PRLD — PRELUDE THERAPEUTICS INC
Reported value held$43.41M
Funds holding (latest)32
SectorHealth Care
Funds holding (Q2 2026)23
Institutional value$34.29M · 6.46M sh
New / Add / Cut / Exit8 / 9 / 5 / 2
Top-5 / Top-10 concentration77.4% / 95.4%
Institutional holdings change
Accumulating +86.6%
(+3.00M sh)
Institutional value change
Up +189.7%
As of Q2 2026, 23 SEC-registered investment managers reported holding PRLD (PRELUDE THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $34.29M across 6.46M shares. That is +86.6% by share count (+3.00M shares) versus the previous quarter, while reported value moved +189.7%. Ownership is concentrated: the five largest holders account for 77.4% of reported value and the top ten for 95.4%.
Compared with the prior quarter, 8 opened new positions, 9 added to existing stakes, 5 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
PRLD is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 23 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 1.80M | $9.58M | 0.00% | Add |
| Two Sigma Investments history | 993.37K | $5.29M | 0.00% | Add |
| Millennium Management history | 844.99K | $4.50M | 0.00% | Add |
| Geode Capital Management history | 841.86K | $4.49M | 0.00% | Add |
| Morgan Stanley history | 503.86K | $2.69M | 0.00% | Add |
| UBS Group AG history | 318.80K | $1.70M | 0.00% | Add |
| Renaissance Technologies history | 281.20K | $1.50M | 0.00% | Add |
| Northern Trust Corp history | 240.60K | $1.28M | 0.00% | Add |
| Marshall Wace history | 190.69K | $1.02M | 0.00% | Reduce |
| Goldman Sachs Group history | 120.83K | $644.04K | 0.00% | Reduce |
| BNY Mellon history | 68.19K | $363.44K | 0.00% | New |
| Charles Schwab Investment Management history | 67.62K | $360.43K | 0.00% | New |
| Invesco Ltd history | 34.74K | $185.18K | 0.00% | New |
| Deutsche Bank AG history | 27.82K | $148.30K | 0.00% | New |
| Wells Fargo & Co history | 25.32K | $134.98K | 0.00% | New |
| Bank of America Corp history | 23.88K | $127.25K | 0.00% | Reduce |
| Citadel Advisors history | 16.10K | $85.81K | 0.00% | Reduce |
| Citigroup Inc history | 13.03K | $69.47K | 0.00% | Add |
| JPMorgan Chase & Co history | 13.54K | $66.74K | 0.00% | New |
| Fidelity Management & Research (FMR) history | 5.63K | $30.00K | 0.00% | Reduce |
| Legal & General Investment Management America history | 2.70K | $14.39K | 0.00% | New |
| PNC Financial Services history | 1.17K | $6.24K | 0.00% | Hold |
| T. Rowe Price Associates history | 22.76K | $122 | 0.00% | New |
Q1 2026 — 17 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Two Sigma Investments history | 923.63K | $3.16M | 0.00% | Add |
| Millennium Management history | 382.74K | $1.31M | 0.00% | Add |
| Marshall Wace history | 358.91K | $1.23M | 0.00% | Add |
| Morgan Stanley history | 322.16K | $1.10M | 0.00% | Reduce |
| BlackRock Inc history | 321.89K | $1.10M | 0.00% | Add |
| Geode Capital Management history | 302.46K | $1.03M | 0.00% | Add |
| Renaissance Technologies history | 275.20K | $941.18K | 0.00% | Add |
| Goldman Sachs Group history | 236.47K | $808.72K | 0.00% | Add |
| Citadel Advisors history | 124.38K | $425.37K | 0.00% | New |
| UBS Group AG history | 64.50K | $220.61K | 0.00% | Add |
| Bank of America Corp history | 56.52K | $193.32K | 0.00% | Add |
| Northern Trust Corp history | 50.12K | $171.41K | 0.00% | Hold |
| Prudential Financial history | 17.42K | $59.58K | 0.00% | Add |
| Point72 Asset Management history | 16.33K | $55.84K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 6.01K | $20.55K | 0.00% | Reduce |
| PNC Financial Services history | 1.17K | $4.00K | 0.00% | Hold |
| Citigroup Inc history | 5 | $17 | 0.00% | Add |
Q4 2025 — 20 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 1.41M | $4.10M | 0.00% | Add |
| Two Sigma Investments history | 788.70K | $2.29M | 0.00% | Add |
| Morgan Stanley history | 334.92K | $971.26K | 0.00% | Add |
| Marshall Wace history | 273.88K | $794.26K | 0.00% | New |
| Geode Capital Management history | 272.89K | $791.50K | 0.00% | Add |
| Renaissance Technologies history | 271.30K | $786.77K | 0.00% | Reduce |
| BlackRock Inc history | 266.28K | $772.21K | 0.00% | Hold |
| Millennium Management history | 151.00K | $437.89K | 0.00% | Reduce |
| Goldman Sachs Group history | 117.48K | $340.68K | 0.00% | Add |
| Manulife Financial history | 70.55K | $200.43K | 0.00% | Add |
| Point72 Asset Management history | 59.17K | $171.59K | 0.00% | New |
| Northern Trust Corp history | 50.12K | $145.35K | 0.00% | Add |
| Prudential Financial history | 15.52K | $45.01K | 0.00% | Reduce |
| Bank of America Corp history | 9.81K | $28.44K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 6.15K | $17.84K | 0.00% | Reduce |
| UBS Group AG history | 1.86K | $5.38K | 0.00% | Reduce |
| PNC Financial Services history | 1.17K | $3.40K | 0.00% | Hold |
| T. Rowe Price Associates history | 755.96K | $2.19K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 62 | $180 | 0.00% | Reduce |
| Citigroup Inc history | 1 | $3 | 0.00% | Reduce |
Q3 2025 — 19 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Millennium Management history | 1.15M | $1.65M | 0.00% | Add |
| Vanguard Group history | 992.85K | $1.43M | 0.00% | Add |
| Renaissance Technologies history | 544.00K | $783.36K | 0.00% | Reduce |
| Morgan Stanley history | 284.20K | $409.25K | 0.00% | Hold |
| BlackRock Inc history | 264.97K | $381.56K | 0.00% | Reduce |
| Geode Capital Management history | 217.57K | $313.37K | 0.00% | Hold |
| Two Sigma Investments history | 152.23K | $219.22K | 0.00% | Reduce |
| Goldman Sachs Group history | 79.33K | $114.23K | 0.00% | Reduce |
| Manulife Financial history | 69.25K | $99.72K | 0.00% | Hold |
| Northern Trust Corp history | 36.42K | $52.45K | 0.00% | Reduce |
| Prudential Financial history | 25.84K | $37.21K | 0.00% | New |
| AQR Capital Management history | 10.50K | $15.12K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 9.10K | $13.10K | 0.00% | Reduce |
| Bank of America Corp history | 8.85K | $12.74K | 0.00% | Reduce |
| Citigroup Inc history | 5.97K | $8.60K | 0.00% | Add |
| UBS Group AG history | 4.17K | $6.01K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 3.88K | $5.58K | 0.00% | Add |
| PNC Financial Services history | 1.17K | $1.69K | 0.00% | Reduce |
| T. Rowe Price Associates history | 876.34K | $1.26K | 0.00% | Reduce |
Q2 2025 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 932.57K | $754.45K | 0.00% | Reduce |
| Renaissance Technologies history | 581.80K | $470.91K | 0.00% | Reduce |
| Renaissance Technologies history | 581.80K | $470.91K | 0.00% | Reduce |
| BlackRock Inc history | 432.56K | $350.11K | 0.00% | Reduce |
| BlackRock Inc history | 432.56K | $350.11K | 0.00% | Reduce |
| Morgan Stanley history | 284.38K | $230.18K | 0.00% | Reduce |
| Morgan Stanley history | 284.38K | $230.18K | 0.00% | Reduce |
| Millennium Management history | 248.42K | $201.07K | 0.00% | Add |
| Geode Capital Management history | 217.57K | $176.13K | 0.00% | Reduce |
| Two Sigma Investments history | 154.98K | $125.44K | 0.00% | Reduce |
| Two Sigma Investments history | 154.98K | $125.44K | 0.00% | Reduce |
| Goldman Sachs Group history | 149.18K | $120.75K | 0.00% | Reduce |
| Goldman Sachs Group history | 149.18K | $120.75K | 0.00% | Reduce |
| UBS Group AG history | 104.20K | $84.30K | 0.00% | Add |
| Charles Schwab Investment Management history | 80.84K | $65.44K | 0.00% | Reduce |
| Manulife Financial history | 69.25K | $56.05K | 0.00% | Hold |
| AQR Capital Management history | 43.65K | $35.33K | 0.00% | Add |
| Marshall Wace history | 41.75K | $33.81K | 0.00% | New |
| Northern Trust Corp history | 38.13K | $30.86K | 0.00% | Reduce |
| Citadel Advisors history | 33.62K | $27.22K | 0.00% | Add |
| Citadel Advisors history | 33.62K | $27.22K | 0.00% | Add |
| Bank of America Corp history | 11.29K | $9.14K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 11.17K | $9.04K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 11.17K | $9.04K | 0.00% | Reduce |
| Citigroup Inc history | 4.72K | $3.82K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 1.95K | $1.58K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 1.95K | $1.58K | 0.00% | Reduce |
| PNC Financial Services history | 1.18K | $956 | 0.00% | Reduce |
| T. Rowe Price Associates history | 927.61K | $743 | 0.00% | Reduce |
| Wells Fargo & Co history | 297 | $240 | 0.00% | Reduce |
Q1 2025 — 33 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 1.05M | $804.65K | 0.00% | Reduce |
| BlackRock Inc history | 1.05M | $804.65K | 0.00% | Reduce |
| Vanguard Group history | 1.01M | $775.07K | 0.00% | Hold |
| Renaissance Technologies history | 656.70K | $504.35K | 0.00% | Add |
| Renaissance Technologies history | 656.70K | $504.35K | 0.00% | Add |
| Geode Capital Management history | 404.95K | $311.05K | 0.00% | Add |
| Morgan Stanley history | 302.78K | $232.53K | 0.00% | Reduce |
| Morgan Stanley history | 302.78K | $232.53K | 0.00% | Reduce |
| Two Sigma Investments history | 183.67K | $141.06K | 0.00% | Reduce |
| Two Sigma Investments history | 183.67K | $141.06K | 0.00% | Reduce |
| Goldman Sachs Group history | 155.22K | $119.20K | 0.00% | Add |
| Goldman Sachs Group history | 155.22K | $119.20K | 0.00% | Add |
| Millennium Management history | 146.77K | $112.72K | 0.00% | Reduce |
| Northern Trust Corp history | 116.91K | $89.78K | 0.00% | Add |
| Charles Schwab Investment Management history | 114.05K | $87.59K | 0.00% | Reduce |
| UBS Group AG history | 96.16K | $73.85K | 0.00% | Add |
| Deutsche Bank AG history | 80.72K | $62.16K | 0.00% | Reduce |
| Deutsche Bank AG history | 80.72K | $62.16K | 0.00% | Reduce |
| Manulife Financial history | 69.25K | $53.19K | 0.00% | Reduce |
| AQR Capital Management history | 33.82K | $25.98K | 0.00% | Add |
| BNY Mellon history | 28.61K | $21.98K | 0.00% | Hold |
| Citadel Advisors history | 23.93K | $18.38K | 0.00% | Add |
| Citadel Advisors history | 23.93K | $18.38K | 0.00% | Add |
| JPMorgan Chase & Co history | 23.78K | $18.26K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 23.78K | $18.26K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 20.24K | $15.54K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 20.24K | $15.54K | 0.00% | Add |
| Bank of America Corp history | 15.45K | $11.86K | 0.00% | Reduce |
| Citigroup Inc history | 9.30K | $7.14K | 0.00% | Reduce |
| Wells Fargo & Co history | 7.91K | $6.08K | 0.00% | Add |
| PNC Financial Services history | 1.19K | $915 | 0.00% | Add |
| T. Rowe Price Associates history | 976.15K | $750 | 0.00% | Reduce |
| Legal & General Investment Management America history | 962 | $739 | 0.00% | Hold |
New Positions (Q2 2026)
- BNY Mellon 68.19K sh · $363.44K
- Charles Schwab Investment Management 67.62K sh · $360.43K
- Invesco Ltd 34.74K sh · $185.18K
- Deutsche Bank AG 27.82K sh · $148.30K
- Wells Fargo & Co 25.32K sh · $134.98K
- JPMorgan Chase & Co 13.54K sh · $66.74K
- Legal & General Investment Management America 2.70K sh · $14.39K
- T. Rowe Price Associates 22.76K sh · $122
Fully Exited (vs previous quarter)
- Prudential Financial sold 17.42K sh · $59.58K
- Point72 Asset Management sold 16.33K sh · $55.84K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | 1.80M | 321.89K | 266.28K | 264.97K | 432.56K | 1.05M | 1.07M | 1.06M | — | — | — | — | — | — | — | — | — | — | — | — |
| Two Sigma Investments | 993.37K | 923.63K | 788.70K | 152.23K | 154.98K | 183.67K | 231.84K | 56.93K | 43.13K | 60.60K | 58.28K | 12.81K | 39.29K | 22.45K | 51.90K | 105.60K | 223.84K | 180.41K | 282.77K | — |
| Millennium Management | 844.99K | 382.74K | 151.00K | 1.15M | 248.42K | 146.77K | 462.56K | 160.52K | — | 101.85K | 96.97K | 63.87K | 138.49K | 136.52K | 49.74K | 60.43K | 90.94K | 39.31K | 444.11K | 40.85K |
| Geode Capital Management | 841.86K | 302.46K | 272.89K | 217.57K | 217.57K | 404.95K | 402.34K | 391.72K | 361.95K | 361.63K | 349.37K | 331.10K | 242.29K | 145.90K | 144.68K | 153.09K | 135.64K | 207.58K | 212.64K | 249.17K |
| Morgan Stanley | 503.86K | 322.16K | 334.92K | 284.20K | 284.38K | 302.78K | 365.16K | 323.69K | 287.35K | 296.20K | 298.80K | 244.47K | 195.33K | 141.66K | 89.95K | 177.79K | 480.79K | 546.48K | 845.71K | 756.79K |
| UBS Group AG | 318.80K | 64.50K | 1.86K | 4.17K | 104.20K | 96.16K | 67.39K | 7.02K | 10.93K | 15.65K | 19.87K | 7.41K | 6.89K | 980 | 1.04K | 68 | 2.71K | 183 | 1.94K | 37.00K |
| Renaissance Technologies | 281.20K | 275.20K | 271.30K | 544.00K | 581.80K | 656.70K | 634.50K | 196.90K | 206.60K | 244.80K | 216.40K | 139.37K | 183.30K | 138.50K | 136.50K | 143.40K | 160.49K | 40.10K | 127.20K | — |
| Northern Trust Corp | 240.60K | 50.12K | 50.12K | 36.42K | 38.13K | 116.91K | 83.39K | 106.38K | 124.69K | 122.15K | 114.10K | 115.52K | 81.59K | 21.17K | 21.17K | 21.17K | 21.17K | 101.91K | 107.18K | 106.42K |
| Marshall Wace | 190.69K | 358.91K | 273.88K | — | 41.75K | — | 392.15K | 359.14K | — | — | — | — | — | — | — | — | 45.72K | 111.78K | 268.02K | — |
| Goldman Sachs Group | 120.83K | 236.47K | 117.48K | 79.33K | 149.18K | 155.22K | 148.33K | 95.16K | 74.92K | 67.43K | 69.47K | 67.69K | 23.79K | 49.50K | 15.76K | 21.73K | 44.30K | 24.09K | 113.33K | 8.66K |
| BNY Mellon | 68.19K | — | — | — | — | 28.61K | 28.61K | 28.61K | 36.28K | 40.07K | 50.60K | 32.88K | 30.82K | — | 28.88K | 29.18K | 29.19K | 59.82K | 57.68K | 34.31K |
| Charles Schwab Investment Management | 67.62K | — | — | — | 80.84K | 114.05K | 117.20K | 133.25K | 128.03K | 127.37K | 124.70K | 123.03K | 85.79K | 62.85K | 63.72K | 54.05K | 63.20K | 75.93K | 85.14K | 83.98K |
| Invesco Ltd | 34.74K | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Deutsche Bank AG | 27.82K | — | — | — | — | 80.72K | 123.90K | 14.62K | 14.62K | — | — | 446 | — | — | — | — | — | 6.19K | 6.89K | 6.54K |
| Wells Fargo & Co | 25.32K | — | — | — | 297 | 7.91K | 7.74K | 6.05K | 5.79K | 5.27K | 4.60K | 3.64K | 4.22K | 178 | 342 | 371 | 187 | 100 | 3.15K | 43 |
| Bank of America Corp | 23.88K | 56.52K | 9.81K | 8.85K | 11.29K | 15.45K | 20.65K | 24.94K | 34.28K | 32.26K | 37.49K | 52.65K | 11.49K | 28.19K | 157.82K | 167.48K | 133.50K | 135.24K | 78.48K | 7.09K |
| Citadel Advisors | 16.10K | 124.38K | — | — | 33.62K | 23.93K | 16.70K | 16.02K | 31.89K | 30.00K | 97.03K | 301.50K | 38.57K | — | 18.33K | 160.93K | 406.82K | 222.30K | 138.50K | 14.49K |
| Citigroup Inc | 13.03K | 5 | 1 | 5.97K | 4.72K | 9.30K | 10.21K | 9.65K | 3.01K | 2.81K | 2.13K | 526 | 3.84K | 70.77K | 60.07K | 8.53K | 841 | 1.72K | 4.08K | 24.27K |
| JPMorgan Chase & Co | 13.54K | — | 62 | 3.88K | 1.95K | 23.78K | 61.15K | 5.97K | 5.86K | 6.25K | 9.38K | 17.35K | 9.34K | 1.39K | 1.30K | 2.45K | 2.03K | 9.26K | 7.22K | 7.02K |
| Fidelity Management & Research (FMR) | 5.63K | 6.01K | 6.15K | 9.10K | 11.17K | 20.24K | 8.50K | 7.62K | 9.57K | 11.55K | 264.69K | 5.13M | 5.94M | 4.55M | 4.59M | 4.64M | 4.30M | 5.37M | 5.94M | 7.06M |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details