SPRB — SPRUCE BIOSCIENCES INC
As of Q2 2026, 19 SEC-registered investment managers reported holding SPRB (SPRUCE BIOSCIENCES INC) in their latest 13F filings, with a combined reported value of $33.39M across 618.26K shares. That is +98.0% by share count (+305.98K shares) versus the previous quarter, while reported value moved +63.6%. Ownership is concentrated: the five largest holders account for 81.5% of reported value and the top ten for 96.3%.
Compared with the prior quarter, 10 opened new positions, 7 added to existing stakes, 2 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
SPRB is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 19 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 187.84K | $10.14M | 0.00% | Add |
| Millennium Management history | 160.98K | $8.69M | 0.00% | Add |
| Geode Capital Management history | 70.55K | $3.81M | 0.00% | Add |
| Citadel Advisors history | 51.91K | $2.80M | 0.00% | Reduce |
| Goldman Sachs Group history | 32.35K | $1.75M | 0.00% | Add |
| Point72 Asset Management history | 28.28K | $1.53M | 0.00% | New |
| UBS Group AG history | 23.38K | $1.26M | 0.00% | Add |
| Northern Trust Corp history | 21.08K | $1.14M | 0.00% | New |
| Balyasny Asset Management history | 12.14K | $655.45K | 0.00% | Reduce |
| BNY Mellon history | 6.78K | $366.06K | 0.00% | New |
| Charles Schwab Investment Management history | 5.90K | $318.38K | 0.00% | New |
| Renaissance Technologies history | 4.70K | $253.80K | 0.00% | New |
| Morgan Stanley history | 4.41K | $238.19K | 0.00% | Add |
| Deutsche Bank AG history | 2.65K | $143.21K | 0.00% | New |
| Wells Fargo & Co history | 2.33K | $125.77K | 0.00% | New |
| Citigroup Inc history | 1.26K | $68.31K | 0.00% | Add |
| JPMorgan Chase & Co history | 1.13K | $62.98K | 0.00% | New |
| Fidelity Management & Research (FMR) history | 343 | $18.52K | 0.00% | New |
| Legal & General Investment Management America history | 264 | $14.22K | 0.00% | New |
Q1 2026 — 10 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Millennium Management history | 111.89K | $7.31M | 0.00% | New |
| Citadel Advisors history | 70.00K | $4.57M | 0.00% | Hold |
| Wellington Management Group history | 48.80K | $3.19M | 0.00% | Reduce |
| Balyasny Asset Management history | 40.00K | $2.61M | 0.00% | Hold |
| BlackRock Inc history | 16.94K | $1.11M | 0.00% | Hold |
| Geode Capital Management history | 12.89K | $842.73K | 0.00% | Add |
| Goldman Sachs Group history | 5.51K | $359.82K | 0.00% | New |
| UBS Group AG history | 3.92K | $256.11K | 0.00% | Reduce |
| Morgan Stanley history | 1.42K | $92.47K | 0.00% | Add |
| Citigroup Inc history | 939 | $61.36K | 0.00% | New |
Q4 2025 — 10 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Citadel Advisors history | 70.00K | $6.10M | 0.00% | New |
| Wellington Management Group history | 58.95K | $5.14M | 0.00% | New |
| Balyasny Asset Management history | 40.00K | $3.48M | 0.01% | New |
| Vanguard Group history | 17.87K | $1.56M | 0.00% | New |
| BlackRock Inc history | 16.94K | $1.48M | 0.00% | New |
| Geode Capital Management history | 12.73K | $1.11M | 0.00% | New |
| UBS Group AG history | 4.90K | $427.01K | 0.00% | Add |
| Northern Trust Corp history | 2.42K | $210.98K | 0.00% | New |
| Morgan Stanley history | 388 | $33.80K | 0.00% | Add |
| Bank of America Corp history | 93 | $8.10K | 0.00% | Add |
Q3 2025 — 3 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| UBS Group AG history | 132 | $1.18K | 0.00% | New |
| Morgan Stanley history | 98 | $878 | 0.00% | New |
| Bank of America Corp history | 3 | $27 | 0.00% | New |
Q1 2025 — 11 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 843.84K | $244.72K | 0.00% | Hold |
| Renaissance Technologies history | 382.90K | $111.08K | 0.00% | Reduce |
| Geode Capital Management history | 276.71K | $80.29K | 0.00% | Add |
| BlackRock Inc history | 124.73K | $36.19K | 0.00% | Hold |
| UBS Group AG history | 116.46K | $33.77K | 0.00% | Add |
| Northern Trust Corp history | 32.72K | $9.49K | 0.00% | Reduce |
| Two Sigma Investments history | 20.55K | $5.96K | 0.00% | Hold |
| Citigroup Inc history | 11.08K | $3.21K | 0.00% | New |
| Morgan Stanley history | 7.40K | $2.15K | 0.00% | Add |
| Bank of America Corp history | 233 | $68 | 0.00% | Add |
| JPMorgan Chase & Co history | 65 | $19 | 0.00% | Reduce |
Q4 2024 — 10 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 843.84K | $354.42K | 0.00% | Hold |
| Renaissance Technologies history | 405.90K | $170.48K | 0.00% | Reduce |
| Geode Capital Management history | 273.79K | $115.01K | 0.00% | Add |
| BlackRock Inc history | 124.73K | $52.39K | 0.00% | Hold |
| UBS Group AG history | 86.05K | $36.14K | 0.00% | Add |
| Northern Trust Corp history | 80.31K | $33.73K | 0.00% | Add |
| Two Sigma Investments history | 20.62K | $8.66K | 0.00% | Reduce |
| Morgan Stanley history | 2.13K | $896 | 0.00% | Hold |
| Bank of America Corp history | 222 | $93 | 0.00% | Hold |
| JPMorgan Chase & Co history | 69 | $29 | 0.00% | Reduce |
New Positions (Q2 2026)
- Point72 Asset Management 28.28K sh · $1.53M
- Northern Trust Corp 21.08K sh · $1.14M
- BNY Mellon 6.78K sh · $366.06K
- Charles Schwab Investment Management 5.90K sh · $318.38K
- Renaissance Technologies 4.70K sh · $253.80K
- Deutsche Bank AG 2.65K sh · $143.21K
- Wells Fargo & Co 2.33K sh · $125.77K
- JPMorgan Chase & Co 1.13K sh · $62.98K
- Fidelity Management & Research (FMR) 343 sh · $18.52K
- Legal & General Investment Management America 264 sh · $14.22K
Fully Exited (vs previous quarter)
- Wellington Management Group sold 48.80K sh · $3.19M
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | 187.84K | 16.94K | 16.94K | — | 124.73K | 124.73K | 124.73K | — | — | — | — | — | — | — | — | — | — | — | — |
| Millennium Management | 160.98K | 111.89K | — | — | — | — | — | — | 102.22K | 510.44K | 583.47K | 577.66K | 608.85K | 147.50K | 145.01K | 190.15K | — | — | 38.62K |
| Geode Capital Management | 70.55K | 12.89K | 12.73K | — | 276.71K | 273.79K | 261.95K | 204.00K | 200.16K | 167.40K | 167.40K | 217.91K | 60.62K | 60.62K | 60.76K | 60.76K | 127.03K | 142.47K | 111.42K |
| Citadel Advisors | 51.91K | 70.00K | 70.00K | — | — | — | 80.35K | 146.81K | 120.98K | 108.24K | 75.03K | 71.28K | 1.70M | 1.75M | 1.73M | 1.72M | 1.72M | 1.73M | 1.70M |
| Goldman Sachs Group | 32.35K | 5.51K | — | — | — | — | — | — | — | — | — | — | 182.66K | — | 19.55K | 59.61K | 42.67K | 230.80K | 12.96K |
| Point72 Asset Management | 28.28K | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| UBS Group AG | 23.38K | 3.92K | 4.90K | 132 | 116.46K | 86.05K | 13 | 131.92K | 15.81K | 485 | 13 | 13 | 960 | 5.64K | 7.51K | 5.85K | 3.91K | 5.35K | — |
| Northern Trust Corp | 21.08K | — | 2.42K | — | 32.72K | 80.31K | 74.93K | 74.93K | 74.95K | 96.69K | 48.66K | 57.10K | 13.74K | 14.07K | 14.07K | 14.07K | 70.69K | 75.01K | 74.67K |
| Balyasny Asset Management | 12.14K | 40.00K | 40.00K | — | — | — | — | — | 22.51K | — | — | — | — | — | — | — | — | — | — |
| BNY Mellon | 6.78K | — | — | — | — | — | — | — | — | — | 89.12K | 91.45K | 92.08K | 92.08K | 92.76K | 92.76K | 116.50K | 27.89K | 27.45K |
| Charles Schwab Investment Management | 5.90K | — | — | — | — | — | — | 15.29K | 15.29K | 15.29K | 15.29K | 15.29K | — | — | — | — | 18.42K | 18.42K | 18.42K |
| Renaissance Technologies | 4.70K | — | — | — | 382.90K | 405.90K | 609.70K | 366.10K | 271.00K | 185.10K | 207.78K | 239.10K | 160.10K | 138.42K | 143.10K | 151.40K | 111.70K | 39.80K | 34.00K |
| Morgan Stanley | 4.41K | 1.42K | 388 | 98 | 7.40K | 2.13K | 2.13K | 2.13K | 21.52K | 2.13K | 2.13K | 2.13K | 3.15K | 3.34K | 23.17K | 60.66K | 11.42K | 12.39K | 75.91K |
| Deutsche Bank AG | 2.65K | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 12.30K | 5.28K | 5.00K |
| Wells Fargo & Co | 2.33K | — | — | — | — | — | — | — | 143 | 141 | 130 | 186 | 67 | 466 | 664 | 1.06K | 4.85K | 9.47K | 10.92K |
| Citigroup Inc | 1.26K | 939 | — | — | 11.08K | — | — | — | — | — | — | — | — | — | — | 393 | 1.19K | 2.21K | 1.38K |
| JPMorgan Chase & Co | 1.13K | — | — | — | 65 | 69 | 71 | 72 | 11 | 11 | 11 | 23.56K | 58.18K | 11 | 11 | 11 | 113.38K | 118.37K | 125.46K |
| Fidelity Management & Research (FMR) | 343 | — | — | — | — | — | — | — | 103 | — | 36 | — | 50 | — | 416 | 415 | 6.98K | 114.50K | 951.53K |
| Legal & General Investment Management America | 264 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 782 | 782 | 782 | 782 |
| Bank of America Corp | — | — | 93 | 3 | 233 | 222 | 223 | 150 | 26.13K | 13 | 310 | — | 249 | 11 | 1.32K | 2.85K | 4.91K | 83.10K | 16.82K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details