HRTX — HERON THERAPEUTICS INC
As of Q2 2026, 26 SEC-registered investment managers reported holding HRTX (HERON THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $14.18M across 33.32M shares. That is -6.3% by share count (-2.24M shares) versus the previous quarter, while reported value moved -50.0%. Ownership is concentrated: the five largest holders account for 73.0% of reported value and the top ten for 93.6%.
Compared with the prior quarter, 3 opened new positions, 11 added to existing stakes, 9 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
HRTX is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 26 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 10.55M | $4.50M | 0.00% | Add |
| Geode Capital Management history | 4.27M | $1.82M | 0.00% | Add |
| Millennium Management history | 4.07M | $1.74M | 0.00% | Reduce |
| UBS Group AG history | 3.00M | $1.28M | 0.00% | Add |
| Marshall Wace history | 2.35M | $1.01M | 0.00% | New |
| AQR Capital Management history | 1.55M | $663.19K | 0.00% | Add |
| Renaissance Technologies history | 1.51M | $643.14K | 0.00% | Reduce |
| Goldman Sachs Group history | 1.33M | $567.54K | 0.00% | Add |
| Northern Trust Corp history | 1.22M | $522.18K | 0.00% | Add |
| Charles Schwab Investment Management history | 1.22M | $519.61K | 0.00% | Reduce |
| Invesco Ltd history | 406.67K | $173.56K | 0.00% | Add |
| BNY Mellon history | 395.84K | $168.94K | 0.00% | Reduce |
| Two Sigma Investments history | 266.31K | $113.66K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 226.80K | $96.80K | 0.00% | Add |
| Wells Fargo & Co history | 152.92K | $65.27K | 0.00% | Add |
| D. E. Shaw & Co history | 120.44K | $51.40K | 0.00% | Reduce |
| Morgan Stanley history | 111.70K | $47.67K | 0.00% | Reduce |
| Bank of America Corp history | 108.37K | $46.16K | 0.00% | Reduce |
| Deutsche Bank AG history | 96.30K | $41.41K | 0.00% | Add |
| JPMorgan Chase & Co history | 75.67K | $32.95K | 0.00% | New |
| Citigroup Inc history | 74.94K | $31.98K | 0.00% | Add |
| Citadel Advisors history | 47.10K | $20.10K | 0.00% | Reduce |
| Prudential Financial history | 23.50K | $10.03K | 0.00% | Hold |
| Legal & General Investment Management America history | 13.93K | $5.95K | 0.00% | Hold |
| Principal Global Investors history | 12.07K | $5.15K | 0.00% | New |
| T. Rowe Price Associates history | 111.50K | $48 | 0.00% | Hold |
Q1 2026 — 24 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 10.11M | $8.09M | 0.00% | Reduce |
| Millennium Management history | 7.63M | $6.11M | 0.00% | Add |
| Geode Capital Management history | 4.01M | $3.21M | 0.00% | Reduce |
| D. E. Shaw & Co history | 2.60M | $2.08M | 0.00% | Reduce |
| UBS Group AG history | 2.29M | $1.83M | 0.00% | Add |
| Renaissance Technologies history | 1.72M | $1.37M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 1.38M | $1.10M | 0.00% | Reduce |
| Northern Trust Corp history | 1.17M | $938.14K | 0.00% | Add |
| Goldman Sachs Group history | 1.06M | $845.66K | 0.00% | Add |
| Citadel Advisors history | 814.87K | $651.98K | 0.00% | Reduce |
| AQR Capital Management history | 641.59K | $513.33K | 0.00% | Add |
| Morgan Stanley history | 513.41K | $410.78K | 0.00% | Reduce |
| BNY Mellon history | 406.81K | $325.49K | 0.00% | Reduce |
| Invesco Ltd history | 326.51K | $261.24K | 0.00% | Add |
| Two Sigma Investments history | 317.40K | $253.95K | 0.00% | Reduce |
| Bank of America Corp history | 160.98K | $128.78K | 0.00% | Add |
| Deutsche Bank AG history | 93.08K | $74.47K | 0.00% | Hold |
| Wells Fargo & Co history | 66.54K | $53.24K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 58.20K | $46.56K | 0.00% | Reduce |
| Manulife Financial history | 45.99K | $36.80K | 0.00% | Reduce |
| Prudential Financial history | 23.50K | $18.80K | 0.00% | New |
| Legal & General Investment Management America history | 13.93K | $11.14K | 0.00% | Reduce |
| Citigroup Inc history | 7.24K | $5.79K | 0.00% | Add |
| T. Rowe Price Associates history | 111.50K | $90 | 0.00% | Add |
Q4 2025 — 25 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 10.22M | $13.28M | 0.00% | Add |
| Vanguard Group history | 9.82M | $12.77M | 0.00% | Add |
| Millennium Management history | 7.17M | $9.32M | 0.00% | Add |
| Geode Capital Management history | 4.08M | $5.31M | 0.00% | Add |
| D. E. Shaw & Co history | 3.00M | $3.91M | 0.00% | Reduce |
| Citadel Advisors history | 2.14M | $2.78M | 0.00% | Reduce |
| UBS Group AG history | 2.09M | $2.72M | 0.00% | Reduce |
| Renaissance Technologies history | 1.92M | $2.49M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 1.42M | $1.84M | 0.00% | Add |
| Northern Trust Corp history | 1.09M | $1.42M | 0.00% | Reduce |
| Two Sigma Investments history | 999.51K | $1.30M | 0.00% | Add |
| Goldman Sachs Group history | 989.69K | $1.29M | 0.00% | Reduce |
| Morgan Stanley history | 963.85K | $1.25M | 0.00% | Reduce |
| BNY Mellon history | 418.48K | $544.02K | 0.00% | Add |
| AQR Capital Management history | 376.30K | $489.19K | 0.00% | Reduce |
| Invesco Ltd history | 307.86K | $400.22K | 0.00% | Add |
| Wells Fargo & Co history | 179.62K | $233.51K | 0.00% | Add |
| Bank of America Corp history | 134.44K | $174.78K | 0.00% | Reduce |
| Deutsche Bank AG history | 93.08K | $121.00K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 84.20K | $109.46K | 0.00% | Add |
| JPMorgan Chase & Co history | 62.40K | $81.11K | 0.00% | Reduce |
| Manulife Financial history | 48.66K | $63.26K | 0.00% | Reduce |
| Legal & General Investment Management America history | 14.24K | $18.51K | 0.00% | Hold |
| Citigroup Inc history | 3.48K | $4.52K | 0.00% | Reduce |
| T. Rowe Price Associates history | 76.64K | $100 | 0.00% | Hold |
Q3 2025 — 29 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 9.99M | $12.58M | 0.00% | Reduce |
| Vanguard Group history | 8.46M | $10.66M | 0.00% | Hold |
| Geode Capital Management history | 3.64M | $4.59M | 0.00% | Add |
| D. E. Shaw & Co history | 3.09M | $3.89M | 0.00% | Reduce |
| UBS Group AG history | 2.93M | $3.70M | 0.00% | Reduce |
| Renaissance Technologies history | 2.85M | $3.60M | 0.01% | Add |
| Citadel Advisors history | 2.77M | $3.49M | 0.00% | Add |
| Citigroup Inc history | 2.48M | $3.12M | 0.00% | Add |
| Morgan Stanley history | 2.47M | $3.11M | 0.00% | Reduce |
| AQR Capital Management history | 1.94M | $2.44M | 0.00% | Add |
| Goldman Sachs Group history | 1.32M | $1.67M | 0.00% | Add |
| Marshall Wace history | 1.31M | $1.65M | 0.00% | Reduce |
| JPMorgan Chase & Co history | 1.29M | $1.63M | 0.00% | Add |
| Charles Schwab Investment Management history | 1.28M | $1.61M | 0.00% | Add |
| Northern Trust Corp history | 1.16M | $1.46M | 0.00% | Hold |
| Bank of America Corp history | 732.07K | $922.41K | 0.00% | Reduce |
| Two Sigma Investments history | 692.28K | $872.27K | 0.00% | Reduce |
| Wellington Management Group history | 525.77K | $662.48K | 0.00% | Add |
| BNY Mellon history | 412.47K | $519.72K | 0.00% | Add |
| Millennium Management history | 248.50K | $313.11K | 0.00% | Reduce |
| Invesco Ltd history | 231.40K | $291.56K | 0.00% | Add |
| Wells Fargo & Co history | 123.13K | $155.15K | 0.00% | Reduce |
| Deutsche Bank AG history | 85.16K | $107.30K | 0.00% | Add |
| Manulife Financial history | 51.97K | $65.48K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 47.39K | $59.72K | 0.00% | Reduce |
| Prudential Financial history | 34.47K | $43.43K | 0.00% | Reduce |
| Legal & General Investment Management America history | 14.24K | $17.94K | 0.00% | Hold |
| Principal Global Investors history | 11.65K | $14.68K | 0.00% | Reduce |
| T. Rowe Price Associates history | 76.64K | $97 | 0.00% | Reduce |
Q2 2025 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 10.10M | $20.91M | 0.00% | Add |
| Vanguard Group history | 8.47M | $17.54M | 0.00% | Add |
| Geode Capital Management history | 3.57M | $7.38M | 0.00% | Add |
| D. E. Shaw & Co history | 3.20M | $6.62M | 0.01% | Add |
| UBS Group AG history | 3.18M | $6.59M | 0.00% | Add |
| Marshall Wace history | 2.89M | $5.99M | 0.01% | Add |
| Morgan Stanley history | 2.76M | $5.72M | 0.00% | Add |
| Renaissance Technologies history | 2.69M | $5.57M | 0.01% | Add |
| Citadel Advisors history | 2.26M | $4.68M | 0.00% | Add |
| Charles Schwab Investment Management history | 1.19M | $2.46M | 0.00% | Add |
| Northern Trust Corp history | 1.15M | $2.39M | 0.00% | Add |
| Bank of America Corp history | 1.08M | $2.23M | 0.00% | Add |
| Goldman Sachs Group history | 1.04M | $2.16M | 0.00% | Add |
| JPMorgan Chase & Co history | 953.08K | $1.97M | 0.00% | Add |
| Two Sigma Investments history | 940.58K | $1.95M | 0.00% | Reduce |
| Wellington Management Group history | 493.08K | $1.02M | 0.00% | Add |
| Millennium Management history | 492.34K | $1.02M | 0.00% | Reduce |
| BNY Mellon history | 402.11K | $832.37K | 0.00% | Add |
| Wells Fargo & Co history | 258.25K | $534.57K | 0.00% | Add |
| Manulife Financial history | 241.05K | $498.97K | 0.00% | Add |
| Invesco Ltd history | 173.08K | $358.28K | 0.00% | Add |
| Principal Global Investors history | 80.28K | $166.19K | 0.00% | Reduce |
| Deutsche Bank AG history | 67.73K | $140.20K | 0.00% | Reduce |
| AQR Capital Management history | 61.75K | $127.82K | 0.00% | Add |
| Citigroup Inc history | 51.95K | $107.54K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 51.32K | $106.23K | 0.00% | Add |
| Prudential Financial history | 36.47K | $75.48K | 0.00% | Add |
| Legal & General Investment Management America history | 14.24K | $29.47K | 0.00% | Add |
| T. Rowe Price Associates history | 2.88M | $5.97K | 0.00% | Reduce |
| PNC Financial Services history | 173 | $358 | 0.00% | Hold |
Q1 2025 — 34 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 8.56M | $18.84M | 0.00% | Hold |
| Vanguard Group history | 8.23M | $18.10M | 0.00% | Add |
| Point72 Asset Management history | 4.78M | $10.51M | 0.03% | Add |
| Geode Capital Management history | 3.11M | $6.85M | 0.00% | Add |
| D. E. Shaw & Co history | 2.99M | $6.57M | 0.01% | Reduce |
| Renaissance Technologies history | 2.27M | $5.00M | 0.01% | Add |
| Morgan Stanley history | 1.93M | $4.25M | 0.00% | Reduce |
| Millennium Management history | 1.40M | $3.07M | 0.00% | Add |
| Marshall Wace history | 1.25M | $2.76M | 0.00% | Add |
| Charles Schwab Investment Management history | 1.09M | $2.40M | 0.00% | Reduce |
| Two Sigma Investments history | 1.05M | $2.32M | 0.01% | Add |
| Goldman Sachs Group history | 1.03M | $2.26M | 0.00% | Add |
| Northern Trust Corp history | 995.39K | $2.19M | 0.00% | Reduce |
| Bank of America Corp history | 968.04K | $2.13M | 0.00% | Reduce |
| JPMorgan Chase & Co history | 696.44K | $1.53M | 0.00% | Add |
| Citadel Advisors history | 551.29K | $1.21M | 0.00% | Add |
| Wellington Management Group history | 487.24K | $1.07M | 0.00% | Hold |
| BNY Mellon history | 328.34K | $722.35K | 0.00% | Reduce |
| Manulife Financial history | 229.33K | $504.53K | 0.00% | Add |
| UBS Group AG history | 158.74K | $349.23K | 0.00% | Hold |
| Invesco Ltd history | 119.66K | $263.26K | 0.00% | Add |
| Principal Global Investors history | 115.32K | $253.70K | 0.00% | Add |
| Deutsche Bank AG history | 85.61K | $188.34K | 0.00% | Add |
| Citigroup Inc history | 81.84K | $180.05K | 0.00% | Reduce |
| Franklin Resources history | 77.55K | $170.61K | 0.00% | Add |
| Wells Fargo & Co history | 77.17K | $169.77K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 50.77K | $111.70K | 0.00% | Reduce |
| AQR Capital Management history | 27.31K | $60.08K | 0.00% | Reduce |
| Balyasny Asset Management history | 11.49K | $25.28K | 0.00% | New |
| Prudential Financial history | 11.02K | $24.23K | 0.00% | New |
| Legal & General Investment Management America history | 10.43K | $22.95K | 0.00% | Hold |
| T. Rowe Price Associates history | 3.00M | $6.61K | 0.00% | Add |
| PNC Financial Services history | 173 | $381 | 0.00% | Add |
| Lazard Asset Management history | 13.81K | $30 | 0.00% | New |
New Positions (Q2 2026)
- Marshall Wace 2.35M sh · $1.01M
- JPMorgan Chase & Co 75.67K sh · $32.95K
- Principal Global Investors 12.07K sh · $5.15K
Fully Exited (vs previous quarter)
- Manulife Financial sold 45.99K sh · $36.80K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | 10.55M | 10.11M | 10.22M | 9.99M | 10.10M | 8.56M | 8.59M | 8.53M | — | — | — | — | — | — | — | — | — | — | — | — |
| Geode Capital Management | 4.27M | 4.01M | 4.08M | 3.64M | 3.57M | 3.11M | 3.02M | 3.05M | 3.11M | 2.80M | 2.62M | 2.40M | 2.05M | 1.97M | 1.96M | 1.83M | 1.81M | 1.64M | 1.71M | 1.61M |
| Millennium Management | 4.07M | 7.63M | 7.17M | 248.50K | 492.34K | 1.40M | 215.53K | 934.39K | 1.43M | 3.17M | 1.24M | 76.69K | 93.79K | 565.79K | 3.51M | 1.68M | 431.64K | 1.20M | 1.00M | — |
| UBS Group AG | 3.00M | 2.29M | 2.09M | 2.93M | 3.18M | 158.74K | 159.48K | 85.25K | 166.79K | 111.39K | 121.48K | 63.07K | 69.04K | 55.77K | 36.89K | 87.89K | 8.06K | 234.12K | 319.26K | 248.11K |
| Marshall Wace | 2.35M | — | — | 1.31M | 2.89M | 1.25M | 1.02M | 1.72M | 1.76M | 494.35K | — | — | — | — | — | — | — | — | — | — |
| AQR Capital Management | 1.55M | 641.59K | 376.30K | 1.94M | 61.75K | 27.31K | 214.96K | 900.11K | 607.13K | 38.90K | 36.85K | 122.77K | 147.95K | 141.08K | 51.36K | 53.27K | — | — | — | — |
| Renaissance Technologies | 1.51M | 1.72M | 1.92M | 2.85M | 2.69M | 2.27M | 1.19M | 2.01M | 1.99M | 2.41M | 1.88M | 291.30K | 1.06M | 1.14M | 326.50K | — | — | — | — | — |
| Goldman Sachs Group | 1.33M | 1.06M | 989.69K | 1.32M | 1.04M | 1.03M | 655.16K | 1.71M | 1.42M | 1.40M | 984.65K | 605.81K | 566.06K | 404.31K | 1.15M | 2.30M | 1.27M | 2.28M | 1.92M | 1.60M |
| Northern Trust Corp | 1.22M | 1.17M | 1.09M | 1.16M | 1.15M | 995.39K | 1.01M | 989.99K | 934.23K | 959.55K | 988.09K | 1.02M | 908.57K | 983.76K | 961.29K | 979.57K | 955.46K | 915.57K | 961.69K | 966.66K |
| Charles Schwab Investment Management | 1.22M | 1.38M | 1.42M | 1.28M | 1.19M | 1.09M | 1.11M | 1.10M | 1.14M | 1.09M | 997.20K | 983.01K | 743.58K | 731.13K | 798.04K | 741.01K | 731.05K | 715.31K | 696.26K | 696.53K |
| Invesco Ltd | 406.67K | 326.51K | 307.86K | 231.40K | 173.08K | 119.66K | 71.40K | 51.66K | 41.33K | 47.15K | 57.31K | 58.70K | 67.69K | 54.07K | 87.78K | 83.65K | 80.44K | 71.93K | 62.56K | 64.76K |
| BNY Mellon | 395.84K | 406.81K | 418.48K | 412.47K | 402.11K | 328.34K | 340.71K | 340.74K | 449.21K | 335.56K | 404.37K | 353.39K | 334.05K | 335.23K | 349.42K | 347.64K | 311.35K | 304.73K | 298.85K | 331.84K |
| Two Sigma Investments | 266.31K | 317.40K | 999.51K | 692.28K | 940.58K | 1.05M | 990.17K | 1.40M | 1.11M | 80.56K | — | — | 36.50K | 148.50K | 273.08K | 152.22K | 107.06K | — | — | — |
| Fidelity Management & Research (FMR) | 226.80K | 58.20K | 84.20K | 47.39K | 51.32K | 50.77K | 191.89K | 431.91K | 342.31K | 319.94K | 319.64K | 280.50K | 276.23K | 136.77K | 136.12K | 142.25K | 140.17K | 134.80K | 126.98K | 640.61K |
| Wells Fargo & Co | 152.92K | 66.54K | 179.62K | 123.13K | 258.25K | 77.17K | 74.76K | 61.20K | 60.60K | 41.36K | 37.35K | 30.51K | 52.28K | 30.85K | 9.98K | 13.75K | 45.84K | 101.09K | 104.11K | 169.09K |
| D. E. Shaw & Co | 120.44K | 2.60M | 3.00M | 3.09M | 3.20M | 2.99M | 3.72M | 4.38M | 3.86M | 2.70M | 1.29M | 245.27K | 348.96K | 721.08K | 787.08K | 899.57K | 1.61M | 2.03M | 1.35M | 1.43M |
| Morgan Stanley | 111.70K | 513.41K | 963.85K | 2.47M | 2.76M | 1.93M | 2.79M | 1.77M | 767.86K | 199.00K | 462.15K | 435.51K | 377.27K | 456.00K | 811.90K | 946.31K | 2.04M | 1.47M | 292.20K | 364.77K |
| Bank of America Corp | 108.37K | 160.98K | 134.44K | 732.07K | 1.08M | 968.04K | 1.05M | 955.93K | 434.30K | 235.04K | 186.48K | 91.78K | 60.59K | 106.01K | 115.60K | 566.86K | 726.94K | 1.61M | 345.24K | 106.54K |
| Deutsche Bank AG | 96.30K | 93.08K | 93.08K | 85.16K | 67.73K | 85.61K | 59.79K | 59.79K | 31.32K | 43.87K | 45.55K | 45.55K | 45.55K | 67.14K | 50.71K | 50.02K | 55.17K | 194.09K | 388.63K | 529.34K |
| JPMorgan Chase & Co | 75.67K | — | 62.40K | 1.29M | 953.08K | 696.44K | 562.76K | 206.71K | 52.22K | 42.48K | 75.62K | 6.81M | 6.86M | 7.01M | 6.75M | 6.69M | 100.00K | 6.13M | 6.25M | 5.30M |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details