CSTL — CASTLE BIOSCIENCES INC
As of Q2 2026, 30 SEC-registered investment managers reported holding CSTL (CASTLE BIOSCIENCES INC) in their latest 13F filings, with a combined reported value of $225.73M across 9.52M shares. That is +6.7% by share count (+595.86K shares) versus the previous quarter, while reported value moved +3.5%. Ownership is concentrated: the five largest holders account for 69.1% of reported value and the top ten for 84.9%.
Compared with the prior quarter, 3 opened new positions, 18 added to existing stakes, 9 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.
CSTL is classified in the Health Care sector.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2026 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 3.29M | $78.51M | 0.00% | Add |
| Principal Global Investors history | 1.73M | $41.18M | 0.02% | Reduce |
| Geode Capital Management history | 795.91K | $18.99M | 0.00% | Add |
| Renaissance Technologies history | 371.20K | $8.85M | 0.01% | Reduce |
| Goldman Sachs Group history | 358.40K | $8.55M | 0.00% | Add |
| Point72 Asset Management history | 357.32K | $8.52M | 0.01% | New |
| Morgan Stanley history | 329.68K | $7.86M | 0.00% | Reduce |
| Northern Trust Corp history | 285.16K | $6.80M | 0.00% | Add |
| Citadel Advisors history | 265.35K | $6.33M | 0.00% | Add |
| Charles Schwab Investment Management history | 254.53K | $6.07M | 0.00% | Add |
| Millennium Management history | 205.37K | $4.90M | 0.00% | Reduce |
| AQR Capital Management history | 166.57K | $3.97M | 0.00% | Add |
| D. E. Shaw & Co history | 112.79K | $2.69M | 0.00% | Reduce |
| Two Sigma Investments history | 100.37K | $2.39M | 0.00% | Reduce |
| Bank of America Corp history | 98.75K | $2.36M | 0.00% | Add |
| BNY Mellon history | 98.02K | $2.34M | 0.00% | Add |
| Franklin Resources history | 97.73K | $2.33M | 0.00% | Add |
| Arrowstreet Capital history | 92.74K | $2.21M | 0.00% | Add |
| UBS Group AG history | 89.37K | $2.13M | 0.00% | Add |
| JPMorgan Chase & Co history | 84.80K | $2.06M | 0.00% | New |
| Norges Bank Investment Management history | 60.10K | $1.43M | 0.00% | New |
| Fidelity Management & Research (FMR) history | 55.87K | $1.33M | 0.00% | Add |
| Invesco Ltd history | 54.89K | $1.31M | 0.00% | Reduce |
| Deutsche Bank AG history | 30.14K | $718.82K | 0.00% | Add |
| Wells Fargo & Co history | 29.54K | $704.60K | 0.00% | Add |
| Legal & General Investment Management America history | 20.55K | $490.07K | 0.00% | Reduce |
| Citigroup Inc history | 16.14K | $385.04K | 0.00% | Add |
| Manulife Financial history | 12.54K | $299.15K | 0.00% | Add |
| PNC Financial Services history | 157 | $3.74K | 0.00% | Reduce |
| T. Rowe Price Associates history | 53.24K | $1.27K | 0.00% | Add |
Q1 2026 — 29 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 2.98M | $73.23M | 0.00% | Reduce |
| Principal Global Investors history | 1.77M | $43.45M | 0.02% | Reduce |
| Geode Capital Management history | 728.10K | $17.88M | 0.00% | Add |
| Renaissance Technologies history | 532.80K | $13.08M | 0.02% | Add |
| Morgan Stanley history | 428.93K | $10.53M | 0.00% | Add |
| Millennium Management history | 353.32K | $8.67M | 0.00% | Add |
| Goldman Sachs Group history | 341.17K | $8.38M | 0.00% | Add |
| Northern Trust Corp history | 273.10K | $6.70M | 0.00% | Add |
| Two Sigma Investments history | 248.84K | $6.11M | 0.01% | Add |
| Charles Schwab Investment Management history | 241.88K | $5.94M | 0.00% | Hold |
| D. E. Shaw & Co history | 211.97K | $5.20M | 0.00% | Add |
| Citadel Advisors history | 165.98K | $4.07M | 0.00% | Reduce |
| Franklin Resources history | 90.91K | $2.23M | 0.00% | Add |
| BNY Mellon history | 88.65K | $2.18M | 0.00% | Add |
| Bank of America Corp history | 67.81K | $1.66M | 0.00% | Reduce |
| AQR Capital Management history | 64.88K | $1.59M | 0.00% | Add |
| Invesco Ltd history | 61.01K | $1.50M | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 50.41K | $1.24M | 0.00% | Add |
| UBS Group AG history | 49.16K | $1.21M | 0.00% | Reduce |
| Arrowstreet Capital history | 27.14K | $666.34K | 0.00% | Add |
| Deutsche Bank AG history | 24.16K | $593.23K | 0.00% | Add |
| Legal & General Investment Management America history | 23.18K | $569.17K | 0.00% | Reduce |
| Janus Henderson Group history | 15.04K | $369.08K | 0.00% | Hold |
| Wells Fargo & Co history | 12.89K | $316.50K | 0.00% | Reduce |
| Manulife Financial history | 12.44K | $305.35K | 0.00% | Add |
| CPP Investments history | 11.40K | $279.87K | 0.00% | Add |
| Citigroup Inc history | 4.03K | $98.86K | 0.00% | Reduce |
| PNC Financial Services history | 163 | $4.00K | 0.00% | Reduce |
| T. Rowe Price Associates history | 37.79K | $928 | 0.00% | Add |
Q4 2025 — 33 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 3.11M | $120.79M | 0.00% | Reduce |
| Vanguard Group history | 2.20M | $85.57M | 0.00% | Add |
| Principal Global Investors history | 1.81M | $70.32M | 0.04% | Add |
| Geode Capital Management history | 714.91K | $27.81M | 0.00% | Add |
| Renaissance Technologies history | 493.10K | $19.18M | 0.03% | Reduce |
| Citadel Advisors history | 406.96K | $15.83M | 0.00% | Add |
| Millennium Management history | 308.91K | $12.02M | 0.01% | Reduce |
| Goldman Sachs Group history | 287.24K | $11.17M | 0.00% | Reduce |
| Bank of America Corp history | 263.02K | $10.23M | 0.00% | Reduce |
| Northern Trust Corp history | 262.24K | $10.20M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 242.53K | $9.43M | 0.00% | Add |
| Wellington Management Group history | 218.56K | $8.50M | 0.00% | New |
| Morgan Stanley history | 203.58K | $7.92M | 0.00% | Reduce |
| D. E. Shaw & Co history | 159.71K | $6.21M | 0.00% | Add |
| UBS Group AG history | 141.87K | $5.52M | 0.00% | Reduce |
| Invesco Ltd history | 135.46K | $5.27M | 0.00% | Add |
| Point72 Asset Management history | 119.46K | $4.65M | 0.01% | Reduce |
| JPMorgan Chase & Co history | 90.03K | $3.50M | 0.00% | Add |
| BNY Mellon history | 86.98K | $3.38M | 0.00% | Reduce |
| Two Sigma Investments history | 84.07K | $3.27M | 0.01% | Add |
| Franklin Resources history | 80.60K | $3.14M | 0.00% | Reduce |
| AQR Capital Management history | 63.88K | $2.48M | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 42.29K | $1.64M | 0.00% | Add |
| Wells Fargo & Co history | 34.21K | $1.33M | 0.00% | Add |
| Citigroup Inc history | 32.42K | $1.26M | 0.00% | Add |
| Legal & General Investment Management America history | 29.73K | $1.16M | 0.00% | Reduce |
| Deutsche Bank AG history | 22.38K | $870.74K | 0.00% | Add |
| Janus Henderson Group history | 15.04K | $585.01K | 0.00% | Add |
| Manulife Financial history | 8.49K | $330.14K | 0.00% | Reduce |
| Arrowstreet Capital history | 7.03K | $273.43K | 0.00% | New |
| CPP Investments history | 6.30K | $245.07K | 0.00% | Add |
| PNC Financial Services history | 546 | $21.24K | 0.00% | Add |
| T. Rowe Price Associates history | 34.14K | $1.33K | 0.00% | Add |
Q3 2025 — 31 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 3.19M | $72.63M | 0.00% | Add |
| Vanguard Group history | 2.17M | $49.46M | 0.00% | Hold |
| Principal Global Investors history | 1.79M | $40.86M | 0.02% | Hold |
| Geode Capital Management history | 698.61K | $15.91M | 0.00% | Add |
| Millennium Management history | 575.09K | $13.09M | 0.01% | Add |
| Renaissance Technologies history | 562.60K | $12.81M | 0.02% | Reduce |
| Goldman Sachs Group history | 345.10K | $7.86M | 0.00% | Add |
| Point72 Asset Management history | 336.96K | $7.67M | 0.01% | New |
| Bank of America Corp history | 315.37K | $7.18M | 0.00% | Reduce |
| UBS Group AG history | 291.36K | $6.63M | 0.00% | Reduce |
| Citadel Advisors history | 284.51K | $6.48M | 0.00% | Reduce |
| Northern Trust Corp history | 282.27K | $6.43M | 0.00% | Add |
| Morgan Stanley history | 269.63K | $6.14M | 0.00% | Add |
| Charles Schwab Investment Management history | 238.15K | $5.42M | 0.00% | Add |
| Franklin Resources history | 99.79K | $2.27M | 0.00% | Add |
| BNY Mellon history | 94.02K | $2.14M | 0.00% | Add |
| D. E. Shaw & Co history | 92.61K | $2.11M | 0.00% | Reduce |
| Invesco Ltd history | 55.84K | $1.27M | 0.00% | Add |
| AQR Capital Management history | 50.84K | $1.16M | 0.00% | Add |
| Legal & General Investment Management America history | 34.91K | $794.85K | 0.00% | Hold |
| Fidelity Management & Research (FMR) history | 28.54K | $649.90K | 0.00% | Add |
| JPMorgan Chase & Co history | 27.78K | $632.50K | 0.00% | Add |
| Two Sigma Investments history | 25.70K | $585.19K | 0.00% | Reduce |
| Wells Fargo & Co history | 23.98K | $546.00K | 0.00% | Add |
| Deutsche Bank AG history | 16.64K | $378.94K | 0.00% | Reduce |
| Manulife Financial history | 9.54K | $217.20K | 0.00% | Reduce |
| Janus Henderson Group history | 9.14K | $208.23K | 0.00% | New |
| Citigroup Inc history | 4.25K | $96.77K | 0.00% | Reduce |
| CPP Investments history | 2.40K | $54.65K | 0.00% | New |
| PNC Financial Services history | 115 | $2.62K | 0.00% | Add |
| T. Rowe Price Associates history | 32.59K | $743 | 0.00% | Add |
Q2 2025 — 30 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 3.15M | $64.42M | 0.00% | Add |
| Vanguard Group history | 2.17M | $44.31M | 0.00% | Add |
| Principal Global Investors history | 1.80M | $36.74M | 0.02% | Add |
| Citadel Advisors history | 888.51K | $18.14M | 0.00% | Add |
| Geode Capital Management history | 689.93K | $14.09M | 0.00% | Add |
| Renaissance Technologies history | 670.50K | $13.69M | 0.02% | Reduce |
| Millennium Management history | 428.40K | $8.75M | 0.00% | Add |
| Wellington Management Group history | 407.21K | $8.32M | 0.00% | Reduce |
| Bank of America Corp history | 382.75K | $7.82M | 0.00% | Add |
| UBS Group AG history | 363.85K | $7.43M | 0.00% | Add |
| Northern Trust Corp history | 279.82K | $5.71M | 0.00% | Add |
| Goldman Sachs Group history | 273.44K | $5.58M | 0.00% | Add |
| Charles Schwab Investment Management history | 235.01K | $4.80M | 0.00% | Reduce |
| Morgan Stanley history | 167.59K | $3.42M | 0.00% | Reduce |
| D. E. Shaw & Co history | 148.19K | $3.03M | 0.00% | Reduce |
| Franklin Resources history | 99.25K | $2.03M | 0.00% | Hold |
| BNY Mellon history | 89.88K | $1.84M | 0.00% | Add |
| Deutsche Bank AG history | 61.74K | $1.26M | 0.00% | Reduce |
| AQR Capital Management history | 49.23K | $1.01M | 0.00% | Reduce |
| Invesco Ltd history | 40.43K | $825.56K | 0.00% | Add |
| Legal & General Investment Management America history | 34.91K | $712.82K | 0.00% | Add |
| Two Sigma Investments history | 28.24K | $576.68K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 26.66K | $544.46K | 0.00% | Reduce |
| Fidelity Management & Research (FMR) history | 24.00K | $490.08K | 0.00% | Add |
| Wells Fargo & Co history | 20.30K | $414.53K | 0.00% | Add |
| Citigroup Inc history | 14.07K | $287.35K | 0.00% | Reduce |
| Manulife Financial history | 10.32K | $210.65K | 0.00% | New |
| PNC Financial Services history | 110 | $2.25K | 0.00% | Reduce |
| T. Rowe Price Associates history | 26.41K | $540 | 0.00% | Add |
| Lazard Asset Management history | 72 | $1 | 0.00% | Reduce |
Q1 2025 — 33 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| BlackRock Inc history | 2.98M | $59.73M | 0.00% | Add |
| Vanguard Group history | 2.05M | $40.99M | 0.00% | Add |
| Principal Global Investors history | 1.47M | $29.39M | 0.02% | Add |
| Wellington Management Group history | 828.53K | $16.59M | 0.00% | Add |
| Renaissance Technologies history | 701.20K | $14.04M | 0.02% | Add |
| Geode Capital Management history | 649.85K | $13.01M | 0.00% | Add |
| Bank of America Corp history | 375.38K | $7.52M | 0.00% | Reduce |
| Northern Trust Corp history | 273.47K | $5.47M | 0.00% | Reduce |
| Citadel Advisors history | 272.88K | $5.46M | 0.00% | Reduce |
| Millennium Management history | 254.75K | $5.10M | 0.00% | Reduce |
| Charles Schwab Investment Management history | 242.26K | $4.85M | 0.00% | Reduce |
| Point72 Asset Management history | 236.22K | $4.73M | 0.01% | Reduce |
| Morgan Stanley history | 211.79K | $4.24M | 0.00% | Reduce |
| D. E. Shaw & Co history | 189.18K | $3.79M | 0.00% | Add |
| Goldman Sachs Group history | 175.32K | $3.51M | 0.00% | Reduce |
| Two Sigma Investments history | 139.78K | $2.80M | 0.01% | New |
| AQR Capital Management history | 137.02K | $2.74M | 0.00% | Add |
| Franklin Resources history | 99.09K | $1.98M | 0.00% | Add |
| BNY Mellon history | 84.04K | $1.68M | 0.00% | Hold |
| Deutsche Bank AG history | 65.54K | $1.31M | 0.00% | Reduce |
| Citigroup Inc history | 62.70K | $1.26M | 0.00% | Add |
| UBS Group AG history | 48.76K | $976.15K | 0.00% | Reduce |
| Invesco Ltd history | 32.25K | $645.66K | 0.00% | Add |
| JPMorgan Chase & Co history | 30.58K | $612.15K | 0.00% | Reduce |
| Legal & General Investment Management America history | 25.92K | $518.84K | 0.00% | Hold |
| Balyasny Asset Management history | 19.73K | $395.00K | 0.00% | New |
| Wells Fargo & Co history | 16.35K | $327.27K | 0.00% | Add |
| Amundi US history | 4.14K | $79.39K | 0.00% | Add |
| CPP Investments history | 2.40K | $48.05K | 0.00% | Add |
| Fidelity Management & Research (FMR) history | 1.16K | $23.14K | 0.00% | Add |
| PNC Financial Services history | 120 | $2.40K | 0.00% | New |
| T. Rowe Price Associates history | 23.70K | $475 | 0.00% | Add |
| Lazard Asset Management history | 4.93K | $98 | 0.00% | New |
New Positions (Q2 2026)
- Point72 Asset Management 357.32K sh · $8.52M
- JPMorgan Chase & Co 84.80K sh · $2.06M
- Norges Bank Investment Management 60.10K sh · $1.43M
Fully Exited (vs previous quarter)
- Janus Henderson Group sold 15.04K sh · $369.08K
- CPP Investments sold 11.40K sh · $279.87K
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlackRock Inc | 3.29M | 2.98M | 3.11M | 3.19M | 3.15M | 2.98M | 2.92M | 3.12M | — | — | — | — | — | — | — | — | — | — | — | — |
| Principal Global Investors | 1.73M | 1.77M | 1.81M | 1.79M | 1.80M | 1.47M | 1.44M | 1.54M | 1.50M | 1.53M | 1.59M | 1.48M | 1.36M | 1.29M | 910.82K | 435.74K | 249.68K | 177.45K | 182.67K | 169.82K |
| Geode Capital Management | 795.91K | 728.10K | 714.91K | 698.61K | 689.93K | 649.85K | 628.20K | 624.68K | 617.68K | 578.53K | 566.12K | 536.24K | 497.68K | 484.95K | 465.67K | 445.66K | 430.56K | 401.01K | 385.74K | 365.37K |
| Renaissance Technologies | 371.20K | 532.80K | 493.10K | 562.60K | 670.50K | 701.20K | 685.00K | 489.56K | 301.50K | 204.70K | 112.40K | 106.80K | 172.40K | 36.40K | 22.10K | 17.00K | 17.40K | 25.00K | 134.28K | — |
| Goldman Sachs Group | 358.40K | 341.17K | 287.24K | 345.10K | 273.44K | 175.32K | 432.75K | 242.80K | 217.14K | 124.67K | 80.39K | 151.75K | 81.72K | 137.91K | 246.86K | 182.67K | 119.69K | 63.22K | 71.41K | 227.51K |
| Point72 Asset Management | 357.32K | — | 119.46K | 336.96K | — | 236.22K | 547.10K | 499.19K | 53.78K | — | — | 44.20K | — | 284.85K | 201.38K | — | — | 623.29K | 482.85K | 103.18K |
| Morgan Stanley | 329.68K | 428.93K | 203.58K | 269.63K | 167.59K | 211.79K | 306.68K | 396.92K | 249.38K | 650.71K | 478.04K | 38.65K | 104.78K | 88.86K | 58.32K | 195.80K | 108.94K | 27.14K | 42.90K | 69.82K |
| Northern Trust Corp | 285.16K | 273.10K | 262.24K | 282.27K | 279.82K | 273.47K | 284.59K | 261.93K | 238.49K | 244.39K | 249.98K | 243.85K | 237.08K | 225.70K | 230.09K | 227.47K | 222.13K | 212.32K | 218.66K | 223.59K |
| Citadel Advisors | 265.35K | 165.98K | 406.96K | 284.51K | 888.51K | 272.88K | 884.01K | 694.92K | 705.88K | 692.07K | 338.85K | 574.46K | 65.28K | 673.96K | 580.62K | 761.75K | 630.60K | 187.01K | 97.89K | 248.04K |
| Charles Schwab Investment Management | 254.53K | 241.88K | 242.53K | 238.15K | 235.01K | 242.26K | 258.87K | 274.76K | 235.34K | 204.94K | 207.29K | 200.99K | 186.00K | 183.67K | 184.54K | 177.63K | 171.04K | 166.11K | 161.91K | 158.42K |
| Millennium Management | 205.37K | 353.32K | 308.91K | 575.09K | 428.40K | 254.75K | 548.81K | 140.54K | 494.83K | 248.55K | 716.35K | 595.10K | 1.05M | 825.44K | 913.38K | 1.01M | 902.09K | 272.64K | 516.51K | 403.36K |
| AQR Capital Management | 166.57K | 64.88K | 63.88K | 50.84K | 49.23K | 137.02K | 21.11K | — | — | 22.80K | 14.20K | 14.44K | — | — | — | — | — | — | — | — |
| D. E. Shaw & Co | 112.79K | 211.97K | 159.71K | 92.61K | 148.19K | 189.18K | 90.56K | — | — | 13.38K | 52.36K | — | — | — | 28.94K | 27.53K | — | — | — | 7.10K |
| Two Sigma Investments | 100.37K | 248.84K | 84.07K | 25.70K | 28.24K | 139.78K | — | 9.80K | 16.80K | 16.70K | 17.30K | 12.80K | 31.90K | 22.62K | 53.95K | 121.55K | 149.43K | — | 135.37K | 72.97K |
| Bank of America Corp | 98.75K | 67.81K | 263.02K | 315.37K | 382.75K | 375.38K | 403.55K | 201.75K | 79.61K | 151.16K | 138.58K | 42.72K | 44.64K | 57.16K | 48.96K | 125.07K | 45.92K | 37.01K | 38.80K | 20.97K |
| BNY Mellon | 98.02K | 88.65K | 86.98K | 94.02K | 89.88K | 84.04K | 84.46K | 76.58K | 96.69K | 84.11K | 93.31K | 81.14K | 80.08K | 81.37K | 82.98K | 81.02K | 71.24K | 101.89K | 87.23K | 88.50K |
| Franklin Resources | 97.73K | 90.91K | 80.60K | 99.79K | 99.25K | 99.09K | 73.64K | 69.38K | 37.04K | 35.50K | — | — | — | — | — | — | — | — | — | — |
| Arrowstreet Capital | 92.74K | 27.14K | 7.03K | — | — | — | 28.90K | — | — | — | — | — | — | — | — | — | — | — | — | — |
| UBS Group AG | 89.37K | 49.16K | 141.87K | 291.36K | 363.85K | 48.76K | 839.00K | 80.53K | 48.72K | 54.84K | 41.48K | 18.04K | 17.30K | 10.57K | 10.48K | 7.13K | 16.23K | 3.85K | 10.40K | 1.26K |
| JPMorgan Chase & Co | 84.80K | — | 90.03K | 27.78K | 26.66K | 30.58K | 107.94K | 69.41K | 26.17K | 76.14K | 50.37K | 52.66K | 51.50K | 13.40K | 35.40K | 32.95K | 30.12K | 24.32K | 23.57K | 28.49K |
▲ Bought Low (fund opened/added, stock rose ≥5% next quarter) ▼ Sold High (fund reduced, stock fell ≥5% next quarter)
Drag / scroll to zoom · Default shows the most recent year · Annotations come from quarterly fund actions in 13F filings · Hover a marker for details