K | — | 178.26K |
| UBS Group AG | — | 5.47K | 1.74K | — | 91 | 3.59K | 4.62K | 8.00K | 5.31K | 4.98K | 14.17K | 7.58K | 10.96K | 47.85K | 46.29K | 46.27K | 59.14K | 58.86K | 61.56K | 129.94K |
| BNY Mellon | — | 20.57K | 30.62K | 31.91K | 39.25K | 46.37K | 41.53K | 40.80K | 41.87K | 41.95K | 43.73K | 58.09K | 42.79K | 45.01K | 41.08K | 54.04K | 57.16K | 60.90K | 72.21K | 103.72K |
| Citigroup Inc | 440 | 3.17K | 459 | 934 | 200 | 89 | — | 4.17K | 19 | 2.03K | 7.11K | 4.43K | 14.67K | 16.80K | 15.51K | 9.50K | 1.71K | 3.82K | 5.99K | 62.28K |
| Wellington Management Group | 695.37K | 589.78K | 251.22K | 54.86K | 85.18K | 78.16K | 84.26K | 79.44K | 94.11K | 102.44K | 101.79K | 117.03K | 90.83K | 94.86K | 104.09K | 103.08K | 82.87K | 104.31K | 77.17K | 59.60K |
| Manulife Financial | — | — | — | — | — | — | — | — | — | — | — | — | 14.18K | 13.37K | — | — | — | 8.36K | 40.22K | 44.33K |
| Deutsche Bank AG | — | 7.39K | 6.61K | 5.80K | 4.92K | 5.01K | 8.14K | 6.22K | 6.22K | 6.22K | 6.01K | 9.33K | 12.44K | 18.91K | 16.98K | 13.30K | 15.48K | 16.38K | 20.50K | 36.94K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
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