SAVA — CASSAVA SCIENCES INC
As of Q2 2026, 18 SEC-registered investment managers reported holding SAVA (CASSAVA SCIENCES INC) in their latest 13F filings, with a combined reported value of $8.77M across 7.41M shares. That is -5.7% by share count (-445.24K shares) versus the previous quarter, while reported value moved -33.7%. Ownership is concentrated: the five largest holders account for 82.1% of reported value and the top ten for 99.0%.
Compared with the prior quarter, 1 opened new positions, 7 added to existing stakes, 10 trimmed, 5 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 18 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Two Sigma Investments history | 1.71M | $2.04M | 0.00% | Reduce |
| Marshall Wace history | 1.60M | $1.90M | 0.00% | Reduce |
| BlackRock Inc history | 1.45M | $1.73M | 0.00% | Add |
| Goldman Sachs Group history | 668.79K | $795.86K | 0.00% | Add |
| Geode Capital Management history | 615.51K | $732.74K | 0.00% | Add |
| D. E. Shaw & Co history | 485.02K | $577.18K | 0.00% | Reduce |
| Renaissance Technologies history | 389.60K | $463.62K | 0.00% | Add |
| Citadel Advisors history | 218.10K | $259.54K | 0.00% | Reduce |
| Northern Trust Corp history | 114.32K | $136.04K | 0.00% | Reduce |
| UBS Group AG history | 39.06K | $46.48K | 0.00% | Add |
| BNY Mellon history | 20.28K | $24.14K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 17.03K | $20.78K | 0.00% | New |
| Morgan Stanley history | 13.56K | $16.14K | 0.00% | Reduce |
| Point72 Asset Management history | 11.57K | $13.77K | 0.00% | Reduce |
| Wells Fargo & Co history | 10.47K | $12.45K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 2.90K | $3.46K | 0.00% | Reduce |
| T. Rowe Price Associates history | 40.86K | $49 | 0.00% | Add |
| Citigroup Inc history | 19 | $23 | 0.00% | Reduce |
Q1 2026 — 22 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Marshall Wace history | 2.01M | $3.40M | 0.00% | Reduce |
| Two Sigma Investments history | 1.99M | $3.36M | 0.00% | Add |
| BlackRock Inc history | 1.41M | $2.39M | 0.00% | Hold |
| Geode Capital Management history | 596.24K | $1.01M | 0.00% | Add |
| D. E. Shaw & Co history | 559.21K | $945.06K | 0.00% | Add |
| Renaissance Technologies history | 326.76K | $552.22K | 0.00% | New |
| Citadel Advisors history | 311.10K | $525.76K | 0.00% | Reduce |
| CPP Investments history | 189.10K | $319.58K | 0.00% | Add |
| Northern Trust Corp history | 149.19K | $252.14K | 0.00% | Hold |
| Millennium Management history | 72.59K | $122.67K | 0.00% | Reduce |
| Goldman Sachs Group history | 41.32K | $69.84K | 0.00% | Add |
| Point72 Asset Management history | 39.12K | $66.11K | 0.00% | Reduce |
| Invesco Ltd history | 31.13K | $52.61K | 0.00% | Add |
| Charles Schwab Investment Management history | 25.56K | $43.20K | 0.00% | Reduce |
| BNY Mellon history | 20.48K | $34.61K | 0.00% | Hold |
| Morgan Stanley history | 17.99K | $30.40K | 0.00% | Reduce |
| UBS Group AG history | 11.60K | $19.61K | 0.00% | Reduce |
| Wells Fargo & Co history | 8.42K | $14.23K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 6.06K | $10.24K | 0.00% | Reduce |
| PNC Financial Services history | 1.68K | $2.84K | 0.00% | Reduce |
| T. Rowe Price Associates history | 31.37K | $54 | 0.00% | Hold |
| Citigroup Inc history | 20 | $34 | 0.00% | Reduce |
Q4 2025 — 24 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 2.38M | $4.70M | 0.00% | Add |
| Marshall Wace history | 2.12M | $4.19M | 0.00% | Add |
| BlackRock Inc history | 1.42M | $2.81M | 0.00% | Add |
| Two Sigma Investments history | 642.40K | $1.27M | 0.00% | Add |
| Geode Capital Management history | 545.97K | $1.08M | 0.00% | Add |
| Citadel Advisors history | 473.70K | $937.93K | 0.00% | Reduce |
| D. E. Shaw & Co history | 469.33K | $929.27K | 0.00% | New |
| Point72 Asset Management history | 299.58K | $593.17K | 0.00% | New |
| Millennium Management history | 274.40K | $543.31K | 0.00% | Reduce |
| Northern Trust Corp history | 149.19K | $295.40K | 0.00% | Add |
| CPP Investments history | 144.10K | $285.32K | 0.00% | New |
| Morgan Stanley history | 70.44K | $139.47K | 0.00% | Reduce |
| Goldman Sachs Group history | 32.99K | $65.32K | 0.00% | Reduce |
| UBS Group AG history | 29.87K | $59.14K | 0.00% | Reduce |
| Charles Schwab Investment Management history | 26.00K | $51.48K | 0.00% | Hold |
| BNY Mellon history | 20.48K | $40.55K | 0.00% | Add |
| Invesco Ltd history | 18.12K | $35.88K | 0.00% | New |
| Wells Fargo & Co history | 16.30K | $32.28K | 0.00% | Reduce |
| Bank of America Corp history | 13.53K | $26.79K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 7.49K | $14.83K | 0.00% | Reduce |
| PNC Financial Services history | 1.73K | $3.43K | 0.00% | Hold |
| Citigroup Inc history | 62 | $123 | 0.00% | Reduce |
| T. Rowe Price Associates history | 31.37K | $63 | 0.00% | New |
| JPMorgan Chase & Co history | 13 | $26 | 0.00% | Reduce |
Q3 2025 — 19 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 2.29M | $6.66M | 0.00% | Add |
| Marshall Wace history | 2.06M | $6.00M | 0.01% | Add |
| BlackRock Inc history | 1.41M | $4.10M | 0.00% | Reduce |
| JPMorgan Chase & Co history | 565.44K | $1.65M | 0.00% | Reduce |
| Two Sigma Investments history | 565.00K | $1.64M | 0.00% | Add |
| Geode Capital Management history | 537.90K | $1.57M | 0.00% | Add |
| Citadel Advisors history | 480.26K | $1.40M | 0.00% | Add |
| Goldman Sachs Group history | 472.86K | $1.38M | 0.00% | Reduce |
| Morgan Stanley history | 350.06K | $1.02M | 0.00% | Reduce |
| Millennium Management history | 318.89K | $927.96K | 0.00% | Reduce |
| UBS Group AG history | 188.99K | $549.97K | 0.00% | Reduce |
| Northern Trust Corp history | 131.17K | $381.70K | 0.00% | Add |
| Bank of America Corp history | 67.23K | $195.63K | 0.00% | Reduce |
| Charles Schwab Investment Management history | 26.05K | $75.80K | 0.00% | Reduce |
| Wells Fargo & Co history | 19.88K | $57.86K | 0.00% | Reduce |
| BNY Mellon history | 10.66K | $31.03K | 0.00% | Hold |
| Fidelity Management & Research (FMR) history | 8.64K | $25.14K | 0.00% | Add |
| Citigroup Inc history | 2.44K | $7.09K | 0.00% | Reduce |
| PNC Financial Services history | 1.73K | $5.04K | 0.00% | Reduce |
Q2 2025 — 21 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 2.17M | $3.93M | 0.00% | Reduce |
| BlackRock Inc history | 1.55M | $2.80M | 0.00% | Reduce |
| JPMorgan Chase & Co history | 757.06K | $1.37M | 0.00% | Reduce |
| Goldman Sachs Group history | 613.14K | $1.11M | 0.00% | Add |
| Two Sigma Investments history | 526.51K | $952.99K | 0.00% | Add |
| Geode Capital Management history | 522.88K | $946.78K | 0.00% | Reduce |
| Millennium Management history | 472.78K | $855.74K | 0.00% | New |
| Morgan Stanley history | 450.55K | $815.49K | 0.00% | Add |
| Charles Schwab Investment Management history | 265.29K | $480.18K | 0.00% | Reduce |
| Citadel Advisors history | 245.00K | $443.45K | 0.00% | Reduce |
| UBS Group AG history | 190.09K | $344.05K | 0.00% | Reduce |
| Northern Trust Corp history | 101.67K | $184.03K | 0.00% | Reduce |
| Marshall Wace history | 71.71K | $129.80K | 0.00% | New |
| Bank of America Corp history | 68.40K | $123.81K | 0.00% | Reduce |
| AQR Capital Management history | 29.78K | $53.91K | 0.00% | Reduce |
| Wells Fargo & Co history | 23.38K | $42.32K | 0.00% | Reduce |
| Citigroup Inc history | 21.04K | $38.08K | 0.00% | Reduce |
| BNY Mellon history | 10.66K | $19.30K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 8.58K | $15.52K | 0.00% | Reduce |
| PNC Financial Services history | 2.21K | $4.01K | 0.00% | Reduce |
| T. Rowe Price Associates history | 35.87K | $65 | 0.00% | Add |
Q1 2025 — 23 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 3.47M | $5.21M | 0.00% | Reduce |
| Vanguard Group history | 2.44M | $3.66M | 0.00% | Reduce |
| Geode Capital Management history | 1.03M | $1.54M | 0.00% | Add |
| JPMorgan Chase & Co history | 790.02K | $1.19M | 0.00% | Add |
| UBS Group AG history | 545.82K | $818.72K | 0.00% | Reduce |
| Goldman Sachs Group history | 496.31K | $744.47K | 0.00% | Add |
| Citadel Advisors history | 473.87K | $710.81K | 0.00% | Reduce |
| Two Sigma Investments history | 432.58K | $648.87K | 0.00% | Reduce |
| Morgan Stanley history | 376.35K | $564.53K | 0.00% | Add |
| Northern Trust Corp history | 369.09K | $553.64K | 0.00% | Reduce |
| Charles Schwab Investment Management history | 361.25K | $541.88K | 0.00% | Add |
| Bank of America Corp history | 122.12K | $183.18K | 0.00% | Reduce |
| BNY Mellon history | 110.66K | $165.99K | 0.00% | Hold |
| AQR Capital Management history | 79.94K | $119.92K | 0.00% | New |
| Deutsche Bank AG history | 34.62K | $51.92K | 0.00% | Reduce |
| Citigroup Inc history | 30.89K | $46.34K | 0.00% | Reduce |
| Wells Fargo & Co history | 25.62K | $38.43K | 0.00% | Reduce |
| Manulife Financial history | 14.00K | $21.00K | 0.00% | Reduce |
| Invesco Ltd history | 13.12K | $19.68K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 10.99K | $16.49K | 0.00% | Reduce |
| Legal & General Investment Management America history | 7.26K | $10.91K | 0.00% | Reduce |
| PNC Financial Services history | 2.32K | $3.48K | 0.00% | Add |
| T. Rowe Price Associates history | 31.43K | $48 | 0.00% | Reduce |
New Positions (Q2 2026)
- JPMorgan Chase & Co 17.03K sh · $20.78K
Fully Exited (vs previous quarter)
- CPP Investments sold 189.10K sh · $319.58K
- Millennium Management sold 72.59K sh · $122.67K
- Invesco Ltd sold 31.13K sh · $52.61K
- Charles Schwab Investment Management sold 25.56K sh · $43.20K
- PNC Financial Services sold 1.68K sh · $2.84K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Two Sigma Investments | 1.71M | 1.99M | 642.40K | 565.00K | 526.51K | 432.58K | 562.08K | 72.15K | 18.75K | — | — | — | — | — | — | — | — | — | — | — |
| Marshall Wace | 1.60M | 2.01M | 2.12M | 2.06M | 71.71K | — | 21.09K | — | — | — | — | — | 24.35K | — | — | 157.32K | — | — | — | — |
| BlackRock Inc | 1.45M | 1.41M | 1.42M | 1.41M | 1.55M | 3.47M | 3.74M | 3.26M | — | — | — | — | — | — | — | — | — | — | — | — |
| Goldman Sachs Group | 668.79K | 41.32K | 32.99K | 472.86K | 613.14K | 496.31K | 278.91K | 152.94K | 103.05K | 52.83K | 161.66K | 53.20K | 65.52K | 63.51K | 159.25K | 76.80K | 37.56K | 39.20K | 54.91K | 51.96K |
| Geode Capital Management | 615.51K | 596.24K | 545.97K | 537.90K | 522.88K | 1.03M | 1.01M | 1.01M | 967.30K | 901.84K | 874.00K | 830.25K | 803.31K | 758.96K | 708.79K | 684.85K | 673.54K | 645.85K | 636.42K | 638.47K |
| D. E. Shaw & Co | 485.02K | 559.21K | 469.33K | — | — | — | — | — | — | — | — | 16.55K | 13.14K | — | 10.00K | 10.00K | 10.00K | 54.40K | 10.00K | 59.27K |
| Renaissance Technologies | 389.60K | 326.76K | — | — | — | — | — | 81.10K | — | — | — | — | — | — | — | — | — | — | — | — |
| Citadel Advisors | 218.10K | 311.10K | 473.70K | 480.26K | 245.00K | 473.87K | 690.90K | 1.02M | 203.34K | 130.00K | 508.30K | 717.30K | 858.61K | 1.11M | 1.24M | 1.70M | 1.57M | 1.40M | 1.59M | 1.77M |
| Northern Trust Corp | 114.32K | 149.19K | 149.19K | 131.17K | 101.67K | 369.09K | 406.56K | 395.78K | 378.34K | 378.82K | 387.67K | 373.63K | 370.64K | 360.42K | 352.54K | 352.94K | 358.35K | 364.49K | 379.83K | 380.65K |
| UBS Group AG | 39.06K | 11.60K | 29.87K | 188.99K | 190.09K | 545.82K | 930.73K | 88.87K | 63.01K | 84.73K | 83.84K | 27.67K | 63.80K | 58.20K | 60.95K | 109.95K | 24.26K | 25.18K | 33.14K | 60.31K |
| BNY Mellon | 20.28K | 20.48K | 20.48K | 10.66K | 10.66K | 110.66K | 110.79K | 107.84K | 140.85K | 119.29K | 132.42K | 135.10K | 131.37K | 127.28K | 129.65K | 128.79K | 116.39K | 122.99K | 122.28K | 123.55K |
| JPMorgan Chase & Co | 17.03K | — | 13 | 565.44K | 757.06K | 790.02K | 401.33K | 36.35K | 55.88K | 55.87K | 55.13K | 49.20K | 55.62K | 1.18K | 39.37K | 35.13K | 55.87K | 28.72K | 24.59K | 23.05K |
| Morgan Stanley | 13.56K | 17.99K | 70.44K | 350.06K | 450.55K | 376.35K | 266.19K | 519.54K | 163.33K | 204.42K | 541.27K | 433.24K | 171.15K | 152.45K | 215.44K | 217.94K | 216.50K | 147.68K | 554.69K | 354.47K |
| Point72 Asset Management | 11.57K | 39.12K | 299.58K | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Wells Fargo & Co | 10.47K | 8.42K | 16.30K | 19.88K | 23.38K | 25.62K | 30.00K | 25.96K | 17.55K | 16.35K | 14.18K | 12.54K | 20.18K | 10.59K | 3.22K | 13.58K | 2.29K | 10.07K | 40.30K | 25.48K |
| Fidelity Management & Research (FMR) | 2.90K | 6.06K | 7.49K | 8.64K | 8.58K | 10.99K | 91.15K | 1.12K | 1.36K | 11.79K | 2.04K | 5.02K | 2.14K | 1.67K | 4.65K | 4.96K | 570 | 610 | — | — |
| T. Rowe Price Associates | 40.86K | 31.37K | 31.37K | — | 35.87K | 31.43K | 36.37K | 35.33K | 34.78K | 31.33K | 29.87K | 27.59K | 26.72K | 26.97K | 25.40K | 27.78K | 26.85K | 28.25K | 22.90K | 21.26K |
| Citigroup Inc | 19 | 20 | 62 | 2.44K | 21.04K | 30.89K | 42.55K | 147.86K | 18.34K | 21.82K | 124.96K | 13.87K | 23.38K | 15.38K | 13.33K | 14.80K | 19.29K | 15.79K | 22.78K | 38.90K |
| CPP Investments | — | 189.10K | 144.10K | — | — | — | 4.50K | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Bank of America Corp | — | — | 13.53K | 67.23K | 68.40K | 122.12K | 1.24M | 838.45K | 312.79K | 287.81K | 345.14K | 1.41M | 373.61K | 418.67K | 179.83K | 611.00K | 259.45K | 29.84K | 475.11K | 251.67K |