ORKA — ORUKA THERAPEUTICS INC
Reported value held$2.69B
Funds holding (latest)37
SectorHealth Care
Funds holding (Q2 2026)31
Institutional value$2.60B · 28.15M sh
New / Add / Cut / Exit7 / 19 / 5 / 2
Top-5 / Top-10 concentration75.4% / 91.1%
Institutional holdings change
Accumulating +45.8%
(+8.84M sh)
Institutional value change
Up +185.0%
As of Q2 2026, 31 SEC-registered investment managers reported holding ORKA (ORUKA THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $2.60B across 28.15M shares. That is +45.8% by share count (+8.84M shares) versus the previous quarter, while reported value moved +185.0%. Ownership is concentrated: the five largest holders account for 75.4% of reported value and the top ten for 91.1%.
Compared with the prior quarter, 7 opened new positions, 19 added to existing stakes, 5 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
ORKA is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 31 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | 9.06M | $862.02M | 0.04% | Add |
| BlackRock Inc history | 4.99M | $474.92M | 0.01% | Add |
| Capital World Investors history | 3.40M | $323.73M | 0.04% | New |
| Franklin Resources history | 1.62M | $154.31M | 0.04% | Add |
| Viking Global Investors history | 1.50M | $143.09M | 0.41% | Reduce |
| Geode Capital Management history | 1.43M | $136.11M | 0.01% | Add |
| Citadel Advisors history | 1.15M | $109.69M | 0.01% | Add |
| UBS Group AG history | 639.36K | $60.85M | 0.01% | Add |
| JPMorgan Chase & Co history | 655.03K | $60.74M | 0.01% | New |
| Charles Schwab Investment Management history | 433.40K | $41.25M | 0.01% | Add |
| Northern Trust Corp history | 428.89K | $40.82M | 0.01% | Add |
| MFS Investment Management history | 364.10K | $34.65M | 0.01% | New |
| Bank of America Corp history | 352.82K | $33.58M | 0.00% | Add |
| Deutsche Bank AG history | 195.20K | $18.58M | 0.01% | Add |
| Goldman Sachs Group history | 179.44K | $17.08M | 0.00% | Reduce |
| BNY Mellon history | 140.87K | $13.41M | 0.00% | Add |
| Invesco Ltd history | 124.66K | $11.86M | 0.00% | Add |
| Wellington Management Group history | 119.60K | $11.38M | 0.00% | Reduce |
| Prudential Financial history | 85.89K | $8.17M | 0.01% | Add |
| Morgan Stanley history | 76.36K | $7.27M | 0.00% | Reduce |
| Manulife Financial history | 68.42K | $6.51M | 0.01% | Reduce |
| Citigroup Inc history | 67.10K | $6.39M | 0.00% | Add |
| Wells Fargo & Co history | 51.92K | $4.94M | 0.00% | Add |
| Principal Global Investors history | 39.78K | $3.79M | 0.00% | New |
| Millennium Management history | 32.87K | $3.13M | 0.00% | New |
| Lazard Asset Management history | 32.19K | $3.06M | 0.01% | New |
| Legal & General Investment Management America history | 30.20K | $2.87M | 0.00% | Add |
| AQR Capital Management history | 18.70K | $1.78M | 0.00% | Add |
| Balyasny Asset Management history | 11.59K | $1.10M | 0.00% | New |
| PNC Financial Services history | 4.22K | $402.09K | 0.00% | Add |
| T. Rowe Price Associates history | 838.60K | $79.81K | 0.01% | Add |
Q1 2026 — 26 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | 7.43M | $364.51M | 0.02% | Add |
| BlackRock Inc history | 3.53M | $173.00M | 0.00% | Hold |
| Viking Global Investors history | 2.67M | $130.80M | 0.37% | Hold |
| Citadel Advisors history | 1.02M | $49.96M | 0.01% | Add |
| Franklin Resources history | 1.00M | $49.25M | 0.01% | Add |
| Geode Capital Management history | 954.87K | $46.85M | 0.00% | Add |
| Charles Schwab Investment Management history | 321.95K | $15.79M | 0.00% | Reduce |
| Northern Trust Corp history | 299.04K | $14.67M | 0.00% | Add |
| Goldman Sachs Group history | 246.71K | $12.10M | 0.00% | Add |
| UBS Group AG history | 212.27K | $10.41M | 0.00% | Reduce |
| Morgan Stanley history | 175.45K | $8.61M | 0.00% | Add |
| Deutsche Bank AG history | 140.79K | $6.91M | 0.00% | Add |
| Wellington Management Group history | 121.22K | $5.95M | 0.00% | Add |
| BNY Mellon history | 106.88K | $5.24M | 0.00% | Reduce |
| Bank of America Corp history | 100.09K | $4.91M | 0.00% | Reduce |
| Invesco Ltd history | 97.04K | $4.76M | 0.00% | Reduce |
| Manulife Financial history | 72.56K | $3.56M | 0.00% | Add |
| Two Sigma Investments history | 19.36K | $949.80K | 0.00% | Reduce |
| Legal & General Investment Management America history | 15.92K | $780.78K | 0.00% | Reduce |
| Wells Fargo & Co history | 14.83K | $727.46K | 0.00% | Reduce |
| Janus Henderson Group history | 12.10K | $593.93K | 0.00% | Hold |
| Citigroup Inc history | 10.39K | $509.48K | 0.00% | Add |
| Prudential Financial history | 6.04K | $296.26K | 0.00% | New |
| AQR Capital Management history | 4.21K | $206.35K | 0.00% | New |
| PNC Financial Services history | 3.19K | $156.27K | 0.00% | Add |
| T. Rowe Price Associates history | 727.45K | $35.68K | 0.00% | Add |
Q4 2025 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | 7.26M | $220.09M | 0.01% | Hold |
| BlackRock Inc history | 3.54M | $107.28M | 0.00% | Add |
| Viking Global Investors history | 2.67M | $80.83M | 0.21% | Hold |
| Vanguard Group history | 2.45M | $74.37M | 0.00% | Add |
| Geode Capital Management history | 942.51K | $28.57M | 0.00% | Add |
| Franklin Resources history | 938.42K | $28.44M | 0.01% | Reduce |
| Citadel Advisors history | 726.12K | $22.01M | 0.00% | Add |
| Point72 Asset Management history | 600.00K | $18.19M | 0.02% | Reduce |
| Charles Schwab Investment Management history | 329.50K | $9.99M | 0.00% | Add |
| Northern Trust Corp history | 280.90K | $8.51M | 0.00% | Add |
| UBS Group AG history | 271.01K | $8.21M | 0.00% | Add |
| Invesco Ltd history | 143.12K | $4.34M | 0.00% | Add |
| Bank of America Corp history | 139.27K | $4.22M | 0.00% | Add |
| Morgan Stanley history | 122.20K | $3.70M | 0.00% | Reduce |
| Deutsche Bank AG history | 119.33K | $3.62M | 0.00% | Add |
| BNY Mellon history | 114.17K | $3.46M | 0.00% | Add |
| Goldman Sachs Group history | 93.00K | $2.82M | 0.00% | Add |
| Wellington Management Group history | 84.72K | $2.57M | 0.00% | Reduce |
| D. E. Shaw & Co history | 76.42K | $2.32M | 0.00% | Reduce |
| Manulife Financial history | 61.36K | $1.80M | 0.00% | Add |
| Millennium Management history | 58.72K | $1.78M | 0.00% | New |
| Wells Fargo & Co history | 43.26K | $1.31M | 0.00% | Add |
| Two Sigma Investments history | 28.57K | $865.84K | 0.00% | Hold |
| JPMorgan Chase & Co history | 20.42K | $618.84K | 0.00% | Add |
| Legal & General Investment Management America history | 18.74K | $568.13K | 0.00% | Add |
| Janus Henderson Group history | 12.10K | $366.81K | 0.00% | New |
| Citigroup Inc history | 9.83K | $297.89K | 0.00% | Add |
| PNC Financial Services history | 1.45K | $43.95K | 0.00% | Reduce |
| T. Rowe Price Associates history | 649.35K | $19.68K | 0.00% | Add |
| Balyasny Asset Management history | 536 | $16.25K | 0.00% | New |
Q3 2025 — 27 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | 7.26M | $139.56M | 0.01% | Add |
| Viking Global Investors history | 2.67M | $51.28M | 0.13% | New |
| BlackRock Inc history | 2.20M | $42.39M | 0.00% | Add |
| Vanguard Group history | 1.78M | $34.17M | 0.00% | Reduce |
| Franklin Resources history | 1.07M | $20.49M | 0.01% | Add |
| Point72 Asset Management history | 1.04M | $19.94M | 0.04% | Add |
| Geode Capital Management history | 689.97K | $13.27M | 0.00% | Reduce |
| Citadel Advisors history | 329.39K | $6.33M | 0.00% | New |
| Charles Schwab Investment Management history | 246.93K | $4.75M | 0.00% | Add |
| Northern Trust Corp history | 219.71K | $4.23M | 0.00% | Reduce |
| Morgan Stanley history | 134.83K | $2.59M | 0.00% | Reduce |
| D. E. Shaw & Co history | 95.42K | $1.83M | 0.00% | Add |
| Wellington Management Group history | 91.09K | $1.75M | 0.00% | New |
| UBS Group AG history | 86.56K | $1.66M | 0.00% | Reduce |
| Bank of America Corp history | 79.00K | $1.52M | 0.00% | Add |
| BNY Mellon history | 70.63K | $1.36M | 0.00% | Add |
| Manulife Financial history | 51.91K | $998.19K | 0.00% | Reduce |
| Two Sigma Investments history | 28.57K | $549.32K | 0.00% | Reduce |
| Deutsche Bank AG history | 22.12K | $425.35K | 0.00% | Add |
| Wells Fargo & Co history | 20.86K | $401.06K | 0.00% | Add |
| Goldman Sachs Group history | 19.77K | $380.27K | 0.00% | Reduce |
| Invesco Ltd history | 16.32K | $313.80K | 0.00% | Add |
| JPMorgan Chase & Co history | 14.48K | $278.43K | 0.00% | Reduce |
| Citigroup Inc history | 3.37K | $64.83K | 0.00% | Reduce |
| Legal & General Investment Management America history | 2.48K | $47.63K | 0.00% | Hold |
| PNC Financial Services history | 2.01K | $38.73K | 0.00% | New |
| T. Rowe Price Associates history | 626.81K | $12.05K | 0.00% | Add |
Q2 2025 — 25 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | 5.62M | $62.96M | 0.00% | Add |
| BlackRock Inc history | 1.99M | $22.30M | 0.00% | Add |
| Vanguard Group history | 1.82M | $20.37M | 0.00% | Add |
| Franklin Resources history | 1.01M | $11.36M | 0.00% | Add |
| Geode Capital Management history | 707.41K | $7.93M | 0.00% | Add |
| Point72 Asset Management history | 330.00K | $3.70M | 0.01% | Reduce |
| Northern Trust Corp history | 222.18K | $2.49M | 0.00% | Add |
| Morgan Stanley history | 208.33K | $2.34M | 0.00% | Reduce |
| UBS Group AG history | 110.65K | $1.24M | 0.00% | Add |
| Charles Schwab Investment Management history | 84.00K | $941.66K | 0.00% | Add |
| Goldman Sachs Group history | 72.25K | $809.91K | 0.00% | Reduce |
| D. E. Shaw & Co history | 67.64K | $758.30K | 0.00% | New |
| BNY Mellon history | 63.51K | $711.94K | 0.00% | New |
| Manulife Financial history | 52.75K | $591.29K | 0.00% | Add |
| Two Sigma Investments history | 32.34K | $362.55K | 0.00% | Add |
| Deutsche Bank AG history | 19.36K | $217.04K | 0.00% | New |
| Bank of America Corp history | 18.85K | $211.30K | 0.00% | Add |
| Wells Fargo & Co history | 17.45K | $195.67K | 0.00% | New |
| JPMorgan Chase & Co history | 15.43K | $172.91K | 0.00% | Add |
| Invesco Ltd history | 15.31K | $171.63K | 0.00% | New |
| Renaissance Technologies history | 13.90K | $155.82K | 0.00% | Reduce |
| Millennium Management history | 12.33K | $138.17K | 0.00% | Reduce |
| Citigroup Inc history | 9.84K | $110.31K | 0.00% | Add |
| Legal & General Investment Management America history | 2.48K | $27.77K | 0.00% | New |
| T. Rowe Price Associates history | 410.88K | $4.61K | 0.00% | Hold |
Q1 2025 — 20 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Fidelity Management & Research (FMR) history | 5.56M | $57.06M | 0.00% | Add |
| Vanguard Group history | 1.64M | $16.80M | 0.00% | Add |
| BlackRock Inc history | 747.67K | $7.67M | 0.00% | Hold |
| Franklin Resources history | 720.55K | $7.39M | 0.00% | Hold |
| Morgan Stanley history | 527.79K | $5.42M | 0.00% | Add |
| Geode Capital Management history | 352.58K | $3.62M | 0.00% | Add |
| Point72 Asset Management history | 342.40K | $3.51M | 0.01% | Reduce |
| Goldman Sachs Group history | 244.20K | $2.51M | 0.00% | New |
| Wellington Management Group history | 87.50K | $897.76K | 0.00% | Reduce |
| Northern Trust Corp history | 59.59K | $611.34K | 0.00% | Reduce |
| Millennium Management history | 54.13K | $555.33K | 0.00% | Add |
| Manulife Financial history | 42.92K | $440.35K | 0.00% | Add |
| Renaissance Technologies history | 35.80K | $367.31K | 0.00% | New |
| UBS Group AG history | 33.88K | $347.64K | 0.00% | Add |
| Two Sigma Investments history | 21.83K | $223.99K | 0.00% | New |
| Charles Schwab Investment Management history | 15.61K | $160.14K | 0.00% | Hold |
| Bank of America Corp history | 4.86K | $49.90K | 0.00% | Add |
| JPMorgan Chase & Co history | 2.31K | $23.70K | 0.00% | Reduce |
| Citigroup Inc history | 1.55K | $15.94K | 0.00% | Reduce |
| T. Rowe Price Associates history | 411.60K | $4.22K | 0.00% | Reduce |
New Positions (Q2 2026)
- Capital World Investors 3.40M sh · $323.73M
- JPMorgan Chase & Co 655.03K sh · $60.74M
- MFS Investment Management 364.10K sh · $34.65M
- Principal Global Investors 39.78K sh · $3.79M
- Millennium Management 32.87K sh · $3.13M
- Lazard Asset Management 32.19K sh · $3.06M
- Balyasny Asset Management 11.59K sh · $1.10M
Fully Exited (vs previous quarter)
- Two Sigma Investments sold 19.36K sh · $949.80K
- Janus Henderson Group sold 12.10K sh · $593.93K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 |
|---|---|---|---|---|---|---|---|---|
| Fidelity Management & Research (FMR) | 9.06M | 7.43M | 7.26M | 7.26M | 5.62M | 5.56M | 5.51M | 4.68M |
| BlackRock Inc | 4.99M | 3.53M | 3.54M | 2.20M | 1.99M | 747.67K | 751.43K | 21.57K |
| Capital World Investors | 3.40M | — | — | — | — | — | — | — |
| Franklin Resources | 1.62M | 1.00M | 938.42K | 1.07M | 1.01M | 720.55K | 720.55K | 720.55K |
| Viking Global Investors | 1.50M | 2.67M | 2.67M | 2.67M | — | — | — | — |
| Geode Capital Management | 1.43M | 954.87K | 942.51K | 689.97K | 707.41K | 352.58K | 342.42K | 13.98K |
| Citadel Advisors | 1.15M | 1.02M | 726.12K | 329.39K | — | — | — | — |
| UBS Group AG | 639.36K | 212.27K | 271.01K | 86.56K | 110.65K | 33.88K | 25.16K | — |
| JPMorgan Chase & Co | 655.03K | — | 20.42K | 14.48K | 15.43K | 2.31K | 2.80K | — |
| Charles Schwab Investment Management | 433.40K | 321.95K | 329.50K | 246.93K | 84.00K | 15.61K | 15.61K | — |
| Northern Trust Corp | 428.89K | 299.04K | 280.90K | 219.71K | 222.18K | 59.59K | 64.04K | — |
| MFS Investment Management | 364.10K | — | — | — | — | — | — | — |
| Bank of America Corp | 352.82K | 100.09K | 139.27K | 79.00K | 18.85K | 4.86K | 198 | 15 |
| Deutsche Bank AG | 195.20K | 140.79K | 119.33K | 22.12K | 19.36K | — | — | — |
| Goldman Sachs Group | 179.44K | 246.71K | 93.00K | 19.77K | 72.25K | 244.20K | — | — |
| BNY Mellon | 140.87K | 106.88K | 114.17K | 70.63K | 63.51K | — | — | — |
| Invesco Ltd | 124.66K | 97.04K | 143.12K | 16.32K | 15.31K | — | — | — |
| Wellington Management Group | 119.60K | 121.22K | 84.72K | 91.09K | — | 87.50K | 95.09K | 82.14K |
| Prudential Financial | 85.89K | 6.04K | — | — | — | — | — | — |
| Morgan Stanley | 76.36K | 175.45K | 122.20K | 134.83K | 208.33K | 527.79K | 406.00K | 68.13K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details