APLT — APPLIED THERAPEUTICS INC
Reported value held$17.35M
Funds holding (latest)36
Sector—
APLT (APPLIED THERAPEUTICS INC) is tracked on HoldingsHub across five years of quarterly 13F filings. 36 funds have reported positions historically, with the sum of their latest reported stakes valued at $17.35M. No fund in our coverage reported a position in the latest filing period, which typically means the stock has fallen out of the tracked funds' portfolios rather than that it cannot be bought.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
| Fund | Quarter | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|---|
| Alkeon Capital Management history | Q3 2021 | 639.46K | $10.62M | 0.02% | New |
| PNC Financial Services history | Q3 2025 | 2.90M | $1.76M | 0.00% | New |
| Franklin Resources history | Q3 2025 | 2.00M | $1.21M | 0.00% | Hold |
| Manulife Financial history | Q3 2024 | 123.72K | $1.05M | 0.00% | Add |
| Vanguard Group history | Q4 2025 | 6.35M | $635.30K | 0.00% | Add |
| BlackRock Inc history | Q4 2025 | 3.25M | $325.15K | 0.00% | Reduce |
| Renaissance Technologies history | Q4 2025 | 2.71M | $270.62K | 0.00% | New |
| Norges Bank Investment Management history | Q4 2024 | 243.20K | $208.23K | 0.00% | New |
| Wellington Management Group history | Q4 2024 | 237.85K | $203.65K | 0.00% | Add |
| Geode Capital Management history | Q4 2025 | 1.49M | $149.33K | 0.00% | Add |
| Charles Schwab Investment Management history | Q2 2025 | 403.51K | $125.53K | 0.00% | Reduce |
| Two Sigma Investments history | Q3 2025 | 198.93K | $120.33K | 0.00% | Reduce |
| Millennium Management history | Q4 2025 | 1.05M | $105.19K | 0.00% | Reduce |
| Prudential Financial history | Q3 2024 | 11.28K | $95.88K | 0.00% | New |
| UBS Group AG history | Q4 2025 | 718.92K | $71.89K | 0.00% | Reduce |
| Deutsche Bank AG history | Q4 2025 | 622.23K | $62.22K | 0.00% | Hold |
| Principal Global Investors history | Q2 2024 | 11.58K | $54.09K | 0.00% | New |
| Balyasny Asset Management history | Q4 2023 | 10.61K | $35.53K | 0.00% | New |
| Marshall Wace history | Q4 2025 | 337.39K | $33.74K | 0.00% | Reduce |
| Janus Henderson Group history | Q4 2024 | 35.79K | $30.76K | 0.00% | Reduce |
New Positions (latest)
No fund opened a new position this quarter.
Fully Exited (vs previous quarter)
No tracked fund fully exited this quarter.
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q1 2021 | Q2 2021 | Q3 2021 | Q4 2021 | Q1 2022 | Q2 2022 | Q3 2022 | Q4 2022 | Q1 2023 | Q2 2023 | Q3 2023 | Q4 2023 | Q1 2024 | Q2 2024 | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vanguard Group | 834.17K | 844.88K | 850.30K | 851.14K | 610.87K | 514.22K | 453.26K | 796.56K | 855.15K | 997.00K | 1.43M | 3.23M | 3.01M | 5.32M | 5.24M | 5.55M | 5.89M | 4.73M | 5.10M | 6.35M |
| BlackRock Inc | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 6.94M | 9.30M | 9.55M | 5.22M | 3.84M | 3.25M |
| Renaissance Technologies | — | — | — | 17.60K | 282.20K | 264.18K | 334.29K | 317.98K | 219.80K | 407.38K | 415.48K | 653.09K | 175.80K | — | — | — | — | — | — | 2.71M |
| Geode Capital Management | — | — | 316.09K | 303.24K | 287.93K | 162.44K | 332.07K | 361.08K | 361.08K | 440.50K | 443.47K | 577.67K | 604.43K | 2.10M | 2.09M | 2.08M | 2.15M | 968.54K | 1.28M | 1.49M |
| Millennium Management | — | — | 11.93K | 124.96K | 108.10K | 360.81K | 99.48K | 61.94K | 181.83K | 47.76K | — | 600.04K | 926.42K | 110.91K | 377.37K | 1.33M | 109.10K | 1.94M | 1.91M | 1.05M |
| UBS Group AG | — | — | 21.21K | 74.42K | 22.01K | 25.86K | 27.15K | 11.37K | 73.70K | 106.64K | 108.38K | 120.21K | 152.76K | 172.06K | 283.69K | 441.77K | 505.11K | 830.64K | 1.91M | 718.92K |
| Deutsche Bank AG | — | — | 23.64K | 11.40K | 31.91K | — | — | — | — | — | — | — | 622.23K | 2.34M | 4.44M | 4.47M | 4.47M | 622.23K | 622.23K | 622.23K |
| Marshall Wace | — | — | — | — | — | — | — | — | — | — | — | 258.14K | — | — | 534.00K | 1.31M | 1.31M | 1.54M | 2.54M | 337.39K |
| BNY Mellon | — | — | 67.46K | 68.40K | 70.46K | — | — | — | — | — | — | 26.96K | — | 283.79K | 246.45K | 257.28K | 316.45K | 79.42K | 79.42K | 253.57K |
| Northern Trust Corp | — | — | 178.20K | 177.68K | 164.38K | 35.59K | 50.96K | 50.96K | 50.96K | 109.22K | 98.95K | 106.60K | 106.45K | 233.78K | 761.06K | 774.32K | 768.20K | 175.25K | 173.72K | 245.14K |
| Citadel Advisors | — | — | 25.40K | 76.16K | 42.88K | 96.04K | 22.20K | 36.17K | — | 22.53K | 30.97K | 156.11K | 129.81K | 175.95K | 486.38K | 1.16M | 303.70K | 752.29K | 252.10K | 192.70K |
| Morgan Stanley | — | — | 14.60K | 18.81K | 20.43K | 109.60K | 20.08K | 4.48K | 196 | 54.72K | 51.37K | 53.62K | 3.19M | 3.52M | 9.90M | 8.82M | 2.87M | 342.64K | 713.32K | 178.47K |
| Citigroup Inc | — | — | 3.68K | 5.50K | 2.80K | 9.08K | 101.94K | 293 | 353.14K | — | 65.98K | 219.93K | 118.80K | 21.18K | 69.67K | 79.84K | 75.84K | 7.44K | 6.84K | 163.45K |
| Goldman Sachs Group | — | — | 62.09K | 75.50K | 94.66K | 16.13K | 28.32K | — | — | — | — | 16.75K | 715.21K | 152.45K | 937.37K | 1.14M | 316.23K | 730.72K | 155.14K | 146.22K |
| Point72 Asset Management | — | — | 1.02M | 1.11M | 2.55M | 2.83M | 1.72M | 719.94K | 719.94K | 474.93K | 474.93K | 474.93K | — | — | — | — | — | — | — | 17.02K |
| AQR Capital Management | — | — | — | — | 85.06K | 13.91K | — | — | — | — | — | — | — | — | 218.52K | — | 572.31K | 286.92K | 109.69K | 13.41K |
| JPMorgan Chase & Co | — | — | 8.77K | 9.26K | 11.55K | 1.22K | 2.03K | 388 | 75.75K | 27.10K | 388 | 46.93K | 178.92K | 41.14K | 48.31K | 51.55K | 53.91K | 1.98K | 7.63K | 12.06K |
| Bank of America Corp | — | — | 14.54K | 36.03K | 20.19K | 4.39K | 458 | 129 | 365 | 1 | 228 | 44.63K | 35.55K | 229.86K | 314.91K | 167.41K | 44.41K | 18.17K | 11.67K | 3.11K |
| Fidelity Management & Research (FMR) | — | — | 2.41M | 2.24M | 903.29K | 4.01M | 3.20M | 2.97M | 2.97M | 2.64M | 2.64M | 2.43M | — | 1.10K | 2.40K | 176.04K | 69.96K | 17.83K | 17.48K | 184 |
| Two Sigma Investments | — | — | 29.13K | 28.43K | 280.27K | 178.25K | 181.60K | 177.77K | 89.15K | 24.55K | 69.35K | 286.00K | 155.16K | 43.34K | — | 293.81K | 960.59K | 594.53K | 198.93K | — |