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SPRB — SPRUCE BIOSCIENCES INC

Reported value held$38.21M
Funds holding (latest)24
SectorHealth Care
Funds holding (Q2 2026)19
Institutional value$33.39M · 618.26K sh
New / Add / Cut / Exit10 / 7 / 2 / 1
Top-5 / Top-10 concentration81.5% / 96.3%
Institutional holdings change Accumulating +98.0% (+305.98K sh)
Institutional value change Up +63.6%

As of Q2 2026, 19 SEC-registered investment managers reported holding SPRB (SPRUCE BIOSCIENCES INC) in their latest 13F filings, with a combined reported value of $33.39M across 618.26K shares. That is +98.0% by share count (+305.98K shares) versus the previous quarter, while reported value moved +63.6%. Ownership is concentrated: the five largest holders account for 81.5% of reported value and the top ten for 96.3%.

Compared with the prior quarter, 10 opened new positions, 7 added to existing stakes, 2 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

SPRB is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 19 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 187.84K $10.14M 0.00% Add
Millennium Management history 160.98K $8.69M 0.00% Add
Geode Capital Management history 70.55K $3.81M 0.00% Add
Citadel Advisors history 51.91K $2.80M 0.00% Reduce
Goldman Sachs Group history 32.35K $1.75M 0.00% Add
Point72 Asset Management history 28.28K $1.53M 0.00% New
UBS Group AG history 23.38K $1.26M 0.00% Add
Northern Trust Corp history 21.08K $1.14M 0.00% New
Balyasny Asset Management history 12.14K $655.45K 0.00% Reduce
BNY Mellon history 6.78K $366.06K 0.00% New
Charles Schwab Investment Management history 5.90K $318.38K 0.00% New
Renaissance Technologies history 4.70K $253.80K 0.00% New
Morgan Stanley history 4.41K $238.19K 0.00% Add
Deutsche Bank AG history 2.65K $143.21K 0.00% New
Wells Fargo & Co history 2.33K $125.77K 0.00% New
Citigroup Inc history 1.26K $68.31K 0.00% Add
JPMorgan Chase & Co history 1.13K $62.98K 0.00% New
Fidelity Management & Research (FMR) history 343 $18.52K 0.00% New
Legal & General Investment Management America history 264 $14.22K 0.00% New

Q1 2026 — 10 funds

FundSharesValuePortfolio WeightChange
Millennium Management history 111.89K $7.31M 0.00% New
Citadel Advisors history 70.00K $4.57M 0.00% Hold
Wellington Management Group history 48.80K $3.19M 0.00% Reduce
Balyasny Asset Management history 40.00K $2.61M 0.00% Hold
BlackRock Inc history 16.94K $1.11M 0.00% Hold
Geode Capital Management history 12.89K $842.73K 0.00% Add
Goldman Sachs Group history 5.51K $359.82K 0.00% New
UBS Group AG history 3.92K $256.11K 0.00% Reduce
Morgan Stanley history 1.42K $92.47K 0.00% Add
Citigroup Inc history 939 $61.36K 0.00% New

Q4 2025 — 10 funds

FundSharesValuePortfolio WeightChange
Citadel Advisors history 70.00K $6.10M 0.00% New
Wellington Management Group history 58.95K $5.14M 0.00% New
Balyasny Asset Management history 40.00K $3.48M 0.01% New
Vanguard Group history 17.87K $1.56M 0.00% New
BlackRock Inc history 16.94K $1.48M 0.00% New
Geode Capital Management history 12.73K $1.11M 0.00% New
UBS Group AG history 4.90K $427.01K 0.00% Add
Northern Trust Corp history 2.42K $210.98K 0.00% New
Morgan Stanley history 388 $33.80K 0.00% Add
Bank of America Corp history 93 $8.10K 0.00% Add

Q3 2025 — 3 funds

FundSharesValuePortfolio WeightChange
UBS Group AG history 132 $1.18K 0.00% New
Morgan Stanley history 98 $878 0.00% New
Bank of America Corp history 3 $27 0.00% New

Q1 2025 — 11 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 843.84K $244.72K 0.00% Hold
Renaissance Technologies history 382.90K $111.08K 0.00% Reduce
Geode Capital Management history 276.71K $80.29K 0.00% Add
BlackRock Inc history 124.73K $36.19K 0.00% Hold
UBS Group AG history 116.46K $33.77K 0.00% Add
Northern Trust Corp history 32.72K $9.49K 0.00% Reduce
Two Sigma Investments history 20.55K $5.96K 0.00% Hold
Citigroup Inc history 11.08K $3.21K 0.00% New
Morgan Stanley history 7.40K $2.15K 0.00% Add
Bank of America Corp history 233 $68 0.00% Add
JPMorgan Chase & Co history 65 $19 0.00% Reduce

Q4 2024 — 10 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 843.84K $354.42K 0.00% Hold
Renaissance Technologies history 405.90K $170.48K 0.00% Reduce
Geode Capital Management history 273.79K $115.01K 0.00% Add
BlackRock Inc history 124.73K $52.39K 0.00% Hold
UBS Group AG history 86.05K $36.14K 0.00% Add
Northern Trust Corp history 80.31K $33.73K 0.00% Add
Two Sigma Investments history 20.62K $8.66K 0.00% Reduce
Morgan Stanley history 2.13K $896 0.00% Hold
Bank of America Corp history 222 $93 0.00% Hold
JPMorgan Chase & Co history 69 $29 0.00% Reduce

View all 24 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021
BlackRock Inc 187.84K 16.94K 16.94K — 124.73K 124.73K 124.73K — — — — — — — — — — — —
Millennium Management 160.98K 111.89K — — — — — — 102.22K 510.44K 583.47K 577.66K 608.85K 147.50K 145.01K 190.15K — — 38.62K
Geode Capital Management 70.55K 12.89K 12.73K — 276.71K 273.79K 261.95K 204.00K 200.16K 167.40K 167.40K 217.91K 60.62K 60.62K 60.76K 60.76K 127.03K 142.47K 111.42K
Citadel Advisors 51.91K 70.00K 70.00K — — — 80.35K 146.81K 120.98K 108.24K 75.03K 71.28K 1.70M 1.75M 1.73M 1.72M 1.72M 1.73M 1.70M
Goldman Sachs Group 32.35K 5.51K — — — — — — — — — — 182.66K — 19.55K 59.61K 42.67K 230.80K 12.96K
Point72 Asset Management 28.28K — — — — — — — — — — — — — — — — — —
UBS Group AG 23.38K 3.92K 4.90K 132 116.46K 86.05K 13 131.92K 15.81K 485 13 13 960 5.64K 7.51K 5.85K 3.91K 5.35K —
Northern Trust Corp 21.08K — 2.42K — 32.72K 80.31K 74.93K 74.93K 74.95K 96.69K 48.66K 57.10K 13.74K 14.07K 14.07K 14.07K 70.69K 75.01K 74.67K
Balyasny Asset Management 12.14K 40.00K 40.00K — — — — — 22.51K — — — — — — — — — —
BNY Mellon 6.78K — — — — — — — — — 89.12K 91.45K 92.08K 92.08K 92.76K 92.76K 116.50K 27.89K 27.45K
Charles Schwab Investment Management 5.90K — — — — — — 15.29K 15.29K 15.29K 15.29K 15.29K — — — — 18.42K 18.42K 18.42K
Renaissance Technologies 4.70K — — — 382.90K 405.90K 609.70K 366.10K 271.00K 185.10K 207.78K 239.10K 160.10K 138.42K 143.10K 151.40K 111.70K 39.80K 34.00K
Morgan Stanley 4.41K 1.42K 388 98 7.40K 2.13K 2.13K 2.13K 21.52K 2.13K 2.13K 2.13K 3.15K 3.34K 23.17K 60.66K 11.42K 12.39K 75.91K
Deutsche Bank AG 2.65K — — — — — — — — — — — — — — — 12.30K 5.28K 5.00K
Wells Fargo & Co 2.33K — — — — — — — 143 141 130 186 67 466 664 1.06K 4.85K 9.47K 10.92K
Citigroup Inc 1.26K 939 — — 11.08K — — — — — — — — — — 393 1.19K 2.21K 1.38K
JPMorgan Chase & Co 1.13K — — — 65 69 71 72 11 11 11 23.56K 58.18K 11 11 11 113.38K 118.37K 125.46K
Fidelity Management & Research (FMR) 343 — — — — — — — 103 — 36 — 50 — 416 415 6.98K 114.50K 951.53K
Legal & General Investment Management America 264 — — — — — — — — — — — — — — 782 782 782 782
Bank of America Corp — — 93 3 233 222 223 150 26.13K 13 310 — 249 11 1.32K 2.85K 4.91K 83.10K 16.82K

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