FULC — FULCRUM THERAPEUTICS INC
Reported value held$152.09M
Funds holding (latest)37
SectorHealth Care
Funds holding (Q2 2026)31
Institutional value$107.98M · 29.60M sh
New / Add / Cut / Exit2 / 23 / 6 / 0
Top-5 / Top-10 concentration60.8% / 82.0%
Institutional holdings change
Accumulating +64.7%
(+11.63M sh)
Institutional value change
Down -21.3%
As of Q2 2026, 31 SEC-registered investment managers reported holding FULC (FULCRUM THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $107.98M across 29.60M shares. That is +64.7% by share count (+11.63M shares) versus the previous quarter, while reported value moved -21.3%. Ownership is concentrated: the five largest holders account for 60.8% of reported value and the top ten for 82.0%.
Compared with the prior quarter, 2 opened new positions, 23 added to existing stakes, 6 trimmed. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
FULC is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 31 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 8.82M | $32.30M | 0.00% | Add |
| D. E. Shaw & Co history | 3.04M | $11.14M | 0.01% | Add |
| Citadel Advisors history | 2.94M | $10.77M | 0.00% | Add |
| Renaissance Technologies history | 1.65M | $6.03M | 0.01% | Add |
| Millennium Management history | 1.49M | $5.44M | 0.00% | Add |
| Geode Capital Management history | 1.43M | $5.24M | 0.00% | Reduce |
| Marshall Wace history | 1.36M | $4.97M | 0.00% | New |
| UBS Group AG history | 1.25M | $4.59M | 0.00% | Add |
| AQR Capital Management history | 1.10M | $4.04M | 0.00% | Add |
| Goldman Sachs Group history | 1.09M | $4.01M | 0.00% | Add |
| Bank of America Corp history | 1.04M | $3.82M | 0.00% | Add |
| Two Sigma Investments history | 812.77K | $2.97M | 0.00% | Add |
| Balyasny Asset Management history | 692.37K | $2.53M | 0.00% | Reduce |
| Point72 Asset Management history | 651.43K | $2.38M | 0.00% | Reduce |
| Northern Trust Corp history | 487.87K | $1.79M | 0.00% | Add |
| Charles Schwab Investment Management history | 433.22K | $1.59M | 0.00% | Add |
| Wellington Management Group history | 285.08K | $1.04M | 0.00% | Add |
| Morgan Stanley history | 184.19K | $674.14K | 0.00% | Add |
| BNY Mellon history | 154.51K | $565.52K | 0.00% | Add |
| Invesco Ltd history | 113.32K | $414.75K | 0.00% | Add |
| CPP Investments history | 102.40K | $374.78K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 92.33K | $337.92K | 0.00% | Add |
| Citigroup Inc history | 62.77K | $229.75K | 0.00% | Add |
| Deutsche Bank AG history | 52.38K | $191.71K | 0.00% | Add |
| Wells Fargo & Co history | 49.70K | $181.89K | 0.00% | Add |
| JPMorgan Chase & Co history | 41.37K | $154.31K | 0.00% | New |
| Franklin Resources history | 34.06K | $124.67K | 0.00% | Reduce |
| Manulife Financial history | 16.72K | $61.19K | 0.00% | Add |
| Legal & General Investment Management America history | 5.25K | $19.22K | 0.00% | Reduce |
| T. Rowe Price Associates history | 94.23K | $345 | 0.00% | Add |
| PNC Financial Services history | 77 | $282 | 0.00% | Reduce |
Q1 2026 — 29 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 5.39M | $41.35M | 0.00% | Add |
| Balyasny Asset Management history | 2.18M | $16.72M | 0.02% | Add |
| Point72 Asset Management history | 2.07M | $15.91M | 0.02% | Reduce |
| D. E. Shaw & Co history | 1.62M | $12.45M | 0.01% | Reduce |
| Geode Capital Management history | 1.49M | $11.40M | 0.00% | Add |
| Citadel Advisors history | 1.35M | $10.36M | 0.00% | Add |
| Goldman Sachs Group history | 571.91K | $4.39M | 0.00% | Add |
| AQR Capital Management history | 543.16K | $4.17M | 0.00% | Add |
| Northern Trust Corp history | 472.99K | $3.63M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 426.87K | $3.27M | 0.00% | Add |
| Millennium Management history | 356.47K | $2.73M | 0.00% | Add |
| UBS Group AG history | 315.19K | $2.42M | 0.00% | Add |
| Morgan Stanley history | 173.34K | $1.33M | 0.00% | Add |
| BNY Mellon history | 149.94K | $1.15M | 0.00% | Add |
| Two Sigma Investments history | 139.00K | $1.07M | 0.00% | New |
| Bank of America Corp history | 126.56K | $970.71K | 0.00% | Reduce |
| Wellington Management Group history | 118.60K | $909.66K | 0.00% | Reduce |
| Invesco Ltd history | 111.12K | $852.33K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 61.04K | $468.18K | 0.00% | Add |
| Franklin Resources history | 54.67K | $419.29K | 0.00% | Add |
| Deutsche Bank AG history | 48.83K | $374.51K | 0.00% | Reduce |
| Citigroup Inc history | 23.43K | $179.75K | 0.00% | Reduce |
| Wells Fargo & Co history | 22.55K | $172.97K | 0.00% | Reduce |
| CPP Investments history | 18.40K | $141.13K | 0.00% | New |
| Legal & General Investment Management America history | 17.70K | $135.79K | 0.00% | Add |
| Manulife Financial history | 16.10K | $123.50K | 0.00% | Add |
| Renaissance Technologies history | 13.60K | $104.31K | 0.00% | Reduce |
| PNC Financial Services history | 885 | $6.79K | 0.00% | Reduce |
| T. Rowe Price Associates history | 80.17K | $615 | 0.00% | Add |
Q4 2025 — 31 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 4.26M | $48.22M | 0.00% | Add |
| Vanguard Group history | 3.56M | $40.26M | 0.00% | Add |
| Point72 Asset Management history | 2.40M | $27.12M | 0.03% | New |
| D. E. Shaw & Co history | 1.91M | $21.64M | 0.01% | Add |
| Citadel Advisors history | 1.30M | $14.74M | 0.00% | Add |
| Geode Capital Management history | 1.11M | $12.51M | 0.00% | Add |
| Balyasny Asset Management history | 970.44K | $10.98M | 0.01% | Reduce |
| Northern Trust Corp history | 552.22K | $6.25M | 0.00% | Reduce |
| Invesco Ltd history | 417.19K | $4.72M | 0.00% | Add |
| Charles Schwab Investment Management history | 388.90K | $4.40M | 0.00% | Add |
| Goldman Sachs Group history | 323.88K | $3.66M | 0.00% | Reduce |
| Deutsche Bank AG history | 287.10K | $3.25M | 0.00% | Add |
| Bank of America Corp history | 231.18K | $2.61M | 0.00% | Add |
| Wells Fargo & Co history | 166.40K | $1.88M | 0.00% | Add |
| Morgan Stanley history | 165.62K | $1.87M | 0.00% | Reduce |
| Wellington Management Group history | 146.43K | $1.66M | 0.00% | Reduce |
| BNY Mellon history | 116.91K | $1.32M | 0.00% | Reduce |
| UBS Group AG history | 102.97K | $1.16M | 0.00% | Reduce |
| Marshall Wace history | 102.92K | $1.16M | 0.00% | New |
| Principal Global Investors history | 97.69K | $1.10M | 0.00% | Add |
| Citigroup Inc history | 67.10K | $758.92K | 0.00% | Add |
| Millennium Management history | 54.43K | $615.62K | 0.00% | Reduce |
| Franklin Resources history | 44.25K | $500.46K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 20.79K | $235.12K | 0.00% | Add |
| Renaissance Technologies history | 17.40K | $196.79K | 0.00% | Reduce |
| Legal & General Investment Management America history | 16.37K | $185.18K | 0.00% | Hold |
| AQR Capital Management history | 15.50K | $175.33K | 0.00% | New |
| Manulife Financial history | 12.88K | $145.71K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 7.69K | $86.98K | 0.00% | Add |
| PNC Financial Services history | 1.44K | $16.31K | 0.00% | Add |
| T. Rowe Price Associates history | 63.76K | $722 | 0.00% | Reduce |
Q3 2025 — 28 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 3.71M | $34.10M | 0.00% | Reduce |
| Vanguard Group history | 3.00M | $27.60M | 0.00% | Reduce |
| Balyasny Asset Management history | 1.45M | $13.34M | 0.02% | Add |
| D. E. Shaw & Co history | 1.45M | $13.33M | 0.01% | Add |
| Geode Capital Management history | 1.00M | $9.24M | 0.00% | Reduce |
| Citadel Advisors history | 888.96K | $8.18M | 0.00% | Add |
| Goldman Sachs Group history | 586.35K | $5.39M | 0.00% | Reduce |
| Northern Trust Corp history | 568.32K | $5.23M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 333.48K | $3.07M | 0.00% | Reduce |
| UBS Group AG history | 301.16K | $2.77M | 0.00% | Add |
| Deutsche Bank AG history | 285.33K | $2.63M | 0.00% | Add |
| Renaissance Technologies history | 248.20K | $2.28M | 0.00% | Add |
| Morgan Stanley history | 243.84K | $2.24M | 0.00% | Reduce |
| Wellington Management Group history | 179.36K | $1.65M | 0.00% | Add |
| Millennium Management history | 150.87K | $1.39M | 0.00% | Add |
| Bank of America Corp history | 147.21K | $1.35M | 0.00% | Add |
| Invesco Ltd history | 123.87K | $1.14M | 0.00% | Reduce |
| BNY Mellon history | 119.16K | $1.10M | 0.00% | Reduce |
| Principal Global Investors history | 66.55K | $612.26K | 0.00% | New |
| Franklin Resources history | 60.02K | $552.20K | 0.00% | Hold |
| Wells Fargo & Co history | 32.51K | $299.06K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 18.07K | $166.24K | 0.00% | Reduce |
| Legal & General Investment Management America history | 16.37K | $150.63K | 0.00% | Reduce |
| Manulife Financial history | 13.95K | $128.32K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 7.35K | $67.62K | 0.00% | Add |
| PNC Financial Services history | 1.42K | $13.04K | 0.00% | Reduce |
| Citigroup Inc history | 718 | $6.61K | 0.00% | Reduce |
| T. Rowe Price Associates history | 65.89K | $607 | 0.00% | Reduce |
Q2 2025 — 31 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 4.38M | $30.13M | 0.00% | Reduce |
| Vanguard Group history | 3.15M | $21.65M | 0.00% | Reduce |
| Balyasny Asset Management history | 1.34M | $9.21M | 0.01% | New |
| Geode Capital Management history | 1.19M | $8.21M | 0.00% | Reduce |
| D. E. Shaw & Co history | 1.18M | $8.10M | 0.01% | Add |
| Goldman Sachs Group history | 1.14M | $7.87M | 0.00% | Add |
| Northern Trust Corp history | 611.54K | $4.21M | 0.00% | Reduce |
| Point72 Asset Management history | 498.22K | $3.43M | 0.01% | New |
| Invesco Ltd history | 470.33K | $3.24M | 0.00% | Add |
| Charles Schwab Investment Management history | 387.78K | $2.67M | 0.00% | Add |
| Morgan Stanley history | 314.41K | $2.16M | 0.00% | Add |
| Deutsche Bank AG history | 279.25K | $1.92M | 0.00% | Hold |
| Citadel Advisors history | 185.53K | $1.28M | 0.00% | Reduce |
| BNY Mellon history | 137.00K | $942.56K | 0.00% | Reduce |
| UBS Group AG history | 135.21K | $930.21K | 0.00% | Add |
| Wellington Management Group history | 126.40K | $869.65K | 0.00% | New |
| Millennium Management history | 105.69K | $727.17K | 0.00% | Add |
| Renaissance Technologies history | 78.50K | $540.08K | 0.00% | Reduce |
| Franklin Resources history | 60.02K | $412.95K | 0.00% | Add |
| Two Sigma Investments history | 58.97K | $405.68K | 0.00% | Reduce |
| Bank of America Corp history | 45.99K | $316.40K | 0.00% | Reduce |
| Wells Fargo & Co history | 33.75K | $232.19K | 0.00% | Add |
| JPMorgan Chase & Co history | 26.16K | $179.99K | 0.00% | Reduce |
| Citigroup Inc history | 21.02K | $144.59K | 0.00% | Reduce |
| Manulife Financial history | 19.89K | $136.82K | 0.00% | Reduce |
| AQR Capital Management history | 18.05K | $124.20K | 0.00% | Add |
| Legal & General Investment Management America history | 17.46K | $120.13K | 0.00% | Add |
| Prudential Financial history | 14.54K | $100.03K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 6.97K | $47.93K | 0.00% | Add |
| PNC Financial Services history | 1.45K | $9.97K | 0.00% | Add |
| T. Rowe Price Associates history | 69.03K | $475 | 0.00% | Reduce |
Q1 2025 — 28 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 4.71M | $13.57M | 0.00% | Reduce |
| Vanguard Group history | 3.22M | $9.27M | 0.00% | Reduce |
| Geode Capital Management history | 1.23M | $3.55M | 0.00% | Reduce |
| Northern Trust Corp history | 640.95K | $1.85M | 0.00% | Reduce |
| D. E. Shaw & Co history | 580.66K | $1.67M | 0.00% | Hold |
| Citadel Advisors history | 403.16K | $1.16M | 0.00% | Reduce |
| Goldman Sachs Group history | 402.60K | $1.16M | 0.00% | Reduce |
| Renaissance Technologies history | 401.10K | $1.16M | 0.00% | New |
| Charles Schwab Investment Management history | 381.36K | $1.10M | 0.00% | Reduce |
| Morgan Stanley history | 285.60K | $822.52K | 0.00% | Reduce |
| Deutsche Bank AG history | 279.81K | $805.86K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 209.89K | $604.49K | 0.00% | Add |
| Two Sigma Investments history | 150.27K | $432.79K | 0.00% | Reduce |
| BNY Mellon history | 143.59K | $413.54K | 0.00% | Add |
| Invesco Ltd history | 85.77K | $247.01K | 0.00% | Add |
| UBS Group AG history | 71.92K | $207.13K | 0.00% | Reduce |
| Bank of America Corp history | 56.13K | $161.67K | 0.00% | Reduce |
| Millennium Management history | 40.69K | $117.19K | 0.00% | Reduce |
| Citigroup Inc history | 37.83K | $108.95K | 0.00% | Reduce |
| Wells Fargo & Co history | 30.52K | $87.90K | 0.00% | Reduce |
| Franklin Resources history | 24.82K | $71.48K | 0.00% | Hold |
| Prudential Financial history | 22.73K | $65.45K | 0.00% | Hold |
| Manulife Financial history | 22.41K | $64.54K | 0.00% | Reduce |
| AQR Capital Management history | 17.61K | $50.71K | 0.00% | Reduce |
| Legal & General Investment Management America history | 5.29K | $15.23K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 4.32K | $12.44K | 0.00% | Reduce |
| PNC Financial Services history | 526 | $1.51K | 0.00% | Add |
| T. Rowe Price Associates history | 70.17K | $203 | 0.00% | Add |
New Positions (Q2 2026)
- Marshall Wace 1.36M sh · $4.97M
- JPMorgan Chase & Co 41.37K sh · $154.31K
Fully Exited (vs previous quarter)
No tracked fund fully exited this quarter.
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | 8.82M | 5.39M | 4.26M | 3.71M | 4.38M | 4.71M | 5.17M | 5.71M | — | — | — | — | — | — | — | — | — | — | — | — |
| D. E. Shaw & Co | 3.04M | 1.62M | 1.91M | 1.45M | 1.18M | 580.66K | 583.20K | 757.73K | 591.78K | 625.18K | 497.68K | 221.26K | 146.22K | 15.32K | 176.15K | 82.34K | 139.48K | 547.40K | 852.15K | 798.10K |
| Citadel Advisors | 2.94M | 1.35M | 1.30M | 888.96K | 185.53K | 403.16K | 474.72K | 1.75M | 1.92M | 1.38M | 1.74M | 1.62M | 1.86M | 587.06K | 1.16M | 988.63K | 557.75K | 185.80K | 207.36K | 354.71K |
| Renaissance Technologies | 1.65M | 13.60K | 17.40K | 248.20K | 78.50K | 401.10K | — | — | 13.26K | — | — | 52.73K | 344.81K | 390.10K | — | — | 68.00K | — | — | 133.90K |
| Millennium Management | 1.49M | 356.47K | 54.43K | 150.87K | 105.69K | 40.69K | 76.12K | 23.50K | 402.75K | 897.46K | 437.50K | 1.00M | 574.86K | 620.56K | — | — | 81.20K | 35.00K | 74.47K | 99.71K |
| Geode Capital Management | 1.43M | 1.49M | 1.11M | 1.00M | 1.19M | 1.23M | 1.29M | 1.32M | 1.31M | 563.46K | 553.23K | 534.50K | 565.81K | 1.06M | 855.83K | 625.07K | 566.51K | 530.14K | 498.00K | 458.44K |
| Marshall Wace | 1.36M | — | 102.92K | — | — | — | — | — | 333.16K | 225.57K | 505.10K | 1.05M | 17.40K | 121.00K | 15.53K | 20.11K | — | — | 13.51K | 151.69K |
| UBS Group AG | 1.25M | 315.19K | 102.97K | 301.16K | 135.21K | 71.92K | 77.39K | 80.63K | 190.55K | 72.77K | 30.18K | 11.16K | 31.76K | 424 | 3.79K | — | — | 1.47K | 825 | 1.30K |
| AQR Capital Management | 1.10M | 543.16K | 15.50K | — | 18.05K | 17.61K | 45.64K | 98.48K | — | — | — | — | — | — | — | — | 13.97K | — | 14.02K | — |
| Goldman Sachs Group | 1.09M | 571.91K | 323.88K | 586.35K | 1.14M | 402.60K | 542.26K | 927.96K | 560.49K | 810.27K | 871.50K | 259.23K | 387.73K | 297.81K | 315.43K | 344.73K | 284.31K | 237.64K | 84.88K | 62.50K |
| Bank of America Corp | 1.04M | 126.56K | 231.18K | 147.21K | 45.99K | 56.13K | 91.87K | 99.92K | 69.89K | 61.65K | 187.47K | 139.04K | 132.24K | 42.37K | 57.63K | 29.82K | 103.67K | 14.83K | 27.96K | 7.47K |
| Two Sigma Investments | 812.77K | 139.00K | — | — | 58.97K | 150.27K | 169.54K | 272.11K | 509.69K | 175.22K | 261.75K | 562.12K | 577.87K | 649.81K | 133.02K | — | 214.76K | 16.90K | 520.99K | 632.54K |
| Balyasny Asset Management | 692.37K | 2.18M | 970.44K | 1.45M | 1.34M | — | — | 10.37K | 11.37K | 15.71K | 105.18K | — | 11.09K | — | — | — | 15.68K | — | 11.73K | — |
| Point72 Asset Management | 651.43K | 2.07M | 2.40M | — | 498.22K | — | — | — | — | 223.40K | — | — | 1.90M | 2.64M | — | 1.49M | 1.99M | 325.00K | 505.65K | 140.00K |
| Northern Trust Corp | 487.87K | 472.99K | 552.22K | 568.32K | 611.54K | 640.95K | 710.32K | 567.74K | 166.89K | 136.43K | 144.97K | 142.98K | 143.43K | 451.95K | 390.48K | 311.29K | 308.29K | 256.93K | 263.07K | 257.87K |
| Charles Schwab Investment Management | 433.22K | 426.87K | 388.90K | 333.48K | 387.78K | 381.36K | 526.04K | 569.18K | 175.98K | 24.48K | 24.48K | 24.48K | 24.48K | 141.31K | 114.89K | 92.77K | 85.92K | 72.21K | 70.48K | 67.35K |
| Wellington Management Group | 285.08K | 118.60K | 146.43K | 179.36K | 126.40K | — | 172.16K | 176.16K | 182.73K | 172.66K | — | — | — | — | — | — | — | — | — | — |
| Morgan Stanley | 184.19K | 173.34K | 165.62K | 243.84K | 314.41K | 285.60K | 1.53M | 350.69K | 1.23M | 1.16M | 1.22M | 911.87K | 1.10M | 1.16M | 1.17M | 1.20M | 1.18M | 1.11M | 89.55K | 85.01K |
| BNY Mellon | 154.51K | 149.94K | 116.91K | 119.16K | 137.00K | 143.59K | 141.87K | 138.75K | 186.73K | — | 19.83K | 61.19K | 62.32K | 212.20K | 197.86K | 132.47K | 104.42K | 100.64K | 100.67K | 95.03K |
| Invesco Ltd | 113.32K | 111.12K | 417.19K | 123.87K | 470.33K | 85.77K | 29.98K | 30.66K | 31.04K | 496.68K | 476.21K | — | — | 12.47K | 12.98K | 11.24K | 11.10K | 223.46K | 107.47K | 596.06K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
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