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PBYI — PUMA BIOTECHNOLOGY INC

Reported value held$138.14M
Funds holding (latest)40
SectorHealth Care
Funds holding (Q2 2026)29
Institutional value$109.26M · 13.51M sh
New / Add / Cut / Exit2 / 16 / 9 / 2
Top-5 / Top-10 concentration62.2% / 82.8%
Institutional holdings change Accumulating +1.0% (+132.11K sh)
Institutional value change Up +28.1%

As of Q2 2026, 29 SEC-registered investment managers reported holding PBYI (PUMA BIOTECHNOLOGY INC) in their latest 13F filings, with a combined reported value of $109.26M across 13.51M shares. That is +1.0% by share count (+132.11K shares) versus the previous quarter, while reported value moved +28.1%. Ownership is concentrated: the five largest holders account for 62.2% of reported value and the top ten for 82.8%.

Compared with the prior quarter, 2 opened new positions, 16 added to existing stakes, 9 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

PBYI is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 29 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.80M $30.86M 0.00% Add
Renaissance Technologies history 1.84M $14.89M 0.02% Reduce
Geode Capital Management history 1.34M $10.86M 0.00% Add
AQR Capital Management history 725.19K $5.88M 0.00% Reduce
Goldman Sachs Group history 669.16K $5.43M 0.00% Hold
Northern Trust Corp history 652.39K $5.29M 0.00% Add
UBS Group AG history 636.76K $5.16M 0.00% Add
Millennium Management history 602.24K $4.88M 0.00% Reduce
Arrowstreet Capital history 532.45K $4.32M 0.00% Reduce
BNY Mellon history 360.73K $2.93M 0.00% Add
D. E. Shaw & Co history 316.34K $2.57M 0.00% Reduce
Invesco Ltd history 301.00K $2.44M 0.00% Add
Morgan Stanley history 265.67K $2.15M 0.00% Reduce
Prudential Financial history 213.60K $1.73M 0.00% Reduce
JPMorgan Chase & Co history 211.34K $1.73M 0.00% New
Fidelity Management & Research (FMR) history 211.44K $1.71M 0.00% Add
Franklin Resources history 172.01K $1.40M 0.00% Reduce
Two Sigma Investments history 140.59K $1.14M 0.00% Add
Charles Schwab Investment Management history 128.24K $1.04M 0.00% Add
Wellington Management Group history 126.09K $1.02M 0.00% New
CPP Investments history 73.50K $596.09K 0.00% Add
Deutsche Bank AG history 43.19K $350.29K 0.00% Add
Wells Fargo & Co history 37.61K $304.98K 0.00% Add
Bank of America Corp history 31.75K $257.47K 0.00% Reduce
Citigroup Inc history 21.67K $175.71K 0.00% Add
Manulife Financial history 12.06K $97.77K 0.00% Add
Legal & General Investment Management America history 4.32K $35.01K 0.00% Add
PNC Financial Services history 513 $4.16K 0.00% Hold
T. Rowe Price Associates history 36.34K $295 0.00% Add

Q1 2026 — 29 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.60M $23.00M 0.00% Reduce
Renaissance Technologies history 1.94M $12.41M 0.02% Reduce
Millennium Management history 1.48M $9.44M 0.00% Add
Geode Capital Management history 1.02M $6.50M 0.00% Add
AQR Capital Management history 800.19K $5.11M 0.00% Add
Goldman Sachs Group history 669.72K $4.28M 0.00% Reduce
Northern Trust Corp history 641.75K $4.10M 0.00% Add
Arrowstreet Capital history 538.15K $3.44M 0.00% Reduce
UBS Group AG history 534.23K $3.41M 0.00% Add
Morgan Stanley history 359.74K $2.30M 0.00% Add
D. E. Shaw & Co history 351.24K $2.24M 0.00% Reduce
BNY Mellon history 347.88K $2.22M 0.00% Reduce
Prudential Financial history 253.04K $1.62M 0.00% Reduce
Franklin Resources history 215.39K $1.38M 0.00% Add
Fidelity Management & Research (FMR) history 191.83K $1.23M 0.00% Add
Charles Schwab Investment Management history 115.92K $740.70K 0.00% Reduce
Invesco Ltd history 95.04K $607.33K 0.00% Reduce
Bank of America Corp history 40.36K $257.93K 0.00% Reduce
Deutsche Bank AG history 33.15K $211.80K 0.00% New
Citadel Advisors history 29.96K $191.44K 0.00% Reduce
CPP Investments history 22.80K $145.69K 0.00% Reduce
Lazard Asset Management history 17.97K $114.83K 0.00% Reduce
Wells Fargo & Co history 16.27K $103.98K 0.00% Reduce
Two Sigma Investments history 13.00K $83.07K 0.00% Reduce
Manulife Financial history 11.77K $75.18K 0.00% Reduce
Legal & General Investment Management America history 3.56K $22.77K 0.00% Hold
Citigroup Inc history 3.42K $21.87K 0.00% Add
PNC Financial Services history 513 $3.28K 0.00% Hold
T. Rowe Price Associates history 31.31K $201 0.00% Add

Q4 2025 — 32 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 3.80M $22.60M 0.00% Add
BlackRock Inc history 3.64M $21.67M 0.00% Add
Renaissance Technologies history 2.12M $12.64M 0.02% Reduce
Geode Capital Management history 994.35K $5.92M 0.00% Add
Goldman Sachs Group history 793.96K $4.72M 0.00% Add
AQR Capital Management history 666.61K $3.97M 0.00% Add
Northern Trust Corp history 616.20K $3.67M 0.00% Add
Arrowstreet Capital history 547.85K $3.26M 0.00% Add
D. E. Shaw & Co history 378.30K $2.25M 0.00% Reduce
BNY Mellon history 351.88K $2.09M 0.00% Reduce
Morgan Stanley history 326.77K $1.94M 0.00% Reduce
Prudential Financial history 286.51K $1.70M 0.00% Add
Franklin Resources history 182.71K $1.09M 0.00% Add
Citadel Advisors history 177.47K $1.06M 0.00% Add
Fidelity Management & Research (FMR) history 163.87K $975.03K 0.00% Add
Two Sigma Investments history 162.35K $965.99K 0.00% Add
UBS Group AG history 127.31K $757.51K 0.00% Reduce
Charles Schwab Investment Management history 125.37K $745.96K 0.00% Hold
Invesco Ltd history 108.30K $644.39K 0.00% Add
CPP Investments history 75.20K $447.44K 0.00% New
Lazard Asset Management history 59.58K $354.47K 0.00% Reduce
Bank of America Corp history 52.38K $311.69K 0.00% Add
Wells Fargo & Co history 48.28K $287.27K 0.00% Add
JPMorgan Chase & Co history 21.11K $125.59K 0.00% Add
Millennium Management history 16.61K $98.85K 0.00% Reduce
Manulife Financial history 13.43K $79.89K 0.00% Reduce
Causeway Capital Management history 13.31K $79.19K 0.00% Reduce
Royce & Associates history 11.91K $70.89K 0.00% Reduce
Legal & General Investment Management America history 3.56K $21.21K 0.00% Hold
Citigroup Inc history 2.38K $14.16K 0.00% Add
PNC Financial Services history 513 $3.05K 0.00% Add
T. Rowe Price Associates history 25.94K $155 0.00% Add

Q3 2025 — 34 funds

FundSharesValuePortfolio WeightChange
Vanguard Group history 3.69M $19.60M 0.00% Hold
BlackRock Inc history 3.58M $19.00M 0.00% Reduce
Renaissance Technologies history 2.15M $11.42M 0.01% Add
Geode Capital Management history 983.52K $5.22M 0.00% Add
Marshall Wace history 557.55K $2.96M 0.00% Add
Northern Trust Corp history 526.74K $2.80M 0.00% Add
D. E. Shaw & Co history 498.60K $2.65M 0.00% Reduce
Arrowstreet Capital history 464.73K $2.47M 0.00% Add
Morgan Stanley history 378.08K $2.01M 0.00% Add
UBS Group AG history 376.09K $2.00M 0.00% Add
BNY Mellon history 355.37K $1.89M 0.00% Add
Goldman Sachs Group history 234.62K $1.25M 0.00% Add
Prudential Financial history 220.94K $1.17M 0.00% Reduce
Franklin Resources history 173.70K $922.34K 0.00% Add
Wellington Management Group history 149.55K $794.12K 0.00% New
Fidelity Management & Research (FMR) history 145.28K $771.46K 0.00% Add
AQR Capital Management history 130.67K $693.87K 0.00% Reduce
Charles Schwab Investment Management history 125.37K $665.73K 0.00% Reduce
Millennium Management history 105.63K $560.91K 0.00% Reduce
Invesco Ltd history 63.82K $338.87K 0.00% Add
Lazard Asset Management history 63.15K $335.31K 0.00% New
Two Sigma Investments history 56.13K $298.03K 0.00% Reduce
Bank of America Corp history 44.97K $238.78K 0.00% Reduce
Wells Fargo & Co history 32.53K $172.74K 0.00% Add
Deutsche Bank AG history 30.74K $163.25K 0.00% Hold
Citadel Advisors history 23.30K $123.72K 0.00% Reduce
Royce & Associates history 18.73K $99.43K 0.00% Add
JPMorgan Chase & Co history 17.29K $91.78K 0.00% Reduce
Manulife Financial history 15.16K $80.48K 0.00% Reduce
Causeway Capital Management history 14.10K $74.84K 0.00% Hold
Legal & General Investment Management America history 3.56K $18.93K 0.00% Hold
Citigroup Inc history 859 $4.56K 0.00% Reduce
PNC Financial Services history 117 $621 0.00% New
T. Rowe Price Associates history 21.62K $115 0.00% Add

Q2 2025 — 41 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.84M $13.16M 0.00% Hold
BlackRock Inc history 3.84M $13.16M 0.00% Hold
Vanguard Group history 3.71M $12.71M 0.00% Add
Renaissance Technologies history 1.87M $6.43M 0.01% Add
Renaissance Technologies history 1.87M $6.43M 0.01% Add
Geode Capital Management history 971.67K $3.33M 0.00% Add
Janus Henderson Group history 745.54K $2.56M 0.00% New
D. E. Shaw & Co history 640.78K $2.20M 0.00% Add
Citadel Advisors history 554.52K $1.90M 0.00% Add
Citadel Advisors history 554.52K $1.90M 0.00% Add
Arrowstreet Capital history 451.63K $1.55M 0.00% Add
BNY Mellon history 344.08K $1.18M 0.00% Add
Millennium Management history 334.61K $1.15M 0.00% Reduce
Morgan Stanley history 322.46K $1.11M 0.00% Add
Morgan Stanley history 322.46K $1.11M 0.00% Add
Northern Trust Corp history 302.01K $1.04M 0.00% Reduce
Prudential Financial history 281.24K $964.67K 0.00% Reduce
UBS Group AG history 274.10K $940.16K 0.00% Reduce
Goldman Sachs Group history 202.03K $692.96K 0.00% Reduce
Goldman Sachs Group history 202.03K $692.96K 0.00% Reduce
Two Sigma Investments history 190.62K $653.83K 0.00% Reduce
Two Sigma Investments history 190.62K $653.83K 0.00% Reduce
AQR Capital Management history 141.77K $486.28K 0.00% Add
Fidelity Management & Research (FMR) history 132.36K $454.01K 0.00% Add
Fidelity Management & Research (FMR) history 132.36K $454.01K 0.00% Add
Charles Schwab Investment Management history 127.44K $437.13K 0.00% Add
Marshall Wace history 73.42K $251.81K 0.00% Reduce
Bank of America Corp history 67.24K $230.64K 0.00% Reduce
Invesco Ltd history 49.98K $171.44K 0.00% Add
Deutsche Bank AG history 30.74K $105.45K 0.00% Hold
Deutsche Bank AG history 30.74K $105.45K 0.00% Hold
Wells Fargo & Co history 28.03K $96.13K 0.00% Add
JPMorgan Chase & Co history 20.25K $69.44K 0.00% Reduce
JPMorgan Chase & Co history 20.25K $69.44K 0.00% Reduce
Franklin Resources history 17.69K $60.68K 0.00% Reduce
Royce & Associates history 17.29K $59.29K 0.00% Reduce
Manulife Financial history 15.58K $53.43K 0.00% Reduce
Citigroup Inc history 14.32K $49.12K 0.00% Reduce
Causeway Capital Management history 14.10K $48.35K 0.00% Hold
Legal & General Investment Management America history 3.56K $12.22K 0.00% Reduce
T. Rowe Price Associates history 19.57K $68 0.00% Hold

Q1 2025 — 41 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.85M $11.39M 0.00% Add
BlackRock Inc history 3.85M $11.39M 0.00% Add
Vanguard Group history 3.67M $10.86M 0.00% Add
Renaissance Technologies history 1.83M $5.41M 0.01% Add
Renaissance Technologies history 1.83M $5.41M 0.01% Add
Millennium Management history 1.39M $4.10M 0.00% Reduce
Geode Capital Management history 955.46K $2.83M 0.00% Add
D. E. Shaw & Co history 571.66K $1.69M 0.00% Add
Arrowstreet Capital history 358.62K $1.06M 0.00% New
BNY Mellon history 340.89K $1.01M 0.00% Add
Northern Trust Corp history 317.44K $939.62K 0.00% Reduce
Prudential Financial history 308.15K $912.14K 0.00% Add
Goldman Sachs Group history 294.24K $870.96K 0.00% Reduce
Goldman Sachs Group history 294.24K $870.96K 0.00% Reduce
UBS Group AG history 279.67K $827.81K 0.00% Add
Morgan Stanley history 262.54K $777.11K 0.00% Reduce
Morgan Stanley history 262.54K $777.11K 0.00% Reduce
Marshall Wace history 216.41K $640.58K 0.00% Add
Two Sigma Investments history 192.80K $570.69K 0.00% Add
Two Sigma Investments history 192.80K $570.69K 0.00% Add
Fidelity Management & Research (FMR) history 127.17K $376.44K 0.00% Reduce
Fidelity Management & Research (FMR) history 127.17K $376.44K 0.00% Reduce
Charles Schwab Investment Management history 118.25K $350.03K 0.00% Hold
Bank of America Corp history 93.09K $275.54K 0.00% Add
Franklin Resources history 78.17K $231.40K 0.00% Add
AQR Capital Management history 50.46K $149.35K 0.00% Add
JPMorgan Chase & Co history 48.35K $143.12K 0.00% Reduce
JPMorgan Chase & Co history 48.35K $143.12K 0.00% Reduce
Invesco Ltd history 37.63K $111.39K 0.00% Add
Citadel Advisors history 32.90K $97.38K 0.00% Reduce
Citadel Advisors history 32.90K $97.38K 0.00% Reduce
Deutsche Bank AG history 30.74K $91.00K 0.00% New
Deutsche Bank AG history 30.74K $91.00K 0.00% New
Citigroup Inc history 29.47K $87.22K 0.00% Reduce
Wells Fargo & Co history 23.45K $69.41K 0.00% Add
Royce & Associates history 18.73K $55.43K 0.00% Hold
Manulife Financial history 16.51K $48.86K 0.00% New
Causeway Capital Management history 14.10K $41.72K 0.00% New
Legal & General Investment Management America history 3.91K $11.58K 0.00% Hold
T. Rowe Price Associates history 19.57K $58 0.00% Add
Lazard Asset Management history 2.10K $6 0.00% Reduce

View all 40 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021
BlackRock Inc 3.80M 3.60M 3.64M 3.58M 3.84M 3.85M 3.82M 3.83M — — — — — — — — — — — —
Renaissance Technologies 1.84M 1.94M 2.12M 2.15M 1.87M 1.83M 1.76M 1.77M 1.75M 1.73M 1.67M 1.73M 1.76M 1.83M 1.70M 1.80M 1.98M 1.77M 1.82M 1.63M
Geode Capital Management 1.34M 1.02M 994.35K 983.52K 971.67K 955.46K 919.43K 917.37K 950.15K 452.97K 444.05K 425.51K 396.40K 391.62K 380.91K 374.67K 370.09K 599.41K 637.29K 607.15K
AQR Capital Management 725.19K 800.19K 666.61K 130.67K 141.77K 50.46K 10.82K — — — — — — — — — — — — —
Goldman Sachs Group 669.16K 669.72K 793.96K 234.62K 202.03K 294.24K 314.10K 305.72K 200.58K 450.58K 115.95K 84.14K 73.91K 74.00K 76.45K 119.53K 220.89K 439.83K 2.28M 807.93K
Northern Trust Corp 652.39K 641.75K 616.20K 526.74K 302.01K 317.44K 325.42K 317.74K 105.06K 83.54K 83.76K 69.45K 69.59K 69.84K 66.44K 68.95K 68.99K 284.13K 305.16K 349.80K
UBS Group AG 636.76K 534.23K 127.31K 376.09K 274.10K 279.67K 155.57K 27.09K 20.33K 10.64K 11.12K 3.41K 4.06K 10.93K 3.44K 3.42K 4.54K 25.98K 17.46K 6.52K
Millennium Management 602.24K 1.48M 16.61K 105.63K 334.61K 1.39M 1.89M 2.88M 3.16M 3.29M 3.16M 3.28M 3.07M 3.23M 2.68M 3.01M 2.22M 1.91M 1.91M 1.67M
Arrowstreet Capital 532.45K 538.15K 547.85K 464.73K 451.63K 358.62K — — 92.17K 230.43K — — — — — — — — — —
BNY Mellon 360.73K 347.88K 351.88K 355.37K 344.08K 340.89K 331.85K 277.70K 309.00K 188.89K 46.43K 52.92K 72.27K 73.36K 58.00K 30.03K 32.05K 115.40K 116.10K 119.68K
D. E. Shaw & Co 316.34K 351.24K 378.30K 498.60K 640.78K 571.66K 222.61K 57.39K — — — — — — 132.18K 538.54K 960.07K 1.01M 735.96K 50.27K
Invesco Ltd 301.00K 95.04K 108.30K 63.82K 49.98K 37.63K 19.92K 18.74K 118.83K — — — — — — — — 11.86K 11.82K 15.37K
Morgan Stanley 265.67K 359.74K 326.77K 378.08K 322.46K 262.54K 270.33K 281.45K 323.73K 617.60K 376.29K 338.82K 323.60K 339.89K 497.71K 391.52K 416.46K 203.52K 278.96K 229.25K
Prudential Financial 213.60K 253.04K 286.51K 220.94K 281.24K 308.15K 106.28K 100.48K 17.59K 15.20K 16.40K 16.40K 16.40K 16.40K 10.60K — — 186.94K 178.44K 359.69K
JPMorgan Chase & Co 211.34K — 21.11K 17.29K 20.25K 48.35K 136.90K 48.49K 17.99K 30.20K 27.19K 59 1.10K 1.10K 1.10K 2.85K 2.23K 142.88K 143.50K 148.94K
Fidelity Management & Research (FMR) 211.44K 191.83K 163.87K 145.28K 132.36K 127.17K 131.85K 118.27K 93.08K 91.69K 56.07K 64.38K 63.92K 63.92K 63.91K 64.31K 64.75K 64.69K — —
Franklin Resources 172.01K 215.39K 182.71K 173.70K 17.69K 78.17K 16.59K 15.97K — — 19.16K 19.16K 24.23K 24.23K 24.23K 24.23K 23.98K 35.60K — —
Two Sigma Investments 140.59K 13.00K 162.35K 56.13K 190.62K 192.80K 181.47K 49.55K 34.30K 81.69K 215.17K 107.74K 106.07K 208.15K 283.95K 83.61K 154.20K 166.45K — 15.92K
Charles Schwab Investment Management 128.24K 115.92K 125.37K 125.37K 127.44K 118.25K 117.67K 117.67K 126.24K 19.45K 19.45K 19.45K 19.45K 19.45K 19.45K — 28.82K 74.99K 80.65K 80.65K
Wellington Management Group 126.09K — — 149.55K — — — — — 170.76K — — — — — — — — — 550.70K

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