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PRTA — PROTHENA CORP PLC

Reported value held$238.68M
Funds holding (latest)40
SectorHealth Care
Funds holding (Q2 2026)29
Institutional value$209.08M · 21.46M sh
New / Add / Cut / Exit2 / 17 / 8 / 1
Top-5 / Top-10 concentration75.2% / 91.6%
Institutional holdings change Reducing -3.2% (-718.57K sh)
Institutional value change Down -2.6%

As of Q2 2026, 29 SEC-registered investment managers reported holding PRTA (PROTHENA CORP PLC) in their latest 13F filings, with a combined reported value of $209.08M across 21.46M shares. That is -3.2% by share count (-718.57K shares) versus the previous quarter, while reported value moved -2.6%. Ownership is concentrated: the five largest holders account for 75.2% of reported value and the top ten for 91.6%.

Compared with the prior quarter, 2 opened new positions, 17 added to existing stakes, 8 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

PRTA is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 29 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 7.20M $70.48M 0.00% Reduce
BlackRock Inc history 4.87M $47.66M 0.00% Add
D. E. Shaw & Co history 1.61M $15.78M 0.01% Reduce
Two Sigma Investments history 1.26M $12.38M 0.01% Add
Geode Capital Management history 1.13M $11.02M 0.00% Add
Morgan Stanley history 995.35K $9.74M 0.00% Reduce
Goldman Sachs Group history 979.73K $9.59M 0.00% Add
Renaissance Technologies history 697.62K $6.83M 0.01% Add
Northern Trust Corp history 457.12K $4.48M 0.00% Add
Charles Schwab Investment Management history 355.90K $3.48M 0.00% Hold
AQR Capital Management history 302.57K $2.96M 0.00% Add
UBS Group AG history 241.43K $2.36M 0.00% Reduce
Bank of America Corp history 208.25K $2.04M 0.00% Reduce
Marshall Wace history 190.83K $1.87M 0.00% Add
Millennium Management history 149.90K $1.47M 0.00% Add
BNY Mellon history 133.91K $1.31M 0.00% Reduce
MFS Investment Management history 126.99K $1.24M 0.00% Reduce
Citadel Advisors history 116.90K $1.14M 0.00% Reduce
Invesco Ltd history 71.48K $699.78K 0.00% Add
Citigroup Inc history 57.83K $566.13K 0.00% Add
Wells Fargo & Co history 49.52K $484.80K 0.00% Add
Deutsche Bank AG history 43.27K $423.61K 0.00% Add
PNC Financial Services history 28.39K $277.90K 0.00% Hold
JPMorgan Chase & Co history 26.62K $265.40K 0.00% New
CPP Investments history 24.00K $234.96K 0.00% New
Manulife Financial history 12.63K $123.70K 0.00% Add
Prudential Financial history 11.39K $111.56K 0.00% Add
Legal & General Investment Management America history 4.51K $44.17K 0.00% Add
T. Rowe Price Associates history 109.25K $1.07K 0.00% Add

Q1 2026 — 28 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 7.55M $73.40M 0.00% Hold
BlackRock Inc history 4.64M $45.14M 0.00% Add
D. E. Shaw & Co history 1.76M $17.14M 0.01% Add
Morgan Stanley history 1.23M $11.96M 0.00% Reduce
Two Sigma Investments history 1.21M $11.72M 0.01% Add
Geode Capital Management history 1.10M $10.68M 0.00% Add
Goldman Sachs Group history 818.88K $7.96M 0.00% Reduce
Renaissance Technologies history 607.51K $5.91M 0.01% Add
Citadel Advisors history 572.77K $5.57M 0.00% Reduce
Point72 Asset Management history 399.83K $3.89M 0.01% Reduce
Bank of America Corp history 393.63K $3.83M 0.00% Reduce
Northern Trust Corp history 369.54K $3.59M 0.00% Add
Charles Schwab Investment Management history 356.67K $3.47M 0.00% Hold
UBS Group AG history 328.49K $3.19M 0.00% Reduce
AQR Capital Management history 204.02K $1.98M 0.00% Add
BNY Mellon history 136.32K $1.33M 0.00% Add
MFS Investment Management history 132.05K $1.28M 0.00% Add
Millennium Management history 50.30K $488.92K 0.00% Reduce
Invesco Ltd history 49.81K $484.13K 0.00% Add
Marshall Wace history 44.57K $433.26K 0.00% Reduce
Deutsche Bank AG history 40.02K $388.98K 0.00% Add
PNC Financial Services history 28.39K $275.91K 0.00% Add
Wells Fargo & Co history 27.34K $265.71K 0.00% Reduce
Manulife Financial history 12.18K $118.43K 0.00% Reduce
Prudential Financial history 10.03K $97.44K 0.00% New
Citigroup Inc history 8.15K $79.22K 0.00% Reduce
Legal & General Investment Management America history 3.97K $38.62K 0.00% Reduce
T. Rowe Price Associates history 95.65K $930 0.00% Add

Q4 2025 — 32 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 7.55M $72.11M 0.00% Reduce
BlackRock Inc history 4.11M $39.23M 0.00% Add
Vanguard Group history 2.14M $20.45M 0.00% Add
D. E. Shaw & Co history 1.68M $16.06M 0.01% Add
Morgan Stanley history 1.25M $11.91M 0.00% Add
Citadel Advisors history 1.08M $10.28M 0.00% Add
Geode Capital Management history 1.06M $10.15M 0.00% Add
Goldman Sachs Group history 935.33K $8.93M 0.00% Add
Point72 Asset Management history 919.42K $8.78M 0.01% Add
Two Sigma Investments history 670.14K $6.40M 0.01% Add
Renaissance Technologies history 435.51K $4.16M 0.01% Add
Bank of America Corp history 427.36K $4.08M 0.00% Add
UBS Group AG history 426.36K $4.07M 0.00% Add
Northern Trust Corp history 363.24K $3.47M 0.00% Add
Charles Schwab Investment Management history 357.33K $3.41M 0.00% Add
Arrowstreet Capital history 298.10K $2.85M 0.00% Reduce
AQR Capital Management history 186.78K $1.78M 0.00% Reduce
JPMorgan Chase & Co history 169.96K $1.62M 0.00% Reduce
BNY Mellon history 132.70K $1.27M 0.00% Reduce
Millennium Management history 99.38K $949.04K 0.00% Reduce
Wells Fargo & Co history 60.11K $574.03K 0.00% Add
Marshall Wace history 54.78K $523.13K 0.00% New
Franklin Resources history 47.25K $451.25K 0.00% Reduce
MFS Investment Management history 45.97K $439.01K 0.00% Reduce
Deutsche Bank AG history 35.48K $338.85K 0.00% Add
PNC Financial Services history 28.13K $268.62K 0.00% Add
Invesco Ltd history 26.61K $254.12K 0.00% Reduce
Manulife Financial history 13.70K $130.79K 0.00% Reduce
Citigroup Inc history 12.32K $117.64K 0.00% Add
CPP Investments history 7.10K $67.81K 0.00% New
Legal & General Investment Management America history 4.04K $38.62K 0.00% Add
T. Rowe Price Associates history 81.52K $779 0.00% Add

Q3 2025 — 31 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 7.90M $77.12M 0.00% Hold
BlackRock Inc history 3.60M $35.12M 0.00% Reduce
Vanguard Group history 2.05M $20.01M 0.00% Reduce
D. E. Shaw & Co history 1.32M $12.84M 0.01% Add
Geode Capital Management history 1.02M $9.95M 0.00% Add
Citadel Advisors history 971.71K $9.48M 0.00% Reduce
Morgan Stanley history 799.67K $7.80M 0.00% Reduce
JPMorgan Chase & Co history 735.76K $7.18M 0.00% Add
Arrowstreet Capital history 654.29K $6.39M 0.00% New
Point72 Asset Management history 646.75K $6.31M 0.01% New
Millennium Management history 621.10K $6.06M 0.00% Add
Two Sigma Investments history 426.61K $4.16M 0.01% Add
UBS Group AG history 400.85K $3.91M 0.00% Add
Renaissance Technologies history 371.30K $3.62M 0.01% Add
Goldman Sachs Group history 353.22K $3.45M 0.00% Reduce
Charles Schwab Investment Management history 350.82K $3.42M 0.00% Add
Northern Trust Corp history 334.66K $3.27M 0.00% Hold
Bank of America Corp history 277.10K $2.70M 0.00% Add
AQR Capital Management history 214.54K $2.09M 0.00% New
BNY Mellon history 153.80K $1.50M 0.00% Add
Franklin Resources history 61.17K $597.04K 0.00% Add
Balyasny Asset Management history 55.76K $544.26K 0.00% Reduce
MFS Investment Management history 47.49K $463.49K 0.00% Add
Wells Fargo & Co history 40.43K $394.60K 0.00% Reduce
Deutsche Bank AG history 33.77K $329.62K 0.00% Reduce
Invesco Ltd history 31.30K $305.52K 0.00% Reduce
PNC Financial Services history 18.14K $177.02K 0.00% Add
Manulife Financial history 13.87K $135.34K 0.00% Reduce
Legal & General Investment Management America history 3.60K $35.13K 0.00% Reduce
Citigroup Inc history 3.59K $35.06K 0.00% Reduce
T. Rowe Price Associates history 78.55K $767 0.00% Add

Q2 2025 — 41 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 7.90M $47.96M 0.00% Reduce
Fidelity Management & Research (FMR) history 7.90M $47.96M 0.00% Reduce
BlackRock Inc history 3.94M $23.91M 0.00% Reduce
BlackRock Inc history 3.94M $23.91M 0.00% Reduce
Vanguard Group history 2.18M $13.21M 0.00% Add
Citadel Advisors history 1.37M $8.32M 0.00% Add
Citadel Advisors history 1.37M $8.32M 0.00% Add
Morgan Stanley history 953.26K $5.79M 0.00% Add
Morgan Stanley history 953.26K $5.79M 0.00% Add
Geode Capital Management history 933.45K $5.67M 0.00% Reduce
Balyasny Asset Management history 575.79K $3.50M 0.01% New
Goldman Sachs Group history 528.32K $3.21M 0.00% Add
Goldman Sachs Group history 528.32K $3.21M 0.00% Add
D. E. Shaw & Co history 391.50K $2.38M 0.00% Add
Northern Trust Corp history 334.55K $2.03M 0.00% Reduce
Charles Schwab Investment Management history 275.08K $1.67M 0.00% Reduce
Bank of America Corp history 210.94K $1.28M 0.00% Add
Two Sigma Investments history 201.45K $1.22M 0.00% Add
Two Sigma Investments history 201.45K $1.22M 0.00% Add
Millennium Management history 170.58K $1.04M 0.00% Add
BNY Mellon history 148.35K $900.49K 0.00% Add
JPMorgan Chase & Co history 126.95K $770.59K 0.00% Reduce
JPMorgan Chase & Co history 126.95K $770.59K 0.00% Reduce
Wellington Management Group history 107.84K $654.58K 0.00% Reduce
Renaissance Technologies history 90.20K $547.51K 0.00% Reduce
Renaissance Technologies history 90.20K $547.51K 0.00% Reduce
UBS Group AG history 60.66K $368.23K 0.00% Reduce
Norges Bank Investment Management history 57.45K $348.75K 0.00% Hold
Norges Bank Investment Management history 57.45K $348.75K 0.00% Hold
Franklin Resources history 56.08K $340.39K 0.00% Add
Citigroup Inc history 49.30K $299.27K 0.00% Reduce
MFS Investment Management history 44.36K $269.29K 0.00% Add
Wells Fargo & Co history 41.22K $250.20K 0.00% Reduce
Deutsche Bank AG history 39.60K $240.38K 0.00% Reduce
Deutsche Bank AG history 39.60K $240.38K 0.00% Reduce
Invesco Ltd history 36.88K $223.89K 0.00% Reduce
Janus Henderson Group history 18.05K $109.82K 0.00% Hold
PNC Financial Services history 18.03K $109.43K 0.00% Add
Manulife Financial history 15.14K $91.90K 0.00% Reduce
Legal & General Investment Management America history 9.32K $56.59K 0.00% Reduce
T. Rowe Price Associates history 71.05K $432 0.00% Reduce

Q1 2025 — 39 funds

FundSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history 7.94M $98.27M 0.01% Reduce
Fidelity Management & Research (FMR) history 7.94M $98.27M 0.01% Reduce
Wellington Management Group history 5.20M $64.34M 0.01% Add
BlackRock Inc history 4.04M $50.02M 0.00% Reduce
BlackRock Inc history 4.04M $50.02M 0.00% Reduce
Vanguard Group history 1.27M $15.71M 0.00% Reduce
Geode Capital Management history 1.01M $12.56M 0.00% Add
Morgan Stanley history 719.99K $8.91M 0.00% Hold
Morgan Stanley history 719.99K $8.91M 0.00% Hold
Goldman Sachs Group history 510.46K $6.32M 0.00% Reduce
Goldman Sachs Group history 510.46K $6.32M 0.00% Reduce
Northern Trust Corp history 373.70K $4.62M 0.00% Reduce
JPMorgan Chase & Co history 371.96K $4.60M 0.00% Reduce
JPMorgan Chase & Co history 371.96K $4.60M 0.00% Reduce
Charles Schwab Investment Management history 319.61K $3.96M 0.00% Reduce
UBS Group AG history 244.48K $3.03M 0.00% Reduce
Renaissance Technologies history 239.90K $2.97M 0.01% Add
Renaissance Technologies history 239.90K $2.97M 0.01% Add
BNY Mellon history 146.01K $1.81M 0.00% Reduce
Citadel Advisors history 142.50K $1.76M 0.00% Reduce
Citadel Advisors history 142.50K $1.76M 0.00% Reduce
Bank of America Corp history 131.99K $1.63M 0.00% Add
Deutsche Bank AG history 95.81K $1.19M 0.00% Hold
Deutsche Bank AG history 95.81K $1.19M 0.00% Hold
Citigroup Inc history 65.83K $814.60K 0.00% Reduce
Manulife Financial history 65.23K $807.23K 0.00% Reduce
Millennium Management history 52.47K $649.28K 0.00% Reduce
Wells Fargo & Co history 45.89K $567.88K 0.00% Reduce
MFS Investment Management history 43.82K $542.22K 0.00% Reduce
Legal & General Investment Management America history 41.35K $511.75K 0.00% Hold
Invesco Ltd history 37.64K $465.77K 0.00% Reduce
Franklin Resources history 19.75K $244.37K 0.00% Hold
Janus Henderson Group history 18.05K $237.23K 0.00% Hold
D. E. Shaw & Co history 17.80K $220.31K 0.00% New
Two Sigma Investments history 16.03K $198.41K 0.00% Reduce
Two Sigma Investments history 16.03K $198.41K 0.00% Reduce
T. Rowe Price Associates history 3.46M $42.77K 0.01% Reduce
Amundi US history 2.01K $22.80K 0.00% Add
PNC Financial Services history 488 $6.04K 0.00% Add

View all 40 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021
Fidelity Management & Research (FMR) 7.20M 7.55M 7.55M 7.90M 7.90M 7.94M 8.07M 8.07M 8.07M 8.01M 8.05M 8.03M 7.91M 6.76M 3.95M 3.16M 2.93M 2.68M 2.64M 2.65M
BlackRock Inc 4.87M 4.64M 4.11M 3.60M 3.94M 4.04M 4.12M 4.03M — — — — — — — — — — — —
D. E. Shaw & Co 1.61M 1.76M 1.68M 1.32M 391.50K 17.80K — — 11.10K — — — — 5.71K 26.86K 105.23K 74.60K 100.55K 125.47K 65.32K
Two Sigma Investments 1.26M 1.21M 670.14K 426.61K 201.45K 16.03K 38.39K 10.51K 71.56K — — 136.20K 162.73K 365.54K 203.44K 135.69K 230.43K 261.29K 301.45K 321.17K
Geode Capital Management 1.13M 1.10M 1.06M 1.02M 933.45K 1.01M 964.31K 963.48K 994.28K 924.58K 905.12K 859.06K 838.42K 779.82K 715.60K 635.72K 631.68K 651.98K 623.57K 620.17K
Morgan Stanley 995.35K 1.23M 1.25M 799.67K 953.26K 719.99K 719.49K 719.29K 810.70K 652.47K 482.26K 268.86K 152.59K 284.91K 180.40K 166.50K 352.58K 349.52K 179.53K 62.18K
Goldman Sachs Group 979.73K 818.88K 935.33K 353.22K 528.32K 510.46K 556.53K 415.29K 350.13K 308.89K 333.79K 250.32K 192.63K 225.08K 216.06K 266.54K 270.18K 258.56K 214.12K 75.91K
Renaissance Technologies 697.62K 607.51K 435.51K 371.30K 90.20K 239.90K 201.90K 182.80K 329.50K 389.70K 335.80K 260.60K 323.80K 407.30K 474.90K 636.90K 686.00K 394.20K 266.80K 257.20K
Northern Trust Corp 457.12K 369.54K 363.24K 334.66K 334.55K 373.70K 404.50K 372.65K 364.11K 397.26K 404.11K 409.85K 411.98K 382.69K 361.58K 347.15K 352.22K 364.79K 444.82K 440.99K
Charles Schwab Investment Management 355.90K 356.67K 357.33K 350.82K 275.08K 319.61K 327.15K 324.96K 327.14K 318.90K 313.23K 308.54K 312.48K 298.97K 300.85K 285.74K 277.48K 284.40K 255.61K 241.72K
AQR Capital Management 302.57K 204.02K 186.78K 214.54K — — — — — — 13.78K 18.51K 19.29K 7.29K — — — 8.36K 9.92K 13.35K
UBS Group AG 241.43K 328.49K 426.36K 400.85K 60.66K 244.48K 371.29K 62.51K 44.77K 198.68K 132.50K 45.25K 22.38K 61.64K 91.07K 6.15K 20.82K 88.42K 74.37K 77.52K
Bank of America Corp 208.25K 393.63K 427.36K 277.10K 210.94K 131.99K 119.01K 82.06K 118.86K 240.34K 287.36K 109.42K 197.86K 564.44K 121.67K 83.10K 65.34K 158.22K 168.50K 33.57K
Marshall Wace 190.83K 44.57K 54.78K — — — — — — — — — 10.87K — — 107.80K 178.39K 10.53K 214.69K 68.89K
Millennium Management 149.90K 50.30K 99.38K 621.10K 170.58K 52.47K 123.00K 112.54K 31.29K 322.24K 37.66K 265.52K 43.30K 194.64K 213.61K 173.44K 204.67K 272.68K 229.89K 151.67K
BNY Mellon 133.91K 136.32K 132.70K 153.80K 148.35K 146.01K 150.24K 130.79K 165.42K 145.84K 442.31K 499.38K 514.23K 164.09K 137.00K 140.19K 119.36K 154.28K 152.46K 137.29K
MFS Investment Management 126.99K 132.05K 45.97K 47.49K 44.36K 43.82K 44.81K — — — — — — — — — — — 41.86K 42.71K
Citadel Advisors 116.90K 572.77K 1.08M 971.71K 1.37M 142.50K 182.22K 290.38K 396.75K 281.73K 296.69K 190.74K 62.34K 62.70K 40.55K 350.14K 200.81K 100.22K 60.99K 146.31K
Invesco Ltd 71.48K 49.81K 26.61K 31.30K 36.88K 37.64K 42.85K 41.21K 41.10K 40.50K 26.61K 30.72K 63.95K 28.35K 42.30K 17.48K 243.35K 191.22K 157.82K 347.42K
Citigroup Inc 57.83K 8.15K 12.32K 3.59K 49.30K 65.83K 68.43K 32.07K 24.66K 259.87K 87.58K 67.93K 97.55K 114.80K 63.40K 98.14K 85.38K 25.59K 100.29K 53.28K

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