HoldingsHub
中文

Home › Stocks › IONS

IONS — IONIS PHARMACEUTICALS INC

Reported value held$5.11B
Funds holding (latest)51
SectorHealth Care
Funds holding (Q2 2026)42
Institutional value$3.79B · 111.99M sh
New / Add / Cut / Exit1 / 17 / 22 / 3
Top-5 / Top-10 concentration74.1% / 86.2%
Institutional holdings change Reducing -45.8% (-94.56M sh)
Institutional value change Up +12.5%

As of Q2 2026, 42 SEC-registered investment managers reported holding IONS (IONIS PHARMACEUTICALS INC) in their latest 13F filings, with a combined reported value of $3.79B across 111.99M shares. That is -45.8% by share count (-94.56M shares) versus the previous quarter, while reported value moved +12.5%. Ownership is concentrated: the five largest holders account for 74.1% of reported value and the top ten for 86.2%.

Compared with the prior quarter, 1 opened new positions, 17 added to existing stakes, 22 trimmed, 3 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

IONS is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

FundQuarterSharesValuePortfolio WeightChange
Capital World Investors history Q2 2026 21.67M $1.72B 0.21% Add
Vanguard Group history Q4 2025 16.44M $1.30B 0.02% Hold
Two Sigma Investments history Q2 2026 6.25M $495.75M 0.38% Add
Geode Capital Management history Q2 2026 3.58M $294.75M 0.02% Reduce
Goldman Sachs Group history Q2 2026 2.11M $167.30M 0.01% Reduce
Franklin Resources history Q2 2026 1.62M $128.72M 0.03% Add
Charles Schwab Investment Management history Q2 2026 1.61M $127.26M 0.02% Add
Morgan Stanley history Q2 2026 1.28M $101.61M 0.01% Add
Invesco Ltd history Q2 2026 1.12M $88.86M 0.01% Reduce
Northern Trust Corp history Q2 2026 913.61K $72.44M 0.01% Add
Citadel Advisors history Q2 2026 855.28K $67.82M 0.01% Reduce
Bank of America Corp history Q2 2026 790.99K $62.72M 0.00% Reduce
MFS Investment Management history Q2 2026 651.82K $51.68M 0.02% Reduce
Arrowstreet Capital history Q2 2026 632.03K $50.11M 0.02% Reduce
Renaissance Technologies history Q2 2026 559.41K $44.36M 0.06% Add
Millennium Management history Q2 2026 546.37K $43.32M 0.02% Reduce
BNY Mellon history Q2 2026 542.45K $43.01M 0.01% Add
D. E. Shaw & Co history Q2 2026 384.54K $30.49M 0.02% Reduce
Balyasny Asset Management history Q2 2026 17.50M $27.22M 0.04% Reduce
Capital Research Global Investors history Q2 2026 331.94K $26.32M 0.00% Add

View all 51 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ3 2021Q4 2021Q1 2022Q2 2022Q3 2022Q4 2022Q1 2023Q2 2023Q3 2023Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Capital World Investors — — — — — — — 839.46K 839.46K 839.46K 839.46K 2.25M 7.83M 11.47M 12.36M 12.54M 12.72M 17.96M 21.19M 21.67M
Two Sigma Investments 314.13K 594.88K 780.26K 560.03K 292.99K 201.27K 23.08K 213.37K 476.06K 801.45K 1.08M 1.03M 919.08K 921.44K 1.69M 1.79M 1.58M 20.00M 5.86M 6.25M
Geode Capital Management 1.77M 1.83M 1.90M 1.87M 1.90M 2.01M 2.07M 2.16M 2.19M 2.28M 2.36M 2.48M 2.67M 2.69M 2.84M 2.89M 3.07M 3.15M 3.98M 3.58M
Goldman Sachs Group 601.84K 589.30K 954.33K 1.04M 1.29M 947.41K 422.10K 188.37K 346.73K 441.38K 224.38K 371.81K 335.71K 478.21K 652.52K 777.94K 810.00K 2.00M 2.46M 2.11M
Franklin Resources — — — — 11.25K 13.72K 10.40K 9.17K 8.45K 13.71K 9.81K 10.02K 10.15K 13.30K — 5.56K 6.59K 1.32M 1.58M 1.62M
Charles Schwab Investment Management 1.07M 1.09M 1.14M 1.15M 1.20M 1.26M 1.19M 1.20M 1.24M 1.28M 1.30M 1.33M 1.44M 1.48M 1.44M 1.49M 1.52M 1.54M 1.58M 1.61M
Morgan Stanley 384.00K 20.00K 20.00K 3.72M 1.55M 5.40M 5.72M 6.58M 7.09M 6.74M 6.74M 31.00K 1.30M 1.07M 17.66M 15.03M 12.78M 80.00K 94.00K 1.28M
Invesco Ltd 141.35K 132.24K 139.99K 261.00K 261.00K 261.00K 261.00K 261.00K 261.00K 261.00K 2.91M 1.65M 1.50M 1.50M 1.50M 256.24K 519.07K 1.50M 1.28M 1.12M
Northern Trust Corp 655.42K 660.89K 648.53K 625.47K 623.64K 639.69K 658.47K 671.08K 690.72K 687.99K 692.25K 717.98K 742.90K 840.27K 834.85K 814.25K 844.94K 846.72K 868.18K 913.61K
Citadel Advisors 1.17M 1.34M 1.31M 551.34K 15.06M 454.05K 197.52K 790.28K 2.00M 318.73K 253.83K 12.22M 497.65K 2.26M 3.62M 1.64M 2.59M 2.31M 58.00M 855.28K
Bank of America Corp 710.12K 612.84K 797.16K 61.00K 165.00K 6.75M 632.64K 459.32K 536.04K 455.08K 618.10K 514.54K 4.83M 1.54M 1.82M 1.41M 2.27M 6.76M 980.00K 790.99K
MFS Investment Management — — — — — — 27.15K 26.53K 5.77K 5.59K 5.58K — — — — 519.18K 862.59K 812.75K 666.12K 651.82K
Arrowstreet Capital 41.10K — — 41.10K — — — — — — — — — — — — 630.14K 1.06M 737.86K 632.03K
Renaissance Technologies 97.71K 230.81K 134.91K 614.81K 867.71K 1.18M 636.31K 370.50K 269.80K 112.41K 179.71K 249.51K 190.51K 205.51K 153.51K 270.71K 486.71K 223.61K 305.55K 559.41K
Millennium Management 282.85K 1.62M 191.19K 320.62K 18.93K 115.51K 45.36K 418.91K 437.12K 890.33K 583.18K 128.22K 430.72K 774.22K 635.37K 2.65M 779.57K 93.26K 1.05M 546.37K
BNY Mellon 1.06M 1.06M 1.05M 965.32K 879.41K 600.00K 866.10K 857.75K 1.43M 1.44M 1.38M 847.48K 860.89K 916.07K 844.63K 727.19K 832.11K 753.89K 514.62K 542.45K
D. E. Shaw & Co 126.11K 160.66K 45.48M 126.62K 209.44K 299.23K 86.65K 196.21K 362.05K 119.16K 160.48K 190.78K 145.09K 23.12K 28.00M 28.00M 25.50M 332.80K 429.60K 384.54K
Balyasny Asset Management 15.00M 455.62K — 155.53K — — 203.47K 125.85K — — — 1.08M — — 260.00K 1.03M 1.02M 381.18K 35.00M 17.50M
Capital Research Global Investors — — — — — — — — — — — — — — — — — — 323.01K 331.94K
ARK Invest 8.51M 7.08M 6.17M 4.70M 3.71M 2.67M 2.64M 2.42M 2.37M 1.91M 1.40M 1.36M 1.38M 1.03M 1.00M 900.32K 631.22K 422.97K 288.72K 300.77K

Download holders (CSV)