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AMLX — AMYLYX PHARMACEUTICALS INC

Reported value held$995.92M
Funds holding (latest)40
SectorHealth Care
Funds holding (Q2 2026)31
Institutional value$804.54M · 44.86M sh
New / Add / Cut / Exit3 / 16 / 10 / 1
Top-5 / Top-10 concentration77.0% / 91.9%
Institutional holdings change Reducing -4.8% (-2.24M sh)
Institutional value change Up +23.2%

As of Q2 2026, 31 SEC-registered investment managers reported holding AMLX (AMYLYX PHARMACEUTICALS INC) in their latest 13F filings, with a combined reported value of $804.54M across 44.86M shares. That is -4.8% by share count (-2.24M shares) versus the previous quarter, while reported value moved +23.2%. Ownership is concentrated: the five largest holders account for 77.0% of reported value and the top ten for 91.9%.

Compared with the prior quarter, 3 opened new positions, 16 added to existing stakes, 10 trimmed, 1 exited entirely. 13F holdings are quarter-end snapshots, so these moves reflect positioning as of Q2 2026, not real-time trading.

AMLX is classified in the Health Care sector.

All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.

FundQuarterSharesValuePortfolio WeightChange
Fidelity Management & Research (FMR) history Q2 2026 16.73M $300.43M 0.01% Add
BlackRock Inc history Q2 2026 8.83M $158.53M 0.00% Hold
Vanguard Group history Q4 2025 5.80M $70.12M 0.00% Add
Janus Henderson Group history Q1 2026 4.99M $69.26M 0.03% Add
Morgan Stanley history Q2 2026 3.13M $56.23M 0.00% Add
Franklin Resources history Q2 2026 2.95M $52.99M 0.01% Add
Goldman Sachs Group history Q2 2026 2.86M $51.33M 0.01% Add
Viking Global Investors history Q4 2023 2.96M $43.61M 0.16% Hold
Geode Capital Management history Q2 2026 2.34M $41.95M 0.00% Add
JPMorgan Chase & Co history Q2 2026 1.86M $34.92M 0.00% New
Northern Trust Corp history Q2 2026 831.74K $14.94M 0.00% Add
Bank of America Corp history Q2 2026 821.84K $14.76M 0.00% Reduce
Charles Schwab Investment Management history Q2 2026 725.03K $13.02M 0.00% Add
Balyasny Asset Management history Q2 2026 684.97K $12.30M 0.02% Reduce
Two Sigma Investments history Q2 2026 593.43K $10.66M 0.01% Add
Deutsche Bank AG history Q2 2026 557.94K $10.02M 0.00% Reduce
BNY Mellon history Q2 2026 274.44K $4.93M 0.00% Add
UBS Group AG history Q2 2026 271.88K $4.88M 0.00% Reduce
Wellington Management Group history Q2 2026 212.84K $3.82M 0.00% Reduce
Farallon Capital Management history Q3 2024 1.15M $3.73M 0.02% Hold

View all 40 fund holders →

New Positions (Q2 2026)

Fully Exited (vs previous quarter)

Fund Position History — shares by quarter (top 20 funds)

FundQ1 2022Q2 2022Q3 2022Q4 2022Q1 2023Q2 2023Q3 2023Q4 2023Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Fidelity Management & Research (FMR) 88.12K 122.44K 336 7.80K 7.23K 448.98K 438.69K 1.44M 19.39K 56.38K 221.00K 731.36K 1.16M 3.05M 11.38M 16.52M 16.63M 16.73M
BlackRock Inc — — — — — — — — — — 2.55M 2.28M 2.39M 5.51M 7.14M 9.05M 8.83M 8.83M
Morgan Stanley 42.34K 43.11K 269.07K 484.47K 902.55K 1.05M 952.12K 2.83M 2.07M 924.46K 478.26K 464.22K 474.42K 486.89K 1.95M 2.36M 2.18M 3.13M
Franklin Resources — — — — — 28.49K 617.87K 1.33M 1.86M — — — — — — 1.20M 2.26M 2.95M
Goldman Sachs Group — — 379.40K 1.04M 1.37M 1.35M 1.19M 1.26M 2.94M 2.61M 1.61M 1.86M 2.00M 1.30M 2.01M 2.61M 2.63M 2.86M
Geode Capital Management 190.15K 231.42K 635.56K 853.91K 890.98K 938.00K 982.07K 1.03M 1.07M 468.87K 551.04K 567.90K 806.16K 1.69M 1.81M 2.17M 2.21M 2.34M
JPMorgan Chase & Co 4.50K 6.13K 19.26K 49.70K 43.60K 190.30K 90.97K 8.30K 409.76K 57.51K 140.56K 55.61K 54.07K 87.99K 35.84K 66.55K — 1.86M
Northern Trust Corp 82.17K 94.54K 285.81K 395.14K 463.88K 485.42K 425.78K 435.44K 425.57K 367.25K 95.35K 106.56K 139.33K 820.16K 822.24K 937.76K 779.91K 831.74K
Bank of America Corp 2.90K 16.57K 8.89K 63.37K 68.32K 117.21K 78.19K 120.33K 275.96K 477.52K 912.51K 2.43M 794.35K 451.81K 429.52K 1.34M 1.33M 821.84K
Charles Schwab Investment Management 73.03K 70.41K 240.74K 317.72K 320.09K 325.48K 365.86K 387.62K 435.90K 521.62K 302.27K 298.95K 372.85K 588.41K 645.18K 712.99K 716.23K 725.03K
Balyasny Asset Management 62.91K — 191.33K 645.55K 420.84K 1.60M 696.88K 19.70K — 22.89K 50.90K 50.25K 148.56K — 1.48M 858.68K 1.11M 684.97K
Two Sigma Investments — — — — — — — 43.80K 1.43M 1.30M 367.24K 651.52K 762.05K 558.85K 98.42K 344.40K 161.94K 593.43K
Deutsche Bank AG 5.35K 4.69K 14.98K 21.96K 31.32K 191.61K 24.42K 853.00K 756.17K 570.86K 570.86K 570.86K 570.86K 616.92K 1.37M 1.33M 1.27M 557.94K
BNY Mellon 26.45K 29.02K 116.94K 210.14K 204.66K 163.88K 163.59K 191.00K 198.03K — 23.68K — — 150.84K 182.96K 217.35K 251.10K 274.44K
UBS Group AG 4.16K 177 133.99K 31.38K 130.05K 101.97K 4.61K 39.01K 210.57K 30.14K 229.08K 643.52K 1.39M 1.25M 1.40M 543.32K 324.32K 271.88K
Wellington Management Group — — — 67.91K 108.43K 17.72K — 44.75K 33.93K — — 209.71K 290.68K 288.62K 236.20K 225.78K 241.55K 212.84K
Citadel Advisors 501.64K 1.08M 1.46M 196.96K 425.51K 1.03M 1.48M 2.60M 2.26M 1.55M 2.15M 2.23M 2.82M 1.29M 371.77K 456.87K 469.63K 189.39K
D. E. Shaw & Co — — 162.26K 1.38M 2.02M 1.59M 760.29K 546.97K 1.04M 1.31M 691.07K 306.74K 270.01K 151.50K 68.88K 73.22K 74.23K 174.28K
Norges Bank Investment Management — — — 81.20K — — — 116.40K — — — — — — — — — 159.90K
Invesco Ltd — — 261.54K 215.47K 22.94K 26.74K 29.84K 23.89K 24.35K — — — 45.69K 586.88K 810.64K 175.91K 171.62K 139.94K

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