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SYBX — SYNLOGIC INC

Reported value held$1.30M
Funds holding (latest)22
Sector—

SYBX (SYNLOGIC INC) is tracked on HoldingsHub across five years of quarterly 13F filings. 22 funds have reported positions historically, with the sum of their latest reported stakes valued at $1.30M. No fund in our coverage reported a position in the latest filing period, which typically means the stock has fallen out of the tracked funds' portfolios rather than that it cannot be bought.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q4 2025 — 12 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 201.06K $225.19K 0.00% Add
Citadel Advisors history 141.61K $158.60K 0.00% Add
Renaissance Technologies history 85.63K $95.90K 0.00% Add
Geode Capital Management history 71.64K $80.25K 0.00% Add
BlackRock Inc history 19.76K $22.13K 0.00% Hold
Northern Trust Corp history 19.47K $21.80K 0.00% Hold
Fidelity Management & Research (FMR) history 5.32K $5.96K 0.00% Hold
UBS Group AG history 2.53K $2.83K 0.00% New
Morgan Stanley history 1.09K $1.23K 0.00% Hold
Bank of America Corp history 66 $73 0.00% Add
JPMorgan Chase & Co history 1 $1 0.00% Hold
Citigroup Inc history 1 $1 0.00% Hold

Q3 2025 — 12 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 196.46K $332.02K 0.00% Add
Geode Capital Management history 67.67K $114.36K 0.00% Add
Renaissance Technologies history 39.51K $65.90K 0.00% Add
Citadel Advisors history 29.01K $49.03K 0.00% New
BlackRock Inc history 19.76K $32.95K 0.00% Hold
Northern Trust Corp history 19.47K $32.47K 0.00% New
Fidelity Management & Research (FMR) history 5.32K $9.00K 0.00% Reduce
Morgan Stanley history 1.09K $1.83K 0.00% Reduce
Bank of America Corp history 64 $107 0.00% Reduce
Wells Fargo & Co history 5 $8 0.00% New
JPMorgan Chase & Co history 1 $2 0.00% Hold
Citigroup Inc history 1 $2 0.00% New

Q2 2025 — 8 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 183.00K $232.41K 0.00% Hold
Fidelity Management & Research (FMR) history 166.00K $210.82K 0.00% Hold
Geode Capital Management history 66.24K $84.13K 0.00% Hold
Renaissance Technologies history 23.81K $30.24K 0.00% Add
BlackRock Inc history 19.76K $25.09K 0.00% Hold
Morgan Stanley history 1.12K $1.43K 0.00% Reduce
Bank of America Corp history 69 $87 0.00% Add
JPMorgan Chase & Co history 1 $1 0.00% Reduce

Q1 2025 — 9 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 183.00K $226.92K 0.00% Hold
Fidelity Management & Research (FMR) history 166.50K $206.46K 0.00% Hold
Geode Capital Management history 66.24K $82.14K 0.00% Reduce
Renaissance Technologies history 23.51K $29.15K 0.00% Add
BlackRock Inc history 19.76K $24.50K 0.00% Hold
Citadel Advisors history 17.52K $21.73K 0.00% New
Morgan Stanley history 2.12K $2.63K 0.00% Hold
Bank of America Corp history 63 $78 0.00% Add
JPMorgan Chase & Co history 7 $8 0.00% Reduce

Q4 2024 — 8 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 183.00K $250.71K 0.00% Hold
Fidelity Management & Research (FMR) history 166.72K $228.41K 0.00% Hold
Geode Capital Management history 68.44K $93.78K 0.00% Add
Renaissance Technologies history 22.31K $31.23K 0.00% Reduce
BlackRock Inc history 19.76K $27.66K 0.00% Hold
Morgan Stanley history 2.12K $2.98K 0.00% Hold
Bank of America Corp history 61 $85 0.00% Hold
JPMorgan Chase & Co history 8 $11 0.00% Hold

Q3 2024 — 9 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 183.00K $272.67K 0.00% Hold
Fidelity Management & Research (FMR) history 166.72K $248.42K 0.00% Reduce
Renaissance Technologies history 71.93K $107.17K 0.00% Reduce
Geode Capital Management history 64.23K $95.72K 0.00% Add
BlackRock Inc history 19.76K $29.44K 0.00% New
Citadel Advisors history 16.45K $24.51K 0.00% Reduce
Morgan Stanley history 2.12K $3.17K 0.00% Hold
Bank of America Corp history 61 $91 0.00% Reduce
JPMorgan Chase & Co history 8 $11 0.00% Hold

View all 22 fund holders →

New Positions (latest)

No fund opened a new position this quarter.

Fully Exited (vs previous quarter)

No tracked fund fully exited this quarter.

Fund Position History — shares by quarter (top 20 funds)

FundQ4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021Q2 2021Q1 2021
Vanguard Group 201.06K 196.46K 183.00K 183.00K 183.00K 183.00K 183.00K 183.00K 188.43K 149.57K 2.24M 2.24M 2.24M 2.24M 2.24M 2.24M 2.25M 2.22M 1.73M 839.36K
Citadel Advisors 141.61K 29.01K — 17.52K — 16.45K 28.85K 21.17K 10.86K — — — — 15.00K — — 11.29K 12.03K — —
Renaissance Technologies 85.63K 39.51K 23.81K 23.51K 22.31K 71.93K 100.53K 118.44K 54.63K — 214.30K 91.90K 96.40K 115.60K 55.00K 51.30K 54.70K 188.67K — —
Geode Capital Management 71.64K 67.67K 66.24K 66.24K 68.44K 64.23K 59.59K 47.60K 44.42K 30.33K 400.01K 400.01K 400.01K 393.99K 393.99K 379.57K 328.99K 308.51K — —
BlackRock Inc 19.76K 19.76K 19.76K 19.76K 19.76K 19.76K — — — — — — — — — — — — — —
Northern Trust Corp 19.47K 19.47K — — — — — — — — 93.86K 93.86K 93.86K 93.86K 93.86K 93.86K 77.16K 66.94K — —
Fidelity Management & Research (FMR) 5.32K 5.32K 166.00K 166.50K 166.72K 166.72K 230.21K 230.21K 258.64K 646.85K 10.14M 10.58M 10.58M 10.53M 10.54M 10.53M 10.46M 10.11M — —
UBS Group AG 2.53K — — — — — 13.23K — — — — 8.80K — — — 35.14K — 3.91K — —
Morgan Stanley 1.09K 1.09K 1.12K 2.12K 2.12K 2.12K 2.12K 2.12K 2.12K 1.63K 18.90K 679.50K 680.27K 679.65K 30.89K 36.53K 49.90K 76.16K — —
Bank of America Corp 66 64 69 63 61 61 63 — 4 — — — 116 — — — 10.87K 1.42K — —
JPMorgan Chase & Co 1 1 1 7 8 8 8 12 8 6 19 439 468 19 19 19 19 19 — —
Citigroup Inc 1 1 — — — — — — — — — — — — — — — — — —
Wells Fargo & Co — 5 — — — — — 40 53 36 524 522 317 308 348 318 316 215 — —
Goldman Sachs Group — — — — — — — — — 11.01K — — — — 20.00K — — — — —
Two Sigma Investments — — — — — — — — — — 74.35K 74.35K 81.95K 94.00K 97.31K 130.06K 346.11K 447.65K — —
BNY Mellon — — — — — — — — — — — 67.72K 67.72K 68.18K 68.18K 68.58K 68.58K 68.58K — —
Franklin Resources — — — — — — — — — — 78.00K 78.00K 78.00K 78.00K 77.12K 102.10K 101.44K 101.70K — —
Millennium Management — — — — — — — — — — 19.02K 58.75K 95.43K 22.01K 125.13K 77.97K 293.86K 101.83K — —
PNC Financial Services — — — — — — — — — 466 — — — — — — — — — —
Prudential Financial — — — — — — — — — — — — 30.20K — — — — — — —

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