AGLE — AEGLEA BIOTHERAPEUTICS INC
Reported value held$8.34M
Funds holding (latest)28
Sector—
AGLE (AEGLEA BIOTHERAPEUTICS INC) is tracked on HoldingsHub across five years of quarterly 13F filings. 28 funds have reported positions historically, with the sum of their latest reported stakes valued at $8.34M. No fund in our coverage reported a position in the latest filing period, which typically means the stock has fallen out of the tracked funds' portfolios rather than that it cannot be bought.
All figures on this page are computed from SEC Form 13F quarterly filings. 13F filers disclose long positions of $100,000 or more within 45 days of quarter end; short positions, options overlays and intra-quarter trades are not included, so treat the numbers as a quarterly snapshot of institutional ownership rather than real-time positioning.
Q2 2023 — 13 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Wellington Management Group history | 8.82M | $3.97M | 0.00% | New |
| Millennium Management history | 2.45M | $1.11M | 0.00% | Reduce |
| Vanguard Group history | 648.05K | $291.95K | 0.00% | Reduce |
| Geode Capital Management history | 600.46K | $270.50K | 0.00% | Hold |
| Goldman Sachs Group history | 558.65K | $251.67K | 0.00% | New |
| Northern Trust Corp history | 97.93K | $44.12K | 0.00% | Hold |
| Franklin Resources history | 31.36K | $14.13K | 0.00% | Hold |
| BNY Mellon history | 23.23K | $10.47K | 0.00% | Hold |
| Wells Fargo & Co history | 8.75K | $3.94K | 0.00% | Add |
| UBS Group AG history | 8.09K | $3.65K | 0.00% | Add |
| Morgan Stanley history | 3.31K | $1.49K | 0.00% | Reduce |
| JPMorgan Chase & Co history | 1.07K | $481 | 0.00% | Hold |
| Renaissance Technologies history | 393.00K | $177 | 0.00% | Add |
Q1 2023 — 13 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 2.00M | $579.30K | 0.00% | Hold |
| Geode Capital Management history | 600.46K | $174.13K | 0.00% | Hold |
| Two Sigma Investments history | 320.50K | $92.94K | 0.00% | Reduce |
| Northern Trust Corp history | 97.93K | $28.40K | 0.00% | Add |
| Bank of America Corp history | 35.23K | $10.22K | 0.00% | Add |
| Franklin Resources history | 31.36K | $9.10K | 0.00% | Hold |
| BNY Mellon history | 23.23K | $6.74K | 0.00% | Hold |
| Morgan Stanley history | 13.66K | $3.96K | 0.00% | Reduce |
| Wells Fargo & Co history | 8.22K | $2.38K | 0.00% | Add |
| Millennium Management history | 3.74M | $1.08K | 0.00% | Add |
| Renaissance Technologies history | 181.10K | $53 | 0.00% | Add |
| UBS Group AG history | 7 | $2 | 0.00% | Reduce |
| JPMorgan Chase & Co history | 1.07K | $0 | — | Hold |
Q4 2022 — 15 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 2.00M | $898.72K | 0.00% | Add |
| Two Sigma Investments history | 393.64K | $177.10K | 0.00% | Add |
| Northern Trust Corp history | 86.42K | $38.88K | 0.00% | Add |
| Morgan Stanley history | 80.46K | $36.20K | 0.00% | Reduce |
| Franklin Resources history | 31.36K | $14.11K | 0.00% | Hold |
| Citadel Advisors history | 30.57K | $13.75K | 0.00% | Reduce |
| BNY Mellon history | 23.23K | $10.45K | 0.00% | Hold |
| Prudential Financial history | 17.20K | $7.74K | 0.00% | New |
| Bank of America Corp history | 15.77K | $7.08K | 0.00% | Add |
| Millennium Management history | 3.13M | $1.41K | 0.00% | Add |
| Wells Fargo & Co history | 2.54K | $1.15K | 0.00% | Add |
| Geode Capital Management history | 600.46K | $270 | 0.00% | Add |
| Renaissance Technologies history | 151.10K | $68 | 0.00% | Reduce |
| UBS Group AG history | 8 | $4 | 0.00% | New |
| JPMorgan Chase & Co history | 1.07K | $0 | — | Reduce |
Q3 2022 — 15 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 1.89M | $993.00K | 0.00% | Reduce |
| Goldman Sachs Group history | 915.70K | $482.00K | 0.00% | Reduce |
| Millennium Management history | 814.67K | $429.00K | 0.00% | Add |
| Geode Capital Management history | 394.02K | $207.00K | 0.00% | Hold |
| Renaissance Technologies history | 249.80K | $131.00K | 0.00% | Reduce |
| Morgan Stanley history | 168.26K | $88.00K | 0.00% | Reduce |
| Two Sigma Investments history | 103.59K | $54.00K | 0.00% | Reduce |
| Citadel Advisors history | 75.88K | $40.00K | 0.00% | Reduce |
| Northern Trust Corp history | 69.21K | $36.00K | 0.00% | Hold |
| Franklin Resources history | 31.36K | $16.00K | 0.00% | Hold |
| BNY Mellon history | 23.23K | $12.00K | 0.00% | Reduce |
| Bank of America Corp history | 11.68K | $6.00K | 0.00% | Add |
| JPMorgan Chase & Co history | 3.65K | $2.00K | 0.00% | Add |
| Wells Fargo & Co history | 2.53K | $1.00K | 0.00% | Add |
| Citigroup Inc history | 633 | $0 | — | Reduce |
Q2 2022 — 19 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 1.95M | $984.00K | 0.00% | Reduce |
| Goldman Sachs Group history | 1.19M | $600.00K | 0.00% | Add |
| Renaissance Technologies history | 582.44K | $294.00K | 0.00% | Add |
| Millennium Management history | 521.91K | $264.00K | 0.00% | Add |
| D. E. Shaw & Co history | 476.40K | $241.00K | 0.00% | Add |
| Geode Capital Management history | 394.02K | $199.00K | 0.00% | Reduce |
| Two Sigma Investments history | 315.84K | $160.00K | 0.00% | Add |
| Morgan Stanley history | 293.83K | $148.00K | 0.00% | Add |
| Citadel Advisors history | 271.39K | $137.00K | 0.00% | Add |
| UBS Group AG history | 76.81K | $39.00K | 0.00% | Add |
| Northern Trust Corp history | 69.21K | $35.00K | 0.00% | Reduce |
| Franklin Resources history | 31.36K | $16.00K | 0.00% | Reduce |
| BNY Mellon history | 25.14K | $13.00K | 0.00% | Reduce |
| Bank of America Corp history | 7.30K | $4.00K | 0.00% | Reduce |
| Citigroup Inc history | 5.18K | $3.00K | 0.00% | Add |
| Legal & General Investment Management America history | 3.26K | $2.00K | 0.00% | Hold |
| Fidelity Management & Research (FMR) history | 1.49K | $1.00K | 0.00% | Add |
| JPMorgan Chase & Co history | 2.32K | $1.00K | 0.00% | Reduce |
| Wells Fargo & Co history | 2.44K | $1.00K | 0.00% | Reduce |
Q1 2022 — 25 funds
| Fund | Shares | Value | Portfolio Weight | Change |
|---|---|---|---|---|
| Vanguard Group history | 2.12M | $4.87M | 0.00% | Hold |
| Goldman Sachs Group history | 1.12M | $2.59M | 0.00% | Reduce |
| Geode Capital Management history | 692.22K | $1.59M | 0.00% | Add |
| Deutsche Bank AG history | 515.13K | $1.19M | 0.00% | Add |
| D. E. Shaw & Co history | 454.09K | $1.04M | 0.00% | Add |
| Millennium Management history | 423.91K | $975.00K | 0.00% | Add |
| Northern Trust Corp history | 333.74K | $768.00K | 0.00% | Reduce |
| Two Sigma Investments history | 216.60K | $498.00K | 0.00% | Add |
| Morgan Stanley history | 181.70K | $418.00K | 0.00% | Reduce |
| BNY Mellon history | 157.66K | $362.00K | 0.00% | Reduce |
| Marshall Wace history | 154.18K | $355.00K | 0.00% | Add |
| Renaissance Technologies history | 151.87K | $349.00K | 0.00% | Reduce |
| Charles Schwab Investment Management history | 106.81K | $246.00K | 0.00% | Add |
| Citadel Advisors history | 73.41K | $169.00K | 0.00% | Add |
| UBS Group AG history | 65.28K | $150.00K | 0.00% | Reduce |
| Franklin Resources history | 46.30K | $106.00K | 0.00% | New |
| AQR Capital Management history | 36.79K | $85.00K | 0.00% | New |
| JPMorgan Chase & Co history | 24.92K | $58.00K | 0.00% | Add |
| Bank of America Corp history | 18.00K | $41.00K | 0.00% | Reduce |
| Invesco Ltd history | 12.35K | $29.00K | 0.00% | Add |
| Manulife Financial history | 11.68K | $27.00K | 0.00% | Reduce |
| Wells Fargo & Co history | 7.03K | $16.00K | 0.00% | Reduce |
| Citigroup Inc history | 4.32K | $10.00K | 0.00% | Reduce |
| Legal & General Investment Management America history | 3.26K | $8.00K | 0.00% | Hold |
| Fidelity Management & Research (FMR) history | 121 | $0 | — | New |
New Positions (latest)
No fund opened a new position this quarter.
Fully Exited (vs previous quarter)
No tracked fund fully exited this quarter.
Fund Position History — shares by quarter (top 20 funds)
| Fund | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 | Q1 2022 | Q4 2021 | Q3 2021 | Q2 2021 | Q1 2021 |
|---|---|---|---|---|---|---|---|---|---|---|
| Wellington Management Group | 8.82M | — | — | — | — | — | — | — | — | — |
| Millennium Management | 2.45M | 3.74M | 3.13M | 814.67K | 521.91K | 423.91K | 228.68K | 535.22K | — | — |
| Vanguard Group | 648.05K | 2.00M | 2.00M | 1.89M | 1.95M | 2.12M | 2.12M | 2.11M | 2.10M | 2.17M |
| Geode Capital Management | 600.46K | 600.46K | 600.46K | 394.02K | 394.02K | 692.22K | 685.75K | 690.00K | — | — |
| Goldman Sachs Group | 558.65K | — | — | 915.70K | 1.19M | 1.12M | 1.13M | 1.14M | — | — |
| Northern Trust Corp | 97.93K | 97.93K | 86.42K | 69.21K | 69.21K | 333.74K | 349.69K | 365.70K | — | — |
| Franklin Resources | 31.36K | 31.36K | 31.36K | 31.36K | 31.36K | 46.30K | — | — | — | — |
| BNY Mellon | 23.23K | 23.23K | 23.23K | 23.23K | 25.14K | 157.66K | 159.27K | 159.49K | — | — |
| Wells Fargo & Co | 8.75K | 8.22K | 2.54K | 2.53K | 2.44K | 7.03K | 21.33K | 2.21K | — | — |
| UBS Group AG | 8.09K | 7 | 8 | — | 76.81K | 65.28K | 136.64K | 54.22K | — | — |
| Morgan Stanley | 3.31K | 13.66K | 80.46K | 168.26K | 293.83K | 181.70K | 196.22K | 194.22K | — | — |
| JPMorgan Chase & Co | 1.07K | 1.07K | 1.07K | 3.65K | 2.32K | 24.92K | 20.88K | 19.19K | — | — |
| Renaissance Technologies | 393.00K | 181.10K | 151.10K | 249.80K | 582.44K | 151.87K | 248.20K | 100.30K | — | — |
| Citadel Advisors | — | — | 30.57K | 75.88K | 271.39K | 73.41K | 31.70K | 10.20K | — | — |
| Fidelity Management & Research (FMR) | — | — | — | — | 1.49K | 121 | — | — | — | — |
| Deutsche Bank AG | — | — | — | — | — | 515.13K | 24.54K | 23.24K | — | — |
| Two Sigma Investments | — | 320.50K | 393.64K | 103.59K | 315.84K | 216.60K | 64.51K | — | — | — |
| AQR Capital Management | — | — | — | — | — | 36.79K | — | — | — | — |
| Bank of America Corp | — | 35.23K | 15.77K | 11.68K | 7.30K | 18.00K | 31.07K | 25.64K | — | — |
| Citigroup Inc | — | — | — | 633 | 5.18K | 4.32K | 11.89K | 7.13K | — | — |