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CSTL — CASTLE BIOSCIENCES INC

Reported value held$380.94M
Funds holding (latest)43
SectorHealth Care
Funds holding (Q2 2026)30
Institutional value$225.73M · 9.52M sh
New / Add / Cut / Exit3 / 18 / 9 / 2
Top-5 / Top-10 concentration69.1% / 84.9%
Institutional holdings change Accumulating +6.7% (+595.86K sh)
Institutional value change Up +3.5%

As of Q2 2026, 30 SEC-registered investment managers reported holding CSTL (CASTLE BIOSCIENCES INC) in their latest 13F filings, with a combined reported value of $225.73M across 9.52M shares. That is +6.7% by share count (+595.86K shares) versus the previous quarter, while reported value moved +3.5%. Ownership is concentrated: the five largest holders account for 69.1% of reported value and the top ten for 84.9%.

Compared with the prior quarter, 3 opened new positions, 18 added to existing stakes, 9 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

CSTL is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

Q2 2026 — 30 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.29M $78.51M 0.00% Add
Principal Global Investors history 1.73M $41.18M 0.02% Reduce
Geode Capital Management history 795.91K $18.99M 0.00% Add
Renaissance Technologies history 371.20K $8.85M 0.01% Reduce
Goldman Sachs Group history 358.40K $8.55M 0.00% Add
Point72 Asset Management history 357.32K $8.52M 0.01% New
Morgan Stanley history 329.68K $7.86M 0.00% Reduce
Northern Trust Corp history 285.16K $6.80M 0.00% Add
Citadel Advisors history 265.35K $6.33M 0.00% Add
Charles Schwab Investment Management history 254.53K $6.07M 0.00% Add
Millennium Management history 205.37K $4.90M 0.00% Reduce
AQR Capital Management history 166.57K $3.97M 0.00% Add
D. E. Shaw & Co history 112.79K $2.69M 0.00% Reduce
Two Sigma Investments history 100.37K $2.39M 0.00% Reduce
Bank of America Corp history 98.75K $2.36M 0.00% Add
BNY Mellon history 98.02K $2.34M 0.00% Add
Franklin Resources history 97.73K $2.33M 0.00% Add
Arrowstreet Capital history 92.74K $2.21M 0.00% Add
UBS Group AG history 89.37K $2.13M 0.00% Add
JPMorgan Chase & Co history 84.80K $2.06M 0.00% New
Norges Bank Investment Management history 60.10K $1.43M 0.00% New
Fidelity Management & Research (FMR) history 55.87K $1.33M 0.00% Add
Invesco Ltd history 54.89K $1.31M 0.00% Reduce
Deutsche Bank AG history 30.14K $718.82K 0.00% Add
Wells Fargo & Co history 29.54K $704.60K 0.00% Add
Legal & General Investment Management America history 20.55K $490.07K 0.00% Reduce
Citigroup Inc history 16.14K $385.04K 0.00% Add
Manulife Financial history 12.54K $299.15K 0.00% Add
PNC Financial Services history 157 $3.74K 0.00% Reduce
T. Rowe Price Associates history 53.24K $1.27K 0.00% Add

Q1 2026 — 29 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 2.98M $73.23M 0.00% Reduce
Principal Global Investors history 1.77M $43.45M 0.02% Reduce
Geode Capital Management history 728.10K $17.88M 0.00% Add
Renaissance Technologies history 532.80K $13.08M 0.02% Add
Morgan Stanley history 428.93K $10.53M 0.00% Add
Millennium Management history 353.32K $8.67M 0.00% Add
Goldman Sachs Group history 341.17K $8.38M 0.00% Add
Northern Trust Corp history 273.10K $6.70M 0.00% Add
Two Sigma Investments history 248.84K $6.11M 0.01% Add
Charles Schwab Investment Management history 241.88K $5.94M 0.00% Hold
D. E. Shaw & Co history 211.97K $5.20M 0.00% Add
Citadel Advisors history 165.98K $4.07M 0.00% Reduce
Franklin Resources history 90.91K $2.23M 0.00% Add
BNY Mellon history 88.65K $2.18M 0.00% Add
Bank of America Corp history 67.81K $1.66M 0.00% Reduce
AQR Capital Management history 64.88K $1.59M 0.00% Add
Invesco Ltd history 61.01K $1.50M 0.00% Reduce
Fidelity Management & Research (FMR) history 50.41K $1.24M 0.00% Add
UBS Group AG history 49.16K $1.21M 0.00% Reduce
Arrowstreet Capital history 27.14K $666.34K 0.00% Add
Deutsche Bank AG history 24.16K $593.23K 0.00% Add
Legal & General Investment Management America history 23.18K $569.17K 0.00% Reduce
Janus Henderson Group history 15.04K $369.08K 0.00% Hold
Wells Fargo & Co history 12.89K $316.50K 0.00% Reduce
Manulife Financial history 12.44K $305.35K 0.00% Add
CPP Investments history 11.40K $279.87K 0.00% Add
Citigroup Inc history 4.03K $98.86K 0.00% Reduce
PNC Financial Services history 163 $4.00K 0.00% Reduce
T. Rowe Price Associates history 37.79K $928 0.00% Add

Q4 2025 — 33 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.11M $120.79M 0.00% Reduce
Vanguard Group history 2.20M $85.57M 0.00% Add
Principal Global Investors history 1.81M $70.32M 0.04% Add
Geode Capital Management history 714.91K $27.81M 0.00% Add
Renaissance Technologies history 493.10K $19.18M 0.03% Reduce
Citadel Advisors history 406.96K $15.83M 0.00% Add
Millennium Management history 308.91K $12.02M 0.01% Reduce
Goldman Sachs Group history 287.24K $11.17M 0.00% Reduce
Bank of America Corp history 263.02K $10.23M 0.00% Reduce
Northern Trust Corp history 262.24K $10.20M 0.00% Reduce
Charles Schwab Investment Management history 242.53K $9.43M 0.00% Add
Wellington Management Group history 218.56K $8.50M 0.00% New
Morgan Stanley history 203.58K $7.92M 0.00% Reduce
D. E. Shaw & Co history 159.71K $6.21M 0.00% Add
UBS Group AG history 141.87K $5.52M 0.00% Reduce
Invesco Ltd history 135.46K $5.27M 0.00% Add
Point72 Asset Management history 119.46K $4.65M 0.01% Reduce
JPMorgan Chase & Co history 90.03K $3.50M 0.00% Add
BNY Mellon history 86.98K $3.38M 0.00% Reduce
Two Sigma Investments history 84.07K $3.27M 0.01% Add
Franklin Resources history 80.60K $3.14M 0.00% Reduce
AQR Capital Management history 63.88K $2.48M 0.00% Add
Fidelity Management & Research (FMR) history 42.29K $1.64M 0.00% Add
Wells Fargo & Co history 34.21K $1.33M 0.00% Add
Citigroup Inc history 32.42K $1.26M 0.00% Add
Legal & General Investment Management America history 29.73K $1.16M 0.00% Reduce
Deutsche Bank AG history 22.38K $870.74K 0.00% Add
Janus Henderson Group history 15.04K $585.01K 0.00% Add
Manulife Financial history 8.49K $330.14K 0.00% Reduce
Arrowstreet Capital history 7.03K $273.43K 0.00% New
CPP Investments history 6.30K $245.07K 0.00% Add
PNC Financial Services history 546 $21.24K 0.00% Add
T. Rowe Price Associates history 34.14K $1.33K 0.00% Add

Q3 2025 — 31 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.19M $72.63M 0.00% Add
Vanguard Group history 2.17M $49.46M 0.00% Hold
Principal Global Investors history 1.79M $40.86M 0.02% Hold
Geode Capital Management history 698.61K $15.91M 0.00% Add
Millennium Management history 575.09K $13.09M 0.01% Add
Renaissance Technologies history 562.60K $12.81M 0.02% Reduce
Goldman Sachs Group history 345.10K $7.86M 0.00% Add
Point72 Asset Management history 336.96K $7.67M 0.01% New
Bank of America Corp history 315.37K $7.18M 0.00% Reduce
UBS Group AG history 291.36K $6.63M 0.00% Reduce
Citadel Advisors history 284.51K $6.48M 0.00% Reduce
Northern Trust Corp history 282.27K $6.43M 0.00% Add
Morgan Stanley history 269.63K $6.14M 0.00% Add
Charles Schwab Investment Management history 238.15K $5.42M 0.00% Add
Franklin Resources history 99.79K $2.27M 0.00% Add
BNY Mellon history 94.02K $2.14M 0.00% Add
D. E. Shaw & Co history 92.61K $2.11M 0.00% Reduce
Invesco Ltd history 55.84K $1.27M 0.00% Add
AQR Capital Management history 50.84K $1.16M 0.00% Add
Legal & General Investment Management America history 34.91K $794.85K 0.00% Hold
Fidelity Management & Research (FMR) history 28.54K $649.90K 0.00% Add
JPMorgan Chase & Co history 27.78K $632.50K 0.00% Add
Two Sigma Investments history 25.70K $585.19K 0.00% Reduce
Wells Fargo & Co history 23.98K $546.00K 0.00% Add
Deutsche Bank AG history 16.64K $378.94K 0.00% Reduce
Manulife Financial history 9.54K $217.20K 0.00% Reduce
Janus Henderson Group history 9.14K $208.23K 0.00% New
Citigroup Inc history 4.25K $96.77K 0.00% Reduce
CPP Investments history 2.40K $54.65K 0.00% New
PNC Financial Services history 115 $2.62K 0.00% Add
T. Rowe Price Associates history 32.59K $743 0.00% Add

Q2 2025 — 30 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 3.15M $64.42M 0.00% Add
Vanguard Group history 2.17M $44.31M 0.00% Add
Principal Global Investors history 1.80M $36.74M 0.02% Add
Citadel Advisors history 888.51K $18.14M 0.00% Add
Geode Capital Management history 689.93K $14.09M 0.00% Add
Renaissance Technologies history 670.50K $13.69M 0.02% Reduce
Millennium Management history 428.40K $8.75M 0.00% Add
Wellington Management Group history 407.21K $8.32M 0.00% Reduce
Bank of America Corp history 382.75K $7.82M 0.00% Add
UBS Group AG history 363.85K $7.43M 0.00% Add
Northern Trust Corp history 279.82K $5.71M 0.00% Add
Goldman Sachs Group history 273.44K $5.58M 0.00% Add
Charles Schwab Investment Management history 235.01K $4.80M 0.00% Reduce
Morgan Stanley history 167.59K $3.42M 0.00% Reduce
D. E. Shaw & Co history 148.19K $3.03M 0.00% Reduce
Franklin Resources history 99.25K $2.03M 0.00% Hold
BNY Mellon history 89.88K $1.84M 0.00% Add
Deutsche Bank AG history 61.74K $1.26M 0.00% Reduce
AQR Capital Management history 49.23K $1.01M 0.00% Reduce
Invesco Ltd history 40.43K $825.56K 0.00% Add
Legal & General Investment Management America history 34.91K $712.82K 0.00% Add
Two Sigma Investments history 28.24K $576.68K 0.00% Reduce
JPMorgan Chase & Co history 26.66K $544.46K 0.00% Reduce
Fidelity Management & Research (FMR) history 24.00K $490.08K 0.00% Add
Wells Fargo & Co history 20.30K $414.53K 0.00% Add
Citigroup Inc history 14.07K $287.35K 0.00% Reduce
Manulife Financial history 10.32K $210.65K 0.00% New
PNC Financial Services history 110 $2.25K 0.00% Reduce
T. Rowe Price Associates history 26.41K $540 0.00% Add
Lazard Asset Management history 72 $1 0.00% Reduce

Q1 2025 — 33 funds

FundSharesValuePortfolio WeightChange
BlackRock Inc history 2.98M $59.73M 0.00% Add
Vanguard Group history 2.05M $40.99M 0.00% Add
Principal Global Investors history 1.47M $29.39M 0.02% Add
Wellington Management Group history 828.53K $16.59M 0.00% Add
Renaissance Technologies history 701.20K $14.04M 0.02% Add
Geode Capital Management history 649.85K $13.01M 0.00% Add
Bank of America Corp history 375.38K $7.52M 0.00% Reduce
Northern Trust Corp history 273.47K $5.47M 0.00% Reduce
Citadel Advisors history 272.88K $5.46M 0.00% Reduce
Millennium Management history 254.75K $5.10M 0.00% Reduce
Charles Schwab Investment Management history 242.26K $4.85M 0.00% Reduce
Point72 Asset Management history 236.22K $4.73M 0.01% Reduce
Morgan Stanley history 211.79K $4.24M 0.00% Reduce
D. E. Shaw & Co history 189.18K $3.79M 0.00% Add
Goldman Sachs Group history 175.32K $3.51M 0.00% Reduce
Two Sigma Investments history 139.78K $2.80M 0.01% New
AQR Capital Management history 137.02K $2.74M 0.00% Add
Franklin Resources history 99.09K $1.98M 0.00% Add
BNY Mellon history 84.04K $1.68M 0.00% Hold
Deutsche Bank AG history 65.54K $1.31M 0.00% Reduce
Citigroup Inc history 62.70K $1.26M 0.00% Add
UBS Group AG history 48.76K $976.15K 0.00% Reduce
Invesco Ltd history 32.25K $645.66K 0.00% Add
JPMorgan Chase & Co history 30.58K $612.15K 0.00% Reduce
Legal & General Investment Management America history 25.92K $518.84K 0.00% Hold
Balyasny Asset Management history 19.73K $395.00K 0.00% New
Wells Fargo & Co history 16.35K $327.27K 0.00% Add
Amundi US history 4.14K $79.39K 0.00% Add
CPP Investments history 2.40K $48.05K 0.00% Add
Fidelity Management & Research (FMR) history 1.16K $23.14K 0.00% Add
PNC Financial Services history 120 $2.40K 0.00% New
T. Rowe Price Associates history 23.70K $475 0.00% Add
Lazard Asset Management history 4.93K $98 0.00% New

View all 43 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021
BlackRock Inc 3.29M 2.98M 3.11M 3.19M 3.15M 2.98M 2.92M 3.12M — — — — — — — — — — — —
Principal Global Investors 1.73M 1.77M 1.81M 1.79M 1.80M 1.47M 1.44M 1.54M 1.50M 1.53M 1.59M 1.48M 1.36M 1.29M 910.82K 435.74K 249.68K 177.45K 182.67K 169.82K
Geode Capital Management 795.91K 728.10K 714.91K 698.61K 689.93K 649.85K 628.20K 624.68K 617.68K 578.53K 566.12K 536.24K 497.68K 484.95K 465.67K 445.66K 430.56K 401.01K 385.74K 365.37K
Renaissance Technologies 371.20K 532.80K 493.10K 562.60K 670.50K 701.20K 685.00K 489.56K 301.50K 204.70K 112.40K 106.80K 172.40K 36.40K 22.10K 17.00K 17.40K 25.00K 134.28K —
Goldman Sachs Group 358.40K 341.17K 287.24K 345.10K 273.44K 175.32K 432.75K 242.80K 217.14K 124.67K 80.39K 151.75K 81.72K 137.91K 246.86K 182.67K 119.69K 63.22K 71.41K 227.51K
Point72 Asset Management 357.32K — 119.46K 336.96K — 236.22K 547.10K 499.19K 53.78K — — 44.20K — 284.85K 201.38K — — 623.29K 482.85K 103.18K
Morgan Stanley 329.68K 428.93K 203.58K 269.63K 167.59K 211.79K 306.68K 396.92K 249.38K 650.71K 478.04K 38.65K 104.78K 88.86K 58.32K 195.80K 108.94K 27.14K 42.90K 69.82K
Northern Trust Corp 285.16K 273.10K 262.24K 282.27K 279.82K 273.47K 284.59K 261.93K 238.49K 244.39K 249.98K 243.85K 237.08K 225.70K 230.09K 227.47K 222.13K 212.32K 218.66K 223.59K
Citadel Advisors 265.35K 165.98K 406.96K 284.51K 888.51K 272.88K 884.01K 694.92K 705.88K 692.07K 338.85K 574.46K 65.28K 673.96K 580.62K 761.75K 630.60K 187.01K 97.89K 248.04K
Charles Schwab Investment Management 254.53K 241.88K 242.53K 238.15K 235.01K 242.26K 258.87K 274.76K 235.34K 204.94K 207.29K 200.99K 186.00K 183.67K 184.54K 177.63K 171.04K 166.11K 161.91K 158.42K
Millennium Management 205.37K 353.32K 308.91K 575.09K 428.40K 254.75K 548.81K 140.54K 494.83K 248.55K 716.35K 595.10K 1.05M 825.44K 913.38K 1.01M 902.09K 272.64K 516.51K 403.36K
AQR Capital Management 166.57K 64.88K 63.88K 50.84K 49.23K 137.02K 21.11K — — 22.80K 14.20K 14.44K — — — — — — — —
D. E. Shaw & Co 112.79K 211.97K 159.71K 92.61K 148.19K 189.18K 90.56K — — 13.38K 52.36K — — — 28.94K 27.53K — — — 7.10K
Two Sigma Investments 100.37K 248.84K 84.07K 25.70K 28.24K 139.78K — 9.80K 16.80K 16.70K 17.30K 12.80K 31.90K 22.62K 53.95K 121.55K 149.43K — 135.37K 72.97K
Bank of America Corp 98.75K 67.81K 263.02K 315.37K 382.75K 375.38K 403.55K 201.75K 79.61K 151.16K 138.58K 42.72K 44.64K 57.16K 48.96K 125.07K 45.92K 37.01K 38.80K 20.97K
BNY Mellon 98.02K 88.65K 86.98K 94.02K 89.88K 84.04K 84.46K 76.58K 96.69K 84.11K 93.31K 81.14K 80.08K 81.37K 82.98K 81.02K 71.24K 101.89K 87.23K 88.50K
Franklin Resources 97.73K 90.91K 80.60K 99.79K 99.25K 99.09K 73.64K 69.38K 37.04K 35.50K — — — — — — — — — —
Arrowstreet Capital 92.74K 27.14K 7.03K — — — 28.90K — — — — — — — — — — — — —
UBS Group AG 89.37K 49.16K 141.87K 291.36K 363.85K 48.76K 839.00K 80.53K 48.72K 54.84K 41.48K 18.04K 17.30K 10.57K 10.48K 7.13K 16.23K 3.85K 10.40K 1.26K
JPMorgan Chase & Co 84.80K — 90.03K 27.78K 26.66K 30.58K 107.94K 69.41K 26.17K 76.14K 50.37K 52.66K 51.50K 13.40K 35.40K 32.95K 30.12K 24.32K 23.57K 28.49K

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