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PYXS — PYXIS ONCOLOGY INC

Reported value held$21.69M
Funds holding (latest)34
SectorHealth Care
Funds holding (Q2 2026)19
Institutional value$12.39M · 4.11M sh
New / Add / Cut / Exit1 / 8 / 7 / 1
Top-5 / Top-10 concentration80.1% / 94.1%
Institutional holdings change Accumulating +5.3% (+208.53K sh)
Institutional value change Up +117.2%

As of Q2 2026, 19 SEC-registered investment managers reported holding PYXS (PYXIS ONCOLOGY INC) in their latest 13F filings, with a combined reported value of $12.39M across 4.11M shares. That is +5.3% by share count (+208.53K shares) versus the previous quarter, while reported value moved +117.2%. Ownership is concentrated: the five largest holders account for 80.1% of reported value and the top ten for 94.1%.

Compared with the prior quarter, 1 opened new positions, 8 added to existing stakes, 7 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

PYXS is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 19 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 867.93K $2.61M 0.00% Add
Marshall Wace history 830.54K $2.50M 0.00% Add
Renaissance Technologies history 772.23K $2.32M 0.00% Reduce
Geode Capital Management history 591.85K $1.78M 0.00% Reduce
Millennium Management history 233.00K $701.34K 0.00% Reduce
UBS Group AG history 155.22K $467.20K 0.00% Reduce
BNY Mellon history 134.00K $403.33K 0.00% Hold
Northern Trust Corp history 123.96K $373.12K 0.00% Add
Two Sigma Investments history 83.96K $252.72K 0.00% Add
Bank of America Corp history 80.46K $242.20K 0.00% Add
Citadel Advisors history 62.02K $186.67K 0.00% Reduce
Goldman Sachs Group history 45.90K $138.16K 0.00% Reduce
Citigroup Inc history 38.20K $115.00K 0.00% Add
Point72 Asset Management history 37.09K $111.65K 0.00% Add
Morgan Stanley history 33.45K $100.68K 0.00% Reduce
Fidelity Management & Research (FMR) history 12.38K $37.27K 0.00% Add
PNC Financial Services history 6.50K $19.57K 0.00% Hold
JPMorgan Chase & Co history 5.54K $15.86K 0.00% New
Wells Fargo & Co history 285 $858 0.00% Hold

Q1 2026 — 19 funds

FundSharesValuePortfolio WeightChange
Renaissance Technologies history 888.68K $1.30M 0.00% Add
BlackRock Inc history 788.84K $1.15M 0.00% Add
Geode Capital Management history 598.12K $873.82K 0.00% Add
Millennium Management history 397.62K $580.53K 0.00% Reduce
Marshall Wace history 354.42K $517.45K 0.00% Reduce
UBS Group AG history 254.12K $371.02K 0.00% Reduce
BNY Mellon history 134.00K $195.63K 0.00% Reduce
Citadel Advisors history 128.35K $187.39K 0.00% Reduce
Northern Trust Corp history 101.95K $148.84K 0.00% Hold
Two Sigma Investments history 73.30K $107.02K 0.00% Reduce
Morgan Stanley history 69.69K $101.74K 0.00% Reduce
Goldman Sachs Group history 46.92K $68.50K 0.00% Reduce
Point72 Asset Management history 32.01K $46.73K 0.00% Reduce
Bank of America Corp history 16.81K $24.54K 0.00% Reduce
Fidelity Management & Research (FMR) history 11.91K $17.39K 0.00% Reduce
PNC Financial Services history 6.50K $9.49K 0.00% New
Citigroup Inc history 1.74K $2.54K 0.00% Reduce
Balyasny Asset Management history 743 $1.08K 0.00% Reduce
Wells Fargo & Co history 285 $416 0.00% Reduce

Q4 2025 — 20 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 2.34M $2.69M 0.00% Add
BlackRock Inc history 784.08K $901.69K 0.00% Add
Millennium Management history 743.11K $854.57K 0.00% Reduce
Renaissance Technologies history 728.38K $837.64K 0.00% Add
Bank of America Corp history 587.85K $676.03K 0.00% Reduce
Geode Capital Management history 577.21K $664.21K 0.00% Add
UBS Group AG history 392.77K $451.68K 0.00% Add
Marshall Wace history 389.76K $448.23K 0.00% New
Citadel Advisors history 378.19K $434.92K 0.00% Add
Point72 Asset Management history 188.14K $216.36K 0.00% New
BNY Mellon history 165.04K $189.80K 0.00% Hold
Two Sigma Investments history 105.53K $121.36K 0.00% Add
Northern Trust Corp history 101.95K $117.24K 0.00% Add
Morgan Stanley history 89.22K $102.61K 0.00% Reduce
Goldman Sachs Group history 86.14K $99.07K 0.00% Reduce
Fidelity Management & Research (FMR) history 12.86K $14.79K 0.00% Reduce
Balyasny Asset Management history 8.23K $9.46K 0.00% New
JPMorgan Chase & Co history 5.51K $6.34K 0.00% Add
Citigroup Inc history 2.90K $3.34K 0.00% Add
Wells Fargo & Co history 2.29K $2.63K 0.00% Add

Q3 2025 — 19 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 2.16M $4.80M 0.00% Add
Millennium Management history 815.33K $1.81M 0.00% Reduce
BlackRock Inc history 683.70K $1.52M 0.00% Reduce
Bank of America Corp history 615.92K $1.37M 0.00% Add
Renaissance Technologies history 576.34K $1.28M 0.00% Add
Geode Capital Management history 544.51K $1.21M 0.00% Add
UBS Group AG history 373.73K $829.67K 0.00% Reduce
Citadel Advisors history 337.36K $748.94K 0.00% New
BNY Mellon history 165.04K $366.40K 0.00% Hold
Goldman Sachs Group history 125.45K $278.51K 0.00% Reduce
Morgan Stanley history 106.61K $236.67K 0.00% Reduce
Northern Trust Corp history 100.77K $223.72K 0.00% Reduce
Two Sigma Investments history 46.50K $103.23K 0.00% New
Prudential Financial history 16.30K $36.19K 0.00% New
Fidelity Management & Research (FMR) history 15.46K $34.31K 0.00% Reduce
AQR Capital Management history 13.83K $30.71K 0.00% Reduce
JPMorgan Chase & Co history 4.51K $10.02K 0.00% Add
Citigroup Inc history 1.28K $2.84K 0.00% Reduce
Wells Fargo & Co history 285 $633 0.00% Reduce

Q2 2025 — 17 funds

FundSharesValuePortfolio WeightChange
Millennium Management history 3.54M $3.89M 0.00% Add
Vanguard Group history 2.15M $2.36M 0.00% Reduce
BlackRock Inc history 926.80K $1.02M 0.00% Reduce
Geode Capital Management history 510.96K $562.25K 0.00% Reduce
Renaissance Technologies history 417.82K $459.60K 0.00% Reduce
UBS Group AG history 396.10K $435.71K 0.00% Hold
Goldman Sachs Group history 224.27K $246.70K 0.00% Add
BNY Mellon history 165.04K $181.55K 0.00% Reduce
Morgan Stanley history 160.17K $176.19K 0.00% Reduce
Marshall Wace history 147.77K $162.55K 0.00% New
Northern Trust Corp history 102.22K $112.44K 0.00% Reduce
Fidelity Management & Research (FMR) history 94.85K $104.33K 0.00% Add
AQR Capital Management history 86.76K $95.44K 0.00% Add
Bank of America Corp history 22.07K $24.28K 0.00% Reduce
Citigroup Inc history 8.93K $9.82K 0.00% Reduce
JPMorgan Chase & Co history 2.07K $2.27K 0.00% Reduce
Wells Fargo & Co history 699 $769 0.00% Reduce

Q1 2025 — 22 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.27M $3.21M 0.00% Reduce
Millennium Management history 2.49M $2.44M 0.00% Reduce
Vanguard Group history 2.44M $2.39M 0.00% Hold
Geode Capital Management history 1.11M $1.09M 0.00% Add
Renaissance Technologies history 582.14K $570.43K 0.00% Add
Morgan Stanley history 446.48K $437.51K 0.00% Add
UBS Group AG history 396.84K $388.91K 0.00% Reduce
Northern Trust Corp history 373.72K $366.20K 0.00% Reduce
BNY Mellon history 272.77K $267.29K 0.00% Hold
Goldman Sachs Group history 160.83K $157.60K 0.00% Reduce
Charles Schwab Investment Management history 115.24K $112.92K 0.00% Reduce
Fidelity Management & Research (FMR) history 86.66K $84.91K 0.00% Add
Citadel Advisors history 50.40K $49.39K 0.00% Reduce
Bank of America Corp history 40.32K $39.48K 0.00% Reduce
AQR Capital Management history 40.27K $39.46K 0.00% Reduce
Citigroup Inc history 35.04K $34.34K 0.00% Reduce
Wells Fargo & Co history 29.89K $29.29K 0.00% Add
Deutsche Bank AG history 28.39K $27.82K 0.00% Reduce
JPMorgan Chase & Co history 28.14K $27.57K 0.00% Add
Invesco Ltd history 24.80K $24.31K 0.00% Reduce
Legal & General Investment Management America history 4.22K $4.13K 0.00% Hold
T. Rowe Price Associates history 22.22K $23 0.00% Add

View all 34 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021
BlackRock Inc 867.93K 788.84K 784.08K 683.70K 926.80K 3.27M 3.34M 2.96M — — — — — — — — — — —
Marshall Wace 830.54K 354.42K 389.76K — 147.77K — 157.95K 116.36K 10.00K 133.58K — — — — — — — — —
Renaissance Technologies 772.23K 888.68K 728.38K 576.34K 417.82K 582.14K 293.35K 160.34K 96.94K 148.00K 364.15K 216.25K 253.23K 94.20K 83.60K 128.80K 75.37K — —
Geode Capital Management 591.85K 598.12K 577.21K 544.51K 510.96K 1.11M 1.08M 1.08M 1.03M 340.12K 308.24K 288.30K 242.79K 239.35K 203.93K 188.82K 109.85K 194.58K 181.47K
Millennium Management 233.00K 397.62K 743.11K 815.33K 3.54M 2.49M 2.98M 1.97M 1.34M 657.41K 13.27K — 30.88K — 31.33K 89.84K 142.81K — 10.25K
UBS Group AG 155.22K 254.12K 392.77K 373.73K 396.10K 396.84K 446.70K 28.10K 17.68K 28.25K 2.96K 2.96K 7.65K 2.96K — 155 367 1.43K 4.82K
BNY Mellon 134.00K 134.00K 165.04K 165.04K 165.04K 272.77K 272.77K 272.77K 311.63K 162.11K 16.13K 16.13K 14.48K 13.77K — — — 32.59K 19.28K
Northern Trust Corp 123.96K 101.95K 101.95K 100.77K 102.22K 373.72K 378.59K 394.04K 128.40K 61.23K 60.28K 52.75K 47.39K 31.51K 26.40K 26.40K 17.74K 88.33K 89.23K
Two Sigma Investments 83.96K 73.30K 105.53K 46.50K — — 17.07K 24.58K 95.70K — 91.56K 119.81K 108.41K — 35.48K 37.68K 42.30K — —
Bank of America Corp 80.46K 16.81K 587.85K 615.92K 22.07K 40.32K 53.74K 44.68K 44.78K 29.71K 19.84K 100.85K 130.68K 23.49K 63.59K 20.09K 15.73K 20.28K 28.62K
Citadel Advisors 62.02K 128.35K 378.19K 337.36K — 50.40K 84.10K 310.85K 14.00K 30.41K 110.03K — — 27.13K 1.56M 1.53M 1.52M 1.52M 1.52M
Goldman Sachs Group 45.90K 46.92K 86.14K 125.45K 224.27K 160.83K 184.70K 139.13K 117.25K 336.69K — — 45.97K 35.42K — — 12.88K — —
Citigroup Inc 38.20K 1.74K 2.90K 1.28K 8.93K 35.04K 42.09K 35.58K 10.96K 44.70K — — — — 357.54K 312.31K 312.41K 233.13K 3.21K
Point72 Asset Management 37.09K 32.01K 188.14K — — — — — — — — — — 251.80K — — — — —
Morgan Stanley 33.45K 69.69K 89.22K 106.61K 160.17K 446.48K 242.73K 153.25K 82.61K 43.53K 3.20K 3.20K 500 168.58K 106.42K 122.00K 136.88K 3.19K 2.83K
Fidelity Management & Research (FMR) 12.38K 11.91K 12.86K 15.46K 94.85K 86.66K 84.89K 3.97K — 1 — 346 171 — — 855 858 129 —
PNC Financial Services 6.50K 6.50K — — — — — — — — — — 100 100 — — — — —
JPMorgan Chase & Co 5.54K — 5.51K 4.51K 2.07K 28.14K 27.08K 21.98K 21.31K 500 500 500 4.31K 5.03K — — — 4.99K 11.77K
Wells Fargo & Co 285 285 2.29K 285 699 29.89K 28.95K 24.23K 22.04K 834 2.53K 2.51K 2.47K 2.16K 160 146 70 5.32K 11.41K
AQR Capital Management — — — 13.83K 86.76K 40.27K 50.08K — — — — — — — — — — — —

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