EWTX — EDGEWISE THERAPEUTICS INC
Reported value held$1.26B
Funds holding (latest)39
SectorHealth Care
Funds holding (Q2 2026)30
Institutional value$919.06M · 23.43M sh
New / Add / Cut / Exit2 / 19 / 9 / 2
Top-5 / Top-10 concentration78.6% / 91.6%
Institutional holdings change
Reducing -3.8%
(-930.12K sh)
Institutional value change
Up +20.1%
As of Q2 2026, 30 SEC-registered investment managers reported holding EWTX (EDGEWISE THERAPEUTICS INC) in their latest 13F filings, with a combined reported value of $919.06M across 23.43M shares. That is -3.8% by share count (-930.12K shares) versus the previous quarter, while reported value moved +20.1%. Ownership is concentrated: the five largest holders account for 78.6% of reported value and the top ten for 91.6%.
Compared with the prior quarter, 2 opened new positions, 19 added to existing stakes, 9 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
EWTX is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 6.61M | $268.42M | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 5.49M | $223.02M | 0.01% | Add |
| Geode Capital Management history | 2.17M | $88.35M | 0.01% | Add |
| Morgan Stanley history | 1.95M | $79.17M | 0.00% | Reduce |
| Bank of America Corp history | 1.56M | $63.31M | 0.00% | Add |
| Northern Trust Corp history | 671.27K | $27.27M | 0.00% | Add |
| Charles Schwab Investment Management history | 620.53K | $25.21M | 0.00% | Add |
| Goldman Sachs Group history | 599.47K | $24.36M | 0.00% | Reduce |
| Citadel Advisors history | 530.81K | $21.57M | 0.00% | Add |
| Norges Bank Investment Management history | 510.14K | $20.73M | 0.00% | Reduce |
| Prudential Financial history | 260.73K | $10.59M | 0.01% | Add |
| Deutsche Bank AG history | 245.00K | $9.95M | 0.00% | Add |
| BNY Mellon history | 212.35K | $8.63M | 0.00% | Add |
| JPMorgan Chase & Co history | 203.15K | $8.48M | 0.00% | New |
| D. E. Shaw & Co history | 189.12K | $7.68M | 0.00% | Add |
| UBS Group AG history | 174.97K | $7.11M | 0.00% | Reduce |
| Point72 Asset Management history | 131.86K | $5.36M | 0.01% | Add |
| Invesco Ltd history | 120.93K | $4.91M | 0.00% | Reduce |
| Wells Fargo & Co history | 78.90K | $3.21M | 0.00% | Add |
| Citigroup Inc history | 59.56K | $2.42M | 0.00% | Add |
| Two Sigma Investments history | 49.55K | $2.01M | 0.00% | Reduce |
| Legal & General Investment Management America history | 44.69K | $1.82M | 0.00% | Add |
| Manulife Financial history | 40.76K | $1.66M | 0.00% | Add |
| Franklin Resources history | 37.60K | $1.53M | 0.00% | Reduce |
| Wellington Management Group history | 25.66K | $1.04M | 0.00% | Reduce |
| AQR Capital Management history | 18.46K | $749.87K | 0.00% | Add |
| Marshall Wace history | 6.10K | $247.84K | 0.00% | Reduce |
| Principal Global Investors history | 5.47K | $222.25K | 0.00% | New |
| T. Rowe Price Associates history | 816.52K | $33.18K | 0.00% | Add |
| PNC Financial Services history | 176 | $7.15K | 0.00% | Add |
Q1 2026 — 29 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 6.47M | $203.90M | 0.00% | Reduce |
| Janus Henderson Group history | 5.92M | $186.29M | 0.09% | Add |
| Morgan Stanley history | 2.25M | $70.75M | 0.00% | Reduce |
| Geode Capital Management history | 1.79M | $56.39M | 0.00% | Add |
| Bank of America Corp history | 1.33M | $41.81M | 0.00% | Reduce |
| UBS Group AG history | 1.31M | $41.30M | 0.01% | Reduce |
| Fidelity Management & Research (FMR) history | 1.02M | $32.04M | 0.00% | Add |
| Marshall Wace history | 648.39K | $20.42M | 0.02% | Reduce |
| Goldman Sachs Group history | 629.82K | $19.84M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 596.31K | $18.78M | 0.00% | Reduce |
| Northern Trust Corp history | 576.56K | $18.16M | 0.00% | Add |
| Citadel Advisors history | 483.73K | $15.24M | 0.00% | Add |
| Millennium Management history | 342.87K | $10.80M | 0.01% | Add |
| Deutsche Bank AG history | 221.87K | $6.99M | 0.00% | Add |
| BNY Mellon history | 192.43K | $6.06M | 0.00% | Reduce |
| Invesco Ltd history | 138.40K | $4.36M | 0.00% | Add |
| D. E. Shaw & Co history | 104.86K | $3.30M | 0.00% | Reduce |
| Two Sigma Investments history | 50.85K | $1.60M | 0.00% | Hold |
| Legal & General Investment Management America history | 42.54K | $1.34M | 0.00% | Reduce |
| Franklin Resources history | 41.73K | $1.31M | 0.00% | Reduce |
| Manulife Financial history | 35.45K | $1.12M | 0.00% | Reduce |
| Wellington Management Group history | 27.41K | $863.38K | 0.00% | Reduce |
| Wells Fargo & Co history | 25.24K | $795.19K | 0.00% | Reduce |
| Citigroup Inc history | 18.52K | $583.29K | 0.00% | Reduce |
| Point72 Asset Management history | 14.60K | $459.90K | 0.00% | New |
| Prudential Financial history | 10.61K | $334.06K | 0.00% | New |
| AQR Capital Management history | 8.54K | $268.98K | 0.00% | Reduce |
| PNC Financial Services history | 172 | $5.42K | 0.00% | Add |
| T. Rowe Price Associates history | 69.43K | $2.19K | 0.00% | Add |
Q4 2025 — 32 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 6.63M | $164.54M | 0.00% | Add |
| Vanguard Group history | 4.87M | $120.89M | 0.00% | Add |
| Janus Henderson Group history | 4.57M | $113.33M | 0.05% | Reduce |
| Morgan Stanley history | 2.91M | $72.23M | 0.00% | Add |
| UBS Group AG history | 2.12M | $52.54M | 0.01% | Add |
| Geode Capital Management history | 1.75M | $43.34M | 0.00% | Add |
| Bank of America Corp history | 1.47M | $36.60M | 0.00% | Add |
| Goldman Sachs Group history | 788.17K | $19.56M | 0.00% | Add |
| Norges Bank Investment Management history | 751.36K | $18.64M | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 692.96K | $17.20M | 0.00% | Add |
| Marshall Wace history | 681.92K | $16.93M | 0.01% | New |
| Charles Schwab Investment Management history | 611.38K | $15.17M | 0.00% | Add |
| Northern Trust Corp history | 559.65K | $13.89M | 0.00% | Reduce |
| D. E. Shaw & Co history | 394.69K | $9.79M | 0.01% | Reduce |
| Citadel Advisors history | 223.30K | $5.54M | 0.00% | Add |
| Citigroup Inc history | 223.29K | $5.54M | 0.00% | Reduce |
| Deutsche Bank AG history | 214.77K | $5.33M | 0.00% | Add |
| BNY Mellon history | 198.61K | $4.93M | 0.00% | Reduce |
| Millennium Management history | 156.44K | $3.88M | 0.00% | Reduce |
| Balyasny Asset Management history | 151.91K | $3.77M | 0.01% | New |
| JPMorgan Chase & Co history | 146.04K | $3.62M | 0.00% | Add |
| Wellington Management Group history | 111.39K | $2.76M | 0.00% | Reduce |
| Wells Fargo & Co history | 75.44K | $1.87M | 0.00% | Add |
| Invesco Ltd history | 75.44K | $1.87M | 0.00% | Add |
| Legal & General Investment Management America history | 52.75K | $1.31M | 0.00% | Reduce |
| Two Sigma Investments history | 50.85K | $1.26M | 0.00% | Add |
| Franklin Resources history | 43.15K | $1.07M | 0.00% | Reduce |
| Manulife Financial history | 36.76K | $912.17K | 0.00% | Add |
| AQR Capital Management history | 13.75K | $341.11K | 0.00% | New |
| CPP Investments history | 3.90K | $96.78K | 0.00% | Reduce |
| PNC Financial Services history | 75 | $1.86K | 0.00% | Add |
| T. Rowe Price Associates history | 57.31K | $1.42K | 0.00% | Add |
Q3 2025 — 28 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 6.35M | $103.02M | 0.00% | Reduce |
| Janus Henderson Group history | 4.98M | $80.80M | 0.04% | Reduce |
| Vanguard Group history | 4.80M | $77.92M | 0.00% | Reduce |
| Geode Capital Management history | 1.72M | $27.86M | 0.00% | Reduce |
| Morgan Stanley history | 869.68K | $14.11M | 0.00% | Add |
| Millennium Management history | 725.42K | $11.77M | 0.01% | Reduce |
| D. E. Shaw & Co history | 677.56K | $10.99M | 0.01% | Add |
| Charles Schwab Investment Management history | 597.60K | $9.69M | 0.00% | Add |
| Northern Trust Corp history | 587.88K | $9.54M | 0.00% | Reduce |
| Citigroup Inc history | 538.45K | $8.73M | 0.00% | Reduce |
| Goldman Sachs Group history | 527.83K | $8.56M | 0.00% | Reduce |
| Bank of America Corp history | 321.13K | $5.21M | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 253.32K | $4.11M | 0.00% | Reduce |
| BNY Mellon history | 204.24K | $3.31M | 0.00% | Reduce |
| Deutsche Bank AG history | 154.90K | $2.51M | 0.00% | Add |
| Wellington Management Group history | 114.53K | $1.86M | 0.00% | Add |
| UBS Group AG history | 114.13K | $1.85M | 0.00% | Reduce |
| Citadel Advisors history | 87.62K | $1.42M | 0.00% | Reduce |
| JPMorgan Chase & Co history | 68.72K | $1.11M | 0.00% | Reduce |
| Invesco Ltd history | 66.06K | $1.07M | 0.00% | Add |
| Legal & General Investment Management America history | 55.94K | $907.36K | 0.00% | Add |
| Franklin Resources history | 48.22K | $782.13K | 0.00% | Add |
| Wells Fargo & Co history | 42.20K | $684.42K | 0.00% | Add |
| Manulife Financial history | 35.54K | $576.43K | 0.00% | Reduce |
| Two Sigma Investments history | 26.27K | $426.04K | 0.00% | New |
| CPP Investments history | 4.50K | $72.99K | 0.00% | Add |
| PNC Financial Services history | 67 | $1.09K | 0.00% | Add |
| T. Rowe Price Associates history | 51.39K | $834 | 0.00% | Add |
Q2 2025 — 28 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 6.78M | $88.90M | 0.00% | Add |
| Janus Henderson Group history | 5.50M | $72.13M | 0.04% | Add |
| Vanguard Group history | 4.84M | $63.47M | 0.00% | Add |
| Geode Capital Management history | 1.80M | $23.56M | 0.00% | Add |
| Millennium Management history | 921.97K | $12.09M | 0.01% | Add |
| Morgan Stanley history | 727.71K | $9.54M | 0.00% | Add |
| Citigroup Inc history | 724.90K | $9.50M | 0.01% | Add |
| Goldman Sachs Group history | 631.74K | $8.28M | 0.00% | Add |
| Northern Trust Corp history | 602.90K | $7.90M | 0.00% | Reduce |
| D. E. Shaw & Co history | 595.43K | $7.81M | 0.01% | Add |
| Charles Schwab Investment Management history | 579.10K | $7.59M | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 470.72K | $6.17M | 0.00% | Add |
| Citadel Advisors history | 398.75K | $5.23M | 0.00% | Add |
| Bank of America Corp history | 254.43K | $3.34M | 0.00% | Reduce |
| BNY Mellon history | 212.86K | $2.79M | 0.00% | Add |
| UBS Group AG history | 170.98K | $2.24M | 0.00% | Reduce |
| Deutsche Bank AG history | 147.53K | $1.93M | 0.00% | Reduce |
| Wellington Management Group history | 112.57K | $1.48M | 0.00% | Reduce |
| JPMorgan Chase & Co history | 77.62K | $1.02M | 0.00% | Add |
| Invesco Ltd history | 56.16K | $736.23K | 0.00% | Add |
| Legal & General Investment Management America history | 52.31K | $685.75K | 0.00% | Add |
| Norges Bank Investment Management history | 47.76K | $626.07K | 0.00% | Hold |
| Franklin Resources history | 45.81K | $600.52K | 0.00% | Reduce |
| Wells Fargo & Co history | 38.38K | $503.21K | 0.00% | Add |
| Manulife Financial history | 38.33K | $502.48K | 0.00% | Reduce |
| CPP Investments history | 3.40K | $44.57K | 0.00% | New |
| T. Rowe Price Associates history | 50.68K | $665 | 0.00% | Reduce |
| PNC Financial Services history | 49 | $642 | 0.00% | New |
Q1 2025 — 31 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 6.49M | $142.67M | 0.00% | Hold |
| Janus Henderson Group history | 5.28M | $122.85M | 0.07% | Add |
| Vanguard Group history | 4.29M | $94.48M | 0.00% | Reduce |
| Geode Capital Management history | 1.66M | $36.43M | 0.00% | Add |
| Bank of America Corp history | 695.43K | $15.30M | 0.00% | Add |
| Millennium Management history | 681.32K | $14.99M | 0.01% | Reduce |
| Northern Trust Corp history | 606.69K | $13.35M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 521.26K | $11.47M | 0.00% | Reduce |
| Viking Global Investors history | 490.04K | $10.78M | 0.03% | Reduce |
| Morgan Stanley history | 409.00K | $9.00M | 0.00% | Reduce |
| Deutsche Bank AG history | 376.06K | $8.27M | 0.00% | Add |
| Goldman Sachs Group history | 366.64K | $8.07M | 0.00% | Add |
| UBS Group AG history | 243.90K | $5.37M | 0.00% | Add |
| BNY Mellon history | 210.74K | $4.64M | 0.00% | Hold |
| Amundi US history | 308.63K | $4.19M | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 186.02K | $4.09M | 0.00% | Reduce |
| Citadel Advisors history | 181.18K | $3.99M | 0.00% | Reduce |
| D. E. Shaw & Co history | 140.55K | $3.09M | 0.00% | Reduce |
| Balyasny Asset Management history | 120.91K | $2.66M | 0.00% | Add |
| Wellington Management Group history | 113.30K | $2.49M | 0.00% | Reduce |
| Citigroup Inc history | 74.31K | $1.63M | 0.00% | Reduce |
| Manulife Financial history | 56.99K | $1.25M | 0.00% | Add |
| Legal & General Investment Management America history | 50.35K | $1.11M | 0.00% | Hold |
| Point72 Asset Management history | 50.00K | $1.10M | 0.00% | Reduce |
| Invesco Ltd history | 48.13K | $1.06M | 0.00% | Add |
| Franklin Resources history | 46.29K | $1.02M | 0.00% | Add |
| JPMorgan Chase & Co history | 41.10K | $904.20K | 0.00% | Reduce |
| Wells Fargo & Co history | 35.16K | $773.48K | 0.00% | Add |
| Two Sigma Investments history | 35.00K | $769.98K | 0.00% | Reduce |
| AQR Capital Management history | 9.42K | $207.22K | 0.00% | Add |
| T. Rowe Price Associates history | 294.88K | $6.49K | 0.00% | Add |
New Positions (Q2 2026)
- JPMorgan Chase & Co 203.15K sh · $8.48M
- Principal Global Investors 5.47K sh · $222.25K
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 5.92M sh · $186.29M
- Millennium Management sold 342.87K sh · $10.80M
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | 6.61M | 6.47M | 6.63M | 6.35M | 6.78M | 6.49M | 6.48M | 6.39M | — | — | — | — | — | — | — | — | — | — | — | — |
| Fidelity Management & Research (FMR) | 5.49M | 1.02M | 692.96K | 253.32K | 470.72K | 186.02K | 248.04K | 653.21K | 4.78M | 6.37M | 6.49M | 6.40M | 7.36M | 7.94M | 8.59M | 7.98M | 2.82M | 2.52M | 2.50M | 3.15M |
| Geode Capital Management | 2.17M | 1.79M | 1.75M | 1.72M | 1.80M | 1.66M | 1.60M | 1.60M | 1.67M | 1.37M | 947.05K | 891.77K | 856.21K | 775.49K | 722.14K | 523.52K | 396.83K | 438.14K | 391.58K | 242.92K |
| Morgan Stanley | 1.95M | 2.25M | 2.91M | 869.68K | 727.71K | 409.00K | 436.43K | 418.13K | 249.97K | 374.72K | 225.18K | 73.07K | 100.39K | 64.27K | 60.30K | 104.74K | 46.96K | 21.98K | 17.18K | 866 |
| Bank of America Corp | 1.56M | 1.33M | 1.47M | 321.13K | 254.43K | 695.43K | 48.91K | 308.05K | 272.79K | 53.76K | 62.27K | 41.23K | 52.30K | 54.57K | 52.58K | 13.23K | 39.92K | 27.55K | 28.79K | 2.74K |
| Northern Trust Corp | 671.27K | 576.56K | 559.65K | 587.88K | 602.90K | 606.69K | 611.31K | 575.88K | 508.69K | 499.52K | 363.24K | 344.92K | 339.46K | 306.08K | 316.83K | 238.90K | 217.27K | 293.95K | 302.19K | 115.57K |
| Charles Schwab Investment Management | 620.53K | 596.31K | 611.38K | 597.60K | 579.10K | 521.26K | 537.36K | 522.09K | 571.20K | 497.16K | 331.06K | 330.86K | 310.87K | 294.31K | 296.88K | 202.77K | 115.25K | 145.31K | 140.40K | 84.11K |
| Goldman Sachs Group | 599.47K | 629.82K | 788.17K | 527.83K | 631.74K | 366.64K | 346.89K | 482.23K | 1.62M | 1.75M | 881.90K | 947.79K | 1.75M | 754.14K | 1.07M | 62.60K | 145.81K | 132.17K | 40.51K | — |
| Citadel Advisors | 530.81K | 483.73K | 223.30K | 87.62K | 398.75K | 181.18K | 598.65K | 671.05K | 2.37M | 2.75M | 2.60M | 2.77M | 2.68M | 2.78M | 2.85M | 2.76M | 2.54M | 2.64M | 2.46M | 2.43M |
| Norges Bank Investment Management | 510.14K | — | 751.36K | — | 47.76K | — | 47.76K | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Prudential Financial | 260.73K | 10.61K | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Deutsche Bank AG | 245.00K | 221.87K | 214.77K | 154.90K | 147.53K | 376.06K | 275.84K | 217.88K | 31.11K | 25.27K | 20.41K | 21.10K | 17.92K | 23.60K | 16.64K | 12.06K | 14.05K | 22.00K | 24.49K | 7.37K |
| BNY Mellon | 212.35K | 192.43K | 198.61K | 204.24K | 212.86K | 210.74K | 211.06K | 210.77K | 268.71K | 212.26K | 146.17K | 146.28K | 148.92K | 123.88K | 127.69K | 95.86K | 189.24K | 212.89K | 214.51K | 35.41K |
| JPMorgan Chase & Co | 203.15K | — | 146.04K | 68.72K | 77.62K | 41.10K | 124.44K | 158.51K | 64.36K | 42.83K | 40.06K | 40.50K | 35.58K | 2.34K | 24.32K | 19.80K | 21.11K | 27.17K | 22.01K | 7.48K |
| D. E. Shaw & Co | 189.12K | 104.86K | 394.69K | 677.56K | 595.43K | 140.55K | 686.37K | 455.35K | 311.48K | 473.68K | 31.95K | — | — | 24.74K | 11.27K | — | — | — | — | 13.70K |
| UBS Group AG | 174.97K | 1.31M | 2.12M | 114.13K | 170.98K | 243.90K | 92.07K | 75.31K | 60.51K | 74.12K | — | — | — | — | 1.55K | — | — | 22.05K | — | — |
| Point72 Asset Management | 131.86K | 14.60K | — | — | — | 50.00K | 106.56K | — | — | — | 501.26K | — | 107.10K | — | — | — | — | — | — | — |
| Invesco Ltd | 120.93K | 138.40K | 75.44K | 66.06K | 56.16K | 48.13K | 43.44K | 64.78K | 22.24K | 21.15K | 16.53K | 22.98K | 11.72K | 11.86K | 12.87K | 11.90K | 11.96K | 16.91K | 16.52K | — |
| Wells Fargo & Co | 78.90K | 25.24K | 75.44K | 42.20K | 38.38K | 35.16K | 33.92K | 22.36K | 23.24K | 20.43K | 13.18K | 10.57K | 16.28K | 6.76K | — | 59 | 256 | 3.93K | 17.85K | — |
| Citigroup Inc | 59.56K | 18.52K | 223.29K | 538.45K | 724.90K | 74.31K | 78.50K | 75.84K | 23.05K | 36.94K | 7.26K | 1.18K | 14.29K | 719 | 923 | 1.06K | 3.01K | 2.45K | 11.34K | 1.50K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details