OPK — OPKO HEALTH INC
Reported value held$170.82M
Funds holding (latest)39
SectorHealth Care
Funds holding (Q2 2026)25
Institutional value$116.51M · 78.12M sh
New / Add / Cut / Exit2 / 15 / 7 / 3
Top-5 / Top-10 concentration82.9% / 95.4%
Institutional holdings change
Accumulating +0.1%
(+61.17K sh)
Institutional value change
Up +31.6%
As of Q2 2026, 25 SEC-registered investment managers reported holding OPK (OPKO HEALTH INC) in their latest 13F filings, with a combined reported value of $116.51M across 78.12M shares. That is +0.1% by share count (+61.17K shares) versus the previous quarter, while reported value moved +31.6%. Ownership is concentrated: the five largest holders account for 82.9% of reported value and the top ten for 95.4%.
Compared with the prior quarter, 2 opened new positions, 15 added to existing stakes, 7 trimmed, 3 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
OPK is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 25 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 36.98M | $55.47M | 0.00% | Add |
| Geode Capital Management history | 11.58M | $17.38M | 0.00% | Add |
| Goldman Sachs Group history | 7.04M | $10.55M | 0.00% | Reduce |
| UBS Group AG history | 5.01M | $7.51M | 0.00% | Reduce |
| Northern Trust Corp history | 3.76M | $5.63M | 0.00% | Add |
| Charles Schwab Investment Management history | 3.60M | $5.40M | 0.00% | Add |
| Morgan Stanley history | 1.98M | $2.96M | 0.00% | Add |
| Citadel Advisors history | 1.59M | $2.38M | 0.00% | Reduce |
| BNY Mellon history | 1.33M | $1.99M | 0.00% | Add |
| AQR Capital Management history | 1.24M | $1.86M | 0.00% | Add |
| Bank of America Corp history | 795.72K | $1.19M | 0.00% | Reduce |
| Invesco Ltd history | 685.08K | $1.03M | 0.00% | Reduce |
| Deutsche Bank AG history | 398.60K | $597.90K | 0.00% | Add |
| Wells Fargo & Co history | 354.04K | $531.06K | 0.00% | Add |
| Legal & General Investment Management America history | 346.79K | $520.18K | 0.00% | Add |
| Citigroup Inc history | 199.82K | $299.74K | 0.00% | Add |
| Two Sigma Investments history | 175.80K | $263.70K | 0.00% | Add |
| JPMorgan Chase & Co history | 168.31K | $254.14K | 0.00% | New |
| Point72 Asset Management history | 145.23K | $217.85K | 0.00% | Add |
| Manulife Financial history | 119.13K | $178.70K | 0.00% | Reduce |
| Millennium Management history | 72.30K | $108.45K | 0.00% | New |
| Prudential Financial history | 68.98K | $103.46K | 0.00% | Add |
| PNC Financial Services history | 37.00K | $55.50K | 0.00% | Hold |
| Fidelity Management & Research (FMR) history | 15.34K | $23.00K | 0.00% | Reduce |
| T. Rowe Price Associates history | 455.75K | $684 | 0.00% | Add |
Q1 2026 — 26 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 36.23M | $41.30M | 0.00% | Add |
| Geode Capital Management history | 11.30M | $12.89M | 0.00% | Add |
| Goldman Sachs Group history | 7.68M | $8.75M | 0.00% | Add |
| UBS Group AG history | 6.07M | $6.92M | 0.00% | Add |
| Northern Trust Corp history | 3.62M | $4.13M | 0.00% | Add |
| Charles Schwab Investment Management history | 3.57M | $4.07M | 0.00% | Reduce |
| Citadel Advisors history | 2.24M | $2.55M | 0.00% | Reduce |
| BNY Mellon history | 1.28M | $1.46M | 0.00% | Reduce |
| Morgan Stanley history | 1.20M | $1.36M | 0.00% | Add |
| Bank of America Corp history | 1.14M | $1.30M | 0.00% | Add |
| Invesco Ltd history | 793.17K | $904.21K | 0.00% | Add |
| AQR Capital Management history | 763.59K | $870.49K | 0.00% | Reduce |
| Deutsche Bank AG history | 370.95K | $422.88K | 0.00% | Add |
| Legal & General Investment Management America history | 343.47K | $391.56K | 0.00% | Reduce |
| Janus Henderson Group history | 206.31K | $236.23K | 0.00% | Hold |
| Two Sigma Investments history | 170.00K | $193.80K | 0.00% | Reduce |
| Wells Fargo & Co history | 162.61K | $185.37K | 0.00% | Reduce |
| Manulife Financial history | 122.13K | $139.23K | 0.00% | Reduce |
| Renaissance Technologies history | 109.54K | $124.88K | 0.00% | New |
| Point72 Asset Management history | 93.33K | $106.40K | 0.00% | New |
| Prudential Financial history | 65.56K | $74.73K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 41.34K | $47.13K | 0.00% | Add |
| PNC Financial Services history | 37.00K | $42.18K | 0.00% | Hold |
| Citigroup Inc history | 33.68K | $38.39K | 0.00% | Add |
| Principal Global Investors history | 17.74K | $20.22K | 0.00% | Hold |
| T. Rowe Price Associates history | 404.65K | $462 | 0.00% | Add |
Q4 2025 — 28 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 34.85M | $43.91M | 0.00% | Add |
| Vanguard Group history | 32.46M | $40.90M | 0.00% | Reduce |
| Geode Capital Management history | 11.06M | $13.94M | 0.00% | Add |
| Goldman Sachs Group history | 5.99M | $7.54M | 0.00% | Add |
| UBS Group AG history | 5.35M | $6.74M | 0.00% | Add |
| Charles Schwab Investment Management history | 3.69M | $4.65M | 0.00% | Reduce |
| Northern Trust Corp history | 3.44M | $4.33M | 0.00% | Reduce |
| Citadel Advisors history | 3.00M | $3.78M | 0.00% | Add |
| AQR Capital Management history | 2.03M | $2.55M | 0.00% | Reduce |
| BNY Mellon history | 1.31M | $1.65M | 0.00% | Add |
| Morgan Stanley history | 917.35K | $1.16M | 0.00% | Add |
| Invesco Ltd history | 781.67K | $984.91K | 0.00% | Reduce |
| Two Sigma Investments history | 734.75K | $925.78K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 579.78K | $730.52K | 0.00% | Add |
| Wells Fargo & Co history | 468.52K | $590.33K | 0.00% | Add |
| Legal & General Investment Management America history | 453.26K | $571.12K | 0.00% | Add |
| Deutsche Bank AG history | 325.89K | $410.62K | 0.00% | Add |
| Millennium Management history | 265.27K | $334.24K | 0.00% | New |
| Manulife Financial history | 229.59K | $289.28K | 0.00% | Reduce |
| Janus Henderson Group history | 206.31K | $258.92K | 0.00% | Hold |
| Balyasny Asset Management history | 198.82K | $250.51K | 0.00% | New |
| PNC Financial Services history | 37.00K | $46.62K | 0.00% | Reduce |
| Prudential Financial history | 26.37K | $33.22K | 0.00% | Reduce |
| Principal Global Investors history | 17.75K | $22.37K | 0.00% | Reduce |
| Citigroup Inc history | 16.54K | $20.84K | 0.00% | Reduce |
| Bank of America Corp history | 16.00K | $20.61K | 0.00% | Hold |
| Fidelity Management & Research (FMR) history | 14.09K | $17.75K | 0.00% | Reduce |
| T. Rowe Price Associates history | 367.19K | $463 | 0.00% | Add |
Q3 2025 — 27 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 37.54M | $58.18M | 0.00% | Reduce |
| BlackRock Inc history | 33.17M | $51.42M | 0.00% | Add |
| Geode Capital Management history | 10.99M | $17.04M | 0.00% | Add |
| UBS Group AG history | 4.78M | $7.40M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 3.77M | $5.84M | 0.00% | Add |
| Northern Trust Corp history | 3.66M | $5.67M | 0.00% | Add |
| AQR Capital Management history | 2.87M | $4.45M | 0.00% | Add |
| Goldman Sachs Group history | 2.39M | $3.70M | 0.00% | Reduce |
| BNY Mellon history | 1.28M | $1.98M | 0.00% | Add |
| Two Sigma Investments history | 1.26M | $1.95M | 0.00% | Reduce |
| Invesco Ltd history | 1.02M | $1.58M | 0.00% | Reduce |
| Morgan Stanley history | 837.60K | $1.30M | 0.00% | Reduce |
| JPMorgan Chase & Co history | 527.41K | $817.49K | 0.00% | Reduce |
| Citadel Advisors history | 483.88K | $750.01K | 0.00% | Reduce |
| Legal & General Investment Management America history | 386.84K | $598.21K | 0.00% | Add |
| Wells Fargo & Co history | 342.49K | $530.85K | 0.00% | Add |
| Deutsche Bank AG history | 275.19K | $426.54K | 0.00% | Add |
| Manulife Financial history | 236.72K | $366.92K | 0.00% | Add |
| Janus Henderson Group history | 206.31K | $318.75K | 0.00% | Hold |
| Renaissance Technologies history | 59.70K | $92.53K | 0.00% | Add |
| PNC Financial Services history | 57.05K | $88.43K | 0.00% | Hold |
| Prudential Financial history | 54.77K | $84.90K | 0.00% | Add |
| Citigroup Inc history | 32.75K | $50.76K | 0.00% | Reduce |
| Principal Global Investors history | 28.74K | $44.54K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 16.56K | $25.67K | 0.00% | Add |
| Bank of America Corp history | 16.00K | $24.15K | 0.00% | Hold |
| T. Rowe Price Associates history | 343.29K | $533 | 0.00% | Reduce |
Q2 2025 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 38.24M | $50.48M | 0.00% | Add |
| BlackRock Inc history | 31.45M | $41.51M | 0.00% | Add |
| Geode Capital Management history | 10.42M | $13.76M | 0.00% | Add |
| UBS Group AG history | 5.72M | $7.55M | 0.00% | Add |
| Northern Trust Corp history | 3.48M | $4.60M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 3.35M | $4.42M | 0.00% | Add |
| Marshall Wace history | 3.35M | $4.42M | 0.01% | Reduce |
| Goldman Sachs Group history | 2.82M | $3.72M | 0.00% | Reduce |
| Morgan Stanley history | 2.06M | $2.72M | 0.00% | Reduce |
| Two Sigma Investments history | 1.84M | $2.42M | 0.01% | Add |
| Invesco Ltd history | 1.37M | $1.81M | 0.00% | Reduce |
| BNY Mellon history | 1.15M | $1.52M | 0.00% | Add |
| AQR Capital Management history | 935.90K | $1.24M | 0.00% | Reduce |
| Millennium Management history | 695.78K | $918.43K | 0.00% | Reduce |
| Citadel Advisors history | 691.20K | $912.38K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 584.00K | $796.30K | 0.00% | Add |
| Legal & General Investment Management America history | 355.68K | $469.50K | 0.00% | Add |
| Wells Fargo & Co history | 271.09K | $357.85K | 0.00% | Add |
| Deutsche Bank AG history | 239.02K | $315.50K | 0.00% | Reduce |
| Janus Henderson Group history | 206.31K | $271.30K | 0.00% | Hold |
| Citigroup Inc history | 167.11K | $220.59K | 0.00% | Reduce |
| Manulife Financial history | 138.64K | $183.01K | 0.00% | Add |
| PNC Financial Services history | 56.80K | $74.98K | 0.00% | Hold |
| Prudential Financial history | 46.84K | $61.83K | 0.00% | Add |
| Norges Bank Investment Management history | 39.48K | $52.11K | 0.00% | Reduce |
| Renaissance Technologies history | 38.10K | $50.29K | 0.00% | New |
| Principal Global Investors history | 24.77K | $32.70K | 0.00% | Add |
| Bank of America Corp history | 16.00K | $21.43K | 0.00% | Hold |
| Fidelity Management & Research (FMR) history | 16.12K | $21.28K | 0.00% | Reduce |
| T. Rowe Price Associates history | 437.51K | $578 | 0.00% | Reduce |
Q1 2025 — 32 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 29.50M | $48.97M | 0.00% | Add |
| BlackRock Inc history | 27.60M | $45.82M | 0.00% | Reduce |
| Geode Capital Management history | 8.43M | $14.00M | 0.00% | Add |
| Millennium Management history | 6.39M | $10.60M | 0.01% | Add |
| Marshall Wace history | 4.90M | $8.13M | 0.01% | Add |
| D. E. Shaw & Co history | 4.73M | $7.85M | 0.01% | New |
| Morgan Stanley history | 4.11M | $6.82M | 0.00% | Add |
| Goldman Sachs Group history | 4.00M | $6.64M | 0.00% | Add |
| Northern Trust Corp history | 3.53M | $5.86M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 2.74M | $4.55M | 0.00% | Reduce |
| Citadel Advisors history | 2.56M | $4.26M | 0.00% | Reduce |
| UBS Group AG history | 2.42M | $4.01M | 0.00% | Reduce |
| Two Sigma Investments history | 1.65M | $2.73M | 0.01% | Hold |
| Invesco Ltd history | 1.62M | $2.70M | 0.00% | Add |
| AQR Capital Management history | 1.61M | $2.67M | 0.00% | Add |
| BNY Mellon history | 1.02M | $1.69M | 0.00% | Hold |
| Legal & General Investment Management America history | 350.10K | $581.16K | 0.00% | Reduce |
| Deutsche Bank AG history | 281.65K | $467.53K | 0.00% | Reduce |
| Citigroup Inc history | 263.90K | $438.08K | 0.00% | Reduce |
| Wells Fargo & Co history | 230.01K | $381.82K | 0.00% | Hold |
| Janus Henderson Group history | 206.31K | $351.76K | 0.00% | Hold |
| Manulife Financial history | 124.73K | $207.05K | 0.00% | Reduce |
| Balyasny Asset Management history | 84.20K | $139.76K | 0.00% | Add |
| PNC Financial Services history | 56.80K | $94.29K | 0.00% | Hold |
| JPMorgan Chase & Co history | 44.00K | $73.28K | 0.00% | Reduce |
| Prudential Financial history | 26.77K | $44.43K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 24.39K | $40.48K | 0.00% | Hold |
| Principal Global Investors history | 21.12K | $35.07K | 0.00% | Add |
| Bank of America Corp history | 16.00K | $25.69K | 0.00% | Reduce |
| CPP Investments history | 12.90K | $21.41K | 0.00% | New |
| Lazard Asset Management history | 3.61M | $5.99K | 0.01% | Add |
| T. Rowe Price Associates history | 501.67K | $833 | 0.00% | Add |
New Positions (Q2 2026)
- JPMorgan Chase & Co 168.31K sh · $254.14K
- Millennium Management 72.30K sh · $108.45K
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 206.31K sh · $236.23K
- Renaissance Technologies sold 109.54K sh · $124.88K
- Principal Global Investors sold 17.74K sh · $20.22K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | 36.98M | 36.23M | 34.85M | 33.17M | 31.45M | 27.60M | 28.17M | 28.60M | — | — | — | — | — | — | — | — | — | — | — | — |
| Geode Capital Management | 11.58M | 11.30M | 11.06M | 10.99M | 10.42M | 8.43M | 8.39M | 8.37M | 8.82M | 9.97M | 9.72M | 9.13M | 8.74M | 8.41M | 7.99M | 7.83M | 7.63M | 7.77M | 7.73M | 7.73M |
| Goldman Sachs Group | 7.04M | 7.68M | 5.99M | 2.39M | 2.82M | 4.00M | 3.84M | 2.74M | 3.10M | 3.12M | 2.91M | 2.17M | 2.64M | 2.40M | 3.79M | 2.81M | 2.62M | 3.00M | 3.86M | 5.08M |
| UBS Group AG | 5.01M | 6.07M | 5.35M | 4.78M | 5.72M | 2.42M | 4.82M | 846.42K | 666.12K | 1.04M | 1.41M | 1.01M | 450.46K | 310.17K | 224.17K | 218.54K | 171.49K | 879.39K | 721.45K | 817.28K |
| Northern Trust Corp | 3.76M | 3.62M | 3.44M | 3.66M | 3.48M | 3.53M | 3.70M | 3.53M | 4.10M | 4.77M | 5.03M | 4.52M | 4.46M | 3.88M | 3.85M | 3.91M | 5.07M | 5.73M | 6.24M | 6.31M |
| Charles Schwab Investment Management | 3.60M | 3.57M | 3.69M | 3.77M | 3.35M | 2.74M | 3.50M | 4.21M | 5.05M | 5.81M | 5.73M | 5.55M | 5.14M | 4.85M | 4.37M | 3.81M | 3.39M | 3.87M | 3.57M | 3.55M |
| Morgan Stanley | 1.98M | 1.20M | 917.35K | 837.60K | 2.06M | 4.11M | 3.17M | 1.33M | 796.68K | 1.30M | 1.87M | 1.44M | 1.41M | 1.38M | 1.10M | 1.35M | 1.36M | 2.62M | 861.40K | 1.12M |
| Citadel Advisors | 1.59M | 2.24M | 3.00M | 483.88K | 691.20K | 2.56M | 4.94M | 4.34M | 1.45M | 757.59K | 749.35K | 467.89K | 428.80K | 461.33K | 1.39M | 1.21M | 1.30M | 744.12K | 1.79M | 909.97K |
| BNY Mellon | 1.33M | 1.28M | 1.31M | 1.28M | 1.15M | 1.02M | 1.02M | 1.06M | 1.39M | 1.47M | 1.61M | 1.58M | 1.59M | 1.54M | 1.54M | 2.04M | 1.92M | 2.12M | 2.12M | 1.95M |
| AQR Capital Management | 1.24M | 763.59K | 2.03M | 2.87M | 935.90K | 1.61M | 283.92K | 77.15K | 79.84K | 99.44K | 326.65K | 175.63K | — | 40.77K | 78.34K | 331.25K | 168.85K | 594.98K | 154.26K | 300.51K |
| Bank of America Corp | 795.72K | 1.14M | 16.00K | 16.00K | 16.00K | 16.00K | 581.58K | 298.74K | 258.61K | 394.82K | 408.06K | 290.89K | 292.43K | 581.88K | 1.14M | 149.56K | 150.93K | 1.80M | 1.80M | 219.37K |
| Invesco Ltd | 685.08K | 793.17K | 781.67K | 1.02M | 1.37M | 1.62M | 1.55M | 6.03M | 6.57M | 1.56M | 5.49M | 5.16M | 1.29M | 1.26M | 728.81K | 3.37M | 2.67M | 2.58M | 440.51K | 2.64M |
| Deutsche Bank AG | 398.60K | 370.95K | 325.89K | 275.19K | 239.02K | 281.65K | 309.87K | 209.00K | 160.27K | 196.77K | 951.12K | 228.87K | 1.62M | 1.74M | 2.32M | 2.28M | 1.53M | 274.54K | 325.10K | 331.97K |
| Wells Fargo & Co | 354.04K | 162.61K | 468.52K | 342.49K | 271.09K | 230.01K | 229.26K | 199.52K | 198.56K | 202.43K | 185.81K | 171.12K | 259.38K | 175.27K | 70.77K | 73.39K | 83.11K | 470.23K | 685.66K | 1.02M |
| Legal & General Investment Management America | 346.79K | 343.47K | 453.26K | 386.84K | 355.68K | 350.10K | 370.44K | 445.62K | 468.41K | 418.60K | 418.60K | 418.60K | 422.81K | 424.40K | 398.98K | 376.34K | 347.20K | 350.25K | 343.54K | 347.37K |
| Citigroup Inc | 199.82K | 33.68K | 16.54K | 32.75K | 167.11K | 263.90K | 270.11K | 238.83K | 130.92K | 1.52M | 1.55M | 1.48M | 1.62M | 1.50M | 2.13M | 2.14M | 2.17M | 279.95K | 745.73K | 613.49K |
| Two Sigma Investments | 175.80K | 170.00K | 734.75K | 1.26M | 1.84M | 1.65M | 1.65M | 697.90K | 606.49K | 1.63M | 968.82K | 1.44M | 1.59M | 1.92M | 2.27M | 2.89M | 1.70M | — | — | 17.80K |
| JPMorgan Chase & Co | 168.31K | — | 579.78K | 527.41K | 584.00K | 44.00K | 284.40K | 284.40K | 284.40K | 1.59M | 140.00K | 140.00K | 140.00K | 755.35K | 2.70K | 600 | 700 | 700 | 19.80K | 22.20K |
| Point72 Asset Management | 145.23K | 93.33K | — | — | — | — | — | — | — | — | — | 1.22M | 1.54M | 31.45K | — | — | — | 589.10K | 6.65M | — |
| Manulife Financial | 119.13K | 122.13K | 229.59K | 236.72K | 138.64K | 124.73K | 130.78K | 134.97K | 138.02K | 164.46K | 234.89K | 241.22K | 169.53K | 166.25K | 174.34K | 170.75K | 172.62K | 172.45K | 208.47K | 212.58K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details