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BCYC — BICYCLE THERAPEUTICS PLC

Reported value held$53.86M
Funds holding (latest)30
SectorHealth Care
Funds holding (Q2 2026)19
Institutional value$24.04M · 6.57M sh
New / Add / Cut / Exit2 / 9 / 4 / 2
Top-5 / Top-10 concentration73.7% / 96.1%
Institutional holdings change Accumulating +8.7% (+528.05K sh)
Institutional value change Up +3.3%

As of Q2 2026, 19 SEC-registered investment managers reported holding BCYC (BICYCLE THERAPEUTICS PLC) in their latest 13F filings, with a combined reported value of $24.04M across 6.57M shares. That is +8.7% by share count (+528.05K shares) versus the previous quarter, while reported value moved +3.3%. Ownership is concentrated: the five largest holders account for 73.7% of reported value and the top ten for 96.1%.

Compared with the prior quarter, 2 opened new positions, 9 added to existing stakes, 4 trimmed, 2 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

BCYC is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

FundQuarterSharesValuePortfolio WeightChange
Janus Henderson Group history Q3 2023 910.93K $18.30M 0.01% Reduce
Renaissance Technologies history Q2 2026 1.53M $6.50M 0.01% Add
Principal Global Investors history Q1 2026 1.17M $5.45M 0.00% Add
Marshall Wace history Q2 2026 797.94K $3.38M 0.00% Add
Morgan Stanley history Q2 2026 667.27K $2.83M 0.00% Add
Citadel Advisors history Q2 2026 627.73K $2.66M 0.00% Add
Hillhouse Capital (HHLR Advisors) history Q2 2024 125.28K $2.54M 0.06% New
Millennium Management history Q2 2026 553.97K $2.35M 0.00% Add
Balyasny Asset Management history Q4 2025 300.00K $2.12M 0.00% New
Two Sigma Investments history Q2 2026 434.58K $1.84M 0.00% Add
BlackRock Inc history Q2 2026 280.39K $1.19M 0.00% Hold
Moore Capital Management history Q2 2026 275.00K $1.17M 0.02% Hold
Bank of America Corp history Q4 2025 96.40K $682.52K 0.00% Reduce
Point72 Asset Management history Q2 2026 149.94K $635.73K 0.00% Add
Manulife Financial history Q2 2026 127.86K $542.14K 0.00% Hold
Goldman Sachs Group history Q2 2026 121.28K $514.23K 0.00% Add
BNY Mellon history Q3 2021 8.49K $353.00K 0.00% New
Northern Trust Corp history Q4 2021 2.90K $177.00K 0.00% New
D. E. Shaw & Co history Q2 2026 25.46K $107.94K 0.00% New
Invesco Ltd history Q2 2026 24.80K $105.16K 0.00% Add

View all 30 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ3 2021Q4 2021Q1 2022Q2 2022Q3 2022Q4 2022Q1 2023Q2 2023Q3 2023Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Renaissance Technologies — 73.18K 64.40K 153.20K — — 61.90K 70.90K 82.00K 105.50K 165.70K 326.80K 272.60K 269.50K 301.50K 318.40K 518.70K 566.60K 979.30K 1.53M
Marshall Wace 7.69K 50.40K 10.62K 80.12K 9.27K 9.27K 76.65K 9.27K — — — 88.99K 330.26K — — — — 38.80K 377.33K 797.94K
Morgan Stanley 144.61K 150.01K 87.92K 821.20K 859.85K 721.56K 1.51M 1.44M 1.62M 1.03M 1.52M 1.23M 1.35M 862.14K 999.84K 1.04M 822.71K 465.22K 618.33K 667.27K
Citadel Advisors 36.25K 83.19K 28.50K 334.93K 48.40K 61.49K 98.30K 141.86K 169.90K 322.76K 77.44K 188.22K 120.45K 154.93K 165.37K 157.17K 189.03K 313.08K 410.69K 627.73K
Millennium Management — 152.73K 163.37K 333.70K 143.05K 168.72K 16.84K 78.76K 315.09K 249.13K — 37.51K — 176.76K 453.43K 1.44M 1.05M 326.63K 283.99K 553.97K
Two Sigma Investments 92.19K 151.36K 177.32K 380.65K 49.50K — 160.58K 52.63K 22.93K 103.63K 28.59K 26.58K — — — 56.20K 184.54K 132.03K 164.80K 434.58K
BlackRock Inc — — — — — — — — — — — — 419.76K 365.41K 322.88K 264.35K 282.42K 332.89K 278.99K 280.39K
Moore Capital Management — — — — — — — — — — — — — — 50.00K 75.00K 125.00K 275.00K 275.00K 275.00K
Point72 Asset Management 1.62M 1.57M 1.62M 1.45M 1.26M 1.01M 802.40K 478.00K 1.30M 225.90K 342.59K 58.50K 899.80K 4.55M 3.69M 1.77M 430.90K 76.78K 130.42K 149.94K
Manulife Financial — — 19.53K 25.14K 25.14K 25.14K 25.14K 25.14K 36.09K 13.17K 25.96K 97.39K 129.71K 124.50K 138.25K 140.49K 140.49K 127.86K 127.86K 127.86K
Goldman Sachs Group 14.86K 20.69K 163.26K 154.33K 105.29K 80.55K 10.55K 18.21K — — 55.45K 13.91K — — 25.19K 52.27K — 24.73K 110.15K 121.28K
D. E. Shaw & Co — — — — — — — — — — — — — — — — — 21.55K — 25.46K
Invesco Ltd — — — — — — — — — — — — — — — — — 10.09K 15.07K 24.80K
Geode Capital Management 9.88K 9.88K 11.13K 11.13K 21.42K 17.14K 17.14K 17.14K 17.14K 18.84K 21.38K 21.38K 38.34K 38.81K 21.38K 40.41K 39.92K 25.13K 25.13K 19.04K
UBS Group AG 846 892 8.88K 12.97K 28.48K 12.94K 13.89K 12.61K 11.30K 11.15K 9.98K 15.94K 12.07K 132.36K 72.70K 33.38K 11.37K 25.68K 32.16K 15.46K
JPMorgan Chase & Co 1.36K 2.83K 9.90K 83.46K 125.69K 83.21K 87.14K 96.15K 68.50K 10.11K 15.59K 6.64K 8.42K 7.71K 7.04K 7.64K 8.13K 18.36K — 13.06K
Citigroup Inc 153 802 748 589 534 511 455 603 532 15.63K 128 762 668 630 689 913 2.60K 1.29K 1.29K 1.18K
T. Rowe Price Associates — 796.01K 685.88K 421.26K 417.34K 338.73K 318.08K 297.29K 593.05K 276.84K 401.65K 798.50K 1.72M 1.59M 1.54M 1.47M 1.38M 1.17M 1.03M 902.15K
Wells Fargo & Co 6.10K 6.00K — 1 — — 19 — 12 — — — 30 — — 200 200 200 200 200
Fidelity Management & Research (FMR) 461.63K 1.46M 803.75K 708.08K 664.81K 377.65K 287.15K 287.15K 266.35K 266.35K — — 150.52K 316 316 316 316 316 — —

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